Opposite effects of simvastatin on the bactericidal and inflammatory response of macrophages to opsonized S. aureus

Journal of Leukocyte Biology

Volumn 87, Issue 3, 2010, Pages 433-442

  Benati, Daniela ^a   Ferro, Micol ^a   Savino, Maria Teresa ^a   Ulivieri, Cristina ^a   Schiavo, Ebe ^a   Nuccitelli, Annalisa ^b   Pasini, Franco Laghi ^a   Baldari, Cosima T ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b NOVARTIS VACCINES AND DIAGNOSTICS   (Italy)

Author keywords

Fc receptors; Oxidative burst; Phagocytosis; Protein prenylation; Ras superfamily GTpases; Statins

Indexed keywords

CYCLOOXYGENASE 2; FC RECEPTOR; IMMUNOGLOBULIN G; MEVINOLIN; RAS PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SIMVASTATIN; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; ACTIN; AUTACOID; OPSONIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; MACROPHAGE; MACROPHAGE FUNCTION; MOUSE; NONHUMAN; OPSONIZATION; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN PRENYLATION; PROTEIN TARGETING; RESPIRATORY BURST; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS; ANIMAL; CELL LINE; CELL MEMBRANE; CYTOLOGY; CYTOSKELETON; ENZYMOLOGY; IMMUNOLOGY; INFLAMMATION; METABOLISM; MICROBIAL VIABILITY; MICROBIOLOGY;

STAPHYLOCOCCUS AUREUS;

ACTINS; ANIMALS; CELL LINE; CYTOSKELETON; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; MACROPHAGES; MEMBRANE MICRODOMAINS; MICE; MICROBIAL VIABILITY; OPSONIN PROTEINS; PHAGOCYTOSIS; PROTEIN PRENYLATION; RAS PROTEINS; RECEPTORS, IGG; RESPIRATORY BURST; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; SIMVASTATIN; STAPHYLOCOCCUS AUREUS;

EID: 77950366186     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0409273     Document Type: Article

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