메뉴 건너뛰기




Volumn 19, Issue 4, 2010, Pages 1283-1294

Apolipoprotein e promoter polymorphisms and risk of Alzheimer's disease: Evidence from meta-analysis

Author keywords

219T G; 427T C; 491A T; Alzheimer's disease; APOE promoter; Meta analysis

Indexed keywords

APOLIPOPROTEIN E;

EID: 77950364668     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2010-1329     Document Type: Article
Times cited : (31)

References (68)
  • 4
    • 38349146483 scopus 로고    scopus 로고
    • Apolipoprotein e and Alzheimer's disease: Molecular mechanisms and therapeutic opportunities
    • Cedazo-Mínguez A (2007) Apolipoprotein E and Alzheimer's disease: molecular mechanisms and therapeutic opportunities. J Cell Mol Med 11, 1227-1238.
    • (2007) J Cell Mol Med , vol.11 , pp. 1227-1238
    • Cedazo-Mínguez, A.1
  • 9
    • 7744222619 scopus 로고    scopus 로고
    • Metaanalysis of genetic studies in ischemic stroke. Thirty-two genes involving approximately 18000 cases and 58000 controls
    • Casas JP, Hingorani AD, Bautista LE, Sharma P (2004) Metaanalysis of genetic studies in ischemic stroke. Thirty-two genes involving approximately 18000 cases and 58000 controls. Arch Neurol 61, 1652-1662.
    • (2004) Arch Neurol , vol.61 , pp. 1652-1662
    • Casas, J.P.1    Hingorani, A.D.2    Bautista, L.E.3    Sharma, P.4
  • 10
    • 1542357656 scopus 로고    scopus 로고
    • Meta-analysis of the association of cathepsin D Ala224Val gene polymorphism with the risk of Alzheimer's disease: A HuGE gene-disease association review
    • Ntais C, Polycarpou A, Ioannidis JP (2004) Meta-analysis of the association of cathepsin D Ala224Val gene polymorphism with the risk of Alzheimer's disease: a HuGE gene-disease association review. Am J Epidemiol 159, 527-536.
    • (2004) Am J Epidemiol , vol.159 , pp. 527-536
    • Ntais, C.1    Polycarpou, A.2    Ioannidis, J.P.3
  • 14
    • 0037442235 scopus 로고    scopus 로고
    • Genetic associations in large versus small studies: An empirical assessment
    • Ioannidis JP, Trikalinos TA, Ntzani EE, Contopoulos- IoannidisDG(2003) Genetic associations in large versus small studies: an empirical assessment. Lancet 361, 567-571.
    • (2003) Lancet , vol.361 , pp. 567-571
    • Ioannidis, J.P.1    Trikalinos, T.A.2    Ntzani, E.E.3    Ioannidisdg, C.4
  • 15
    • 60149084354 scopus 로고    scopus 로고
    • Variants of the arachidonate 5-lipoxygense- activating protein (ALOX5AP) gene and risk of stroke: A HuGE gene-disease association review and meta-analysis
    • Zintzaras E, Rodopoulou P, Sakellaridis N (2009) Variants of the arachidonate 5-lipoxygense- activating protein (ALOX5AP) gene and risk of stroke: a HuGE gene-disease association review and meta-analysis. Am J Epidemiol 169, 523-532.
    • (2009) Am J Epidemiol , vol.169 , pp. 523-532
    • Zintzaras, E.1    Rodopoulou, P.2    Sakellaridis, N.3
  • 16
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc B 57, 289-300.
    • (1995) J R Stat Soc B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 17
    • 0002294347 scopus 로고
    • A simple sequentially rejective bonferroni test procedure
    • Holm S (1979) A Simple Sequentially Rejective Bonferroni Test Procedure. Scand J Stat 6, 65-70.
    • (1979) Scand J Stat , vol.6 , pp. 65-70
    • Holm, S.1
  • 18
    • 0035459399 scopus 로고    scopus 로고
    • The power of statistical tests in meta-analysis
    • Hedges LV, Pigott TD (2001) The power of statistical tests in meta-analysis. Psychol Methods 6, 203-217.
    • (2001) Psychol Methods , vol.6 , pp. 203-217
    • Hedges, L.V.1    Pigott, T.D.2
  • 19
