-
1
-
-
18244428862
-
Incidence of dementia and major subtypes in Europe: A collaborative study of population-based cohorts
-
Neurologic Diseases in the Elderly Research Group
-
Fratiglioni L, Launer LJ, Andersen K, Breteler MM, Copeland JR, Dartigues JF, Lobo A, Martinez-Lage J, Soininen H, Hofman A (2000) Incidence of dementia and major subtypes in Europe: A collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology 54, S10-15.
-
(2000)
Neurology
, vol.54
-
-
Fratiglioni, L.1
Launer, L.J.2
Andersen, K.3
Breteler, M.M.4
Copeland, J.R.5
Dartigues, J.F.6
Lobo, A.7
Martinez-Lage, J.8
Soininen, H.9
Hofman, A.10
-
2
-
-
67549147148
-
Effect of APOE genotype on amyloid plaque load and gray matter volume in Alzheimer disease
-
Drzezga A, Grimmer T, Henriksen G, Mühlau M, Perneczky R, Miederer I, Praus C, Sorg C, Wohlschläger A, Riemenschneider M, Wester HJ, Foerstl H, Schwaiger M, Kurz A (2009) Effect of APOE genotype on amyloid plaque load and gray matter volume in Alzheimer disease. Neurology 72, 1487-1494.
-
(2009)
Neurology
, vol.72
, pp. 1487-1494
-
-
Drzezga, A.1
Grimmer, T.2
Henriksen, G.3
Mühlau, M.4
Perneczky, R.5
Miederer, I.6
Praus, C.7
Sorg, C.8
Wohlschläger, A.9
Riemenschneider, M.10
Wester, H.J.11
Foerstl, H.12
Schwaiger, M.13
Kurz, A.14
-
3
-
-
50349083801
-
Ceramide is responsible for the failure of compensatory nerve sprouting in apolipoprotein e knock-out mice
-
Maysinger D, Holmes M, Han X, Epand RM, Pertens E, Foerster A, Barlas C, Holtzman DM, Diamond J (2008) Ceramide is responsible for the failure of compensatory nerve sprouting in apolipoprotein E knock-out mice. J Neurosci 28, 7891-7899.
-
(2008)
J Neurosci
, vol.28
, pp. 7891-7899
-
-
Maysinger, D.1
Holmes, M.2
Han, X.3
Epand, R.M.4
Pertens, E.5
Foerster, A.6
Barlas, C.7
Holtzman, D.M.8
Diamond, J.9
-
4
-
-
38349146483
-
Apolipoprotein e and Alzheimer's disease: Molecular mechanisms and therapeutic opportunities
-
Cedazo-Mínguez A (2007) Apolipoprotein E and Alzheimer's disease: molecular mechanisms and therapeutic opportunities. J Cell Mol Med 11, 1227-1238.
-
(2007)
J Cell Mol Med
, vol.11
, pp. 1227-1238
-
-
Cedazo-Mínguez, A.1
-
5
-
-
0027337858
-
Apolipoprotein e epsilon 4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases
-
Saunders AM, Schmader K, Breitner JC, Benson MD, Brown WT, Goldfarb L, Goldgaber D, Manwaring MG, Szymanski MH, McCown N (1993) Apolipoprotein E epsilon 4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases. Lancet 342, 710-711.
-
(1993)
Lancet
, vol.342
, pp. 710-711
-
-
Saunders, A.M.1
Schmader, K.2
Breitner, J.C.3
Benson, M.D.4
Brown, W.T.5
Goldfarb, L.6
Goldgaber, D.7
Manwaring, M.G.8
Szymanski, M.H.9
McCown, N.10
-
6
-
-
0028178047
-
Apolipoprotein E, epsilon 4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: Analysis of the 19q13.2 chromosomal region
-
Chartier-Harlin MC, Parfitt M, Legrain S, Ṕerez-Tur J, Brousseau T, Evans A, Berr C, Vidal O, Roques P, Gourlet V, Fruchart JC, Delacourte A, Rossor M, Amouye P (1994) Apolipoprotein E, epsilon 4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region. Hum Mol Genet 3, 569-574.
-
(1994)
Hum Mol Genet
, vol.3
, pp. 569-574
-
-
Chartier-Harlin, M.C.1
Parfitt, M.2
Legrain, S.3
Ṕerez-Tur, J.4
Brousseau, T.5
Evans, A.6
Berr, C.7
Vidal, O.8
Roques, P.9
Gourlet, V.10
Fruchart, J.C.11
Delacourte, A.12
Rossor, M.13
Amouye, P.14
-
7
-
-
0030723043
-
Distortion of allelic expression of apolipoprotein e in Alzheimer's disease
-
Lambert JC, Ṕerez-Tur J, Dupire MJ, Galasko D, Mann D, Amouyel P, Hardy J, Delacourte A, Chartier-Harlin MC (1997) Distortion of allelic expression of apolipoprotein E in Alzheimer's disease. Hum Mol Genet 6, 2151-2154.
-
(1997)
Hum Mol Genet
, vol.6
, pp. 2151-2154
-
-
Lambert, J.C.1
Ṕerez-Tur, J.2
Dupire, M.J.3
Galasko, D.4
Mann, D.5
Amouyel, P.6
Hardy, J.7
Delacourte, A.8
Chartier-Harlin, M.C.9
-
8
-
-
0032498118
-
Allelic polymorphism in the trascriptional region of apolipoprotein e gene
-
Artiga MJ, Bullido MJ, Sastre I, Recuero M, García MA, Aldudo J, V́azquez J, Valdivieso F (1998). Allelic polymorphism in the trascriptional region of apolipoprotein E gene. FEBS Lett 421, 105-108.
-
(1998)
FEBS Lett
, vol.421
, pp. 105-108
-
-
Artiga, M.J.1
Bullido, M.J.2
Sastre, I.3
Recuero, M.4
García, M.A.5
Aldudo, J.6
V́azquez, J.7
Valdivieso, F.8
-
9
-
-
7744222619
-
Metaanalysis of genetic studies in ischemic stroke. Thirty-two genes involving approximately 18000 cases and 58000 controls
-
Casas JP, Hingorani AD, Bautista LE, Sharma P (2004) Metaanalysis of genetic studies in ischemic stroke. Thirty-two genes involving approximately 18000 cases and 58000 controls. Arch Neurol 61, 1652-1662.
