Cardioprotection by sulfaphenazole, a cytochrome P450 inhibitor: Mitigation of ischemia-reperfusion injury by scavenging of reactive oxygen species

Journal of Pharmacology and Experimental Therapeutics

Volumn 323, Issue 3, 2007, Pages 813-821

  Khan, Mahmood ^a   Mohan, Iyyapu K ^a   Kutala, Vijay Kumar ^a   Kumbala, Damodar ^a   Kuppusamy, Periannan ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 2C9; CYTOCHROME P450 INHIBITOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; SULFAPHENAZOLE; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DRUG ACTIVITY; DRUG EFFECT; DRUG INHIBITION; HEART FUNCTION; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; ISOLATED HEART; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

ANIMALS; CREATINE KINASE; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INHIBITORS; FREE RADICAL SCAVENGERS; L-LACTATE DEHYDROGENASE; MALE; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NITRIC OXIDE; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SULFAPHENAZOLE;

EID: 36349025353     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.107.129486     Document Type: Article

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