-
1
-
-
0022489331
-
Ribosome-inactivating proteins up to date
-
Stirpe F, Barbieri L. Ribosome-inactivating proteins up to date. FEBS Lett 1986; 195: 1-8.
-
(1986)
FEBS Lett
, vol.195
, pp. 1-8
-
-
Stirpe, F.1
Barbieri, L.2
-
2
-
-
0024286995
-
The site of action of six different ribosome-inactivating proteins from plants on eukaryotic ribosomes: The RNA N-glycosidase activity of the proteins
-
Endo Y, Tsurugi K, Lambert JM. The site of action of six different ribosome-inactivating proteins from plants on eukaryotic ribosomes: the RNA N-glycosidase activity of the proteins. Biochem Biophys Res Commun 1988; 150: 1032-1036
-
(1988)
Biochem Biophys Res Commun
, vol.150
, pp. 1032-1036
-
-
Endo, Y.1
Tsurugi, K.2
Lambert, J.M.3
-
3
-
-
0024558887
-
Shiga toxin, Shiga-like toxin II variant, and ricin are all single-site RNA N-glycosidases of 28 S RNA when microinjected into Xenopus oocytes
-
Saxena SK, O'Brien AD, Ackerman EJ. Shiga toxin, Shiga-like toxin II variant, and ricin are all single-site RNA N-glycosidases of 28 S RNA when microinjected into Xenopus oocytes. J Biol Chem 1989; 264: 596-601.
-
(1989)
J Biol Chem
, vol.264
, pp. 596-601
-
-
Saxena, S.K.1
O'Brien, A.D.2
Ackerman, E.J.3
-
4
-
-
14744291476
-
Ribosome-inactivating proteins from plants: Present status and future prospects
-
NY
-
Stirpe F, Barbieri L, Battelli MG, Soria M, Lappi DA. Ribosome-inactivating proteins from plants: present status and future prospects. Biotechnology (NY) 1992; 10: 405-412
-
(1992)
Biotechnology
, vol.10
, pp. 405-412
-
-
Stirpe, F.1
Barbieri, L.2
Battelli, M.G.3
Soria, M.4
Lappi, D.A.5
-
5
-
-
0033922714
-
Penetration of protein toxins into cells
-
Falnes PO, Sandvig K. Penetration of protein toxins into cells. Curr Opin Cell Biol 2000; 12: 407-413
-
(2000)
Curr Opin Cell Biol
, vol.12
, pp. 407-413
-
-
Falnes, P.O.1
Sandvig, K.2
-
6
-
-
26244440267
-
-
Research Signpost eds. (Trivandrum-695 023, India)
-
Fabbrini MS, Flavell DJ, Ippoliti R. in "Bacterial, Plant and Animal toxins". Research Signpost eds. (Trivandrum-695 023, India) 2003; 69-99.
-
(2003)
Bacterial, Plant and Animal Toxins
, pp. 69-99
-
-
Fabbrini, M.S.1
Flavell, D.J.2
Ippoliti, R.3
-
7
-
-
0034877295
-
Shiga toxins
-
Sandvig K. Shiga toxins. Toxicon 2001; 39:1629-1635
-
(2001)
Toxicon
, vol.39
, pp. 1629-1635
-
-
Sandvig, K.1
-
8
-
-
0016696693
-
Ribosome inactivation by the toxic lectins abrin and ricin. Kinetics of the enzymic activity of the toxin A-chains
-
Olsnes S, Fernandez-Puentes C, Carrasco L, Vazquez D. Ribosome inactivation by the toxic lectins abrin and ricin. Kinetics of the enzymic activity of the toxin A-chains. Eur J Biochem 1975; 60: 281-288
-
(1975)
Eur J Biochem
, vol.60
, pp. 281-288
-
-
Olsnes, S.1
Fernandez-Puentes, C.2
Carrasco, L.3
Vazquez, D.4
-
9
-
-
0019309042
-
Entry of lethal doses of abrin, ricin and modeccin into the cytosol of HeLa cells
-
DOI 10.1016/0014-4827(80)90270-0
-
Eiklid K, Olsnes S, Pihl A. Entry of lethal doses of abrin, ricin and modeccin into the cytosol of HeLa cells. Exp Cell Res 1980; 126: 321-326 (Pubitemid 10041165)
-
(1980)
Experimental Cell Research
, vol.126
, Issue.2
, pp. 321-326
-
-
Eiklid, K.1
Olsnes, S.2
Pihl, A.3
-
10
-
-
0031727477
-
Involvement of both caspase-like proteases and serine proteases in apoptotic cell death induced by ricin, modeccin, diphtheria toxin, and Pseudomonas toxin
-
Komatsu N, Oda T, Muramatsu T. Involvement of both caspase-like proteases and serine proteases in apoptotic cell death induced by ricin, modeccin, diphtheria toxin, and pseudomonas toxin. J Biochem 1998; 124: 1038-1044 (Pubitemid 28544918)
-
(1998)
Journal of Biochemistry
, vol.124
, Issue.5
, pp. 1038-1044
-
-
Komatsu, N.1
Oda, T.2
Muramatsu, T.3
-
11
-
-
0343729921
-
Molecular mechanism of apoptosis induced by ricin in HeLa cells
-
Gan YH, Peng SQ, Liu HY. Molecular mechanism of apoptosis induced by ricin in HeLa cells. Acta Pharmacol Sin 2000; 21: 243-248
-
(2000)
Acta Pharmacol Sin
, vol.21
, pp. 243-248
-
-
Gan, Y.H.1
Peng, S.Q.2
Liu, H.Y.3
-
12
-
-
0037077029
-
Role of zinc ions in ricin-induced apoptosis in U937 cells
-
Tamura T, Sadakata N, Oda T, Muramatsu T. Role of zinc ions in ricin-induced apoptosis in U937 cells. Toxicol Lett 2002; 132: 141-151
-
(2002)
Toxicol Lett
, vol.132
, pp. 141-151
-
-
Tamura, T.1
Sadakata, N.2
Oda, T.3
Muramatsu, T.4
-
13
-
-
1342310838
-
Butyric acid sensitizes vero cells to ricin-induced apoptosis via accelerated activation of multiple signal transduction pathways
-
DOI 10.1247/csf.28.475
-
Tamura T, Tsuruta N, Hirano K, Yamaguchi K, Oda T. Butyric acid sensitizes Vero cells to ricin-induced apoptosis via accelerated activation of multiple signal transduction pathways. Cell Struct Funct 2003; 28: 475-485 (Pubitemid 38256615)
-
(2003)
Cell Structure and Function
, vol.28
, Issue.5
, pp. 475-485
-
-
Tamura, T.1
Tsuruta, N.2
Hirano, K.3
Yamaguchi, K.4
Oda, T.5
-
14
-
-
2442418980
-
Ricin Triggers Apoptotic Morphological Changes through Caspase-3 Cleavage of BAT3
-
Wu YH, Shih SF, Lin JY. Ricin Triggers Apoptotic Morphological Changes through Caspase-3 Cleavage of BAT3. J Biol Chem 2004; 279: 19264-19275
-
(2004)
J Biol Chem
, vol.279
, pp. 19264-19275
-
-
Wu, Y.H.1
Shih, S.F.2
Lin, J.Y.3
-
15
-
-
34347364663
-
Trichosanthin induced apoptosis in HL-60 cells via mitochondrial and endoplasmic reticulum stress signaling pathways
-
DOI 10.1016/j.bbagen.2007.04.007, PII S0304416507000979
-
Li J, Xia X, Ke Y, Nie H, Smith MA, Zhu X. Trichosanthin induced apoptosis in HL-60 cells via mitochondrial and endoplasmic reticulum stress signaling pathways. Biochim Biophys Acta 2007; 1770: 1169-1180 (Pubitemid 47009016)
-
(2007)
Biochimica et Biophysica Acta - General Subjects
, vol.1770
, Issue.8
, pp. 1169-1180
-
-
Li, J.1
Xia, X.2
Ke, Y.3
Nie, H.4
Smith, M.A.5
Zhu, X.6
-
16
-
-
48849111923
-
Shiga toxin 2 causes apoptosis in human brain microvascular endothelial cells via C/EBP homologous protein
-
Fujii J, Wood K, Matsuda F, et al. Shiga toxin 2 causes apoptosis in human brain microvascular endothelial cells via C/EBP homologous protein. Infect Immun 2008; 76: 3679-3689
-
(2008)
Infect Immun
, vol.76
, pp. 3679-3689
-
-
Fujii, J.1
Wood, K.2
Matsuda, F.3
-
17
-
-
59649088766
-
Saporin induces multiple death pathways in lymphoma cells with different intensity and timing as compared to ricin
-
Polito L, Bortolotti M, Farini V, Battelli MG, Barbieri L, Bolognesi A. Saporin induces multiple death pathways in lymphoma cells with different intensity and timing as compared to ricin. Int J Biochem Cell Biol 2009; 41: 1055-1061
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 1055-1061
-
-
Polito, L.1
Bortolotti, M.2
Farini, V.3
Battelli, M.G.4
Barbieri, L.5
Bolognesi, A.6
-
18
-
-
33747149327
-
Protein biotoxins of military significance
-
Hradec Kralove
-
Patocka J, Streda L. Protein biotoxins of military significance. Acta Medica (Hradec Kralove) 2006; 49: 3-11.
-
(2006)
Acta Medica
, vol.49
, pp. 3-11
-
-
Patocka, J.1
Streda, L.2
-
20
-
-
0034838167
-
Toxins as weapons of mass destruction. a comparison and contrast with biological-warfare and chemical-warfare agents
-
Madsen JM. Toxins as weapons of mass destruction. A comparison and contrast with biological-warfare and chemical-warfare agents. Clin Lab Med 2001; 21: 593-605.
-
(2001)
Clin Lab Med
, vol.21
, pp. 593-605
-
-
Madsen, J.M.1
-
21
-
-
0018780341
-
Ricin-a potent homicidal poison
-
Knight B. Ricin-a potent homicidal poison. Br Med J 1979; 1: 350-351
-
(1979)
Br Med J
, vol.1
, pp. 350-351
-
-
Knight, B.1
-
22
-
-
0019158721
-
Georgi Markov-death in a pellet
-
Crompton R, Gall D. Georgi Markov-death in a pellet. Med Leg J 1980; 48: 51-62.
