메뉴 건너뛰기




Volumn 71, Issue 1-3, 2006, Pages 29-36

Protective effect of rhubarb derivatives on amyloid beta (1-42) peptide-induced apoptosis in IMR-32 cells: A case of nutrigenomic

Author keywords

Alzheimer; Amyloid beta (1 42) peptide; Apoptosis; Bax; Bcl 2; Rhaponticin; Rhapontigenin

Indexed keywords

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MITOCHONDRIA; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; OXYGEN CONSUMPTION; PEPTIDE FRAGMENTS; PLANT EXTRACTS; RHEUM; SENILE PLAQUES; SIGNAL TRANSDUCTION; STILBENES;

EID: 33751234808     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2006.07.012     Document Type: Article
Times cited : (35)

References (59)
  • 1
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: arbiters of cell survival
    • Adams J.M., and Cory S. The Bcl-2 protein family: arbiters of cell survival. Science 281 (1998) 1322-1326
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 2
    • 1342347866 scopus 로고    scopus 로고
    • Pro-oxidant activity of low doses of resveratrol inhibits hydrogen peroxide-induced apoptosis
    • Ahmad K.A., Clement M.V., and Pervaiz S. Pro-oxidant activity of low doses of resveratrol inhibits hydrogen peroxide-induced apoptosis. Ann. NY Acad. Sci. 1010 (2003) 365-373
    • (2003) Ann. NY Acad. Sci. , vol.1010 , pp. 365-373
    • Ahmad, K.A.1    Clement, M.V.2    Pervaiz, S.3
  • 3
    • 28244495389 scopus 로고    scopus 로고
    • Natural antioxidants and neurodegenerative diseases
    • Bastianetto S., and Quirion R. Natural antioxidants and neurodegenerative diseases. Front. Biosci. 9 (2004) 3447-3452
    • (2004) Front. Biosci. , vol.9 , pp. 3447-3452
    • Bastianetto, S.1    Quirion, R.2
  • 5
    • 0029998346 scopus 로고    scopus 로고
    • The serpin-enzyme complex receptor recognizes soluble, nontoxic amyloid-beta peptide but not aggregated, cytotoxic amyloid-beta peptide
    • Boland K., Behrens M., Choi D., Manias K., and Perlmutter D.H. The serpin-enzyme complex receptor recognizes soluble, nontoxic amyloid-beta peptide but not aggregated, cytotoxic amyloid-beta peptide. J. Biol. Chem. 271 30 (1996) 18032-18044
    • (1996) J. Biol. Chem. , vol.271 , Issue.30 , pp. 18032-18044
    • Boland, K.1    Behrens, M.2    Choi, D.3    Manias, K.4    Perlmutter, D.H.5
  • 6
    • 0031962324 scopus 로고    scopus 로고
    • Bcl-2 protects isolated plasma and mitochondrial membranes against lipid peroxidation induced by hydrogen peroxide and amyloid beta-peptide
    • Bruce-Keller A.J., Begley J.G., Fu W., Butterfield D.A., Bredesen D.E., Hutchins J.B., Hensley K., and Mattson M.P. Bcl-2 protects isolated plasma and mitochondrial membranes against lipid peroxidation induced by hydrogen peroxide and amyloid beta-peptide. J. Neurochem. 70 1 (1998) 31-39
    • (1998) J. Neurochem. , vol.70 , Issue.1 , pp. 31-39
    • Bruce-Keller, A.J.1    Begley, J.G.2    Fu, W.3    Butterfield, D.A.4    Bredesen, D.E.5    Hutchins, J.B.6    Hensley, K.7    Mattson, M.P.8
  • 7
    • 0035045290 scopus 로고    scopus 로고
    • Intracellular Bax translocation after transient cerebral ischemia: implications for a role of the mitochondrial apoptotic signalling pathway in ischemic neuronal death
    • Cao G., Minami M., Pei W., Yan C., Chen D., O'Horo C., Graham S.H., and Chen J. Intracellular Bax translocation after transient cerebral ischemia: implications for a role of the mitochondrial apoptotic signalling pathway in ischemic neuronal death. J. Cereb. Blood Flow Metab. 21 4 (2001) 321-333
