Gating of cystic fibrosis transmembrane conductance regulator chloride channels by adenosine triphosphate hydrolysis: Quantitative analysis of a cyclic gating scheme

Journal of General Physiology

Volumn 113, Issue 4, 1999, Pages 541-554

  Zeltwanger, Shawn ^a   Wang, Fei ^a   Wang, Guo Tang ^a   Gillis, Kevin D ^b   Hwang, Tzyh Chang ^a,c  

^a University of Missouri   (United States)

^b University of Missouri   (United States)

^c UNIVERSITY OF MISSOURI   (United States)

Author keywords

ATP binding cassette transporter; Cystic fibrosis; Gating mechanism; Patch clamp; Single channel kinetics

Indexed keywords

ADENOSINE TRIPHOSPHATE; CHLORIDE CHANNEL; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL MEMBRANE TRANSPORT; CHANNEL GATING; CONFORMATIONAL TRANSITION; CYSTIC FIBROSIS; ENZYME PHOSPHORYLATION; HYDROLYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PATCH CLAMP; PROTEIN DOMAIN; QUANTITATIVE ASSAY;

3T3 CELLS; ADENOSINE TRIPHOSPHATE; ALGORITHMS; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BINDING SITES; CHLORIDE CHANNELS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ELECTROPHYSIOLOGY; HYDROLYSIS; ION CHANNEL GATING; KINETICS; MICE; MODELS, BIOLOGICAL; NUCLEOTIDES; PATCH-CLAMP TECHNIQUES; PHOSPHORYLATION;

EID: 0032954806     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.113.4.541     Document Type: Article

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