Cytoprotective effect of sodium orthovanadate on ischemia/reperfusion- induced injury in the rat heart involves Akt activation and inhibition of fodrin breakdown and apoptosis

Journal of Pharmacology and Experimental Therapeutics

Volumn 311, Issue 3, 2004, Pages 1249-1255

  Takada, Yoko ^a   Hashimoto, Masami ^a   Kasahara, Jiro ^a   Aihara, Kazuyuki ^b   Fukunaga, Kohji ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b TOA EIYO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; DRUG VEHICLE; FODRIN; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAD; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; VANADATE SODIUM;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BLOOD PRESSURE; BLOTTING, WESTERN; CARRIER PROTEINS; CASPASE 3; CASPASES; MALE; MICROFILAMENT PROTEINS; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; MYOCYTES, CARDIAC; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; VANADATES; VENTRICULAR FUNCTION, LEFT;

EID: 10044279180     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.070839     Document Type: Article

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