    • (2001) J. Cereb. Blood Flow Metab. , vol.21 , Issue.4 , pp. 321-333
    • Cao, G.1    Minami, M.2    Pei, W.3    Yan, C.4    Chen, D.5    O'Horo, C.6    Graham, S.H.7    Chen, J.8
  • 8
    • 33644499467 scopus 로고    scopus 로고
    • A beta(25-35) peptide induces cell death in Pc 12 cells via mitochondrial damage and cytochrome c release
    • Carelli C., Pezzotti M., Mezzogori D., Clementi M.E., Misiti F., Giardina B., and Orsini F. A beta(25-35) peptide induces cell death in Pc 12 cells via mitochondrial damage and cytochrome c release. J. Biol. Sci. 6 1 (2006) 140-145
    • (2006) J. Biol. Sci. , vol.6 , Issue.1 , pp. 140-145
    • Carelli, C.1    Pezzotti, M.2    Mezzogori, D.3    Clementi, M.E.4    Misiti, F.5    Giardina, B.6    Orsini, F.7
  • 9
    • 0032971740 scopus 로고    scopus 로고
    • Anti-allergic action of resveratrol and related hydroxystilbenes
    • Cheong H., Ryu S.Y., and Kim K.M. Anti-allergic action of resveratrol and related hydroxystilbenes. Planta Med. 65 3 (1999) 266-268
    • (1999) Planta Med. , vol.65 , Issue.3 , pp. 266-268
    • Cheong, H.1    Ryu, S.Y.2    Kim, K.M.3
  • 10
    • 32644475566 scopus 로고    scopus 로고
    • Alzheimer's amyloid beta-peptide (1-42) induces cell death in human neroblastoma via bax/bcl-2 ratio increase: an intriguing role for methionine 35
    • Clementi M.E., Pezzotti M., Orsini F., Sampaolese B., Mezzogori D., Grassi C., Giardina B., and Misiti F. Alzheimer's amyloid beta-peptide (1-42) induces cell death in human neroblastoma via bax/bcl-2 ratio increase: an intriguing role for methionine 35. Biochem. Biophys. Res. Commun. 342 (2006) 206-213
    • (2006) Biochem. Biophys. Res. Commun. , vol.342 , pp. 206-213
    • Clementi, M.E.1    Pezzotti, M.2    Orsini, F.3    Sampaolese, B.4    Mezzogori, D.5    Grassi, C.6    Giardina, B.7    Misiti, F.8
  • 11
    • 2342468058 scopus 로고    scopus 로고
    • Effect of resveratrol and catechin on PC12 tyrosine kinase activities and their synergistic protection from beta-amyloid toxicity
    • Conte A., Pellegrini S., and Tagliazucchi D. Effect of resveratrol and catechin on PC12 tyrosine kinase activities and their synergistic protection from beta-amyloid toxicity. Drugs Exp. Clin. Res. 29 5-6 (2003) 243-255
    • (2003) Drugs Exp. Clin. Res. , vol.29 , Issue.5-6 , pp. 243-255
    • Conte, A.1    Pellegrini, S.2    Tagliazucchi, D.3
  • 12
    • 0025899234 scopus 로고
    • Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture
    • Cory A.H., Owen T.C., Barltrop J.A., and Cory J.G. Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture. Cancer Commun. 3 7 (1991) 207-212
    • (1991) Cancer Commun. , vol.3 , Issue.7 , pp. 207-212
    • Cory, A.H.1    Owen, T.C.2    Barltrop, J.A.3    Cory, J.G.4
  • 14
    • 0037132547 scopus 로고    scopus 로고
    • Antioxidants induce different phenotypes by a distinct modulation of signal transduction
    • Della Ragione F., Cucciola V., Criniti V., Indaco S., Borriello A., and Zappia V. Antioxidants induce different phenotypes by a distinct modulation of signal transduction. FEBS Lett. 532 3 (2002) 289-294
    • (2002) FEBS Lett. , vol.532 , Issue.3 , pp. 289-294
    • Della Ragione, F.1    Cucciola, V.2    Criniti, V.3    Indaco, S.4    Borriello, A.5    Zappia, V.6
  • 15
    • 30744441162 scopus 로고    scopus 로고
