Hypocretin-1 CSF levels in anti-Ma2 associated encephalitis

Neurology

Volumn 62, Issue 1, 2004, Pages 138-140

  Overeem, S ^a   Dalmau, J ^b   Bataller, L ^c   Nishino, S ^d   Mignot, E ^d   Verschuuren, J ^a   Lammers, G J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c HOSPITAL UNIVERSITARIO LA FE   (Spain)

^d STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; MA2 ANTIBODY; NEUROPEPTIDE; OREXIN A; UNCLASSIFIED DRUG;

ADULT; ANTIBODY DETECTION; ARTICLE; CEREBROSPINAL FLUID LEVEL; CLINICAL ARTICLE; DISEASE ASSOCIATION; ENCEPHALITIS; FEMALE; HUMAN; HUMAN TISSUE; MALE; NARCOLEPSY; NEUROENDOCRINE DISEASE; PARANEOPLASTIC SYNDROME; PRIORITY JOURNAL; PROTEIN DEFICIENCY; SOMNOLENCE; SYMPTOM;

EID: 0345830732     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.WNL.0000101718.92619.67     Document Type: Article

References (10)

1. Nishino S, Ripley B, Overeem S, et al. Low cerebrospinal fluid hypocretin (orexin) and altered energy homeostasis in human narcolepsy. Ann Neurol 2001;50:381-388.
2. Peyron C, Faraco J, Rogers W, et al. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat Med 2000;6:991-997.
3. Thannickal TC, Moore RY, Nienhuis R, et al. Reduced number of hypocretin neurons in human narcolepsy. Neuron 2000;27:469-474.
4. Mignot E, Lammers GJ, Ripley B, et al. The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. Arch Neurol 2002;59:1553-1562.
5. Overeem S, Mignot E, van Dijk JG, Lammers GJ. Narcolepsy: clinical features, new pathophysiologic insights, and future perspectives. J Clin Neurophysiol 2001;18:78-105.
6. Ripley B, Overeem S, Fujiki N, et al. CSF hypocretin/orexin levels in narcolepsy and other neurological conditions. Neurology 2001;57:2253-2258.
7. Black JL, Krahn LE, Pankratz VS, Michael S. Search for neuron-specific and nonneuron-specific antibodies in narcoleptic patients with and without HLA DQB1 *0602. Sleep 2002;25:719-723.
8. Rosenfeld MR, Eichen JG, Wade DF, Posner JB, Dalmau J. Molecular and clinical diversity in paraneoplastic immunity to Ma proteins. Ann Neurol 2001;50:339-348.
9. Voltz R, Gultekin SH, Rosenfeld MR, et al. A serologic marker of paraneoplastic limbic and brain-stem encephalitis in patients with testicular cancer. N Engl J Med 1999;340:1788-1795.
10. Scammell TE. The neurobiology, diagnosis, and treatment of narcolepsy. Ann Neurol 2003;53:154-166.