-
(2004)
Arch Neurol
, vol.61
, pp. 1652-1662
-
-
Casas, J.P.1
Hingorani, A.D.2
Bautista, L.E.3
Sharma, P.4
-
10
-
-
1542357656
-
Meta-analysis of the association of cathepsin D Ala224Val gene polymorphism with the risk of Alzheimer's disease: A HuGE gene-disease association review
-
Ntais C, Polycarpou A, Ioannidis JP (2004) Meta-analysis of the association of cathepsin D Ala224Val gene polymorphism with the risk of Alzheimer's disease: a HuGE gene-disease association review. Am J Epidemiol 159, 527-536.
-
(2004)
Am J Epidemiol
, vol.159
, pp. 527-536
-
-
Ntais, C.1
Polycarpou, A.2
Ioannidis, J.P.3
-
11
-
-
23944438473
-
Large meta-analysis establishes theACEinsertion-deletion polymorphism as a marker of Alzheimer's disease
-
Lehmann DJ, Cortina-Borja M, Warden DR, Smith AD, Sleegers K, Prince JA, van Duijn CM, Kehoe PG (2005) Large meta-analysis establishes theACEinsertion-deletion polymorphism as a marker of Alzheimer's disease. Am J Epidemiol 162, 305-317.
-
(2005)
Am J Epidemiol
, vol.162
, pp. 305-317
-
-
Lehmann, D.J.1
Cortina-Borja, M.2
Warden, D.R.3
Smith, A.D.4
Sleegers, K.5
Prince, J.A.6
Van Duijn, C.M.7
Kehoe, P.G.8
-
12
-
-
33747421698
-
Association between phosphodiesterase 4D gene and ischaemic stroke
-
Staton JM, Sayer MS, Hankey GJ, Attia J, Thakkinstian A, Yi Q, Cole VJ, Baker R, Eikelboom JW (2006) Association between phosphodiesterase 4D gene and ischaemic stroke. J Neurol Neurosurg Psychiatry 77, 1067-1069.
-
(2006)
J Neurol Neurosurg Psychiatry
, vol.77
, pp. 1067-1069
-
-
Staton, J.M.1
Sayer, M.S.2
Hankey, G.J.3
Attia, J.4
Thakkinstian, A.5
Yi, Q.6
Cole, V.J.7
Baker, R.8
Eikelboom, J.W.9
-
14
-
-
0037442235
-
Genetic associations in large versus small studies: An empirical assessment
-
Ioannidis JP, Trikalinos TA, Ntzani EE, Contopoulos- IoannidisDG(2003) Genetic associations in large versus small studies: an empirical assessment. Lancet 361, 567-571.
-
(2003)
Lancet
, vol.361
, pp. 567-571
-
-
Ioannidis, J.P.1
Trikalinos, T.A.2
Ntzani, E.E.3
Ioannidisdg, C.4
-
15
-
-
60149084354
-
Variants of the arachidonate 5-lipoxygense- activating protein (ALOX5AP) gene and risk of stroke: A HuGE gene-disease association review and meta-analysis
-
Zintzaras E, Rodopoulou P, Sakellaridis N (2009) Variants of the arachidonate 5-lipoxygense- activating protein (ALOX5AP) gene and risk of stroke: a HuGE gene-disease association review and meta-analysis. Am J Epidemiol 169, 523-532.
-
(2009)
Am J Epidemiol
, vol.169
, pp. 523-532
-
-
Zintzaras, E.1
Rodopoulou, P.2
Sakellaridis, N.3
-
16
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc B 57, 289-300.
-
(1995)
J R Stat Soc B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
17
-
-
0002294347
-
A simple sequentially rejective bonferroni test procedure
-
Holm S (1979) A Simple Sequentially Rejective Bonferroni Test Procedure. Scand J Stat 6, 65-70.
-
(1979)
Scand J Stat
, vol.6
, pp. 65-70
-
-
Holm, S.1
-
18
-
-
0035459399
-
The power of statistical tests in meta-analysis
-
Hedges LV, Pigott TD (2001) The power of statistical tests in meta-analysis. Psychol Methods 6, 203-217.
-
(2001)
Psychol Methods
, vol.6
, pp. 203-217
-
-
Hedges, L.V.1
Pigott, T.D.2
-
19
-
-
0034663172
-
Apolipoprotein e gene promoter polymorphisms in Alzheimer's disease
-
Bullido MJ, Valdivieso F (2000) Apolipoprotein E gene promoter polymorphisms in Alzheimer's disease. Microsc Res Tech 50, 261-267.
-
(2000)
Microsc Res Tech
, vol.50
, pp. 261-267
-
-
Bullido, M.J.1
Valdivieso, F.2
-
20
-
-
0037345672
-
Expanding the association between the APOE gene and the risk of Alzheimer's disease: Possible roles for APOE promoter polymorphisms and alterations in APOE trascription
-
Laws SM, Hone E, Gandy S, Martins RN (2003) Expanding the association between the APOE gene and the risk of Alzheimer's disease: possible roles for APOE promoter polymorphisms and alterations in APOE trascription. J Neurochem 84, 1215-1236.
