메뉴 건너뛰기




Volumn 19, Issue 4, 2010, Pages 1359-1370

Simple in vitro assays to identify amyloid-β aggregation blockers for Alzheimer's disease therapy

Author keywords

Blueberry; Cinnamon; Congo red; Epigallocatechin gallate; Garlic; Ginger; Resveratrol; Rhubarb; S diclofenac; Senile plaques; Spirulina; Turmeric

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; BLUEBERRY EXTRACT; CARYOPHYLLENE; CINNAMON EXTRACT; CURCUMIN; DICLOFENAC; EMODIN; EPIGALLOCATECHIN GALLATE; GARLIC EXTRACT; GINGER EXTRACT; GINKGOLIDE A; GLUCOSE PENTAGALLATE; HOMOTAURINE; INOSITOL; INOSITOL DERIVATIVE; RESVERATROL; RHAMNOSE; RHEIN; RHUBARB EXTRACT; TURMERIC; VALPROIC ACID;

EID: 77950345575     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2010-1331     Document Type: Article
Times cited : (55)

References (48)
  • 1
    • 67651180986 scopus 로고    scopus 로고
    • The amyloid hypothesis for Alzheimer's disease: A critical reappraisal
    • Hardy J (2009) The amyloid hypothesis for Alzheimer's disease: a critical reappraisal. J Neurochem 110, 1129-1134.
    • (2009) J Neurochem , vol.110 , pp. 1129-1134
    • Hardy, J.1
  • 2
    • 13844255273 scopus 로고    scopus 로고
    • Molecular biology and genetics of Alzheimer's disease
    • St George-Hyslop PH, Petit A (2005) Molecular biology and genetics of Alzheimer's disease. Comptes Rendus Biologies 328, 119-130.
    • (2005) Comptes Rendus Biologies , vol.328 , pp. 119-130
    • St George-Hyslop, P.H.1    Petit, A.2
  • 3
    • 0034971707 scopus 로고    scopus 로고
    • Missense and splice site mutations in tau associated with FTDP-17: Multiple pathogenic mechanisms
    • Hutton M (2001) Missense and splice site mutations in tau associated with FTDP-17: Multiple pathogenic mechanisms. Neurology 56, S21-S25.
    • (2001) Neurology , vol.56
    • Hutton, M.1
  • 4
    • 34547464672 scopus 로고    scopus 로고
    • Genetically augmenting tau levels does not modulate the onset or progression ofAbeta pathology in transgenic mice
    • Oddo S, Caccamo A, Cheng D, Jouleh B, Torp R, LaFerla FM (2007) Genetically augmenting tau levels does not modulate the onset or progression ofAbeta pathology in transgenic mice. J Neurochem 102, 1053-1063.
    • (2007) J Neurochem , vol.102 , pp. 1053-1063
    • Oddo, S.1    Caccamo, A.2    Cheng, D.3    Jouleh, B.4    Torp, R.5    Laferla, F.M.6
  • 6
    • 69849108778 scopus 로고    scopus 로고
    • Beta- Amyloid as a molecular therapeutic target in Alzheimer's disease
    • Adlard PA, James SA, Bush AI, Masters CL (2009) beta- Amyloid as a molecular therapeutic target in Alzheimer's disease. Drugs Today (Barc) 45, 293-304.
    • (2009) Drugs Today (Barc) , vol.45 , pp. 293-304
    • Adlard, P.A.1    James, S.A.2    Bush, A.I.3    Masters, C.L.4
  • 7
    • 0030801497 scopus 로고    scopus 로고
    • Inhibitors of A beta peptide aggregation as potential anti-Alzheimer agents
    • Bandiera T, Lansen J, Post C, Varasi M (1997) Inhibitors of A beta peptide aggregation as potential anti-Alzheimer agents. Curr Med Chem 4, 159-170.
    • (1997) Curr Med Chem , vol.4 , pp. 159-170
    • Bandiera, T.1    Lansen, J.2    Post, C.3    Varasi, M.4
  • 8
    • 33745758083 scopus 로고    scopus 로고
    • Inhibition of protein misfolding and aggregation by small rationally-designed peptides
    • Estrada LD, Soto C (2006) Inhibition of protein misfolding and aggregation by small rationally-designed peptides. Curr Pharm Des 12, 2557-2567.
    • (2006) Curr Pharm des , vol.12 , pp. 2557-2567
    • Estrada, L.D.1    Soto, C.2
  • 9
    • 60549107033 scopus 로고    scopus 로고
    • A specific enzyme-linked immunosorbent assay for measuring beta-amyloid protein oligomers in human plasma and brain tissue of patients with Alzheimer disease