-
(1980)
Med Leg J
, vol.48
, pp. 51-62
-
-
Crompton, R.1
Gall, D.2
-
23
-
-
0035214047
-
Toxin-labeled monoclonal antibodies
-
Kreitman RJ. Toxin-labeled monoclonal antibodies. Curr Pharm Biotechnol 2001; 2: 313-325
-
(2001)
Curr Pharm Biotechnol
, vol.2
, pp. 313-325
-
-
Kreitman, R.J.1
-
24
-
-
0041736005
-
Immunotoxin therapy of hematologic malignancies
-
Frankel AE, Neville DM, Bugge TA, Kreitman RJ, Leppla SH. Immunotoxin therapy of hematologic malignancies. Semin Oncol 2003; 30: 545-557
-
(2003)
Semin Oncol
, vol.30
, pp. 545-557
-
-
Frankel, A.E.1
Neville, D.M.2
Bugge, T.A.3
Kreitman, R.J.4
Leppla, S.H.5
-
25
-
-
33749432146
-
Immunotoxins in the treatment of hematologic malignancies
-
Kreitman RJ, Pastan I. Immunotoxins in the treatment of hematologic malignancies. Curr Drug Targets 2006; 7: 1301-1311
-
(2006)
Curr Drug Targets
, vol.7
, pp. 1301-1311
-
-
Kreitman, R.J.1
Pastan, I.2
-
27
-
-
0023219950
-
RNA N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomes
-
Endo Y, Tsurugi K. RNA N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomes. J Biol Chem 1987; 262: 8128-8130 (Pubitemid 17104265)
-
(1987)
Journal of Biological Chemistry
, vol.262
, Issue.17
, pp. 8128-8130
-
-
Endo, Y.1
Tsurugi, K.2
-
28
-
-
0023664263
-
The mechanism of action of ricin and related toxic lectins on eukaryotic ribosomes. the site and the characteristics of the modification in 28 S ribosomal RNA caused by the toxins
-
Endo Y, Mitsui K, Motizuki M, Tsurugi K. The mechanism of action of ricin and related toxic lectins on eukaryotic ribosomes. The site and the characteristics of the modification in 28 S ribosomal RNA caused by the toxins. J Biol Chem 1987; 262: 5908-5912
-
(1987)
J Biol Chem
, vol.262
, pp. 5908-5912
-
-
Endo, Y.1
Mitsui, K.2
Motizuki, M.3
Tsurugi, K.4
-
29
-
-
0023854742
-
Site of action of a Vero toxin (VT2) from Escherichia coli O157: H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins
-
Endo Y, Tsurugi K, Yutsudo T, Takeda Y, Ogasawara T, Igarashi K. Site of action of a Vero toxin (VT2) from Escherichia coli O157: H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins. Eur J Biochem 1988; 171: 45-50.
-
(1988)
Eur J Biochem
, Issue.171
, pp. 45-50
-
-
Endo, Y.1
Tsurugi, K.2
Yutsudo, T.3
Takeda, Y.4
Ogasawara, T.5
Igarashi, K.6
-
30
-
-
0028304470
-
Pokeweed antiviral protein (PAP) mutations which permit E.coli growth do not eliminate catalytic activity towards prokaryotic ribosomes
-
Chaddock JA, Lord JM, Hartley MR, Roberts LM. Pokeweed antiviral protein (PAP) mutations which permit E.coli growth do not eliminate catalytic activity towards prokaryotic ribosomes. Nucleic Acids Res 1994; 22: 1536-1540
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 1536-1540
-
-
Chaddock, J.A.1
Lord, J.M.2
Hartley, M.R.3
Roberts, L.M.4
-
31
-
-
0030044963
-
Major structural differences between pokeweed antiviral protein and ricin A-chain do not account for their differing ribosome specificity
-
Chaddock JA, Monzingo AF, Robertus JD, Lord JM, Roberts LM. Major structural differences between pokeweed antiviral protein and ricin A-chain do not account for their differing ribosome specificity. Eur J Biochem 1996; 235: 159-166
-
(1996)
Eur J Biochem
, vol.235
, pp. 159-166
-
-
Chaddock, J.A.1
Monzingo, A.F.2
Robertus, J.D.3
Lord, J.M.4
Roberts, L.M.5
-
32
-
-
0026592741
-
A ribosomal protein is specifically recognized by saporin, a plant toxin which inhibits protein synthesis
-
Ippoliti R, Lendaro E, Bellelli A, Brunori M. A ribosomal protein is specifically recognized by saporin, a plant toxin which inhibits protein synthesis. FEBS Lett 1992; 298: 145-148
-
(1992)
FEBS Lett
, vol.298
, pp. 145-148
-
-
Ippoliti, R.1
Lendaro, E.2
Bellelli, A.3
Brunori, M.4
-
33
-
-
0029013242
-
Ricin a chain can be chemically cross-linked to the mammalian ribosomal proteins L9 and L10e
-
Vater CA, Bartle LM, Leszyk JD, Lambert JM, Goldmacher VS. Ricin A chain can be chemically cross-linked to the mammalian ribosomal proteins L9 and L10e. J Biol Chem 1995; 270: 12933-12940
-
(1995)
J Biol Chem
, vol.270
, pp. 12933-12940
-
-
Vater, C.A.1
Bartle, L.M.2
Leszyk, J.D.3
Lambert, J.M.4
Goldmacher, V.S.5
-
34
-
-
0033524919
-
Pokeweed antiviral protein accesses ribosomes by binding to L3
-
DOI 10.1074/jbc.274.6.3859
-
Hudak KA, Dinman JD, Tumer NE. Pokeweed antiviral protein accesses ribosomes by binding to L3. J Biol Chem 1999; 274: 3859-3864 (Pubitemid 29077236)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.6
, pp. 3859-3864
-
-
Hudak, K.A.1
Dinman, J.D.2
Tumer, N.E.3
-
35
-
-
34247135324
-
Interaction between trichosanthin, a ribosome-inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses
-
Chan DS, Chu LO, Lee KM, et al. Interaction between trichosanthin, a ribosome-inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses. Nucleic Acids Res 2007; 35: 1660-1672
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 1660-1672
-
-
Chan, D.S.1
Chu, L.O.2
Lee, K.M.3
-
36
-
-
56749154533
-
The ribosomal stalk is required for ribosome binding, depurination of the rRNA and cytotoxicity of ricin a chain in Saccharomyces cerevisiae
-
Chiou JC, Li XP, Remacha M, Ballesta JP, Tumer NE. The ribosomal stalk is required for ribosome binding, depurination of the rRNA and cytotoxicity of ricin A chain in Saccharomyces cerevisiae. Mol Microbiol 2008; 70: 1441-1452
-
(2008)
Mol Microbiol
, vol.70
, pp. 1441-1452
-
-
Chiou, J.C.1
Li, X.P.2
Remacha, M.3
Ballesta, J.P.4
Tumer, N.E.5
-
37
-
-
59649126993
-
The C-terminal fragment of the ribosomal P protein complexed to trichosanthin reveals the interaction between the ribosome-inactivating protein and the ribosome
-
Too PH, Ma MK, Mak AN, et al. The C-terminal fragment of the ribosomal P protein complexed to trichosanthin reveals the interaction between the ribosome-inactivating protein and the ribosome. Nucleic Acids Res 2009; 37: 602-610
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 602-610
-
-
Too, P.H.1
Ma, M.K.2
Mak, A.N.3
-
38
-
-
0036185561
-
Real-time kinetic analyses of the interaction of ricin toxin A-chain with ribosomes prove a conformational change involved in complex formation
-
Honjo E, Watanabe K, Tsukamoto T. Real-time kinetic analyses of the interaction of ricin toxin A-chain with ribosomes prove a conformational change involved in complex formation. J Biochem 2002; 131: 267-275 (Pubitemid 34194364)
-
(2002)
Journal of Biochemistry
, vol.131
, Issue.2
, pp. 267-275
-
-
Honjo, E.1
Watanabe, K.2
Tsukamoto, T.3
-
39
-
-
0025939115
-
Structure of ricin B-chain at 2.5 Å resolution
-
Rutenber E, Robertus JD. Structure of ricin B-chain at 2.5 Å resolution. Proteins 1991; 10: 260-269
-
(1991)
Proteins
, vol.10
, pp. 260-269
-
-
Rutenber, E.1
Robertus, J.D.2
-
40
-
-
0027340580
-
The 2.5 Å structure of pokeweed antiviral protein
-
Monzingo AF, Collins EJ, Ernst SR, Irvin JD, Robertus JD. The 2.5 Å structure of pokeweed antiviral protein. J Mol Biol 1993; 233: 705-715
-
(1993)
J Mol Biol
, vol.233
, pp. 705-715
-
-
Monzingo, A.F.1
Collins, E.J.2
Ernst, S.R.3
Irvin, J.D.4
Robertus, J.D.5
-
41
-
-
43949154367
-
Refined structure of trichosanthin at 1.73 Å resolution
-
Gao B, Ma XQ, Wang YP, Chen SZ, Wu S, Dong YC. Refined structure of trichosanthin at 1.73 Å resolution. Sci China B 1994; 37: 59-73.
-
(1994)
Sci China B
, vol.37
, pp. 59-73
-
-
Gao, B.1
Ma, X.Q.2
Wang, Y.P.3
Chen, S.Z.4
Wu, S.5
Dong, Y.C.6
-
42
-
-
0028177695
-
The N-glycosidase mechanism of ribosome-inactivating proteins implied by crystal structures of alpha-momorcharin
-
DOI 10.1016/S0969-2126(00)00004-6
-
Ren J, Wang Y, Dong Y, Stuart DI. The N-glycosidase mechanism of ribosome-inactivating proteins implied by crystal structures of alpha-momorcharin. Structure 1994; 2: 7-16. (Pubitemid 2036417)
-
(1994)
Structure
, vol.2
, Issue.1
, pp. 7-16
-
-
Ren, J.1
Wang, Y.2
Dong, Y.3
Stuart, D.I.4
-
43
-
-
0029114697
-
Crystal structure of abrin-a at 2.14 Å
-
Tahirov TH, Lu TH, Liaw YC, Chen YL, Lin JY. Crystal structure of abrin-a at 2.14 Å. J Mol Biol 1995; 250: 354-367.
-
(1995)
J Mol Biol
, vol.250
, pp. 354-367
-
-
Tahirov, T.H.1
Lu, T.H.2
Liaw, Y.C.3
Chen, Y.L.4
Lin, J.Y.5
-
44
-
-
0029090073
-
-
Erratum in
-
Erratum in: J Mol Biol 1995; 252: 154-167
-
(1995)
J Mol Biol
, vol.252
, pp. 154-167
-
-
-
45
-
-
0029144596
-
X-ray structure of gelonin at 1.8 Å resolution
-
Hosur MV, Nair B, Satyamurthy P, Misquith S, Surolia A, Kannan KK. X-ray structure of gelonin at 1.8 Å resolution. J Mol Biol 1995; 250: 368-380
-
(1995)
J Mol Biol
, vol.250
, pp. 368-380
-
-
Hosur, M.V.1
Nair, B.2
Satyamurthy, P.3
Misquith, S.4
Surolia, A.5
Kannan, K.K.6
-
46
-
-
0034737565
-
The crystal structure of saporin SO6 from Saponaria officinalis and its interaction with the ribosome
-
DOI 10.1016/S0014-5793(00)01325-9, PII S0014579300013259
-
Savino C, Federici L, Ippoliti R, Lendaro E, Tsernoglou D. The crystal structure of saporin SO6 from Saponaria officinalis and its interaction with the ribosome. FEBS Lett 2000; 470: 239-243 (Pubitemid 30169271)
-
(2000)
FEBS Letters
, vol.470
, Issue.3
, pp. 239-243
-
-
Savino, C.1
Federici, L.2
Ippoliti, R.3
Lendaro, E.4
Tsernoglou, D.5
-
47
-
-
3042658236
-
The structure of ribosome inactivating proteins
-
Robertus JD, Monzingo AF. The structure of ribosome inactivating proteins. Mini Rev Med Chem 2004; 4: 477-486
-
(2004)
Mini Rev Med Chem
, vol.4
, pp. 477-486
-
-
Robertus, J.D.1
Monzingo, A.F.2
-
48
-
-
7044261951
-
High resolution X-ray structure and potent anti-HIV activity of recombinant dianthin antiviral protein
-
Kurinov IV, Rajamohan F, Uckun FM. High resolution X-ray structure and potent anti-HIV activity of recombinant dianthin antiviral protein. Arzneimittelforschung 2004; 54: 692-702. (Pubitemid 39422848)
-
(2004)
Arzneimittel-Forschung/Drug Research
, vol.54
, Issue.10
, pp. 692-702
-
-
Kurinov, I.V.1
Rajamohan, F.2
Uckun, F.M.3
-
49
-
-
12844250789
-
The 1.4 angstroms structure of dianthin 30 indicates a role of surface potential at the active site of type 1 ribosome inactivating proteins
-
DOI 10.1016/j.jsb.2004.11.007, PII S1047847704002187
-
Fermani S, Falini G, Ripamonti A, Polito L, Stirpe F, Bolognesi A. The 1.4 angstroms structure of dianthin 30 indicates a role of surface potential at the active site of type 1 ribosome inactivating proteins. J Struct Biol 2005; 149: 204-212 (Pubitemid 40170102)
-
(2005)
Journal of Structural Biology
, vol.149
, Issue.2
, pp. 204-212
-
-
Fermani, S.1
Falini, G.2
Ripamonti, A.3
Polito, L.4
Stirpe, F.5
Bolognesi, A.6
-
50
-
-
20144364945
-
Crystal structure of Himalayan mistletoe ribosome-inactivating protein reveals the presence of a natural inhibitor and a new functionally active sugar-binding site
-
DOI 10.1074/jbc.M500735200
-
Mishra V, Bilgrami S, Sharma RS, et al. Crystal structure of himalayan mistletoe ribosome-inactivating protein reveals the presence of a natural inhibitor and a new functionally active sugar-binding site. J Biol Chem 2005; 280: 20712-20721 (Pubitemid 40776776)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.21
, pp. 20712-20721
-
-
Mishra, V.1
Bilgrami, S.2
Sharma, R.S.3
Kaur, P.4
Yadav, S.5
Krauspenhaar, R.6
Betzel, C.7
Voelter, W.8
Babu, C.R.9
Singh, T.P.10
-
51
-
-
34248590284
-
X-ray sequence and crystal structure of luffaculin 1, a novel type 1 ribosome-inactivating protein
-
Hou X, Chen M, Chen L, Meehan EJ, Xie J, Huang M. X-ray sequence and crystal structure of luffaculin 1, a novel type 1 ribosome-inactivating protein. BMC Struct Biol 2007; 7: 29-39.