-
(2003)
J Neurochem
, vol.84
, pp. 1215-1236
-
-
Laws, S.M.1
Hone, E.2
Gandy, S.3
Martins, R.N.4
-
21
-
-
0031911596
-
Anew polymorphism in the APOE promoter associated with risk of developing Alzheimer's disease
-
Lambert JC, Pasquier F, Cottel D, Frigard B, Amouyel P, Chartier-Harlin MC(1998) Anew polymorphism in the APOE promoter associated with risk of developing Alzheimer's disease. Hum Mol Genet 7, 533-540.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 533-540
-
-
Lambert, J.C.1
Pasquier, F.2
Cottel, D.3
Frigard, B.4
Amouyel, P.5
Chartier-Harlin, M.C.6
-
22
-
-
0037047008
-
Contribution of APOE promoter polymorphisms to Alzheimer's disease risk
-
Lambert JC, Araria-Goumidi L, Myllykangas L, Ellis C,Wang JC, Bullido MJ, Harris JM, Artiga MJ, Hernandez D, Kwon JM, Frigard B, Petersen RC, Cumming AM, Pasquier F, Sastre I, Tienari PJ, Frank A, Sulkava R, Morris JC, St Clair D, Mann DM, Wavrant-DeVrìeze F, Ezquerra-Trabalon M, Amouyel P, Hardy J, Haltia M, Valdivieso F, Goate AM, Ṕerez-Tur J, Lendon CL, Chartier-Harlin MC (2002) Contribution of APOE promoter polymorphisms to Alzheimer's disease risk. Neurology 59, 59-66.
-
(2002)
Neurology
, vol.59
, pp. 59-66
-
-
Lambert, J.C.1
Araria-Goumidi, L.2
Myllykangas, L.3
Ellis Cwang, J.C.4
Bullido, M.J.5
Harris, J.M.6
Artiga, M.J.7
Hernandez, D.8
Kwon, J.M.9
Frigard, B.10
Petersen, R.C.11
Cumming, A.M.12
Pasquier, F.13
Sastre, I.14
Tienari, P.J.15
Frank, A.16
Sulkava, R.17
Morris, J.C.18
St Clair, D.19
Mann, D.M.20
Wavrant-DeVrìeze, F.21
Ezquerra-Trabalon, M.22
Amouyel, P.23
Hardy, J.24
Haltia, M.25
Valdivieso, F.26
Goate, A.M.27
Ṕerez-Tur, J.28
Lendon, C.L.29
Chartier-Harlin, M.C.30
more..
-
23
-
-
0037036908
-
Identification of a protective allele against Alzheimer disease in the APOE gene promoter
-
Beyer K, Lao JI, Ǵomez M, Riutort N, Latorre P, Mate JL, Ariza A (2002) Identification of a protective allele against Alzheimer disease in the APOE gene promoter. Neuroreport 13, 1403-1405.
-
(2002)
Neuroreport
, vol.13
, pp. 1403-1405
-
-
Beyer, K.1
Lao, J.I.2
Ǵomez, M.3
Riutort, N.4
Latorre, P.5
Mate, J.L.6
Ariza, A.7
-
24
-
-
3042730989
-
APOE promoter polymorphisms and dementia in the elderly
-
Lambert JC, Berr C, Cottel D, Amouyel P, Helbecque N(2004) APOE promoter polymorphisms and dementia in the elderly. Neurosci Lett 365, 116-119.
-
(2004)
Neurosci Lett
, vol.365
, pp. 116-119
-
-
Lambert, J.C.1
Berr, C.2
Cottel, D.3
Amouyel, P.4
Helbecque, N.5
-
25
-
-
17344374322
-
A polymorphism in the regulatory region of APOE associated with risk of Alzheimer's dementia
-
Bullido MJ, Artiga MJ, Recuero M, Sastre I, García MA, Aldudo J, Lendon C, Han SW, Morris JC, Frank A, V́azquez J, Goate A, Valdivieso F (1998) A polymorphism in the regulatory region of APOE associated with risk of Alzheimer's dementia. Nat Genet 18, 69-71.
-
(1998)
Nat Genet
, vol.18
, pp. 69-71
-
-
Bullido, M.J.1
Artiga, M.J.2
Recuero, M.3
Sastre, I.4
García, M.A.5
Aldudo, J.6
Lendon, C.7
Han, S.W.8
Morris, J.C.9
Frank, A.10
V́azquez, J.11
Goate, A.12
Valdivieso, F.13
-
26
-
-
0032503943
-
Absence of association between Alzheimer disease and the -491 regulatory region polymorphism of APOE
-
Song YQ, Rogaeva E, Premkumar S, Brindle N, Kawarai T, Orlacchio A, Yu G, Levesque G, Nishimura M, Ikeda M, Pei Y, O'Toole C, Duara R, Barker W, Sorbi S, Freedman M, Farrer L, St George-Hyslop P (1998) Absence of association between Alzheimer disease and the -491 regulatory region polymorphism of APOE. Neurosci Lett 250, 189-192.
-
(1998)
Neurosci Lett
, vol.250
, pp. 189-192
-
-
Song, Y.Q.1
Rogaeva, E.2
Premkumar, S.3
Brindle, N.4
Kawarai, T.5
Orlacchio, A.6
Yu, G.7
Levesque, G.8
Nishimura, M.9
Ikeda, M.10
Pei, Y.11
O'Toole, C.12
Duara, R.13
Barker, W.14
Sorbi, S.15
Freedman, M.16
Farrer, L.17
St George-Hyslop, P.18
-
27
-
-
0032855024
-
Lack of independent associations of apolipoprotein e promoter and intron 1 polymorphisms with Alzheimer's disease
-
Rebeck GW, Cheung BS, Growdon WB, Deng A, Akuthota P, Locascio J, Greenberg SM, Hyman BT (1999) Lack of independent associations of apolipoprotein E promoter and intron 1 polymorphisms with Alzheimer's disease. Neurosci Lett 272, 155-158.
-
(1999)
Neurosci Lett
, vol.272
, pp. 155-158
-
-
Rebeck, G.W.1
Cheung, B.S.2
Growdon, W.B.3
Deng, A.4
Akuthota, P.5
Locascio, J.6
Greenberg, S.M.7
Hyman, B.T.8
-
28
-
-
0032545164
-
The -491A/T polymorphism in the regulatory region of the apolipoproteinEgene and early-onsetAlzheimer's disease
-
Roks G, Cruts M, Bullido MJ, Backhovens H, Artiga MJ, Hofman A, Valdivieso F, Van Broeckhoven C, Van Duijn CM (1998) The -491A/T polymorphism in the regulatory region of the apolipoproteinEgene and early-onsetAlzheimer's disease. Neurosci Lett 258, 65-68.