    • Xia W, Yang T, Shankar G, Smith IM, Shen Y, Walsh DM, Selkoe DJ (2009) A specific enzyme-linked immunosorbent assay for measuring beta-amyloid protein oligomers in human plasma and brain tissue of patients with Alzheimer disease. Arch Neurol 66, 190-199.
    • (2009) Arch Neurol , vol.66 , pp. 190-199
    • Xia, W.1    Yang, T.2    Shankar, G.3    Smith, I.M.4    Shen, Y.5    Walsh, D.M.6    Selkoe, D.J.7
  • 11
    • 67349175242 scopus 로고    scopus 로고
    • Comparison of Abeta levels in the brain of familial and sporadic Alzheimer's disease
    • Hellstrom-Lindahl E, Viitanen M, Marutle A (2009) Comparison of Abeta levels in the brain of familial and sporadic Alzheimer's disease. Neurochem Int 55, 243-252.
    • (2009) Neurochem Int , vol.55 , pp. 243-252
    • Hellstrom-Lindahl, E.1    Viitanen, M.2    Marutle, A.3
  • 13
    • 2942706109 scopus 로고    scopus 로고
    • SARS corona virus peptides recognized by antibodies in the sera of convalescent cases
    • Guo JP, Petric M, Campbell W, McGeer PL (2004) SARS corona virus peptides recognized by antibodies in the sera of convalescent cases. Virology 324, 251-256.
    • (2004) Virology , vol.324 , pp. 251-256
    • Guo, J.P.1    Petric, M.2    Campbell, W.3    McGeer, P.L.4
  • 15
    • 0033596944 scopus 로고    scopus 로고
    • Recognition sequence design for peptidyl modulators of beta-amyloid aggregation and toxicity
    • Pallitto MM, Ghanta J, Heinzelman P, Kiessling LL, Murphy RM (1999) Recognition sequence design for peptidyl modulators of beta-amyloid aggregation and toxicity. Biochemistry 38, 3570-3578.
    • (1999) Biochemistry , vol.38 , pp. 3570-3578
    • Pallitto, M.M.1    Ghanta, J.2    Heinzelman, P.3    Kiessling, L.L.4    Murphy, R.M.5
  • 17
    • 2642578354 scopus 로고    scopus 로고
    • Single chain variable fragments against beta-amyloid (Abeta) can inhibit Abeta aggregation and prevent abeta-induced neurotoxicity
    • Liu R, Yuan B, Emadi S, Zameer A, Schulz P, McAllister C, Lyubchenko Y, Goud G, Sierks MR (2004) Single chain variable fragments against beta-amyloid (Abeta) can inhibit Abeta aggregation and prevent abeta-induced neurotoxicity. Biochemistry 43, 6959-6967.
    • (2004) Biochemistry , vol.43 , pp. 6959-6967
    • Liu, R.1    Yuan, B.2    Emadi, S.3    Zameer, A.4    Schulz, P.5    McAllister, C.6    Lyubchenko, Y.7    Goud, G.8    Sierks, M.R.9
  • 21
    • 37849037631 scopus 로고    scopus 로고
    • The hydrogen sulphide-releasing derivative of diclofenac protects against ischaemia-reperfusion injury in the isolated rabbit heart
    • Rossoni G, Sparatore A, Tazzari V, Manfredi B, Del Soldato P, Berti F (2008) The hydrogen sulphide-releasing derivative of diclofenac protects against ischaemia-reperfusion injury in the isolated rabbit heart. Br J Pharmacol 153, 100-109.
    • (2008) Br J Pharmacol , vol.153 , pp. 100-109
    • Rossoni, G.1    Sparatore, A.2    Tazzari, V.3    Manfredi, B.4    Del Soldato, P.5    Berti, F.6
  • 22
    • 73449101844 scopus 로고    scopus 로고
    • Hydrogen sulfide-releasing NSAIDs attenuate neuroinflammation induced by microglial and astrocytic activation
    • Lee M, Sparatore A, Del Soldato P, McGeer E, McGeer PL (2010) Hydrogen sulfide-releasing NSAIDs attenuate neuroinflammation induced by microglial and astrocytic activation. Glia 58, 103-113.
    • (2010) Glia , vol.58 , pp. 103-113
    • Lee, M.1    Sparatore, A.2    Del Soldato, P.3    McGeer, E.4    McGeer, P.L.5
  • 24
    • 33845192482 scopus 로고    scopus 로고
    • Congo red and protein aggregation in neurodegenerative diseases