-
(2007)
BMC Struct Biol
, vol.7
, pp. 29-39
-
-
Hou, X.1
Chen, M.2
Chen, L.3
Meehan, E.J.4
Xie, J.5
Huang, M.6
-
52
-
-
40549129706
-
Atomic resolution (1.1 Å) structure of the ribosome-inactivating protein PD-L4 from Phytolacca dioica L. leaves
-
Ruggiero A, Chambery A, Di Maro A, Parente A, Berisio R. Atomic resolution (1.1 Å) structure of the ribosome-inactivating protein PD-L4 from Phytolacca dioica L. leaves. Proteins 2008; 71: 8-15.
-
(2008)
Proteins
, vol.71
, pp. 8-15
-
-
Ruggiero, A.1
Chambery, A.2
Di Maro, A.3
Parente, A.4
Berisio, R.5
-
53
-
-
42749094248
-
Pokeweed antiviral protein region Gly209-Lys225 is critical for RNA N-glycosidase activity of the prokaryotic ribosome
-
Nagasawa Y, Fujii K, Yoshikawa T, Kobayashi Y, Kondo T. Pokeweed antiviral protein region Gly209-Lys225 is critical for RNA N-glycosidase activity of the prokaryotic ribosome. Phytochemistry 2008; 69: 1653-1660
-
(2008)
Phytochemistry
, vol.69
, pp. 1653-1660
-
-
Nagasawa, Y.1
Fujii, K.2
Yoshikawa, T.3
Kobayashi, Y.4
Kondo, T.5
-
54
-
-
51749083943
-
Atomic resolution structure of cucurmosin, a novel type 1 ribosome-inactivating protein from the sarcocarp of Cucurbita moschata
-
Hou X, Meehan EJ, Xie J, Huang M, Chen M, Chen L. Atomic resolution structure of cucurmosin, a novel type 1 ribosome-inactivating protein from the sarcocarp of Cucurbita moschata. J Struct Biol 2008; 164: 81-87
-
(2008)
J Struct Biol
, vol.164
, pp. 81-87
-
-
Hou, X.1
Meehan, E.J.2
Xie, J.3
Huang, M.4
Chen, M.5
Chen, L.6
-
55
-
-
58949083855
-
Crystal structure of native cinnamomin isoform III and its comparison with other ribosome inactivating proteins
-
Azzi A, Wang T, Zhu DW, Zou YS, Liu WY, Lin SX. Crystal structure of native cinnamomin isoform III and its comparison with other ribosome inactivating proteins. Proteins 2009; 74: 250-255
-
(2009)
Proteins
, vol.74
, pp. 250-255
-
-
Azzi, A.1
Wang, T.2
Zhu, D.W.3
Zou, Y.S.4
Liu, W.Y.5
Lin, S.X.6
-
56
-
-
0034022958
-
A novel mechanism for inhibition of translation by pokeweed antiviral protein: Depurination of the capped RNA template
-
DOI 10.1017/S1355838200991337
-
Hudak KA, Wang P, Tumer NE. A novel mechanism for inhibition of translation by pokeweed antiviral protein: depurination of the capped RNA template. RNA 2000; 6: 369-380 (Pubitemid 30161281)
-
(2000)
RNA
, vol.6
, Issue.3
, pp. 369-380
-
-
Hudak, K.A.1
Wang, P.2
Tumer, N.E.3
-
57
-
-
0034647855
-
Polynucleotide:adenosine glycosidase activity of saporin-L1: Effect on various forms of mammalian DNA
-
DOI 10.1016/S0167-4838(00)00077-7, PII S0167483800000777
-
Barbieri L, Valbonesi P, Govoni M, Pession A, Stirpe F. Polynucleotide:adenosine glycosidase activity of saporin-L1: effect on various forms of mammalian DNA. Biochim Biophys Acta 2000; 1480: 258-266 (Pubitemid 30427403)
-
(2000)
Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology
, vol.1480
, Issue.1-2
, pp. 258-266
-
-
Barbieri, L.1
Valbonesi, P.2
Govoni, M.3
Pession, A.4
Stirpe, F.5
-
58
-
-
0034924485
-
Ribosome-inactivating proteins from plants: More than RNA N-glycosidases?
-
Peumans WJ, Hao Q, Van Damme EJ. Ribosome-inactivating proteins from plants: more than RNA N-glycosidases? FASEB J 2001; 15: 1493-1506
-
(2001)
FASEB J
, vol.15
, pp. 1493-1506
-
-
Peumans, W.J.1
Hao, Q.2
Van Damme, E.J.3
-
59
-
-
0036187197
-
Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells
-
DOI 10.1096/fj.01-0521com
-
Brigotti M, Alfieri R, Sestili P, et al. Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells. FASEB J 2002; 16: 365-372 (Pubitemid 34195297)
-
(2002)
FASEB Journal
, vol.16
, Issue.3
, pp. 365-372
-
-
Brigotti, M.1
Alfieri, R.2
Sestili, P.3
Bonelli, M.4
Petronini, P.G.5
Guidarelli, A.6
Barbieri, L.7
Stirpe, F.8
Sperti, S.9
-
60
-
-
0013001418
-
The cytotoxic activity of ribosome-inactivating protein saporin-6 is attributed to its rRNA N-glycosidase and internucleosomal DNA fragmentation activities
-
DOI 10.1074/jbc.M207389200
-
Bagga S, Seth D, Batra JK. The cytotoxic activity of ribosomeinactivating protein saporin-6 is attributed to its rRNA N-glycosidase and internucleosomal DNA fragmentation activities. J Biol Chem 2003; 278: 4813-4820 (Pubitemid 36800985)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.7
, pp. 4813-4820
-
-
Bagga, S.1
Seth, D.2
Batra, J.K.3
-
61
-
-
0037434897
-
Ribosome-inactivating proteins depurinate poly(ADP-ribosyl)ated poly(ADP-ribose) polymerase and have transforming activity for 3T3 fibroblasts
-
DOI 10.1016/S0014-5793(03)00176-5
-
Barbieri L, Brigotti M, Perocco P, et al. Ribosome-inactivating proteins depurinate poly(ADP-ribosyl)ated poly(ADP-ribose) polymerase and have transforming activity for 3T3 fibroblasts. FEBS Lett 2003; 538: 178-182 (Pubitemid 36287447)
-
(2003)
FEBS Letters
, vol.538
, Issue.1-3
, pp. 178-182
-
-
Barbieri, L.1
Brigotti, M.2
Perocco, P.3
Carnicelli, D.4
Ciani, M.5
Mercatali, L.6
Stirpe, F.7
-
62
-
-
4544287655
-
1 targets single-stranded regions of nucleic acids independent of sequence or structural motifs
-
DOI 10.1074/jbc.M400105200
-
Park SW, Vepachedu R, Owens RA, Vivanco JM. The N-glycosidase activity of the ribosome-inactivating protein ME1 targets single-stranded regions of nucleic acids independent of sequence or structural motifs. J Biol Chem 2004; 279: 34165-34174 (Pubitemid 39318039)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.33
, pp. 34165-34174
-
-
Park, S.-W.1
Vepachedu, R.2
Owens, R.A.3
Vivanco, J.M.4
-
63
-
-
13944280312
-
Mitochondrial DNA D-loop as a new target of Saporin 6 nuclease activity
-
DOI 10.1016/j.toxicon.2004.12.007
-
Gasperi-Campani A, Brognara I, Baiocchi D, Roncuzzi L. Mitochondrial DNA D-loop as a new target of Saporin 6 nuclease activity. Toxicon 2005; 45: 475-480 (Pubitemid 40269937)
-
(2005)
Toxicon
, vol.45
, Issue.4
, pp. 475-480
-
-
Gasperi-Campani, A.1
Brognara, I.2
Baiocchi, D.3
Roncuzzi, L.4
-
64
-
-
57749090370
-
Depurination of Brome mosaic virus RNA3 in vivo results in translation-dependent accelerated degradation of the viral RNA
-
Gandhi R, Manzoor M, Hudak KA. Depurination of Brome mosaic virus RNA3 in vivo results in translation-dependent accelerated degradation of the viral RNA. J Biol Chem 2008; 283: 32218-32228
-
(2008)
J Biol Chem
, vol.283
, pp. 32218-32228
-
-
Gandhi, R.1
Manzoor, M.2
Hudak, K.A.3
-
65
-
-
0032965441
-
Mistletoe lectin dissociates into catalytic and binding subunits before translocation across the membrane to the cytoplasm
-
DOI 10.1016/S0014-5793(99)00639-0, PII S0014579399006390
-
Agapov II, Tonevitsky AG, Moysenovich MM, Maluchenko NV, Weyhenmeyer R, Kirpichnikov MP. Mistletoe lectin dissociates into catalytic and binding subunits before translocation across the membrane to the cytoplasm. FEBS Lett 1999; 452: 211-214 (Pubitemid 29301746)
-
(1999)
FEBS Letters
, vol.452
, Issue.3
, pp. 211-214
-
-
Agapov, I.I.1
Tonevitsky, A.G.2
Moysenovich, M.M.3
Maluchenko, N.V.4
Weyhenmeyer, R.5
Kirpichnikov, M.P.6
-
66
-
-
11144357038
-
Reductive activation of ricin and ricin A-chain immunotoxins by protein disulfide isomerase and thioredoxin reductase
-
DOI 10.1016/j.bcp.2004.01.013, PII S0006295204000668
-
Bellisola G, Fracasso G, Ippoliti R, et al. Reductive activation of ricin and ricin A-chain immunotoxins by protein disulfide isomerase and thioredoxin reductase. Biochem Pharmacol 2004; 67: 1721-1731 (Pubitemid 38479850)
-
(2004)
Biochemical Pharmacology
, vol.67
, Issue.9
, pp. 1721-1731
-
-
Bellisola, G.1
Fracasso, G.2
Ippoliti, R.3
Menestrina, G.4
Rosen, A.5
Solda, S.6
Udali, S.7
Tomazzolli, R.8
Tridente, G.9
Colombatti, M.10
-
67
-
-
0028956879
-
Cytotoxic effects of ricin without an interchain disulfide bond: Genetic modification and chemical cross-linking studies
-
Mohanraj D, Ramakrishnan S. Cytotoxic effects of ricin without an interchain disulfide bond: genetic modification and chemical cross-linking studies. Biochim Biophys Acta 1995; 1243: 399-406.