-
(1998)
Neurosci Lett
, vol.258
, pp. 65-68
-
-
Roks, G.1
Cruts, M.2
Bullido, M.J.3
Backhovens, H.4
Artiga, M.J.5
Hofman, A.6
Valdivieso, F.7
Van Broeckhoven, C.8
Van Duijn, C.M.9
-
29
-
-
4444229063
-
APOE and APOC1 promoter polymorphisms and the risk of Alzheimer disease in African and Caribbean Hispanic individuals
-
Tycko B, Lee JH, Ciappa A, Saxena A, Li CM, Feng L, Arriaga A, Stern Y, Lantigua R, Shachter N, Mayeux R (2004) APOE and APOC1 promoter polymorphisms and the risk of Alzheimer disease in African and Caribbean Hispanic individuals. Arch Neurol 61, 1434-1439.
-
(2004)
Arch Neurol
, vol.61
, pp. 1434-1439
-
-
Tycko, B.1
Lee, J.H.2
Ciappa, A.3
Saxena, A.4
Li, C.M.5
Feng, L.6
Arriaga, A.7
Stern, Y.8
Lantigua, R.9
Shachter, N.10
Mayeux, R.11
-
30
-
-
7844229878
-
Risk for Alzheimer's disease correlates with transcriptional activity of the APOE gene
-
Artiga MJ, Bullido MJ, Frank A, Sastre I, Recuero M, García MA, Lendon CL, Han SW, Morris JC, V́azquez J, Goate A, Valdivieso F (1998) Risk for Alzheimer's disease correlates with transcriptional activity of the APOE gene. Hum Mol Genet 7, 1887-1892.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 1887-1892
-
-
Artiga, M.J.1
Bullido, M.J.2
Frank, A.3
Sastre, I.4
Recuero, M.5
García, M.A.6
Lendon, C.L.7
Han, S.W.8
Morris, J.C.9
V́azquez, J.10
Goate, A.11
Valdivieso, F.12
-
31
-
-
0032563366
-
The -491A/T apolipoprotein e promoter polymorphism association with Alzheimer's disease: Independent risk and linkage disequilibrium with the known APOE polymorphism
-
Town T, Paris D, Fallin D, Duara R, Barker W, Gold M, Crawford F, Mullan M (1998) The -491A/T apolipoprotein E promoter polymorphism association with Alzheimer's disease: independent risk and linkage disequilibrium with the known APOE polymorphism. Neurosci Lett 252, 95-98.
-
(1998)
Neurosci Lett
, vol.252
, pp. 95-98
-
-
Town, T.1
Paris, D.2
Fallin, D.3
Duara, R.4
Barker, W.5
Gold, M.6
Crawford, F.7
Mullan, M.8
-
32
-
-
7344221464
-
Pronounced impact of Th1/E47cs mutation compared with -491 at mutation on neural APOE gene expression and risk of developing Alzheimer's disease
-
Lambert JC, Berr C, Pasquier F, Delacourte A, Frigard B, Cottel D, Ṕerez-Tur J, Mouroux V, Mohr M, Ćecyre D, Galasko D, Lendon C, Poirier J, Hardy J, Mann D, Amouyel P, Chartier-Harlin MC (1998) Pronounced impact of Th1/E47cs mutation compared with -491 AT mutation on neural APOE gene expression and risk of developing Alzheimer's disease. Hum Mol Genet 7, 1511-1516.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 1511-1516
-
-
Lambert, J.C.1
Berr, C.2
Pasquier, F.3
Delacourte, A.4
Frigard, B.5
Cottel, D.6
Ṕerez-Tur, J.7
Mouroux, V.8
Mohr, M.9
Ćecyre, D.10
Galasko, D.11
Lendon, C.12
Poirier, J.13
Hardy, J.14
Mann, D.15
Amouyel, P.16
Chartier-Harlin, M.C.17
-
33
-
-
0033605707
-
The -491A/T polymorphism of the Apolipoprotein e gene is associated with the ApoEepsilon4 allele and Alzheimer's disease
-
Ahmed AR, MacGowan SH, Culpan D, Jones RW, Wilcock GK (1999) The -491A/T polymorphism of the Apolipoprotein E gene is associated with the ApoEepsilon4 allele and Alzheimer's disease. Neurosci Lett 263, 217-219.
-
(1999)
Neurosci Lett
, vol.263
, pp. 217-219
-
-
Ahmed, A.R.1
MacGowan, S.H.2
Culpan, D.3
Jones, R.W.4
Wilcock, G.K.5
-
34
-
-
0033521635
-
Apolipoprotein e promoter polymorphism and sporadic Alzheimer's disease in a Japanese population
-
Toji H, Maruyama H, Sasaki K, Nakamura S, Kawakami H (1999) Apolipoprotein E promoter polymorphism and sporadic Alzheimer's disease in a Japanese population. Neurosci Lett 259, 56-58.
-
(1999)
Neurosci Lett
, vol.259
, pp. 56-58
-
-
Toji, H.1
Maruyama, H.2
Sasaki, K.3
Nakamura, S.4
Kawakami, H.5
-
35
-
-
0032878674
-
Promoter polymorphism (-491A/T) in the APOE gene of Finnish Alzheimer's disease patients and control individuals
-
Helisalmi S, Hiltunen M, Valonen P, Mannermaa A, Koivisto AM, Lehtovirta M, Ryynänen M, Soininen H (1999) Promoter polymorphism (-491A/T) in the APOE gene of Finnish Alzheimer's disease patients and control individuals. J Neurol 246, 821-824.
-
(1999)
J Neurol
, vol.246
, pp. 821-824
-
-
Helisalmi, S.1
Hiltunen, M.2
Valonen, P.3
Mannermaa, A.4
Koivisto, A.M.5
Lehtovirta, M.6
Ryynänen, M.7
Soininen, H.8
-
36
-
-
0033544307
-
APOE-491 promoter polymorphism is a risk factor for late-onset Alzheimer's disease
-
Casadei VM, Ferri C, Veglia F, Gavazzi A, Salani G, Cattaneo M, Sorbi S, Annoni G, Licastro F, Mariani C, Franceschi M, Grimaldi LM (1999) APOE-491 promoter polymorphism is a risk factor for late-onset Alzheimer's disease. Neurology 53, 1888-1889.
