The role of the -427T/C apolipoprotein e promoter polymorphism in the pathogenesis of Alzheimer's disease, vascular dementia and mixed dementia

Journal of Neural Transmission

Volumn 116, Issue 3, 2009, Pages 339-344

  Trebuňová, Marianna ^a   Slabá, Eva ^a   Habalová, Viera ^a   Gdovinová, Zuzana ^a  

^a P J AFÁRIK UNIVERSITY   (Slovakia)

Author keywords

Alzheimer's disease; APOE; Mixed dementia; Promoter polymorphisms 427T C; Vascular dementia

Indexed keywords

APOLIPOPROTEIN E4;

ADULT; AGED; ALLELE; ALZHEIMER DISEASE; APOE GENE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE INTERACTION; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MIXED DEPRESSION AND DEMENTIA; MULTIINFARCT DEMENTIA; PATHOGENESIS; POLYMORPHIC LOCUS; PRIORITY JOURNAL; PROMOTER REGION;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; APOLIPOPROTEINS E; DEMENTIA; DEMENTIA, VASCULAR; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; RISK FACTORS; SEX FACTORS;

EID: 61849090884     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-008-0178-5     Document Type: Article

References (25)

1. MJ Artiga MJ Bullido A Frank I Sastre M Recuero MA Garcia CL Lendon SW Han JC Morris J Vazquez A Goate F Valdivieso 1998 Risk for Alzheimer's disease correlates with transcriptional activity of the APOE gene Hum Mol Gen 12 1887 1892
2. H Aybek F Ercan D Aslan T Sahiner 2007 Determination of malondialdehyde, reduced glutathione levels and APOE4 allele frequency in late-onset Alzheimer's disease in Denilzy, Turkay Clin Biochem 40 172 176
3. MJ Bullido MJ Artiga M Recuero I Sastre M Angel G Jesus A Corinne L Sang W Han JC Morris A Frank J Vazquez A Goate F Valdivieso 1998 A polymorfiphism in the regulatory region of APOE associated with risk for Alzheimer's dementia Nat Genet 18 69 71
4. J Chapman J Estupinan A Ascherov G Goldfarb 1996 A simple and efficient method for apolipoprotein E genotype determination Neurology 46 1484 1485
5. L Cibickova V Palicka 2005 Alzheimerova choroba, cholesterol a apolipoprotein E-nové súvislosti Klin Biochem Metab 13 127 130
6. EH Corder AM Saunders WJ Strittmatter DE Schmechel PC Gaskell GW Small AD Roses JL Haines MA Pericak-Vance 1993 Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families Science 261 921 923
7. Y Davidson L Gibbons A Pritchard J Hardicre J Wren C Stopford C Julien J Thomson A Payton SM Pickeboring-Brown N Pendleton MA Horan A Burns N Purandare CL Lendon D Neary JS Snowden DM Mann 2007 Apolipoprotein E epsilon e allele frequency and age at onset of Alzheimer's disease Dement Geriatr Cogn Disord 23 60 66
8. M Emi LL Wu MA Robertson RL Myers RA Hegele RR Wiliams R White JM Lalouel 1988 Genotyping and sequence analysis of apolipoprotein E isoforms Genomics 3 373 379
9. S Itabashi H Arai S Higuchi H Sasaki JQ Trojanowski 1996 ApoE ε4 allele in Alzheimer's dementias Lancet 348 960 961
10. AF Jorm KA Mather P Butterworth KJ Anstey H Christensen S Eastea 2007 APOE genotype and cognitive functioning in a large age-stratified population sample Neuropsychology 21 1 8
11. R Kalaria 2002 Similarities between Alzheimer's disease and vascular dementia J Neurol Sci 203-204 29 34
12. AD Korczyn 2005 The underdiagnosis of the vascular contribution to dementia J Neurol Sci 229-230 3 6
13. JC Lambert C Berr F Pasquier A Delacourte B Frigard D Cottel J Perez-Tur V Mouroux M Mohr D Cecyre D Galasko C Lendon J Poirier J Hardy D Mann P Amouyel MC Chartier-Harlin 1998 Pronounced impact of Th1/E47cs mutation compared with -491AT mutation on neural APOE gene expression and risk of developing Alzheimer's disease Hum Mol Genet 7 1511 1516
14. SM Laws K Tadde G Martins A Paton Ch Fisher R Clarnette J Hallmayer W Brooks SE Gandy RN Martins 1999 The -491 AA polymorphism in the APOE gene is associated with increased plasma apoE levels in Alzheimer's disease NeuroReport 10 879 882
15. CA Lynch J Brazil B Cullen D Coakley M Gill BA Lawlor Z Hawi 2008 Apolipoprotein E promoter polymorphism (-491A/T and -427 T/C) and Alzheimer's disease: no evidence of association in the Irish population Irish J Med Sci 177 29 33
16. AJ Myers AM Goate 2001 The genetics of late-onset Alzheimer's disease Curr Opin Neurol 14 433 440
17. M Novák 1997 Alzheimerova choroba Bratisl A Lekar Listy 6 303 314
18. GR Parker HM Cathcart R Huang IS Lanham EH Corder SE Podulso 2005 Apolipoprotein E E4 allele promoter polymorphisms as risk factor for Alzheimer's disease Psychiatric Genet 15 271 275
19. T Pirttila T Lehtimaki J Rinne K Mattila H Frey T Nikkari 1996 The frequency of apolipoprotein E4 allele is not increased in patients with probable vascular dementia Acta Neurol Scand 93 352 354
20. GW Rebeck TT Perl HL West P Sodhi LA Lipsitz BT Hyman 1994 Reduced apolipoprotein ε4 allele frequency in the oldest old Alzheimer's patients and cognitively normal individuals Neurology 44 1513 1516
21. AM Saunders C Hulette KA Welsh-Bohmer DE Schmechel B Crain JR Burke MJ Alberts WJ Strittmatter JCS Breitner C Rosenberg SV Scott PC Gaskell MA Pericak-Vance AD Roses 1996 Specificity, sensitivity and predictive value of apolipoprotein E genotyping for Alzheimer's disease Lancet 348 90 93
22. R Scacchi G Gambina MC Martini M Ruggeri G Ferrari M Silvestri R Schiavon RM Corbo 2001 Polymorphism of the apolipoprotein E gene regulatory region and of the LDL receptor gene in late-onset Alzheimer's disease in relation to the plasma lipic pattern Dement Geriatr Cognit Disord 12 63 68
23. I Skoog C Hesse O Aevarson S Landahl J Wahlstrom P Fredman K Blennow 1998 A population study of apoE genotype at the age of 85: relation to dementia, cerebrovascular disease, and mortality J Neurol Neurosurg Psychiatry 64 37 43
24. JC Wang MD Kwon JC Shah MD Morris A Goate 2000 Effect of APOE genotype and promoter polymorphism on risk of Alzheimer's disease Neurology 55 1644 1649
25. H Wehr M Bednarska-Makaruk W Lojkowska A Graban D Hoffman-Zacharska A Kuczynska-Zardzewialy J Mrugala M Rodo A Bochynska A Sulek D Ryglewicz 2006 Differences in risk factors for dementia with neurodegenerative traits and for vascular dementia Dement Geriatr Cognit Disord 22 1 7