-
(1995)
Biochim Biophys Acta
, vol.1243
, pp. 399-406
-
-
Mohanraj, D.1
Ramakrishnan, S.2
-
69
-
-
0028098025
-
Ricin: Structure, mode of action, and some current applications
-
Lord JM, Roberts LM, Robertus JD. Ricin: structure, mode of action, and some current applications FASEB J 1994; 8: 201-208
-
(1994)
FASEB J
, vol.8
, pp. 201-208
-
-
Lord, J.M.1
Roberts, L.M.2
Robertus, J.D.3
-
71
-
-
4344610200
-
Cytotoxic ribosome-inactivating lectins from plants
-
Hartley MR, Lord JM. Cytotoxic ribosome-inactivating lectins from plants. Biochim Biophys Acta 2004; 1701: 1-14.
-
(2004)
Biochim Biophys Acta
, vol.1701
, pp. 1-14
-
-
Hartley, M.R.1
Lord, J.M.2
-
72
-
-
4043074939
-
The history of ricin, abrin and related toxins
-
DOI 10.1016/j.toxicon.2004.05.003, PII S0041010104001898
-
Olsnes S. The history of ricin, abrin and related toxins. Toxicon 2004; 44: 361-370 (Pubitemid 39070638)
-
(2004)
Toxicon
, vol.44
, Issue.4
, pp. 361-370
-
-
Olsnes, S.1
-
73
-
-
27744564219
-
Ricin poisoning: A comprehensive review
-
Audi J, Belson M, Patel M, Schier J, Osterloh J. Ricin poisoning: a comprehensive review. JAMA 2005; 294: 2342-2351
-
(2005)
JAMA
, vol.294
, pp. 2342-2351
-
-
Audi, J.1
Belson, M.2
Patel, M.3
Schier, J.4
Osterloh, J.5
-
74
-
-
0028099436
-
X-ray structure of recombinant ricin A-chain at 1.8 Å resolution
-
DOI 10.1006/jmbi.1994.1739
-
Weston SA, Tucker AD, Thatcher DR, Derbyshire DJ, Pauptit RA. X-ray structure of recombinant ricin A-chain at 1.8 Å resolution. J Mol Biol 1994; 244: 410-422 (Pubitemid 24378166)
-
(1994)
Journal of Molecular Biology
, vol.244
, Issue.4
, pp. 410-422
-
-
Weston, S.A.1
Tucker, A.D.2
Thatcher, D.R.3
Derbyshire, D.J.4
Pauptit, R.A.5
-
76
-
-
0027512828
-
Structure of recombinant ricin a chain at 2.3 Å
-
Mlsna D, Monzingo AF, Katzin BJ, Ernst S, Robertus JD. Structure of recombinant ricin A chain at 2.3 Å. Protein Sci 1993; 2: 429-435 (Pubitemid 23071291)
-
(1993)
Protein Science
, vol.2
, Issue.3
, pp. 429-435
-
-
Mlsna, D.1
Monzingo, A.F.2
Katzin, B.J.3
Ernst, S.4
Robertus, J.D.5
-
77
-
-
0032544216
-
Ricin A-chain: Kinetics, mechanism, and RNA stem-loop inhibitors
-
Chen XY, Link TM, Schramm VL. Ricin A-chain: kinetics, mechanism, and RNA stem-loop inhibitors. Biochemistry 1998; 37: 11605-11613
-
(1998)
Biochemistry
, vol.37
, pp. 11605-11613
-
-
Chen, X.Y.1
Link, T.M.2
Schramm, V.L.3
-
78
-
-
0035849504
-
Ricin A-chain inhibitors resembling the oxacarbenium ion transition state
-
DOI 10.1021/bi010499p
-
Tanaka KS, Chen XY, Ichikawa Y, Tyler PC, Furneaux RH, Schramm VL. Ricin A-chain inhibitors resembling the oxacarbenium ion transition state. Biochemistry 2001; 40: 6845-6851 (Pubitemid 32538230)
-
(2001)
Biochemistry
, vol.40
, Issue.23
, pp. 6845-6851
-
-
Tanaka, K.S.E.1
Chen, X.-Y.2
Ichikawa, Y.3
Tyler, P.C.4
Furneaux, R.H.5
Schramm, V.L.6
-
79
-
-
2142662114
-
Inhibition of Ricin A-Chain with Pyrrolidine Mimics of the Oxacarbenium Ion Transition State
-
DOI 10.1021/bi0498499
-
Roday S, Amukele T, Evans GB, Tyler PC, Furneaux RH, Schramm VL. Inhibition of ricin A-chain with pyrrolidine mimics of the oxacarbenium ion transition state. Biochemistry 2004; 43: 4923-4933 (Pubitemid 38544446)
-
(2004)
Biochemistry
, vol.43
, Issue.17
, pp. 4923-4933
-
-
Roday, S.1
Amukele, T.2
Evans, G.B.3
Tyler, P.C.4
Furneaux, R.H.5
Schramm, V.L.6
-
80
-
-
1642539986
-
The effect of mutations surrounding and within the active site on the catalytic activity of ricin a chain
-
DOI 10.1046/j.1432-1033.2003.03914.x
-
Marsden CJ, Fülöp V, Day PJ, Lord JM. The effect of mutations surrounding and within the active site on the catalytic activity of ricin A chain. Eur J Biochem 2004; 271: 153-162 (Pubitemid 38122174)
-
(2004)
European Journal of Biochemistry
, vol.271
, Issue.1
, pp. 153-162
-
-
Marsden, C.J.1
Fulop, V.2
Day, P.J.3
Lord, J.M.4
-
81
-
-
0019432633
-
Ricin B chain is a product of gene duplication
-
Villafranca JE, Robertus JD. Ricin B chain is a product of gene duplication. J Biol Chem 1981; 256: 554-556
-
(1981)
J Biol Chem
, vol.256
, pp. 554-556
-
-
Villafranca, J.E.1
Robertus, J.D.2
-
83
-
-
0032540940
-
Transport of apically but not basolaterally internalized ricin to the Golgi apparatus is stimulated by 8-Br-cAMP in MDCK cells
-
DOI 10.1016/S0014-5793(98)00754-6, PII S0014579398007546
-
Llorente A, van Deurs B, Sandvig K. Transport of apically but not basolaterally internalized ricin to the Golgi apparatus is stimulated by 8-Br-cAMP in MDCK cells. FEBS Lett 1998; 431: 200-204 (Pubitemid 28334216)
-
(1998)
FEBS Letters
, vol.431
, Issue.2
, pp. 200-204
-
-
Llorente, A.1
Van Deurs, B.2
Sandvig, K.3
-
84
-
-
0031868419
-
Expression of mutant dynamin rotects cells against diphtheria toxin but not against ricin
-
Simpson JC, Smith DC, Roberts LM, Lord JM. Expression of mutant dynamin rotects cells against diphtheria toxin but not against ricin. Exp Cell Res 1998; 239: 293-300.
-
(1998)
Exp Cell Res
, vol.239
, pp. 293-300
-
-
Simpson, J.C.1
Smith, D.C.2
Roberts, L.M.3
Lord, J.M.4
-
85
-
-
0032931988
-
Extraction of cholesterol with methyl-betacyclodextrin perturbs formation of clathrin-coated endocytic vesicles
-
Rodal SK, Skretting G, Garred Ø, Vilhardt F, van Deurs B, Sandvig, K. Extraction of cholesterol with methyl-betacyclodextrin perturbs formation of clathrin-coated endocytic vesicles Mol Biol Cell 1999; 10: 961-974
-
(1999)
Mol Biol Cell
, vol.10
, pp. 961-974
-
-
Rodal, S.K.1
Skretting, G.2
Garred, Ø.3
Vilhardt, F.4
Van Deurs, B.5
Sandvig, K.6
-
86
-
-
2442688008
-
Pathways followed by protein toxins into cells
-
DOI 10.1078/1438-4221-00294
-
Sandvig K, Spilsberg B, Lauvrak SU, Torgersen ML, Iversen TG, van Deurs B. Pathways followed by protein toxins into cells. Int J Med Microbiol 2004; 293: 483-490 (Pubitemid 38667570)
-
(2004)
International Journal of Medical Microbiology
, vol.293
, Issue.7-8
, pp. 483-490
-
-
Sandvig, K.1
Spilsberg, B.2
Lauvrak, S.U.3
Torgersen, M.L.4
Iversen, T.-G.5
Van Deurs, B.6
-
87
-
-
33747058472
-
Depletion of sphingolipids facilitates endosome to Golgi transport of ricin
-
DOI 10.1111/j.1600-0854.2006.00456.x
-
Grimmer S, Spilsberg B, Hanada K, Sandvig K. Depletion of sphingolipids facilitates endosome to Golgi transport of ricin. Traffic 2006; 7: 1243-1253 (Pubitemid 44207838)
-
(2006)
Traffic
, vol.7
, Issue.9
, pp. 1243-1253
-
-
Grimmer, S.1
Spilsberg, B.2
Hanada, K.3
Sandvig, K.4
-
88
-
-
0026735969
-
Cell surface and intracellular functions for ricin galactose binding
-
Newton DL, Wales R, Richardson PT, et al. Cell surface and intracellular functions for ricin galactose binding. J Biol Chem 1992; 267: 11917-11922
-
(1992)
J Biol Chem
, vol.267
, pp. 11917-11922
-
-
Newton, D.L.1
Wales, R.2
Richardson, P.T.3
-
89
-
-
0028330184
-
Intracellular dynamics of ricin followed by fluorescence microscopy on living cells reveals a rapid accumulation of the dimeric toxin in the Golgi apparatus
-
Lendaro E, Ippoliti R, Bellelli A, et al. Intracellular dynamics of ricin followed by fluorescence microscopy on living cells reveals a rapid accumulation of the dimeric toxin in the Golgi apparatus. FEBS Lett 1994; 344: 99-104.