-
(1999)
Neurology
, vol.53
, pp. 1888-1889
-
-
Casadei, V.M.1
Ferri, C.2
Veglia, F.3
Gavazzi, A.4
Salani, G.5
Cattaneo, M.6
Sorbi, S.7
Annoni, G.8
Licastro, F.9
Mariani, C.10
Franceschi, M.11
Grimaldi, L.M.12
-
37
-
-
0032885851
-
Polymorphisms of the human apolipoprotein e promoter and bleomycin hydrolase gene: Risk factors for Alzheimer's dementia?
-
Thome J, Gewirtz JC, Sakai N, Zachariou V, Retz-Junginger P, RetzW, Duman RS, RöslerM(1999) Polymorphisms of the human apolipoprotein E promoter and bleomycin hydrolase gene: risk factors for Alzheimer's dementia? Neurosci Lett 274, 37-40.
-
(1999)
Neurosci Lett
, vol.274
, pp. 37-40
-
-
Thome, J.1
Gewirtz, J.C.2
Sakai, N.3
Zachariou, V.4
Retz-Junginger, P.5
Retz, W.6
Duman, R.S.7
Rösler, M.8
-
38
-
-
0033575492
-
Apolipoprotein e promoter and alpha2-macroglobulin polymorphisms are not genetically associated with Chinese late onset Alzheimer's disease
-
Chen L, Baum L, Ng HK, Chan LY, Sastre I, Artíga MJ, Valdivieso F, Bullido MJ, Chiu HF, Pang CP (1999) Apolipoprotein E promoter and alpha2-macroglobulin polymorphisms are not genetically associated with Chinese late onset Alzheimer's disease. Neurosci Lett 269, 173-177.
-
(1999)
Neurosci Lett
, vol.269
, pp. 173-177
-
-
Chen, L.1
Baum, L.2
Ng, H.K.3
Chan, L.Y.4
Sastre, I.5
Artíga, M.J.6
Valdivieso, F.7
Bullido, M.J.8
Chiu, H.F.9
Pang, C.P.10
-
39
-
-
0033577180
-
The -491AA polymorphism in the APOE gene is associated with increased plasma apoE levels in Alzheimer's disease
-
Laws SM, Taddei K, Martins G, Paton A, Fisher C, Clarnette R, Hallmayer J, Brooks WS, Gandy SE, Martins RN (1999) The -491AA polymorphism in the APOE gene is associated with increased plasma apoE levels in Alzheimer's disease. Neuroreport 10, 879-882.
-
(1999)
Neuroreport
, vol.10
, pp. 879-882
-
-
Laws, S.M.1
Taddei, K.2
Martins, G.3
Paton, A.4
Fisher, C.5
Clarnette, R.6
Hallmayer, J.7
Brooks, W.S.8
Gandy, S.E.9
Martins, R.N.10
-
40
-
-
0034548732
-
Genetic risk factors of sporadic Alzheimer's disease among Chinese in Taiwan
-
Hu CJ, Sung SM, Liu HC, Hsu WC, Lee LS, Lee CC, Tsai CH, Chang JG (2000) Genetic risk factors of sporadic Alzheimer's disease among Chinese in Taiwan. J Neurol Sci 181, 127-131.
-
(2000)
J Neurol Sci
, vol.181
, pp. 127-131
-
-
Hu, C.J.1
Sung, S.M.2
Liu, H.C.3
Hsu, W.C.4
Lee, L.S.5
Lee, C.C.6
Tsai, C.H.7
Chang, J.G.8
-
41
-
-
0034642230
-
Effect of APOE genotype and promoter polymorphism on risk of Alzheimer's disease
-
Wang JC, Kwon JM, Shah P, Morris JC, Goate A (2000) Effect of APOE genotype and promoter polymorphism on risk of Alzheimer's disease. Neurology 55, 1644-1649.
-
(2000)
Neurology
, vol.55
, pp. 1644-1649
-
-
Wang, J.C.1
Kwon, J.M.2
Shah, P.3
Morris, J.C.4
Goate, A.5
-
42
-
-
0034626859
-
Association of APOE promoter but not A2M polymorphisms with risk of developing Alzheimer's disease
-
Halimi G, Duplan L, Bideau C, Iniesta D, Berth́ez̀ene P, Oddoze C, Verdier JM, Michel B, Berǵe-Lefranc JL (2000) Association of APOE promoter but not A2M polymorphisms with risk of developing Alzheimer's disease. Neuroreport 11, 3599-3601.
-
(2000)
Neuroreport
, vol.11
, pp. 3599-3601
-
-
Halimi, G.1
Duplan, L.2
Bideau, C.3
Iniesta, D.4
Berth́ez̀ene, P.5
Oddoze, C.6
Verdier, J.M.7
Michel, B.8
Berǵe-Lefranc, J.L.9
-
43
-
-
0033822474
-
APOE promoter polymorphisms do not confer independent risk for Alzheimer's disease in a French population
-
Zurutuza L, Verpillat P, Raux G, Hannequin D, Puel M, Belliard S, Michon A, Pothin Y, Camuzat A, Penet C, Martin C, Brice A, Campion D, Clerget-Darpoux F, Frebourg T (2000) APOE promoter polymorphisms do not confer independent risk for Alzheimer's disease in a French population. Eur J Hum Genet 8, 713-716.
-
(2000)
Eur J Hum Genet
, vol.8
, pp. 713-716
-
-
Zurutuza, L.1
Verpillat, P.2
Raux, G.3
Hannequin, D.4
Puel, M.5
Belliard, S.6
Michon, A.7
Pothin, Y.8
Camuzat, A.9
Penet, C.10
Martin, C.11
Brice, A.12
Campion, D.13
Clerget-Darpoux, F.14
Frebourg, T.15
-
44
-
-
17144469201
-
Alzheimer's risk associated with human apolipoprotein E, alpha-2 macroglobulin and lipoprotein receptor related protein polymorphisms: Absence of genetic interactions, and modulation by gender
-
Bullido MJ, Guallar-Castilĺon P, Artiga MJ, Ramos MC, Sastre I, Aldudo J, Frank A, Coria F, Rodríguez-Artalejo F,Valdivieso F (2000) Alzheimer's risk associated with human apolipoprotein E, alpha-2 macroglobulin and lipoprotein receptor related protein polymorphisms: absence of genetic interactions, and modulation by gender. Neurosci Lett 289, 213-216.
