Development of a proteolytically stable retro-inverso peptide inhibitor of β-amyloid oligomerization as a potential novel treatment for Alzheimers Disease

Biochemistry

Volumn 49, Issue 15, 2010, Pages 3261-3272

  Taylor, Mark ^a   Moore, Susan ^a   Mayes, Jennifer ^a   Parkin, Edward ^a   Beeg, Marten ^b   Canovi, Mara ^b   Gobbi, Marco ^b   Mann, David M A ^c   Allsop, David ^a  

^a LANCASTER UNIVERSITY   (United Kingdom)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMERS DISEASE; CELL TOXICITY; FURTHER DEVELOPMENT; HUMAN PLASMAS; NEUROBLASTOMA CELLS; PEPTIDE INHIBITORS; SDS-PAGE; THIOFLAVIN T; UNDERLYING CAUSE;

ATOMIC FORCE MICROSCOPY; GLYCOPROTEINS; OLIGOMERIZATION; PEPTIDES; SURFACE PLASMON RESONANCE; TOXICITY;

OLIGOMERS;

AMYLOID BETA PROTEIN; BRAIN EXTRACT; PEPTIDE DERIVATIVE; THIOFLAVINE;

ALZHEIMER DISEASE; ARTICLE; ATOMIC FORCE MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; IMMUNOASSAY; PLASMA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; SURFACE PLASMON RESONANCE;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; ANIMALS; CELL AGGREGATION; CELL LINE; CELL SURVIVAL; HUMANS; IMMUNOASSAY; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PEPTIDES; SURFACE PLASMON RESONANCE; THIAZOLES;

EID: 77950937554     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi100144m     Document Type: Article

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