    • 0034663172 scopus 로고    scopus 로고
    • Apolipoprotein e gene promoter polymorphisms in Alzheimer's disease
    • Bullido MJ, Valdivieso F (2000) Apolipoprotein E gene promoter polymorphisms in Alzheimer's disease. Microsc Res Tech 50, 261-267.
    • (2000) Microsc Res Tech , vol.50 , pp. 261-267
    • Bullido, M.J.1    Valdivieso, F.2
  • 20
    • 0037345672 scopus 로고    scopus 로고
    • Expanding the association between the APOE gene and the risk of Alzheimer's disease: Possible roles for APOE promoter polymorphisms and alterations in APOE trascription
    • Laws SM, Hone E, Gandy S, Martins RN (2003) Expanding the association between the APOE gene and the risk of Alzheimer's disease: possible roles for APOE promoter polymorphisms and alterations in APOE trascription. J Neurochem 84, 1215-1236.
    • (2003) J Neurochem , vol.84 , pp. 1215-1236
    • Laws, S.M.1    Hone, E.2    Gandy, S.3    Martins, R.N.4
  • 23
    • 0037036908 scopus 로고    scopus 로고
    • Identification of a protective allele against Alzheimer disease in the APOE gene promoter
    • Beyer K, Lao JI, Ǵomez M, Riutort N, Latorre P, Mate JL, Ariza A (2002) Identification of a protective allele against Alzheimer disease in the APOE gene promoter. Neuroreport 13, 1403-1405.
    • (2002) Neuroreport , vol.13 , pp. 1403-1405
    • Beyer, K.1    Lao, J.I.2    Ǵomez, M.3    Riutort, N.4    Latorre, P.5    Mate, J.L.6    Ariza, A.7
  • 31
    • 0032563366 scopus 로고    scopus 로고
    • The -491A/T apolipoprotein e promoter polymorphism association with Alzheimer's disease: Independent risk and linkage disequilibrium with the known APOE polymorphism
    • Town T, Paris D, Fallin D, Duara R, Barker W, Gold M, Crawford F, Mullan M (1998) The -491A/T apolipoprotein E promoter polymorphism association with Alzheimer's disease: independent risk and linkage disequilibrium with the known APOE polymorphism. Neurosci Lett 252, 95-98.
    • (1998) Neurosci Lett , vol.252 , pp. 95-98
    • Town, T.1    Paris, D.2    Fallin, D.3    Duara, R.4    Barker, W.5    Gold, M.6    Crawford, F.7    Mullan, M.8
  • 33
    • 0033605707 scopus 로고    scopus 로고
    • The -491A/T polymorphism of the Apolipoprotein e gene is associated with the ApoEepsilon4 allele and Alzheimer's disease
    • Ahmed AR, MacGowan SH, Culpan D, Jones RW, Wilcock GK (1999) The -491A/T polymorphism of the Apolipoprotein E gene is associated with the ApoEepsilon4 allele and Alzheimer's disease. Neurosci Lett 263, 217-219.
    • (1999) Neurosci Lett , vol.263 , pp. 217-219
    • Ahmed, A.R.1    MacGowan, S.H.2    Culpan, D.3    Jones, R.W.4    Wilcock, G.K.5
  • 34
    • 0033521635 scopus 로고    scopus 로고
    • Apolipoprotein e promoter polymorphism and sporadic Alzheimer's disease in a Japanese population
    • Toji H, Maruyama H, Sasaki K, Nakamura S, Kawakami H (1999) Apolipoprotein E promoter polymorphism and sporadic Alzheimer's disease in a Japanese population. Neurosci Lett 259, 56-58.
    • (1999) Neurosci Lett , vol.259 , pp. 56-58
    • Toji, H.1    Maruyama, H.2    Sasaki, K.3    Nakamura, S.4    Kawakami, H.5
  • 41
    • 0034642230 scopus 로고    scopus 로고
    • Effect of APOE genotype and promoter polymorphism on risk of Alzheimer's disease
    • Wang JC, Kwon JM, Shah P, Morris JC, Goate A (2000) Effect of APOE genotype and promoter polymorphism on risk of Alzheimer's disease. Neurology 55, 1644-1649.
    • (2000) Neurology , vol.55 , pp. 1644-1649
    • Wang, J.C.1    Kwon, J.M.2    Shah, P.3    Morris, J.C.4    Goate, A.5
  • 44
    • 17144469201 scopus 로고    scopus 로고