-
(2000)
Neurosci Lett
, vol.289
, pp. 213-216
-
-
Bullido, M.J.1
Guallar-Castilĺon, P.2
Artiga, M.J.3
Ramos, M.C.4
Sastre, I.5
Aldudo, J.6
Frank, A.7
Coria, F.8
Rodríguez-Artalejo, F.9
Valdivieso, F.10
-
45
-
-
0035124734
-
Polymorphisms of the apolipoprotein e gene regulatory region and of the LDL receptor gene in late-onset Alzheimer's disease in relation to the plasma lipidic pattern
-
Scacchi R, Gambina G, Martini MC, Ruggeri M, Ferrari G, Silvestri M, Schiavon R, Corbo RM (2001) Polymorphisms of the apolipoprotein E gene regulatory region and of the LDL receptor gene in late-onset Alzheimer's disease in relation to the plasma lipidic pattern. Dement Geriatr Cogn Disord 12, 63-68.
-
(2001)
Dement Geriatr Cogn Disord
, vol.12
, pp. 63-68
-
-
Scacchi, R.1
Gambina, G.2
Martini, M.C.3
Ruggeri, M.4
Ferrari, G.5
Silvestri, M.6
Schiavon, R.7
Corbo, R.M.8
-
46
-
-
0035069881
-
Polymorphisms in the apolipoprotein e (APOE) gene in gerontopsychiatric patients
-
Zill P, Engel R, Hampel H, Behrens S, Bürger K, Padberg F, Stübner S, Möller HJ, Ackenheil M, Bondy B (2001) Polymorphisms in the apolipoprotein E (APOE) gene in gerontopsychiatric patients. Eur Arch Psychiatry Clin Neurosci 251, 24-28.
-
(2001)
Eur Arch Psychiatry Clin Neurosci
, vol.251
, pp. 24-28
-
-
Zill, P.1
Engel, R.2
Hampel, H.3
Behrens, S.4
Bürger, K.5
Padberg, F.6
Stübner, S.7
Möller, H.J.8
Ackenheil, M.9
Bondy, B.10
-
47
-
-
0035826546
-
Investigation of association of 13 polymorphisms in eight genes in southeastern African American Alzheimer disease patients as compared to age-matched controls
-
Perry RT, Collins JS, Harrell LE, Acton RT, Go RC (2001) Investigation of association of 13 polymorphisms in eight genes in southeastern African American Alzheimer disease patients as compared to age-matched controls. Am J Med Genet 105, 332-342.
-
(2001)
Am J Med Genet
, vol.105
, pp. 332-342
-
-
Perry, R.T.1
Collins, J.S.2
Harrell, L.E.3
Acton, R.T.4
Go, R.C.5
-
48
-
-
0035947212
-
The -491 TT apolipoprotein e promoter polymorphism is associated with reduced risk for sporadic Alzheimer's disease
-
Alvarez-Arcaya A, Combarros O, Llorca J, Śanchez-Guerra M, Berciano J, Ferńandez-Luna JL (2001) The -491 TT apolipoprotein E promoter polymorphism is associated with reduced risk for sporadic Alzheimer's disease. Neurosci Lett 304, 204-208.
-
(2001)
Neurosci Lett
, vol.304
, pp. 204-208
-
-
Alvarez-Arcaya, A.1
Combarros, O.2
Llorca, J.3
Śanchez-Guerra, M.4
Berciano, J.5
Ferńandez-Luna, J.L.6
-
49
-
-
0037025116
-
The Th1/E47cs-G apolipo- protein e (APOE) promoter allele is a risk factor for Alzheimer disease of very later onset
-
Beyer K, Lao JI, Ǵomez M, Riutort N, Latorre P, Mate JL, Ariza A (2002) The Th1/E47cs-G apolipo- protein E (APOE) promoter allele is a risk factor for Alzheimer disease of very later onset. Neurosci Lett 326, 187-190.
-
(2002)
Neurosci Lett
, vol.326
, pp. 187-190
-
-
Beyer, K.1
Lao, J.I.2
Ǵomez, M.3
Riutort, N.4
Latorre, P.5
Mate, J.L.6
Ariza, A.7
-
50
-
-
0036382942
-
Variation at the APOE -491 promoter locus is associated with altered brain levels of apolipoprotein e
-
Laws SM, Hone E, Taddei K, Harper C, Dean B, McClean C, Masters C, Lautenschlager N, Gandy SE, Martins RN (2002) Variation at the APOE -491 promoter locus is associated with altered brain levels of apolipoprotein E. Mol Psychiatry 7, 886-890.
-
(2002)
Mol Psychiatry
, vol.7
, pp. 886-890
-
-
Laws, S.M.1
Hone, E.2
Taddei, K.3
Harper, C.4
Dean, B.5
McClean, C.6
Masters, C.7
Lautenschlager, N.8
Gandy, S.E.9
Martins, R.N.10
-
51
-
-
0036453105
-
Genetic analysis of vascular factors in Alzheimer's disease
-
Wakutani Y, Kowa H, Kusumi M, Yamagata K, Wada-Isoe K, Adachi Y, Takeshima T, Urakami K, Nakashima K (2002) Genetic analysis of vascular factors in Alzheimer's disease. Ann N Y Acad Sci 977, 232-238.
-
(2002)
Ann N y Acad Sci
, vol.977
, pp. 232-238
-
-
Wakutani, Y.1
Kowa, H.2
Kusumi, M.3
Yamagata, K.4
Wada-Isoe, K.5
Adachi, Y.6
Takeshima, T.7
Urakami, K.8
Nakashima, K.9
-
52
-
-
18444370838
-
Effect of the APOE- 491A/T promoter polymorphism on apolipoprotein e levels and risk of Alzheimer disease: The Rotterdam Study
-
Roks G, Cruts M, Houwing-Duistermaat JJ, Dermaut B, Serneels S, Havekes LM, Hofman A, Breteler MM, Van Broeckhoven C, van Duijn CM (2002) Effect of the APOE- 491A/T promoter polymorphism on apolipoprotein E levels and risk of Alzheimer disease: The Rotterdam Study. Am J Med Genet 114, 570-573.