    • Frid P, Anisimov SV, Popovic N (2007) Congo red and protein aggregation in neurodegenerative diseases. Brain Res Rev 53, 135-160.
    • (2007) Brain Res Rev , vol.53 , pp. 135-160
    • Frid, P.1    Anisimov, S.V.2    Popovic, N.3
  • 25
    • 34248146970 scopus 로고    scopus 로고
    • Effect of resveratrol on antioxidant enzyme activities in the brain of healthy rat
    • Mokni M, Elkahoui S, Limam F, Amri M, Aouani E (2007) Effect of resveratrol on antioxidant enzyme activities in the brain of healthy rat. Neurochem Res 32, 981-987.
    • (2007) Neurochem Res , vol.32 , pp. 981-987
    • Mokni, M.1    Elkahoui, S.2    Limam, F.3    Amri, M.4    Aouani, E.5
  • 26
    • 27844497059 scopus 로고    scopus 로고
    • Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides
    • Marambaud P, Zhao H, Davies P (2005) Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides. J Biol Chem 280, 37377-37382.
    • (2005) J Biol Chem , vol.280 , pp. 37377-37382
    • Marambaud, P.1    Zhao, H.2    Davies, P.3
  • 27
    • 60249098801 scopus 로고    scopus 로고
    • Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease
    • Karuppagounder SS, Pinto JT, Xu H, Chen HL, Beal MF, Gibson GE (2009) Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease. Neurochem Int 54, 111-118.
    • (2009) Neurochem Int , vol.54 , pp. 111-118
    • Karuppagounder, S.S.1    Pinto, J.T.2    Xu, H.3    Chen, H.L.4    Beal, M.F.5    Gibson, G.E.6
  • 29
    • 34249867410 scopus 로고    scopus 로고
    • Properties of scyllo-inositol as a therapeutic treatment of AD-like pathology
    • Fenili D, Brown M, Rappaport R, McLaurin J (2007) Properties of scyllo-inositol as a therapeutic treatment of AD-like pathology. J Mol Med 85, 603-611.
    • (2007) J Mol Med , vol.85 , pp. 603-611
    • Fenili, D.1    Brown, M.2    Rappaport, R.3    McLaurin, J.4
  • 31
    • 0942264280 scopus 로고    scopus 로고
    • Immunomodulating components from Chinese medicines
    • Li XY (2000) Immunomodulating components from Chinese medicines. Pharm Biol 38, 33-40 Suppl. S.
    • (2000) Pharm Biol , vol.38 , Issue.SUPPL. S , pp. 33-40
    • Li, X.Y.1
  • 33
    • 23044479821 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) inhibits constitutive NF-kappa B activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma
    • Shishodia S, Amin HM, Lai R, Aggarwal BB (2005) Curcumin (diferuloylmethane) inhibits constitutive NF-kappa B activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma. Biochem Pharmacol 70, 700-713.
    • (2005) Biochem Pharmacol , vol.70 , pp. 700-713
    • Shishodia, S.1    Amin, H.M.2    Lai, R.3    Aggarwal, B.B.4
  • 35
    • 1542364225 scopus 로고    scopus 로고
    • Curcumin has potent anti-amyloidogenic effects for Alzheimer's betaamyloid fibrils in vitro
    • Ono K, Hasegawa K, Naiki H, Yamada M (2004) Curcumin has potent anti-amyloidogenic effects for Alzheimer's betaamyloid fibrils in vitro. J Neurosci Res 75, 742-750.
    • (2004) J Neurosci Res , vol.75 , pp. 742-750
    • Ono, K.1    Hasegawa, K.2    Naiki, H.3    Yamada, M.4
  • 36
    • 34247590127 scopus 로고    scopus 로고
    • Alzheimer's disease drug discovery from herbs: Neuroprotectivity from beta-amyloid (1-42) insult
    • Kim DSHL, Kim JY, Han YS (2007) Alzheimer's disease drug discovery from herbs: Neuroprotectivity from beta-amyloid (1-42) insult. J Altern Complement Med 13, 333-340.
    • (2007) J Altern Complement Med , vol.13 , pp. 333-340
    • Dshl, K.1    Kim, J.Y.2    Han, Y.S.3
  • 37
    • 0036741254 scopus 로고    scopus 로고
    • Discovery of natural products from Curcuma longa that protect cells from beta-amyloid insult: A drug discovery effort against Alzheimer's disease