-
(1994)
FEBS Lett
, vol.344
, pp. 99-104
-
-
Lendaro, E.1
Ippoliti, R.2
Bellelli, A.3
-
90
-
-
0023878452
-
Estimation of the amount of internalized ricin that reaches the trans-Golgi network
-
van Deurs B, Sandvig K, Petersen OW, Olsnes S, Simons K, Griffiths G. Estimation of the amount of internalized ricin that reaches the trans-Golgi network. J Cell Biol 1988; 106: 253-267 (Pubitemid 18052176)
-
(1988)
Journal of Cell Biology
, vol.106
, Issue.2
, pp. 253-267
-
-
Van Deurs, B.1
Sandvig, K.2
Petersen, O.W.3
Olsnes, S.4
Simons, K.5
Griffiths, G.6
-
91
-
-
0032559646
-
Toxin entry: Retrograde transport through the secretory pathway
-
DOI 10.1083/jcb.140.4.733
-
Lord JM, Roberts LM. Toxin entry: retrograde transport through the secretory pathway. J Cell Biol 1998; 140: 733-736 (Pubitemid 28141213)
-
(1998)
Journal of Cell Biology
, vol.140
, Issue.4
, pp. 733-736
-
-
Lord, J.M.1
Roberts, L.M.2
-
92
-
-
4644221489
-
Ricin: The endoplasmic reticulum connection
-
Roberts L. M., Smith D. C. Ricin: the endoplasmic reticulum connection Toxicon 2004; 44: 469-472
-
(2004)
Toxicon
, vol.44
, pp. 469-472
-
-
Roberts, L.M.1
Smith, D.C.2
-
94
-
-
0025764613
-
Recycling of proteins between the endoplasmic reticulum and Golgi complex
-
Pelham HR. Recycling of proteins between the endoplasmic reticulum and Golgi complex. Curr Opin Cell Biol 1991; 3: 585-591 (Pubitemid 121006115)
-
(1991)
Current Opinion in Cell Biology
, vol.3
, Issue.4
, pp. 585-591
-
-
Pelham, H.R.B.1
-
95
-
-
0030450784
-
The dynamic organisation of the secretory pathway
-
Pelham HR. The dynamic organisation of the secretory pathway. Cell Struct Funct 1996; 21: 413-419
-
(1996)
Cell Struct Funct
, vol.21
, pp. 413-419
-
-
Pelham, H.R.1
-
96
-
-
0026465205
-
Addition of an ER retention signal to the ricin a chain increases the cytotoxicity of the holotoxin
-
Wales R, Chaddock JA, Roberts LM, Lord JM. Addition of an ER retention signal to the ricin A chain increases the cytotoxicity of the holotoxin. Exp Cell Res 1992; 203: 1-4.
-
(1992)
Exp Cell Res
, vol.203
, pp. 1-4
-
-
Wales, R.1
Chaddock, J.A.2
Roberts, L.M.3
Lord, J.M.4
-
97
-
-
0027484154
-
Addition of an endoplasmic reticulum retrieval sequence to ricin a chain significantly increases its cytotoxicity to mammalian cells
-
Wales R, Roberts LM, Lord JM. Addition of an endoplasmic reticulum retrieval sequence to ricin A chain significantly increases its cytotoxicity to mammalian cells. J Biol Chem 1993; 268: 23986-23990 (Pubitemid 23335376)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.32
, pp. 23986-23990
-
-
Wales, R.1
Roberts, L.M.2
Lord, J.M.3
-
98
-
-
0035831558
-
An Interaction between Ricin and Calreticulin That May Have Implications for Toxin Trafficking
-
DOI 10.1074/jbc.M009499200
-
Day PJ, Owens SR, Wesche J, Olsnes S, Roberts LM, Lord JM. An interaction between ricin and calreticulin that may have implications for toxin trafficking. J Biol Chem 2001; 276: 7202-7208 (Pubitemid 37392023)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.10
, pp. 7202-7208
-
-
Day, P.J.1
Owens, S.R.2
Wesche, J.3
Olsnes, S.4
Roberts, L.M.5
Lord, J.M.6
-
99
-
-
0033607688
-
Dependence of ricin toxicity on translocation of the toxin A-chain from the endoplasmic reticulum to the cytosol
-
Wesche J, Rapak A, Olsnes S. Dependence of ricin toxicity on translocation of the toxin A-chain from the endoplasmic reticulum to the cytosol. J Biol Chem 1999; 274: 34443-34449
-
(1999)
J Biol Chem
, vol.274
, pp. 34443-34449
-
-
Wesche, J.1
Rapak, A.2
Olsnes, S.3
-
100
-
-
56249144175
-
Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum
-
Spooner RA, Hart PJ, Cook JP, et al. Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum. Proc Natl Acad Sci USA 2008; 105: 17408-17413
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 17408-17413
-
-
Spooner, R.A.1
Hart, P.J.2
Cook, J.P.3
-
101
-
-
0034737432
-
Ribosome-mediated folding of partially unfolded ricin A-chain
-
Argent RH, Parrott AM, Day PJ, et al. Ribosome-mediated folding of partially unfolded ricin A-chain. J Biol Chem 2000; 275: 9263-9269
-
(2000)
J Biol Chem
, vol.275
, pp. 9263-9269
-
-
Argent, R.H.1
Parrott, A.M.2
Day, P.J.3
-
102
-
-
0037066109
-
The low lysine content of ricin a chain reduces the risk of proteolytic degradation after translocation from the endoplasmic reticulum to the cytosol
-
Deeks ED, Cook JP, Day PJ, Smith DC, Roberts LM, Lord JM. The low lysine content of ricin A chain reduces the risk of proteolytic degradation after translocation from the endoplasmic reticulum to the cytosol. Biochemistry 2002; 41: 3405-3413
-
(2002)
Biochemistry
, vol.41
, pp. 3405-3413
-
-
Deeks, E.D.1
Cook, J.P.2
Day, P.J.3
Smith, D.C.4
Roberts, L.M.5
Lord, J.M.6
-
103
-
-
0025006266
-
The amino acid sequence of a ribosome-inactivating protein from Saponaria officinalis seeds
-
Maras B, Ippoliti R, De Luca E, et al. The amino acid sequence of a ribosome-inactivating protein from Saponaria officinalis seeds. Biochem Int 1990; 21: 831-838
-
(1990)
Biochem Int
, vol.21
, pp. 831-838
-
-
Maras, B.1
Ippoliti, R.2
De Luca, E.3
-
104
-
-
0023733039
-
Ribosome-inactivating proteins from plants inhibit ribosome activity of Trypanosoma and Leishmania
-
Cenini P, Bolognesi A, Stirpe F. Ribosome-inactivating proteins from plants inhibit ribosome activity of Trypanosoma and Leishmania. J Protozool 1988; 35: 384-387
-
(1988)
J Protozool
, vol.35
, pp. 384-387
-
-
Cenini, P.1
Bolognesi, A.2
Stirpe, F.3
-
105
-
-
0026042479
-
Effects of plant ribosomein-activating proteins on ribosomes from Musca domestica
-
Ferrari C, Barbieri L, Stirpe F. Effects of plant ribosomein-activating proteins on ribosomes from Musca domestica. Comp Biochem Physiol B 1991; 100: 223-227
-
(1991)
Comp Biochem Physiol B
, vol.100
, pp. 223-227
-
-
Ferrari, C.1
Barbieri, L.2
Stirpe, F.3
-
106
-
-
0026747806
-
High sensitivity of cultured human trophoblasts to ribosome-inactivating proteins
-
Battelli MG, Montacuti V, Stirpe F. High sensitivity of cultured human trophoblasts to ribosome-inactivating proteins. Exp Cell Res 1992; 201: 109-112
-
(1992)
Exp Cell Res
, vol.201
, pp. 109-112
-
-
Battelli, M.G.1
Montacuti, V.2
Stirpe, F.3
-
107
-
-
0026660286
-
Some ribosome-inactivating proteins depurinate ribosomal RNA at multiple sites
-
Barbieri L, Ferreras JM, Barraco A, Ricci P, Stirpe F. Some ribosome-inactivating proteins depurinate ribosomal RNA at multiple sites. Biochem J 1992; 286: 1-4.
-
(1992)
Biochem J
, vol.286
, pp. 1-4
-
-
Barbieri, L.1
Ferreras, J.M.2
Barraco, A.3
Ricci, P.4
Stirpe, F.5
-
108
-
-
0028977913
-
Alpha 2-macroglobulin receptor mediates binding and cytotoxicity of plant ribosome-inactivating proteins
-
Cavallaro U, Nykjaer A, Nielsen M, Soria MR. Alpha 2-macroglobulin receptor mediates binding and cytotoxicity of plant ribosome-inactivating proteins. Eur J Biochem 1995; 232: 165-171
-
(1995)
Eur J Biochem
, vol.232
, pp. 165-171
-
-
Cavallaro, U.1
Nykjaer, A.2
Nielsen, M.3
Soria, M.R.4
-
109
-
-
0030906147
-
Characterization of a saporin isoform with lower ribosome-inhibiting activity
-
Fabbrini MS, Rappocciolo E, Carpani D, et al. Characterization of a saporin isoform with lower ribosome-inhibiting activity. Biochem J 1997; 322: 719-727 (Pubitemid 27135616)
-
(1997)
Biochemical Journal
, vol.322
, Issue.3
, pp. 719-727
-
-
Fabbrini, M.S.1
Rappocciolo, E.2
Carpani, D.3
Solinas, M.4
Valsasina, B.5
Breme, U.6
Cavallaro, U.7
Nykjaer, A.8
Rovida, E.9
Legname, G.10
Soria, M.R.11
-
112
-
-
0026573883
-
Antitumor activity of basic fibroblast growth factor-saporin mitotoxin in vitro and in vivo
-
Beitz JG, Davol P, Clark JW, et al. Antitumor activity of basic fibroblast growth factor-saporin mitotoxin in vitro and in vivo. Cancer Res 1992; 52: 227-230
-
(1992)
Cancer Res
, vol.52
, pp. 227-230
-
-
Beitz, J.G.1
Davol, P.2
Clark, J.W.3
-
113
-
-
0026604298
-
Basic fibroblast growth factor in cells derived from Dupuytren's contracture: Synthesis, presence, and implications for treatment of the disease
-
Lappi DA, Martineau D, Maher PA, et al. Basic fibroblast growth factor in cells derived from Dupuytren's contracture: synthesis, presence, and implications for treatment of the disease. J Hand Surg Am 1992; 17: 324-332
-
(1992)
J Hand Surg Am
, vol.17
, pp. 324-332
-
-
Lappi, D.A.1
Martineau, D.2
Maher, P.A.3
-
114
-
-
0027320237
-
Reducing the heterogeneity of chemically conjugated targeted toxins: Homogeneous basic FGF-saporin
-
DOI 10.1006/abio.1993.1353
-
Lappi DA, Matsunami R, Martineau D, Baird A. Reducing the heterogeneity of chemically conjugated targeted toxins: homogeneous basic FGF-saporin. Anal Biochem 1993; 212: 446-451 (Pubitemid 23245096)
-
(1993)
Analytical Biochemistry
, vol.212
, Issue.2
, pp. 446-451
-
-
Lappi, D.A.1
Matsunami, R.2
Martineau, D.3
Baird, A.4
-
115
-
-
0028270899
-
Expression and activities of a recombinant basic fibroblast growth factor-saporin fusion protein
-
Lappi DA, Ying W, Barthelemy I, et al. Expression and activities of a recombinant basic fibroblast growth factor-saporin fusion protein. J Biol Chem 1994; 269: 12552-12558 (Pubitemid 24982277)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.17
, pp. 12552-12558
-
-
Lappi, D.A.1
Ying, W.2
Barthelemy, I.3
Martineau, D.4
Prieto, I.5
Benatti, L.6
Soria, M.7
Baird, A.8
-
116
-
-
0029616001
-
Synthesis and characterization of a homogeneous chemical conjugate between basic fibroblast growth factor and saporin
-
Buechler YJ, Sosnowski BA, Victor KD, et al. Synthesis and characterization of a homogeneous chemical conjugate between basic fibroblast growth factor and saporin. Eur J Biochem 1995; 234: 706-713
-
(1995)
Eur J Biochem
, vol.234
, pp. 706-713
-
-
Buechler, Y.J.1
Sosnowski, B.A.2
Victor, K.D.3
-
117
-
-
0029123596
-
A chimeric saporintransferrin conjugate compared to ricin toxin: Role of the carrier in intracellular transport and toxicity
-
Ippoliti R, Lendaro E, D'Agostino I, et al. A chimeric saporintransferrin conjugate compared to ricin toxin: role of the carrier in intracellular transport and toxicity. FASEB J 1995; 9: 1220-1225
-
(1995)
FASEB J
, vol.9
, pp. 1220-1225
-
-
Ippoliti, R.1
Lendaro, E.2
D'Agostino, I.3
-
118
-
-
0029738732
-
The mitotoxin, basic fibroblast growth factor-saporin, effectively targets human prostatic carcinoma in an animal model
-
Davol P, Frackelton AR Jr. The mitotoxin, basic fibroblast growth factor-saporin, effectively targets human prostatic carcinoma in an animal model. J Urol 1996; 156: 1174-1179 (Pubitemid 26269851)
-
(1996)
Journal of Urology
, vol.156
, Issue.3
, pp. 1174-1179
-
-
Davol, P.1
Frackelton Jr., A.R.2
-
119
-
-
0030162264
-
Antiproliferative effect of basic fibroblast growth factorsaporin mitotoxin on keratocytes in culture
-
Wee WR, Parandoosh Z, Sakamoto T, Caton M, Nova M, McDonnell PJ. Antiproliferative effect of basic fibroblast growth factorsaporin mitotoxin on keratocytes in culture. Korean J Ophthalmol 1996; 10: 1-7.