-
(2002)
Am J Med Genet
, vol.114
, pp. 570-573
-
-
Roks, G.1
Cruts, M.2
Houwing-Duistermaat, J.J.3
Dermaut, B.4
Serneels, S.5
Havekes, L.M.6
Hofman, A.7
Breteler, M.M.8
Van Broeckhoven, C.9
Van Duijn, C.M.10
-
53
-
-
0037497125
-
A study on the relation between the apolipoprotein e promoter -427C/T polymorphism and Alzheimer's disease
-
Tang GM, Zhang MY, Jiang SD, Qian YP,Wang DX (2003) A study on the relation between the apolipoprotein E promoter -427C/T polymorphism and Alzheimer's disease. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 20, 244-246.
-
(2003)
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
, vol.20
, pp. 244-246
-
-
Tang, G.M.1
Zhang, M.Y.2
Jiang, S.D.3
Qian Ypwang, D.X.4
-
54
-
-
0142075287
-
Apolipoprotein e -491 promoter polymorphism is an independent risk factor for Alzheimer's disease in the Chinese population
-
Yang JD, Feng GY, Zhang J, Cheung J, St Clair D, He L, Ichimura K (2003) Apolipoprotein E -491 promoter polymorphism is an independent risk factor for Alzheimer's disease in the Chinese population. Neurosci Lett 350, 25-28.
-
(2003)
Neurosci Lett
, vol.350
, pp. 25-28
-
-
Yang, J.D.1
Feng, G.Y.2
Zhang, J.3
Cheung, J.4
St Clair, D.5
He, L.6
Ichimura, K.7
-
55
-
-
0142091468
-
Haplogroup analysis of the risk associated with APOE promoter polymorphisms (-219T/G, -491A/T and -427T/C) in Colombian Alzheimer's disease patients
-
Parra-Bonilla G, Arboleda G, Yunis J, Solano E, Pardo R, Arango G, Hedmont D, Arboleda H (2003) Haplogroup analysis of the risk associated with APOE promoter polymorphisms (-219T/G, -491A/T and -427T/C) in Colombian Alzheimer's disease patients. Neurosci Lett 349, 159-162.
-
(2003)
Neurosci Lett
, vol.349
, pp. 159-162
-
-
Parra-Bonilla, G.1
Arboleda, G.2
Yunis, J.3
Solano, E.4
Pardo, R.5
Arango, G.6
Hedmont, D.7
Arboleda, H.8
-
56
-
-
3042701772
-
APOE promoter, ACEI and CYP46 polymorphisms and ?-amyloid in Alzheimer's disease
-
Chalmers KA, Culpan D, Kehoe PG,Wilcock GK, Hughes A, Love S (2004) APOE promoter, ACEI and CYP46 polymorphisms and ?-amyloid in Alzheimer's disease. Neuroreport 15, 95-98.
-
(2004)
Neuroreport
, vol.15
, pp. 95-98
-
-
Chalmers, K.A.1
Culpan, D.2
Kehoe Pgwilcock, G.K.3
Hughes, A.4
Love, S.5
-
57
-
-
19944433115
-
Comprehensive association analysis of APOE regulatory region polymorphisms in Alzheimer disease
-
Nicodemus KK, Stenger JE, Schmechel DE, Welsh-Bohmer KA, Saunders AM, Roses AD, Gilbert JR, Vance JM, Haines JL, Pericak-Vance MA, Martin ER (2004) Comprehensive association analysis of APOE regulatory region polymorphisms in Alzheimer disease. Neurogenetics 5, 201-208.
-
(2004)
Neurogenetics
, vol.5
, pp. 201-208
-
-
Nicodemus, K.K.1
Stenger, J.E.2
Schmechel, D.E.3
Welsh-Bohmer, K.A.4
Saunders, A.M.5
Roses, A.D.6
Gilbert, J.R.7
Vance, J.M.8
Haines, J.L.9
Pericak-Vance, M.A.10
Martin, E.R.11
-
58
-
-
23944523570
-
ApoE - 491A/T promoter polymorphism is not an independent risk factor, but associated with the epsilon4 allele in Hungarian Alzheimer's dementia population
-
Juh́asz A, Palot́as A, Janka Z, Rimańoczy A, Palot́as M, B́odi N, Boda K, Zana M, Vincze G, Ḱalḿan J (2005) ApoE - 491A/T promoter polymorphism is not an independent risk factor, but associated with the epsilon4 allele in Hungarian Alzheimer's dementia population. Neurochem Res 30, 591-596.
-
(2005)
Neurochem Res
, vol.30
, pp. 591-596
-
-
Juh́asz, A.1
Palot́as, A.2
Janka, Z.3
Rimańoczy, A.4
Palot́as, M.5
B́odi, N.6
Boda, K.7
Zana, M.8
Vincze, G.9
Ḱalḿan, J.10
-
59
-
-
33645746696
-
Apolipo- protein gene E4 allele promoter polymorphisms as risk factors for Alzheimer's disease
-
Parker GR, Cathcart HM, Huang R, Lanham IS, Corder EH, Poduslo SE (2005) Apolipo- protein gene E4 allele promoter polymorphisms as risk factors for Alzheimer's disease. Psychiatr Genet 15, 271-275.
