메뉴 건너뛰기




Volumn 103, Issue 2, 2003, Pages 277-282

A cleavable adapter to reduce nonspecific cytotoxicity of recombinant immunotoxins

Author keywords

Cleavable adapter; Epidermal growth factor; Immunotoxins; Saporin

Indexed keywords

ADENINE; BACTERIAL TOXIN; COMPLEMENTARY DNA; CYTOSOLIC CLEAVABLE PEPTIDE; DIPHTHERIA TOXIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; HYBRID PROTEIN; IMMUNOTOXIN; PEPTIDE; PLASMID DNA; PSEUDOMONAS EXOTOXIN; RECOMBINANT IMMUNOTOXIN; SAPORIN; UNCLASSIFIED DRUG;

EID: 0037427781     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10809     Document Type: Article
Times cited : (46)

References (26)
  • 2
    • 0035954240 scopus 로고    scopus 로고
    • Sensitivity of cancer cell lines to the novel non-toxic type 2 ribosome-inactivating protein nigrin b
    • Munoz R, Arias Y, Ferreras JM, Jimenez P, Rojo MA, Girbes T. Sensitivity of cancer cell lines to the novel non-toxic type 2 ribosome-inactivating protein nigrin b. Cancer Lett 2001;167:163-9.
    • (2001) Cancer Lett , vol.167 , pp. 163-169
    • Munoz, R.1    Arias, Y.2    Ferreras, J.M.3    Jimenez, P.4    Rojo, M.A.5    Girbes, T.6
  • 3
    • 0034109338 scopus 로고    scopus 로고
    • Recombinant antibody fragments and immunotoxin fusions for cancer therapy
    • Brinkmann U. Recombinant antibody fragments and immunotoxin fusions for cancer therapy. In Vivo 2000;14:21-7.
    • (2000) In Vivo , vol.14 , pp. 21-27
    • Brinkmann, U.1
  • 5
    • 0034151778 scopus 로고    scopus 로고
    • Human breast carcinoma cells express type II IL-4 receptors and are sensitive to antitumor activity of a chimeric IL-4-Pseudomonas exotoxin fusion protein in vitro and in vivo
    • Leland P, Taguchi J, Husain SR, Kreitman RJ, Pastan I, Puri RK. Human breast carcinoma cells express type II IL-4 receptors and are sensitive to antitumor activity of a chimeric IL-4-Pseudomonas exotoxin fusion protein in vitro and in vivo. Mol Med 2000;6:165-78.
    • (2000) Mol Med , vol.6 , pp. 165-178
    • Leland, P.1    Taguchi, J.2    Husain, S.R.3    Kreitman, R.J.4    Pastan, I.5    Puri, R.K.6
  • 6
    • 0033162598 scopus 로고    scopus 로고
    • FDA approves fusion protein for treatment of lymphoma
    • Piascik P. FDA approves fusion protein for treatment of lymphoma. J Am Pharm Assoc (Wash) 1999;39:571-2.
    • (1999) J Am Pharm Assoc (Wash) , vol.39 , pp. 571-572
    • Piascik, P.1
  • 7
    • 0033800221 scopus 로고    scopus 로고
    • Drug targeting
    • Torchilin VP. Drug targeting. Eur J Pharm Sci 2000;11 (Suppl 2): S81-91.
    • (2000) Eur J Pharm Sci , vol.11 , Issue.SUPPL. 2
    • Torchilin, V.P.1
  • 8
    • 0034821591 scopus 로고    scopus 로고
    • Chimeric fusion proteins - Pseudomonas exotoxinbased
    • Kreitman RJ. Chimeric fusion proteins - Pseudomonas exotoxinbased. Curr Opin Investig Drugs 2001;2:1282-93.
    • (2001) Curr Opin Investig Drugs , vol.2 , pp. 1282-1293
    • Kreitman, R.J.1
  • 9
    • 0033925354 scopus 로고    scopus 로고
    • Immunotoxins and vascular leak syndrome
    • Vitetta ES. Immunotoxins and vascular leak syndrome. Cancer J Sci Am 2000;6 (Suppl 3):S218-24.
    • (2000) Cancer J Sci Am , vol.6 , Issue.SUPPL. 3
    • Vitetta, E.S.1
  • 10
    • 0035394359 scopus 로고    scopus 로고