    • Alzheimer's risk associated with human apolipoprotein E, alpha-2 macroglobulin and lipoprotein receptor related protein polymorphisms: Absence of genetic interactions, and modulation by gender
    • Bullido MJ, Guallar-Castilĺon P, Artiga MJ, Ramos MC, Sastre I, Aldudo J, Frank A, Coria F, Rodríguez-Artalejo F,Valdivieso F (2000) Alzheimer's risk associated with human apolipoprotein E, alpha-2 macroglobulin and lipoprotein receptor related protein polymorphisms: absence of genetic interactions, and modulation by gender. Neurosci Lett 289, 213-216.
    • (2000) Neurosci Lett , vol.289 , pp. 213-216
    • Bullido, M.J.1    Guallar-Castilĺon, P.2    Artiga, M.J.3    Ramos, M.C.4    Sastre, I.5    Aldudo, J.6    Frank, A.7    Coria, F.8    Rodríguez-Artalejo, F.9    Valdivieso, F.10
  • 45
    • 0035124734 scopus 로고    scopus 로고
    • Polymorphisms of the apolipoprotein e gene regulatory region and of the LDL receptor gene in late-onset Alzheimer's disease in relation to the plasma lipidic pattern
    • Scacchi R, Gambina G, Martini MC, Ruggeri M, Ferrari G, Silvestri M, Schiavon R, Corbo RM (2001) Polymorphisms of the apolipoprotein E gene regulatory region and of the LDL receptor gene in late-onset Alzheimer's disease in relation to the plasma lipidic pattern. Dement Geriatr Cogn Disord 12, 63-68.
    • (2001) Dement Geriatr Cogn Disord , vol.12 , pp. 63-68
    • Scacchi, R.1    Gambina, G.2    Martini, M.C.3    Ruggeri, M.4    Ferrari, G.5    Silvestri, M.6    Schiavon, R.7    Corbo, R.M.8
  • 47
    • 0035826546 scopus 로고    scopus 로고
    • Investigation of association of 13 polymorphisms in eight genes in southeastern African American Alzheimer disease patients as compared to age-matched controls
    • Perry RT, Collins JS, Harrell LE, Acton RT, Go RC (2001) Investigation of association of 13 polymorphisms in eight genes in southeastern African American Alzheimer disease patients as compared to age-matched controls. Am J Med Genet 105, 332-342.
    • (2001) Am J Med Genet , vol.105 , pp. 332-342
    • Perry, R.T.1    Collins, J.S.2    Harrell, L.E.3    Acton, R.T.4    Go, R.C.5
  • 49
    • 0037025116 scopus 로고    scopus 로고
    • The Th1/E47cs-G apolipo- protein e (APOE) promoter allele is a risk factor for Alzheimer disease of very later onset
    • Beyer K, Lao JI, Ǵomez M, Riutort N, Latorre P, Mate JL, Ariza A (2002) The Th1/E47cs-G apolipo- protein E (APOE) promoter allele is a risk factor for Alzheimer disease of very later onset. Neurosci Lett 326, 187-190.
    • (2002) Neurosci Lett , vol.326 , pp. 187-190
    • Beyer, K.1    Lao, J.I.2    Ǵomez, M.3    Riutort, N.4    Latorre, P.5    Mate, J.L.6    Ariza, A.7
  • 53
    • 0037497125 scopus 로고    scopus 로고
    • A study on the relation between the apolipoprotein e promoter -427C/T polymorphism and Alzheimer's disease
    • Tang GM, Zhang MY, Jiang SD, Qian YP,Wang DX (2003) A study on the relation between the apolipoprotein E promoter -427C/T polymorphism and Alzheimer's disease. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 20, 244-246.
    • (2003) Zhonghua Yi Xue Yi Chuan Xue Za Zhi , vol.20 , pp. 244-246
    • Tang, G.M.1    Zhang, M.Y.2    Jiang, S.D.3    Qian Ypwang, D.X.4
  • 54
    • 0142075287 scopus 로고    scopus 로고
    • Apolipoprotein e -491 promoter polymorphism is an independent risk factor for Alzheimer's disease in the Chinese population
    • Yang JD, Feng GY, Zhang J, Cheung J, St Clair D, He L, Ichimura K (2003) Apolipoprotein E -491 promoter polymorphism is an independent risk factor for Alzheimer's disease in the Chinese population. Neurosci Lett 350, 25-28.
