CD40/CD40L interaction induces Aβ production and increases γ-secretase activity independently of tumor necrosis factor receptor associated factor (TRAF) signaling

Experimental Cell Research

Volumn 315, Issue 13, 2009, Pages 2265-2274

  Volmar, Claude Henry ^a,b,c   Ait Ghezala, Ghania ^a,b,c   Frieling, Jeremy ^a   Weeks, Ophelia I ^c   Mullan, Michael J ^a,b,c  

^a ROSKAMP INSTITUTE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c FLORIDA INTERNATIONAL UNIVERSITY   (United States)

Author keywords

Alzheimer's disease; Amyloid; CD40; TRAF; secretase

Indexed keywords

ALPHA SECRETASE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; BETA SECRETASE; CD40 ANTIGEN; CD40 LIGAND; GAMMA SECRETASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR;

ALZHEIMER DISEASE; ARTICLE; CELL MUTANT; CONTROLLED STUDY; DATA ANALYSIS; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NEUROBLASTOMA CELL; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; TUMOR CELL LINE;

EID: 67349240843     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2009.04.023     Document Type: Article

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