Trimetazidine, administered at the onset of reperfusion, ameliorates myocardial dysfunction and injury by activation of p38 mitogen-activated protein kinase and akt signaling

Journal of Pharmacology and Experimental Therapeutics

Volumn 333, Issue 2, 2010, Pages 421-429

  Khan, Mahmood ^a   Meduru, Sarath ^a   Mostafa, Mahmoud ^a   Khan, Saniya ^a   Hideg, Kàlmàn ^b   Kuppusamy, Periannan ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF PÉCS   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CREATINE KINASE; FREE RADICAL; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; TRIMETAZIDINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION SIZE; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ELECTRON SPIN RESONANCE; ENZYME ACTIVATION; HEART EJECTION FRACTION; HEART FUNCTION; HEART MUSCLE INJURY; HEART PROTECTION; HYPEROXIA; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NONHUMAN; OXIMETRY; OXYGENATION; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION; TISSUE HOMOGENATE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CREATINE KINASE; ECHOCARDIOGRAPHY; ENZYME ACTIVATION; FREE RADICAL SCAVENGERS; MALE; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NITRIC OXIDE; OXIMETRY; OXYGEN; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SUPEROXIDES; TRIMETAZIDINE; VASODILATOR AGENTS;

EID: 77951080081     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.165175     Document Type: Article

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