    • Lowering the isoelectric point of the Fv portion of recombinant immunotoxins leads to decreased nonspecific animal toxicity without affecting antitumor activity
    • Onda M, Nagata S, Tsutsumi Y, Vincent JJ, Wang Q, Kreitman RJ, Lee B, Pastan I. Lowering the isoelectric point of the Fv portion of recombinant immunotoxins leads to decreased nonspecific animal toxicity without affecting antitumor activity. Cancer Res 2001;61:5070-7.
    • (2001) Cancer Res , vol.61 , pp. 5070-5077
    • Onda, M.1    Nagata, S.2    Tsutsumi, Y.3    Vincent, J.J.4    Wang, Q.5    Kreitman, R.J.6    Lee, B.7    Pastan, I.8
  • 11
    • 0028304478 scopus 로고
    • Cleavage of pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver
    • Chiron MF, Fryling CM, FitzGerald DJ. Cleavage of pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver. J Biol Chem 1994;269:18167-76.
    • (1994) J Biol Chem , vol.269 , pp. 18167-18176
    • Chiron, M.F.1    Fryling, C.M.2    FitzGerald, D.J.3
  • 12
    • 0025012987 scopus 로고
    • Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity
    • Chaudhary VK, Jinno Y, FitzGerald D, Pastan I. Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity. Proc Natl Acad Sci USA 1990;87:308-12.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 308-312
    • Chaudhary, V.K.1    Jinno, Y.2    FitzGerald, D.3    Pastan, I.4
  • 14
    • 0034119870 scopus 로고    scopus 로고
    • Apoptosis induced by immunotoxins used in the treatment of hematologic malignancies
    • Keppler-Hatkemeyer A, Kreitman RJ, Pastan I. Apoptosis induced by immunotoxins used in the treatment of hematologic malignancies. Int J Cancer 2000;87:86-94.
    • (2000) Int J Cancer , vol.87 , pp. 86-94
    • Keppler-Hatkemeyer, A.1    Kreitman, R.J.2    Pastan, I.3
  • 15
    • 0035816182 scopus 로고    scopus 로고
    • Development of a novel molecular adapter for the optimization of immunotoxins
    • Keller J, Heisler I, Tauber R, Fuchs H. Development of a novel molecular adapter for the optimization of immunotoxins. J Control Release 2001;74:259-61.
    • (2001) J Control Release , vol.74 , pp. 259-261
    • Keller, J.1    Heisler, I.2    Tauber, R.3    Fuchs, H.4
  • 16
    • 0034021679 scopus 로고    scopus 로고
    • Novel cell permeable motif derived from the PreS2-domain of hepatitis-B virus surface antigens
    • Oess S, Hildt E. Novel cell permeable motif derived from the PreS2-domain of hepatitis-B virus surface antigens. Gene Ther 2000;7:750-8.
    • (2000) Gene Ther , vol.7 , pp. 750-758
    • Oess, S.1    Hildt, E.2
  • 17
    • 0036499268 scopus 로고    scopus 로고
    • A colorimetric assay for the quantitation of free adenine applied to determine the enzymatic activity of ribosome-inactivating proteins
    • Heisler I, Keller J, Tauber R, Sutherland M, Fuchs H. A colorimetric assay for the quantitation of free adenine applied to determine the enzymatic activity of ribosome-inactivating proteins. Anal Biochem 2002;302:114-22.
    • (2002) Anal Biochem , vol.302 , pp. 114-122
    • Heisler, I.1    Keller, J.2    Tauber, R.3    Sutherland, M.4    Fuchs, H.5
  • 19
    • 0029037003 scopus 로고
    • Proteolysis prevents in vivo chimeric fusion protein import into yeast mitochondria. Cytosolic cleavage and subcellular distribution