    • (2003) Neurosci Lett , vol.350 , pp. 25-28
    • Yang, J.D.1    Feng, G.Y.2    Zhang, J.3    Cheung, J.4    St Clair, D.5    He, L.6    Ichimura, K.7
  • 55
    • 0142091468 scopus 로고    scopus 로고
    • Haplogroup analysis of the risk associated with APOE promoter polymorphisms (-219T/G, -491A/T and -427T/C) in Colombian Alzheimer's disease patients
    • Parra-Bonilla G, Arboleda G, Yunis J, Solano E, Pardo R, Arango G, Hedmont D, Arboleda H (2003) Haplogroup analysis of the risk associated with APOE promoter polymorphisms (-219T/G, -491A/T and -427T/C) in Colombian Alzheimer's disease patients. Neurosci Lett 349, 159-162.
    • (2003) Neurosci Lett , vol.349 , pp. 159-162
    • Parra-Bonilla, G.1    Arboleda, G.2    Yunis, J.3    Solano, E.4    Pardo, R.5    Arango, G.6    Hedmont, D.7    Arboleda, H.8
  • 56
    • 3042701772 scopus 로고    scopus 로고
    • APOE promoter, ACEI and CYP46 polymorphisms and ?-amyloid in Alzheimer's disease
    • Chalmers KA, Culpan D, Kehoe PG,Wilcock GK, Hughes A, Love S (2004) APOE promoter, ACEI and CYP46 polymorphisms and ?-amyloid in Alzheimer's disease. Neuroreport 15, 95-98.
    • (2004) Neuroreport , vol.15 , pp. 95-98
    • Chalmers, K.A.1    Culpan, D.2    Kehoe Pgwilcock, G.K.3    Hughes, A.4    Love, S.5
  • 58
    • 23944523570 scopus 로고    scopus 로고
    • ApoE - 491A/T promoter polymorphism is not an independent risk factor, but associated with the epsilon4 allele in Hungarian Alzheimer's dementia population
    • Juh́asz A, Palot́as A, Janka Z, Rimańoczy A, Palot́as M, B́odi N, Boda K, Zana M, Vincze G, Ḱalḿan J (2005) ApoE - 491A/T promoter polymorphism is not an independent risk factor, but associated with the epsilon4 allele in Hungarian Alzheimer's dementia population. Neurochem Res 30, 591-596.
    • (2005) Neurochem Res , vol.30 , pp. 591-596
    • Juh́asz, A.1    Palot́as, A.2    Janka, Z.3    Rimańoczy, A.4    Palot́as, M.5    B́odi, N.6    Boda, K.7    Zana, M.8    Vincze, G.9    Ḱalḿan, J.10
  • 61
    • 50349083512 scopus 로고    scopus 로고
    • Apolipoprotein e promoter polymorphisms (- 491A/T and -427T/C) and Alzheimer's disease: No evidence of association in the Irish population
    • Lynch CA, Brazil J, Cullen B, Coakley D, Gill M, Lawlor BA, Hawi Z (2008) Apolipoprotein E promoter polymorphisms (- 491A/T and -427T/C) and Alzheimer's disease: no evidence of association in the Irish population. Ir J Med Sci 177, 29-33.
    • (2008) Ir J Med Sci , vol.177 , pp. 29-33
    • Lynch, C.A.1    Brazil, J.2    Cullen, B.3    Coakley, D.4    Gill, M.5    Lawlor, B.A.6    Hawi, Z.7
  • 63
    • 61849090884 scopus 로고    scopus 로고
    • The role of the -427T/C apolipoprotein e promoter polymorphism in the pathogenesis of Alzheimer's disease, vascular dementia and mixed dementia
    • Trebunov́a M, Slab́a E, Habalov́a V, Gdovinov́a Z (2009) The role of the -427T/C apolipoprotein E promoter polymorphism in the pathogenesis of Alzheimer's disease, vascular dementia and mixed dementia. Neural Transm 116, 339-344.
    • (2009) Neural Transm , vol.116 , pp. 339-344
    • Trebunov́a, M.1    Slab́a, E.2    Habalov́a, V.3    Gdovinov́a, Z.4
  • 66
  • 68
    • 33845892752 scopus 로고    scopus 로고
    • Systematic meta-analyses of Alzheimer disease genetic association studies: The AlzGene database
    • Bertram L, McQueen MB, Mullin K, Blacker D, Tanzi RE (2007) Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. Nat Genet 39, 17-23.
    • (2007) Nat Genet , vol.39 , pp. 17-23
    • Bertram, L.1    McQueen, M.B.2    Mullin, K.3    Blacker, D.4    Tanzi, R.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.