In vivo PDGF β receptor activation in the dorsocaudal brainstem of the rat prevents hypoxia-induced apoptosis via activation of Akt and BAD

Brain Research

Volumn 895, Issue 1-2, 2001, Pages 111-118

  Simakajornboon, Narong ^a   Szerlip, Nicholas J ^a   Gozal, Evelyne ^b   Anonetapipat, James W ^a   Gozal, David ^b  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b University of Louisville School of Medicine   (United States)

Author keywords

Apoptosis; Cell survival; Growth factor; Hypoxia; Phosphoinositol triphosphate

Indexed keywords

CASPASE 3; DRUG VEHICLE; IMATINIB; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN; PROTEIN BAD; PROTEIN KINASE B; PROTEIN TYROSINE KINASE INHIBITOR; SERINE; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; BRAIN PROTECTION; BRAIN STEM; CONTROLLED STUDY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; HYPOXIA; MALE; METABOLIC ACTIVATION; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; RAT; REACTION TIME; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BCL-ASSOCIATED DEATH PROTEIN; CARRIER PROTEINS; CASPASES; CELL SURVIVAL; DNA, SINGLE-STRANDED; ENZYME INHIBITORS; HYPOXIA, BRAIN; IMMUNOHISTOCHEMISTRY; MALE; NERVE DEGENERATION; NEURONS; NEUROPROTECTIVE AGENTS; PHOSPHORYLATION; PIPERAZINES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PYRIMIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RESPIRATORY PHYSIOLOGY; SIGNAL TRANSDUCTION; SOLITARY NUCLEUS;

EID: 0035937513     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)02054-6     Document Type: Article

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