-
(1996)
Korean J Ophthalmol
, vol.10
, pp. 1-7
-
-
Wee, W.R.1
Parandoosh, Z.2
Sakamoto, T.3
Caton, M.4
Nova, M.5
McDonnell, P.J.6
-
120
-
-
0030777549
-
The amino-terminal fragment of human urokinase directs a recombinant chimeric toxin to target cells: Internalization is toxin mediated
-
Fabbrini MS, Carpani D, Bello-Rivero I, Soria MR. The amino-terminal fragment of human urokinase directs a recombinant chimeric toxin to target cells: internalization is toxin mediated. FASEB J 1997; 11: 1169-1176 (Pubitemid 27481441)
-
(1997)
FASEB Journal
, vol.11
, Issue.13
, pp. 1169-1176
-
-
Fabbrini, M.S.1
Carpani, D.2
Bello-Rivero, I.3
Soria, M.R.4
-
121
-
-
0031849597
-
Targeting tumor cells via EGF receptors: Selective toxicity of an HBEGF-toxin fusion protein
-
Chandler LA, Sosnowski BA, McDonald JR, et al. Targeting tumor cells via EGF receptors: selective toxicity of an HBEGF-toxin fusion protein. Int J Cancer 1998; 78: 106-111
-
(1998)
Int J Cancer
, vol.78
, pp. 106-111
-
-
Chandler, L.A.1
Sosnowski, B.A.2
McDonald, J.R.3
-
122
-
-
0033932611
-
Endocytosis of a chimera between human pro-urokinase and the plant toxin saporin: An unusual internalization mechanism
-
Ippoliti R, Lendaro E, Benedetti PA, et al. Endocytosis of a chimera between human pro-urokinase and the plant toxin saporin: an unusual internalization mechanism. FASEB J 2000; 14: 1335-1344 (Pubitemid 30439742)
-
(2000)
FASEB Journal
, vol.14
, Issue.10
, pp. 1335-1344
-
-
Ippoliti, R.1
Lendaro, E.2
Benedetti, P.A.3
Torrisi, M.R.4
Belleudi, F.5
Carpani, D.6
Soria, M.R.7
Fabbrini, M.S.8
-
123
-
-
0027371837
-
A conjugate between human urokinase and saporin, a type-1 ribosome- Inactivating protein, is selectively cytotoxic to urokinase receptor- expressing cells
-
Cavallaro U, del Vecchio A, Lappi DA, Soria MR. A conjugate between human urokinase and saporin, a type-1 ribosomein-activating protein, is selectively cytotoxic to urokinase receptorexpressing cells. J Biol Chem 1993; 268: 23186-23190 (Pubitemid 23328032)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.31
, pp. 23186-23190
-
-
Cavallaro, U.1
Del Vecchio, A.2
Lappi, D.A.3
Soria, M.R.4
-
124
-
-
0345700843
-
Cytotoxicity of ribosomeinactivating protein saporin is not mediated through α2-macroglobulin receptor
-
Baggaa S, Hosurb MV, Batraa JK. Cytotoxicity of ribosomeinactivating protein saporin is not mediated through α2-macroglobulin receptor. FEBS Lett 2003; 541: 16-20.
-
(2003)
FEBS Lett
, vol.541
, pp. 16-20
-
-
Baggaa, S.1
Hosurb, M.V.2
Batraa, J.K.3
-
125
-
-
33344459356
-
Photochemically stimulated drug delivery increases the cytotoxicity and specificity of EGF-saporin
-
DOI 10.1016/j.jconrel.2005.12.002, PII S0168365905007005
-
Weyergang A, Selbo PK, Berg K. Photochemically stimulated drug delivery increases the cytotoxicity and specificity of EGF-saporin. J Control Release 2006; 111: 165-173 (Pubitemid 43290005)
-
(2006)
Journal of Controlled Release
, vol.111
, Issue.1-2
, pp. 165-173
-
-
Weyergang, A.1
Selbo, P.K.2
Berg, K.3
-
126
-
-
34247371925
-
Targeted delivery and enhanced cytotoxicity of cetuximab-saporin by photochemical internalization in EGFR-positive cancer cells
-
DOI 10.1021/mp060105u
-
Yip WL, Weyergang A, Berg K, Tønnesen HH, Selbo PK. Targeted delivery and enhanced cytotoxicity of cetuximab-saporin by photochemical internalization in EGFR-positive cancer cells. Mol Pharm 2007; 4: 241-251 (Pubitemid 46640600)
-
(2007)
Molecular Pharmaceutics
, vol.4
, Issue.2
, pp. 241-251
-
-
Wai, L.Y.1
Weyergang, A.2
Berg, K.3
Tonnesen, H.H.4
Selbo, P.K.5
-
127
-
-
51849151811
-
Enhanced cytotoxicity of saporin by polyamidoamine dendrimer conjugation and photochemical internalization
-
Lai PS, Pai CL, Peng CL, Shieh MJ, Berg K, Lou PJ. Enhanced cytotoxicity of saporin by polyamidoamine dendrimer conjugation and photochemical internalization. J Biomed Mater Res A 2008; 87: 147-155
-
(2008)
J Biomed Mater Res A
, vol.87
, pp. 147-155
-
-
Lai, P.S.1
Pai, C.L.2
Peng, C.L.3
Shieh, M.J.4
Berg, K.5
Lou, P.J.6
-
128
-
-
0031670368
-
The effect of monensin and chloroquine on the endocytosis and toxicity of chimeric toxins
-
DOI 10.1007/s000180050214
-
Ippoliti R, Ginobbi P, Lendaro E, et al. The effect of monensin and chloroquine on the endocytosis and toxicity of chimeric toxins. Cell Mol Life Sci 1998; 54: 866-875 (Pubitemid 28425317)
-
(1998)
Cellular and Molecular Life Sciences
, vol.54
, Issue.8
, pp. 866-875
-
-
Ippoliti, R.1
Ginobbi, P.2
Lendaro, E.3
D'Agostino, I.4
Ombres, D.5
Benedetti, P.A.6
Brunori, M.7
Citro, G.8
-
129
-
-
34548444675
-
Lipopolyamine treatment increases the efficacy of intoxication with saporin and an anticancer saporin conjugate
-
DOI 10.1111/j.1742-4658.2007.06008.x
-
Geden SE, Gardner RA, Fabbrini MS, Ohashi M, Phanstiel Iv O, Teter K. Lipopolyamine treatment increases the efficacy of intoxication with saporin and an anticancer saporin conjugate. FEBS J 2007; 274: 4825-4836 (Pubitemid 47353132)
-
(2007)
FEBS Journal
, vol.274
, Issue.18
, pp. 4825-4836
-
-
Geden, S.E.1
Gardner, R.A.2
Fabbrini, M.S.3
Ohashi, M.4
Phanstiel IV, O.5
Teter, K.6
-
130
-
-
70249091403
-
Enhancement of saporin cytotoxicity by Gypsophila saponins-More than stimulation of endocytosis
-
doi:10.1016/j.cbi.2009.07.007
-
Weng A, Bachran C, Fuchs H, Krause E, Stephanowitz H, Melzig MF. Enhancement of saporin cytotoxicity by Gypsophila saponins-More than stimulation of endocytosis. Chem Biol Interact 2009; doi:10.1016/j.cbi.2009.07.007
-
(2009)
Chem Biol Interact
-
-
Weng, A.1
Bachran, C.2
Fuchs, H.3
Krause, E.4
Stephanowitz, H.5
Melzig, M.F.6
-
131
-
-
26244458686
-
Saporin and ricin a chain follow different intracellular routes to enter the cytosol of intoxicated cells
-
DOI 10.1111/j.1742-4658.2005.04908.x
-
Vago R, Marsden CJ, Lord JM, et al. Saporin and ricin A chain follow different intracellular routes to enter the cytosol of intoxicated cells. FEBS J 2005; 272: 4983-4995 (Pubitemid 41415121)
-
(2005)
FEBS Journal
, vol.272
, Issue.19
, pp. 4983-4995
-
-
Vago, R.1
Marsden, C.J.2
Lord, J.M.3
Ippoliti, R.4
Flavell, D.J.5
Flavell, S.-U.6
Ceriotti, A.7
Fabbrini, M.S.8
-
133
-
-
0026102824
-
Immunotoxins containing ricin or its a chain
-
Vitetta ES, Thorpe PE. Immunotoxins containing ricin or its A chain. Semin Cell Biol 1991; 2: 47-58.
-
(1991)
Semin Cell Biol
, vol.2
, pp. 47-58
-
-
Vitetta, E.S.1
Thorpe, P.E.2
-
134
-
-
67650678448
-
Humanized immunotoxins: A new generation of immunotoxins for targeted cancer therapy
-
Mathew M, Verma R S. Humanized immunotoxins: A new generation of immunotoxins for targeted cancer therapy. Cancer Sci 2009; 100: 1359-1365
-
(2009)
Cancer Sci
, vol.100
, pp. 1359-1365
-
-
Mathew, M.1
Verma, R.S.2
-
135
-
-
0024151011
-
Immunotoxins containing single-chain ribosome-inactivating proteins
-
Lambert JM, Blättler WA, McIntyre GD, Goldmacher VS, Scott CF Jr. Immunotoxins containing single-chain ribosome-inactivating proteins. Cancer Treat Res 1988; 3: 175-209.
