Apolipoprotein E promoter polymorphism and sporadic Alzheimer's disease in a Japanese population

Neuroscience Letters

Volumn 259, Issue 1, 1999, Pages 56-58

  Toji, Hiromasa ^a   Maruyama, Hirofumi ^a   Sasaki, Ken ^b   Nakamura, Shigenobu ^a   Kawakami, Hideshi ^a  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

^b Kinoko Espoir Hospital   (Japan)

Author keywords

Alzheimer's disease; Apolipoprotein E promoter polymorphism; Ethnic background; Risk factor

Indexed keywords

APOLIPOPROTEIN E;

AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; ETHNIC GROUP; FEMALE; GENOTYPE; HOMOZYGOSITY; HUMAN; HUMAN CELL; JAPAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; RISK FACTOR;

AGE OF ONSET; AGED; ALZHEIMER DISEASE; APOLIPOPROTEINS E; ASIAN CONTINENTAL ANCESTRY GROUP; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HUMANS; JAPAN; MALE; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); RISK FACTORS; SPAIN;

EID: 0033521635     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(98)00855-6     Document Type: Article

References (5)

1. Bullido M.J., Artiga M.J., Recuero M., Sastre I., García M.A., Aldudo J., Lendon C., Han S.W., Moris J.C., Frank A., Vázquez J., Goate A., Valdivieso F. A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia. Nat. Genet. 18:1998;69-71.
2. Corder E.H., Saunders A.M., Strittmatter W.J., Schmechel D.E., Gaskell P.C., Small G.W., Roses A.D., Haines J.L., Pericak-Vance M.A. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science. 261:1993;921-923.
3. Saunders A.M., Strittmatter W.J., Schmechel D., St. George-Hyslop P.H., Pericak-Vance M.A., Joo S.H., Rosi B.L., Gusella J.F., Crapper-MacLachlan D.R., Alberts M.J., Hulette C., Crain B., Goldgaber D., Roses A.D. Association of apolipoprotein E allele e4 with late-onset familial and sporadic Alzheimer's disease. Neurology. 43:1993;1467-1472.
4. Toji H., Kawakami H., Kawarai T., Nakayama T., Komure O., Kuno S., Nakamura S. No association between apolipoprotein E alleles and olivopontocerebellar atrophy. J. Neurol. Sci. 158:1998;110-112.
5. Yoshizawa T., Yamakawa-Kobayashi K., Komatsuzaki Y., Arinami T., Oguni E., Mizusawa H., Shoji S., Hamaguchi H. Dose-dependent association of apolipoprotein E allele ε4 with late-onset, sporadic Alzheimer's disease. Ann. Neurol. 36:1994;656-659.