Reductive activation of ricin and ricin A-chain immunotoxins by protein disulfide isomerase and thioredoxin reductase

Biochemical Pharmacology

Volumn 67, Issue 9, 2004, Pages 1721-1731

  Bellisola, Giuseppe ^a   Fracasso, Giulio ^a   Ippoliti, Rodolfo ^b   Menestrina, Gianfranco ^c   Rosén, Anders ^d   Soldà, Silvia ^a   Udali, Silvia ^a   Tomazzolli, Rossella ^c   Tridente, Giuseppe ^a   Colombatti, Marco ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b UNIVERSITY OF L'AQUILA   (Italy)

^c CNR   (Italy)

^d LINKÖPING UNIVERSITY   (Sweden)

Author keywords

mercaptoethanol; MET; Auranofin; Cholera toxin; CT; Diphteria toxin; Dithiothreitol; DT; DTT; ECL; Endoplasmic reticulum; Enhanced chemiluminescence; ER; GSH; S triethylphosphine gold(I) 2,3,4,6 tetra O acetyl 1 thio D glucopyranoside

Indexed keywords

AURANOFIN; CELL EXTRACT; DISULFIDE; GLUTATHIONE; GOLD DERIVATIVE; IMMUNOTOXIN; PROTEIN DISULFIDE ISOMERASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; RICIN; RICIN A; THIOREDOXIN; THIOREDOXIN REDUCTASE;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; ENZYMATIC ASSAY; HISTIOCYTIC LYMPHOMA; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LYMPHATIC LEUKEMIA; MICROSOME MEMBRANE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROSTATE CARCINOMA; T CELL LEUKEMIA;

AURANOFIN; HUMANS; IMMUNOTOXINS; NADP; OXIDATION-REDUCTION; PROTEIN DISULFIDE-ISOMERASE; RICIN; THIOREDOXIN REDUCTASE (NADPH); U937 CELLS;

EID: 11144357038     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.01.013     Document Type: Article

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