-
(2005)
Psychiatr Genet
, vol.15
, pp. 271-275
-
-
Parker, G.R.1
Cathcart, H.M.2
Huang, R.3
Lanham, I.S.4
Corder, E.H.5
Poduslo, S.E.6
-
60
-
-
34447559923
-
Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants
-
Grupe A, Abraham R, Li Y, Rowland C, Hollingworth P, Morgan A, Jehu L, Segurado R, Stone D, Schadt E, Karnoub M, Nowotny P, Tacey K, Catanese J, Sninsky J, Brayne C, Rubinsztein D, Gill M, Lawlor B, Lovestone S, Holmans P, O'Donovan M, Morris JC, Thal L, Goate A, Owen MJ, Williams J (2007). Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants. Hum Mol Genet 16, 865-873.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 865-873
-
-
Grupe, A.1
Abraham, R.2
Li, Y.3
Rowland, C.4
Hollingworth, P.5
Morgan, A.6
Jehu, L.7
Segurado, R.8
Stone, D.9
Schadt, E.10
Karnoub, M.11
Nowotny, P.12
Tacey, K.13
Catanese, J.14
Sninsky, J.15
Brayne, C.16
Rubinsztein, D.17
Gill, M.18
Lawlor, B.19
Lovestone, S.20
Holmans, P.21
O'Donovan, M.22
Morris, J.C.23
Thal, L.24
Goate, A.25
Owen, M.J.26
Williams, J.27
more..
-
61
-
-
50349083512
-
Apolipoprotein e promoter polymorphisms (- 491A/T and -427T/C) and Alzheimer's disease: No evidence of association in the Irish population
-
Lynch CA, Brazil J, Cullen B, Coakley D, Gill M, Lawlor BA, Hawi Z (2008) Apolipoprotein E promoter polymorphisms (- 491A/T and -427T/C) and Alzheimer's disease: no evidence of association in the Irish population. Ir J Med Sci 177, 29-33.
-
(2008)
Ir J Med Sci
, vol.177
, pp. 29-33
-
-
Lynch, C.A.1
Brazil, J.2
Cullen, B.3
Coakley, D.4
Gill, M.5
Lawlor, B.A.6
Hawi, Z.7
-
62
-
-
43249128655
-
Polymorphisms of APOE and LRP genes in Brazilian individuals with Alzheimer disease
-
Bahia VS, Kok F, Marie SN, Shinjo SO, Caramelli P, Nitrini R (2008) Polymorphisms of APOE and LRP genes in Brazilian individuals with Alzheimer disease. Alzheimer Dis Assoc Disord 22, 61-65.
-
(2008)
Alzheimer Dis Assoc Disord
, vol.22
, pp. 61-65
-
-
Bahia, V.S.1
Kok, F.2
Marie, S.N.3
Shinjo, S.O.4
Caramelli, P.5
Nitrini, R.6
-
63
-
-
61849090884
-
The role of the -427T/C apolipoprotein e promoter polymorphism in the pathogenesis of Alzheimer's disease, vascular dementia and mixed dementia
-
Trebunov́a M, Slab́a E, Habalov́a V, Gdovinov́a Z (2009) The role of the -427T/C apolipoprotein E promoter polymorphism in the pathogenesis of Alzheimer's disease, vascular dementia and mixed dementia. Neural Transm 116, 339-344.
-
(2009)
Neural Transm
, vol.116
, pp. 339-344
-
-
Trebunov́a, M.1
Slab́a, E.2
Habalov́a, V.3
Gdovinov́a, Z.4
-
64
-
-
67649188778
-
The complex interaction between APOE promoter and AD: An Italian case-control study
-
Bizzarro A, Seripa D, Acciarri A, Matera MG, Pilotto A, Tiziano FD, Brahe C, Masullo C (2009) The complex interaction between APOE promoter and AD: an Italian case-control study. Eur J Hum Genet 17, 938-945.
-
(2009)
Eur J Hum Genet
, vol.17
, pp. 938-945
-
-
Bizzarro, A.1
Seripa, D.2
Acciarri, A.3
Matera, M.G.4
Pilotto, A.5
Tiziano, F.D.6
Brahe, C.7
Masullo, C.8
-
65
-
-
59149084048
-
Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease
-
Carrasquillo MM, Zou F, Pankratz VS, Wilcox SL, Ma L, Walker LP, Younkin SG, Younkin CS, Younkin LH, Bisceglio GD, Ertekin-Taner N, Crook JE, Dickson DW, Petersen RC, Graff-Radford NR, Younkin SG (2009) Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease. Nat Genet 41, 192-198.
-
(2009)
Nat Genet
, vol.41
, pp. 192-198
-
-
Carrasquillo, M.M.1
Zou, F.2
Pankratz, V.S.3
Wilcox, S.L.4
Ma, L.5
Walker, L.P.6
Younkin, S.G.7
Younkin, C.S.8
Younkin, L.H.9
Bisceglio, G.D.10
Ertekin-Taner, N.11
Crook, J.E.12
Dickson, D.W.13
Petersen, R.C.14
Graff-Radford, N.R.15
Younkin, S.G.16
-
66
-
-
17844365867
-
A method for meta-analysis of molecular association studies
-
Thakkinstian A, McElduff P, D'Este C, Duffy D, Attia J (2005) A method for meta-analysis of molecular association studies. Stat Med 24, 1291-1306.
-
(2005)
Stat Med
, vol.24
, pp. 1291-1306
-
-
Thakkinstian, A.1
McElduff, P.2
D'Este, C.3
Duffy, D.4
Attia, J.5
-
67
-
-
0026652019
-
Cumulative meta-analysis of therapeutic trials for myocardial infarction
-
Lau J, Antman Em, Jimenez-Silva J,Kupelnick B, Mosteller F, Chalmers TC (1992) Cumulative meta-analysis of therapeutic trials for myocardial infarction. N Engl J Med 327, 248-254.
-
(1992)
N Engl J Med
, vol.327
, pp. 248-254
-
-
Lau, J.1
Antman, E.M.2
Jimenez-Silva, J.3
Kupelnick, B.4
Mosteller, F.5
Chalmers, T.C.6
-
68
-
-
33845892752
-
Systematic meta-analyses of Alzheimer disease genetic association studies: The AlzGene database
-
Bertram L, McQueen MB, Mullin K, Blacker D, Tanzi RE (2007) Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. Nat Genet 39, 17-23.
-
(2007)
Nat Genet
, vol.39
, pp. 17-23
-
-
Bertram, L.1
McQueen, M.B.2
Mullin, K.3
Blacker, D.4
Tanzi, R.E.5
|