    • Zhou J, Bai Y, Weiner H. Proteolysis prevents in vivo chimeric fusion protein import into yeast mitochondria. Cytosolic cleavage and subcellular distribution. J Biol Chem 1995;270:16689-93.
    • (1995) J Biol Chem , vol.270 , pp. 16689-16693
    • Zhou, J.1    Bai, Y.2    Weiner, H.3
  • 20
    • 0028977913 scopus 로고
    • Alpha 2-macroglobulin receptor mediates binding and cytotoxicity of plant ribosome-inactivating proteins
    • Cavallaro U, Nykjaer A, Nielsen M, Soria MR. Alpha 2-macroglobulin receptor mediates binding and cytotoxicity of plant ribosome-inactivating proteins. Eur J Biochem 1995;232:165-71.
    • (1995) Eur J Biochem , vol.232 , pp. 165-171
    • Cavallaro, U.1    Nykjaer, A.2    Nielsen, M.3    Soria, M.R.4
  • 21
    • 0031573069 scopus 로고    scopus 로고
    • Prevention of immunotoxin-induced immunogenicity by coadministration with CTLA4Ig enhances antitumor efficacy
    • Siegall CB, Haggerty HG, Warner GL, Chace D, Mixan B, Linsley PS, Davidson T. Prevention of immunotoxin-induced immunogenicity by coadministration with CTLA4Ig enhances antitumor efficacy. J Immunol 1997;159:5168-73.
    • (1997) J Immunol , vol.159 , pp. 5168-5173
    • Siegall, C.B.1    Haggerty, H.G.2    Warner, G.L.3    Chace, D.4    Mixan, B.5    Linsley, P.S.6    Davidson, T.7
  • 22
    • 0035117041 scopus 로고    scopus 로고
    • Loss of caspase-1 and caspase-3 protein expression in human prostate cancer
    • Winter RN, Kramer A, Borkowski A, Kyprianou N. Loss of caspase-1 and caspase-3 protein expression in human prostate cancer. Cancer Res 2001;61:1227-32.
    • (2001) Cancer Res , vol.61 , pp. 1227-1232
    • Winter, R.N.1    Kramer, A.2    Borkowski, A.3    Kyprianou, N.4
  • 23
    • 0022411726 scopus 로고
    • Regulation of protein breakdown by epidermal growth factor in A431 cells
    • Ballard FJ. Regulation of protein breakdown by epidermal growth factor in A431 cells. Exp Cell Res 1985;157:172-80.
    • (1985) Exp Cell Res , vol.157 , pp. 172-180
    • Ballard, F.J.1
  • 24
    • 0024474441 scopus 로고
    • The effect of epidermal growth factor on membrane potential. Rapid hyperpolarization followed by persistent fluctuations
    • Pandiella A, Magni M, Lovisolo D, Meldolesi J. The effect of epidermal growth factor on membrane potential. Rapid hyperpolarization followed by persistent fluctuations. J Biol Chem 1989;264:12914-21.
    • (1989) J Biol Chem , vol.264 , pp. 12914-12921
    • Pandiella, A.1    Magni, M.2    Lovisolo, D.3    Meldolesi, J.4
  • 25
    • 0031959657 scopus 로고    scopus 로고
    • Genetic engineering of proteins with cell membrane permeability
    • Rojas M, Donahue JP, Tan Z, Lin YZ. Genetic engineering of proteins with cell membrane permeability. Nat Biotechnol 1998;16:370-5.
    • (1998) Nat Biotechnol , vol.16 , pp. 370-375
    • Rojas, M.1    Donahue, J.P.2    Tan, Z.3    Lin, Y.Z.4
  • 26
    • 0031984072 scopus 로고    scopus 로고
    • Trojan peptides: The penetration system for intracellular delivery
    • Derossi D, Chassaing G, Prochiantz A. Trojan peptides: The penetration system for intracellular delivery. Trends Cell Biol 1998;8:84-7.
    • (1998) Trends Cell Biol , vol.8 , pp. 84-87
    • Derossi, D.1    Chassaing, G.2    Prochiantz, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.