-
(1988)
Cancer Treat Res
, vol.3
, pp. 175-209
-
-
Lambert, J.M.1
Blättler, W.A.2
McIntyre, G.D.3
Goldmacher, V.S.4
Scott Jr., C.F.5
-
136
-
-
33748309412
-
Immunotoxins for Targeted Cancer Therapy
-
Kreitman RJ. Immunotoxins for Targeted Cancer Therapy. AAPS J 2006; 8: 532-551
-
(2006)
AAPS J
, vol.8
, pp. 532-551
-
-
Kreitman, R.J.1
-
137
-
-
0025886113
-
Single-chain ribosome inactivating proteins from plants depurinate Escherichia coli 23S ribosomal RNA
-
Hartley MR, Legname G, Osborn R, Chen Z, Lord JM. Single-chain ribosome inactivating proteins from plants depurinate Escherichia coli 23S ribosomal RNA. FEBS Lett 1991; 290: 65-68
-
(1991)
FEBS Lett
, vol.290
, pp. 65-68
-
-
Hartley, M.R.1
Legname, G.2
Osborn, R.3
Chen, Z.4
Lord, J.M.5
-
138
-
-
0023664423
-
Expression of ricin a chain in Escherichia coli
-
O'Hare M, Roberts LM, Thorpe PE, Watson GJ, Prior B, Lord JM. Expression of ricin A chain in Escherichia coli. FEBS Lett 1987; 216: 73-78
-
(1987)
FEBS Lett
, vol.216
, pp. 73-78
-
-
O'Hare, M.1
Roberts, L.M.2
Thorpe, P.E.3
Watson, G.J.4
Prior, B.5
Lord, J.M.6
-
139
-
-
0029420520
-
Heterologous expression, purification, activity and conformational studies of different forms of dianthin 30
-
Legname G, Fossati G, Monzini N, et al. Heterologous expression, purification, activity and conformational studies of different forms of dianthin 30. Biomed Pept Proteins Nucleic Acids 1995; 1: 61-68
-
(1995)
Biomed Pept Proteins Nucleic Acids
, vol.1
, pp. 61-68
-
-
Legname, G.1
Fossati, G.2
Monzini, N.3
-
140
-
-
0033950004
-
Cytosolic immunization allows the expression of preATF-saporin chimeric toxin in eukaryotic cells
-
Fabbrini MS, Carpani D, Soria MR, Ceriotti A. Cytosolic immunization allows the expression of preATF-saporin chimeric toxin in eukaryotic cells. FASEB J 2000; 14: 391-398 (Pubitemid 30086076)
-
(2000)
FASEB Journal
, vol.14
, Issue.2
, pp. 391-398
-
-
Fabbrini, M.S.1
Carpani, D.2
Soria, M.R.3
Ceriotti, A.4
-
141
-
-
58149129878
-
Development of antiricin single domain antibodies toward detection and therapeutic reagents
-
Anderson G P, Liu J L, Hale ML, et al. Development of antiricin single domain antibodies toward detection and therapeutic reagents. Anal Chem 2008; 80: 9604-9611
-
(2008)
Anal Chem
, vol.80
, pp. 9604-9611
-
-
Anderson, G.P.1
Liu, J.L.2
Hale, M.L.3
-
142
-
-
77951520474
-
Pichia pastoris as a host for the production of saporin containing chimaeras
-
in press
-
Lombardi A, Bursomanno S, Lopardo T, et al. Pichia pastoris as a host for the production of saporin containing chimaeras. FASEB J 2009; in press.
-
(2009)
FASEB J
-
-
Lombardi, A.1
Bursomanno, S.2
Lopardo, T.3
-
144
-
-
0033943074
-
Use of immunotoxins in the treatment of lymphoma
-
Sausville EA. Use of immunotoxins in the treatment of lymphoma. Cancer J 2000; 6: 135-138
-
(2000)
Cancer J
, vol.6
, pp. 135-138
-
-
Sausville, E.A.1
-
145
-
-
3142780741
-
The conjugate Rituximab/saporin-S6 completely inhibits clonogenic growth of CD20-expressing cells and produces a synergistic toxic effect with Fludarabine
-
DOI 10.1038/sj.leu.2403378
-
Polito L, Bolognesi A, Tazzari PL, et al. The conjugate Rituximab/saporin-S6 completely inhibits clonogenic growth of CD20-expressing cells and produces a synergistic toxic effect with Fludarabine. Leukemia 2004; 18: 1215-1222 (Pubitemid 39023131)
-
(2004)
Leukemia
, vol.18
, Issue.7
, pp. 1215-1222
-
-
Polito, L.1
Bolognesi, A.2
Tazzari, P.L.3
Farini, V.4
Lubelli, C.5
Zinzani, P.L.6
Ricci, F.7
Stirpe, F.8
-
146
-
-
0030728258
-
Systemic therapy with 3BIT, a triple combination cocktail of anti-CD19, -CD22, and -CD38-saporin immunotoxins, is curative of human B-cell lymphoma in severe combined immunodeficient mice
-
Flavell DJ, Noss A, Pulford KA, Ling N, Flavell SU. Systemic therapy with 3BIT, a triple combination cocktail of anti-CD19, -CD22, and -CD38-saporin immunotoxins, is curative of human Bcell lymphoma in severe combined immunodeficient mice. Cancer Res 1997; 57: 4824-4829 (Pubitemid 27468990)
-
(1997)
Cancer Research
, vol.57
, Issue.21
, pp. 4824-4829
-
-
Flavell, D.J.1
Noss, A.2
Pulford, K.A.F.3
Ling, N.4
Flavell, S.U.5
-
147
-
-
33747229123
-
Ribosome-inactivating proteins: Progress and problems
-
Stirpe F, Battelli MG. Ribosome-inactivating proteins: progress and problems. Cell Mol Life Sci 2006; 63: 1850-1866
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 1850-1866
-
-
Stirpe, F.1
Battelli, M.G.2
-
148
-
-
0034255636
-
The effect of a monoclonal antibody coupled to ricin a chain-derived peptides on endothelial cells in vitro: Insights into toxin-mediated vascular damage
-
Baluna R, Coleman E, Jones C, Ghetie V, Vitetta ES. The effect of a monoclonal antibody coupled to ricin A chain-derived peptides on endothelial cells in vitro: insights into toxin-mediated vascular damage. Exp Cell Res 2000; 258: 417-424
-
(2000)
Exp Cell Res
, vol.258
, pp. 417-424
-
-
Baluna, R.1
Coleman, E.2
Jones, C.3
Ghetie, V.4
Vitetta, E.S.5
-
149
-
-
0035220125
-
In vitro studies of ricin A-chain-induced vascular leak syndrome
-
Lindstrom AL, Pennell CA. In vitro studies of ricin A-chain-induced vascular leak syndrome. Methods Mol Biol 2001; 166: 125-135
-
(2001)
Methods Mol Biol
, vol.166
, pp. 125-135
-
-
Lindstrom, A.L.1
Pennell, C.A.2
-
150
-
-
0037382907
-
Genetic engineering of an immunotoxin to eliminate pulmonary vascular leak in mice
-
DOI 10.1038/nbt800
-
Smallshaw JE, Ghetie V, Rizo J, et al. Genetic engineering of an immunotoxin to eliminate pulmonary vascular leak in mice. Nat Biotechnol 2003; 21: 387-391 (Pubitemid 36397658)
-
(2003)
Nature Biotechnology
, vol.21
, Issue.4
, pp. 387-391
-
-
Smallshaw, J.E.1
Ghetie, V.2
Rizo, J.3
Fulmer, J.R.4
Trahan, L.L.5
Ghetie, M.-A.6
Vitetta, E.S.7
-
151
-
-
0030968650
-
Characterization of vascular leak syndrome induced by the toxin component of Pseudomonas exotoxin-based immunotoxins and its potential inhibition with nonsteroidal anti-inflammatory drugs
-
Siegall CB, Liggitt D, Chace D, et al. Characterization of vascular leak syndrome induced by the toxin component of Pseudomonas exotoxin-based immunotoxins and its potential inhibition with non-steroidal anti-inflammatory drugs. Clin Cancer Res 1997; 3: 339-345 (Pubitemid 27158056)
-
(1997)
Clinical Cancer Research
, vol.3
, Issue.3
, pp. 339-345
-
-
Siegall, C.B.1
Liggitt, D.2
Chace, D.3
Mixan, B.4
Sugai, J.5
Davidson, T.6
Steinitz, M.7
-
152
-
-
0037427781
-
A cleavable adapter to reduce nonspecific cytotoxicity of recombinant immunotoxins
-
DOI 10.1002/ijc.10809
-
Heisler I, Keller J, Tauber R, Sutherland M, Fuchs H. A cleavable adapter to reduce nonspecific cytotoxicity of recombinant immunotoxins. Int J Cancer 2003; 103: 277-282 (Pubitemid 35461522)
-
(2003)
International Journal of Cancer
, vol.103
, Issue.2
, pp. 277-282
-
-
Heisler, I.1
Keller, J.2
Tauber, R.3
Sutherland, M.4
Fuchs, H.5
-
153
-
-
0023105708
-
Selective killing of human bladder cancer cells by combined treatment with a and B chain ricin antibody conjugates
-
Thiesen H-J, Juhl H, Arndt R. Selective killing of human bladder cancer cells by combined treatment with A and B chain ricin antibody conjugates. Cancer Res 1987; 47: 419-423 (Pubitemid 17009603)
-
(1987)
Cancer Research
, vol.47
, Issue.2
, pp. 419-423
-
-
Thiesen, H.-J.1
Juhl, H.2
Arndt, R.3
-
154
-
-
0029991101
-
Toxicity of ribosome-inactivating proteins-containing immunotoxins to a human bladder carcinoma cell line
-
DOI 10.1002/(SICI)1097-0215(19960208)65:4<485::AID-IJC16>3.0.CO;2-9
-
Battelli MG, Polito L, Bolognesi A, Lafleur L, Fradet Y, Stirpe F. Toxicity of ribosome-inactivating proteins containing immunotoxins to a human bladder carcinoma cell line. Int J Cancer 1996; 65: 485-490 (Pubitemid 26084402)
-
(1996)
International Journal of Cancer
, vol.65
, Issue.4
, pp. 485-490
-
-
Battelli, M.G.1
Polito, L.2
Bolognesi, A.3
Lafleur, L.4
Fradet, Y.5
Stirpe, F.6
-
155
-
-
0030761036
-
Effect of fibroblast growth factor saporin mitotoxins on human bladder cell lines
-
DOI 10.1023/A:1018443430904
-
Tetzke TA, Caton MC, Maher PA, Parandoosh Z. Effect of fibroblast growth factor saporin mitotoxins on human bladder cell lines. Clin Exp Metastasis 1997; 15: 620-629 (Pubitemid 27435743)
-
(1997)
Clinical and Experimental Metastasis
, vol.15
, Issue.6
, pp. 620-629
-
-
Tetzke, T.A.1
Caton, M.C.2
Maher, P.A.3
Parandoosh, Z.4
-
156
-
-
0031934343
-
Skeletal muscle-specific immunotoxin for the treatment of focal muscle spasm
-
Hott JS, Dalakas MC, Sung C, Hallett M, Youle RJ. Skeletal muscle-specific immunotoxin for the treatment of focal muscle spasm. Neurology 1998; 50: 485-491 (Pubitemid 28119794)
-
(1998)
Neurology
, vol.50
, Issue.2
, pp. 485-491
-
-
Hott, J.S.1
Dalakas, M.C.2
Sung, C.3
Hallett, M.4