    • Park SY, Kim DSHL (2002) Discovery of natural products from Curcuma longa that protect cells from beta-amyloid insult: A drug discovery effort against Alzheimer's disease. J Nat Prod 65, 1227-1231.
    • (2002) J Nat Prod , vol.65 , pp. 1227-1231
    • Park, S.Y.1    Dshl, K.2
  • 39
    • 0032789312 scopus 로고    scopus 로고
    • Psychotropic drug treatment of behavioral disorders in dementia
    • Stoppe G, Staedt J (1999) Psychotropic drug treatment of behavioral disorders in dementia. Z Gerontol Geriatr 32, 153-158.
    • (1999) Z Gerontol Geriatr , vol.32 , pp. 153-158
    • Stoppe, G.1    Staedt, J.2
  • 40
    • 33751234808 scopus 로고    scopus 로고
    • Protective effect of rhubarb derivatives on amyloid beta (1-42) peptide-induced apoptosis in IMR-32 cells: A case of nutrigenomic
    • Misiti F, Sampaolese B, Mezzogori D, Orsini F, Pezzotti M, Giardina B, Clementi ME (2006) Protective effect of rhubarb derivatives on amyloid beta (1-42) peptide-induced apoptosis in IMR-32 cells: a case of nutrigenomic. Brain Res Bull 71, 29-36.
    • (2006) Brain Res Bull , vol.71 , pp. 29-36
    • Misiti, F.1    Sampaolese, B.2    Mezzogori, D.3    Orsini, F.4    Pezzotti, M.5    Giardina, B.6    Clementi, M.E.7
  • 43
    • 58149498818 scopus 로고    scopus 로고
    • Garlic extract exhibits antiamyloidogenic activity on amyloid-beta fibrillogenesis: Relevance to Alzheimer's disease
    • Gupta VB, Indi SS, Rao KSJ (2009) Garlic extract exhibits antiamyloidogenic activity on amyloid-beta fibrillogenesis: relevance to Alzheimer's disease. Phytother Res 23, 111-115.
    • (2009) Phytother Res , vol.23 , pp. 111-115
    • Gupta, V.B.1    Indi, S.S.2    Rao, K.S.J.3
  • 44
    • 49149083439 scopus 로고    scopus 로고
    • Neuroprotection by Spirulina platensis protean extract and phycocyanin against iron-induced toxicity in SH-SY5Y neuroblastoma cells
    • Bermejo-Bescos P, Pinero-Estrada E, del Fresno AMV (2008) Neuroprotection by Spirulina platensis protean extract and phycocyanin against iron-induced toxicity in SH-SY5Y neuroblastoma cells. Toxicol in Vitro 22, 1496-1502.
    • (2008) Toxicol in Vitro , vol.22 , pp. 1496-1502
    • Bermejo-Bescos, P.1    Pinero-Estrada, E.2    Del Fresno, A.M.V.3
  • 45
    • 13244273760 scopus 로고    scopus 로고
    • Ginger extract inhibits beta-amyloid peptide-induced cytokine and chemokine expression in cultured THP-1 monocytes
    • Grzanna R, Phan P, Polotsky A, Lindmark L, Frondoza CG (2004) Ginger extract inhibits beta-amyloid peptide-induced cytokine and chemokine expression in cultured THP-1 monocytes. J Altern Complement Med 10, 1009-1013.
    • (2004) J Altern Complement Med , vol.10 , pp. 1009-1013
    • Grzanna, R.1    Phan, P.2    Polotsky, A.3    Lindmark, L.4    Frondoza, C.G.5
  • 46
    • 43849093857 scopus 로고    scopus 로고
    • Antiinflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs
    • Tung YT, Chua MT, Wang SY, Chang ST (2008) Antiinflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs. Bioresour Technol 99, 3908-3913.
    • (2008) Bioresour Technol , vol.99 , pp. 3908-3913
    • Tung, Y.T.1    Chua, M.T.2    Wang, S.Y.3    Chang, S.T.4
  • 48
    • 40849094046 scopus 로고    scopus 로고
    • Phenolic profile and antioxidant activity of highbush blueberry (Vaccinium corymbosum L.) during fruit maturation and ripening
    • Castrejon ADR, Elchholz I, Rohn S, Kroh LW, Huyskens-Keil S (2008) Phenolic profile and antioxidant activity of highbush blueberry (Vaccinium corymbosum L.) during fruit maturation and ripening. Food Chem 109, 564-572.
    • (2008) Food Chem , vol.109 , pp. 564-572
    • Castrejon, A.D.R.1    Elchholz, I.2    Rohn, S.3    Kroh, L.W.4    Huyskens-Keil, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.