Youle, R.J.5
-
157
-
-
32644474374
-
Novel immunotoxin: A fusion protein consisting of gelonin and an acetylcholine receptor fragment as a potential immunotherapeutic agent for the treatment of Myasthenia gravis
-
DOI 10.1016/j.pep.2005.08.029, PII S1046592805002871
-
Hossann M, Li Z, Shi Y, et al. Novel immunotoxin: a fusion protein consisting of gelonin and an acetylcholine receptor fragment as a potential immunotherapeutic agent for the treatment of myasthenia gravis. Protein Expr Purif 2006; 46: 73-84. (Pubitemid 43246998)
-
(2006)
Protein Expression and Purification
, vol.46
, Issue.1
, pp. 73-84
-
-
Hossann, M.1
Li, Z.2
Shi, Y.3
Kreilinger, U.4
Buttner, J.5
Vogel, P.D.6
Yuan, J.7
Wise, J.G.8
Trommer, W.E.9
-
158
-
-
3242795995
-
Myotoxic effects of the skeletal muscle-specific immunotoxin, ricin-mAb35, on orbicularis oculi muscle after eyelid injections in rabbits
-
Harrison AR, Skladzien S, Christiansen SP, McLoon LK. Myotoxic effects of the skeletal muscle-specific immunotoxin, ricin-mAb35, on orbicularis oculi muscle after eyelid injections in rabbits. Ophthalmol Plast Reconstr Surg 2004; 20: 312-316
-
(2004)
Ophthalmol Plast Reconstr Surg
, vol.20
, pp. 312-316
-
-
Harrison, A.R.1
Skladzien, S.2
Christiansen, S.P.3
McLoon, L.K.4
-
159
-
-
0033771011
-
Acute effects of the skeletal musclespecific immunotoxin ricin-mAb 35 on extraocular muscles of rabbits
-
Christiansen SP, Sandnas A, Prill R, Youle RJ, McLoon LK. Acute effects of the skeletal musclespecific immunotoxin ricin-mAb 35 on extraocular muscles of rabbits. Invest. Ophthalmol Vis Sci 2000; 41: 3402-3409
-
(2000)
Invest. Ophthalmol Vis Sci
, vol.41
, pp. 3402-3409
-
-
Christiansen, S.P.1
Sandnas, A.2
Prill, R.3
Youle, R.J.4
McLoon, L.K.5
-
160
-
-
0036190419
-
Long-term effects of ricin-mAb 35 on extraocular muscles of rabbits: Potential treatment for strabismus
-
Christiansen SP, Peterson D, To T, Youle R, McLoon L. Long-term effects of ricin-mAb 35 on extraocular muscles of rabbits: potential treatment for strabismus. Invest Ophthalmol Vis Sci 2002; 43: 679-685 (Pubitemid 34184484)
-
(2002)
Investigative Ophthalmology and Visual Science
, vol.43
, Issue.3
, pp. 679-685
-
-
Christiansen, S.P.1
Peterson, D.2
To, T.3
Youle, R.4
McLoon, L.5
-
161
-
-
0035996284
-
Selective lesions of rabbit extraocular muscles injected with the anti-AChR immunotoxin saporin-mAB 73
-
DOI 10.1076/ceyr.24.1.58.5430
-
Campos EC, Schiavi C, Bolognesi A, et al. Selective lesions of rabbit extraocular muscles injected with the anti-AChR immunotoxin saporin-mAb 73. Curr Eye Res 2002; 24: 58-65. (Pubitemid 34765363)
-
(2002)
Current Eye Research
, vol.24
, Issue.1
, pp. 58-65
-
-
Campos, E.C.1
Schiavi, C.2
Bolognesi, A.3
Bellusci, C.4
Lubelli, C.5
Duca, A.6
Polito, L.7
Poulas, K.8
Tzartos, S.J.9
Stirpe, F.10
-
162
-
-
12744278656
-
Construction of tumor-specific toxins using ubiquitin fusion technique
-
Tcherniuk SO, Chroboczek J, Balakirev MY. Construction of tumor-specific toxins using ubiquitin fusion technique. Mol Ther 2005; 11: 196-204.
-
(2005)
Mol Ther
, vol.11
, pp. 196-204
-
-
Tcherniuk, S.O.1
Chroboczek, J.2
Balakirev, M.Y.3
-
163
-
-
0034669853
-
Neuronal lesioning with axonally transported toxins
-
Wiley RG, Kline IV RH. Neuronal lesioning with axonally transported toxins. J Neurosci Methods 2000; 103: 73-82.
-
(2000)
J Neurosci Methods
, vol.103
, pp. 73-82
-
-
Wiley, R.G.1
Kline IV, R.H.2
-
164
-
-
0026005999
-
Immunolesioning: Selective destruction of neurons using immunotoxin to rat NGF receptor
-
Wiley RG, Oeltmann TN, Lappi DA. Immunolesioning: Selective destruction of neurons using immunotoxin to rat NGF receptor. Brain Res 1991; 562: 149-153
-
(1991)
Brain Res
, vol.562
, pp. 149-153
-
-
Wiley, R.G.1
Oeltmann, T.N.2
Lappi, D.A.3
-
166
-
-
67349140926
-
Neuropeptide Y Receptor-Expressing dorsal horn neurons: Role in nocifensive reflex responses to heat and formalin
-
Wiley RG, Lemons LL, Kline IV RH. Neuropeptide Y Receptor-Expressing dorsal horn neurons: role in nocifensive reflex responses to heat and formalin. Neuroscience 2009; 161: 139-147
-
(2009)
Neuroscience
, vol.161
, pp. 139-147
-
-
Wiley, R.G.1
Lemons, L.L.2
Kline IV, R.H.3
-
167
-
-
0036644191
-
Exogenous peptides delivered by ricin require processing by signal peptidase for transporter associated with antigen processing-independent MHC class I-restricted presentation
-
Smith DC, Gallimore A, Jones E, et al. Exogenous peptides delivered by ricin require processing by signal peptidase for transporter associated with antigen processing-independent MHC class Irestricted presentation. J Immunol 2002; 169: 99-107. (Pubitemid 34686125)
-
(2002)
Journal of Immunology
, vol.169
, Issue.1
, pp. 99-107
-
-
Smith, D.C.1
Gallimore, A.2
Jones, E.3
Roberts, B.4
Lord, J.M.5
Deeks, E.6
Cerundolo, V.7
Roberts, L.M.8
-
169
-
-
0346039294
-
Expression, Purification and Characterization of Ricin vectors used for exogenous antigen delivery into the MHC Class I presentation pathway
-
Smith DC, Marsden CJ, Lord JM, Roberts LM. Expression, Purification and Characterization of Ricin vectors used for exogenous antigen delivery into the MHC Class I presentation pathway. Biol Proced Online 2003; 5: 13-19.
-
(2003)
Biol Proced Online
, vol.5
, pp. 13-19
-
-
Smith, D.C.1
Marsden, C.J.2
Lord, J.M.3
Roberts, L.M.4
-
171
-
-
62149131329
-
Production and purification of immunologically active core protein p24 from HIV-1 fused to ricin toxin B subunit in E. coli
-
Donayre-Torres AJ, Esquivel-Soto E, Gutiérrez-Xicoténcatl Mde L, Esquivel-Guadarrama FR, Gómez-Lim MA. Production and purification of immunologically active core protein p24 from HIV-1 fused to ricin toxin B subunit in E. coli. Virol J 2009; 6: 17-28.
-
(2009)
Virol J
, vol.6
, pp. 17-28
-
-
Donayre-Torres, A.J.1
Esquivel-Soto, E.2
Gutiérrez-Xicoténcatl, M.L.3
Esquivel-Guadarrama, F.R.4
Gómez-Lim, M.A.5
-
172
-
-
33645467903
-
Ricin toxin B subunit enhancement of rotavirus NSP4 immunogenicity in mice
-
Choi NW, Estes MK, Langridge WH. Ricin toxin B subunit enhancement of rotavirus NSP4 immunogenicity in mice. Viral Immunol 2006; 19: 54-63.
-
(2006)
Viral Immunol
, vol.19
, pp. 54-63
-
-
Choi, N.W.1
Estes, M.K.2
Langridge, W.H.3
-
173
-
-
31644451506
-
Synthesis of a ricin toxin B subunit-rotavirus VP7 fusion protein in potato
-
Choi NW, Estes MK, Langridge WH. Synthesis of a ricin toxin B subunit-rotavirus VP7 fusion protein in potato. Mol Biotechnol 2006; 32: 117-128
-
(2006)
Mol Biotechnol
, vol.32
, pp. 117-128
-
-
Choi, N.W.1
Estes, M.K.2
Langridge, W.H.3
-
174
-
-
30744471419
-
Protein toxins: Intracellular trafficking for targeted therapy
-
DOI 10.1038/sj.gt.3302557, PII 3302557
-
Johannes L, Decaudin D. Protein toxins: intracellular trafficking for targeted therapy. Gene Ther 2005; 12: 1360-1368 (Pubitemid 43090385)
-
(2005)
Gene Therapy
, vol.12
, Issue.18
, pp. 1360-1368
-
-
Johannes, L.1
Decaudin, D.2
-
175
-
-
33646569995
-
The Shiga toxin B-subunit targets antigen in vivo to dendritic cells and elicits anti-tumor immunity
-
Vingert B, Adotevi O, Patin D, et al. The Shiga toxin B-subunit targets antigen in vivo to dendritic cells and elicits anti-tumor immunity. Eur J Immunol 2006; 36: 1124-1135
-
(2006)
Eur J Immunol
, vol.36
, pp. 1124-1135
-
-
Vingert, B.1
Adotevi, O.2
Patin, D.3
-
176
-
-
38049021296
-
B subunit of Shiga toxin-based vaccines synergize with alpha-galactosylceramide to break tolerance against self antigen and elicit antiviral immunity
-
Adotevi O, Vingert B, Freyburger L, et al. B subunit of Shiga toxin-based vaccines synergize with alpha-galactosylceramide to break tolerance against self antigen and elicit antiviral immunity. J Immunol 2007; 179: 3371-3379
-
(2007)
J Immunol
, vol.179
, pp. 3371-3379
-
-
Adotevi, O.1
Vingert, B.2
Freyburger, L.3
-
177
-
-
33846238540
-
Saporin as a novel suicide gene in anticancer gene therapy
-
DOI 10.1038/sj.cgt.7700998, PII 7700998
-
Zarovni N, Vago R, Soldà T, Monaco L, Fabbrini MS. Saporin as a novel suicide gene in anticancer gene therapy. Cancer Gene Ther 2007; 14: 165-173 (Pubitemid 46106961)
-
(2007)
Cancer Gene Therapy
, vol.14
, Issue.2
, pp. 165-173
-
-
Zarovni, N.1
Vago, R.2
Solda, T.3
Monaco, L.4
Fabbrini, M.S.5
-
179
-
-
20344383266
-
An alternative strategy for sustainable pest resistance in genetically enhanced crops
-
DOI 10.1073/pnas.0502871102
-
Mehlo L, Gahakwa D, Nghia PT, et al. An alternative strategy for sustainable pest resistance in genetically enhanced crops. Proc Natl Acad Sci USA 2005; 102: 7812-7816 (Pubitemid 40781020)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.22
, pp. 7812-7816
-
-
Mehlo, L.1
Gahakwa, D.2
Nghia, P.T.3
Loc, N.T.4
Capell, T.5
Gatehouse, J.A.6
Gatehouse, A.M.R.7
Christou, P.8
|