    • Resveratrol ameliorates myocardial damage by inducing vascular endothelial growth factor-angiogenesis and tyrosine kinase receptor Flk-1
    • Fukuda S., Kaga S., Zhan L., Bagchi D., Das D.K., Bertelli A., and Maulik N. Resveratrol ameliorates myocardial damage by inducing vascular endothelial growth factor-angiogenesis and tyrosine kinase receptor Flk-1. Cell Biochem. Biophys. 44 1 (2006) 43-49
    • (2006) Cell Biochem. Biophys. , vol.44 , Issue.1 , pp. 43-49
    • Fukuda, S.1    Kaga, S.2    Zhan, L.3    Bagchi, D.4    Das, D.K.5    Bertelli, A.6    Maulik, N.7
  • 16
    • 0042838303 scopus 로고    scopus 로고
    • Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss
    • Gong Y., Chang L., Viola K.L., Lacor P.N., Lambert M.P., Finch C.E., Krafft G.A., and Klein W.L. Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss. Proc. Natl. Acad. Sci. U.S.A. 100 18 (2003) 10417-10422
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , Issue.18 , pp. 10417-10422
    • Gong, Y.1    Chang, L.2    Viola, K.L.3    Lacor, P.N.4    Lambert, M.P.5    Finch, C.E.6    Krafft, G.A.7    Klein, W.L.8
  • 17
    • 1942472491 scopus 로고    scopus 로고
    • Neuroprotective effects of resveratrol against beta-amyloid-induced neurotoxicity in rat hippocampal neurons: involvement of protein kinase C
    • Han Y.S., Zheng W.H., Bastianetto S., Chabot J.G., and Quirion R. Neuroprotective effects of resveratrol against beta-amyloid-induced neurotoxicity in rat hippocampal neurons: involvement of protein kinase C. Br. J. Pharm. 141 6 (2004) 997-1005
    • (2004) Br. J. Pharm. , vol.141 , Issue.6 , pp. 997-1005
    • Han, Y.S.1    Zheng, W.H.2    Bastianetto, S.3    Chabot, J.G.4    Quirion, R.5
  • 18
    • 22044442164 scopus 로고    scopus 로고
    • Amyloid-beta fibril formation is not necessarily required for microglial activation by the peptides
    • Hashioka S., Monji A., Ueda T., Kanba S., and Nakanishi H. Amyloid-beta fibril formation is not necessarily required for microglial activation by the peptides. Neurochem. Int. 47 5 (2005) 369-376
    • (2005) Neurochem. Int. , vol.47 , Issue.5 , pp. 369-376
    • Hashioka, S.1    Monji, A.2    Ueda, T.3    Kanba, S.4    Nakanishi, H.5
  • 19
    • 0037446328 scopus 로고    scopus 로고
    • Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death
    • Jang J.H., and Surh Y.J. Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death. Free Radic. Biol. Med. 34 8 (2003) 1100-1110
    • (2003) Free Radic. Biol. Med. , vol.34 , Issue.8 , pp. 1100-1110
    • Jang, J.H.1    Surh, Y.J.2
  • 20
    • 19444377638 scopus 로고    scopus 로고
    • Beta-amyloid-induced apoptosis is associated with cyclooxygenase-2 up-regulation via the mitogen-activated protein kinase-NF-kappa B signalling pathway
    • Jang J.H., and Surh Y.J. Beta-amyloid-induced apoptosis is associated with cyclooxygenase-2 up-regulation via the mitogen-activated protein kinase-NF-kappa B signalling pathway. Free Radic. Biol. Med. 38 (2005) 1604-1613
    • (2005) Free Radic. Biol. Med. , vol.38 , pp. 1604-1613
    • Jang, J.H.1    Surh, Y.J.2
  • 21
    • 0034932102 scopus 로고    scopus 로고
    • Inhibitors from rhubarb on lipopolysaccharide-induced nitric oxide production in macrophages: structural requirements of stilbenes for the activity
    • Kageura T., Matsuda H., Morikawa T., Togukida I., Harima S., Oda M., and Yoscikawa M. Inhibitors from rhubarb on lipopolysaccharide-induced nitric oxide production in macrophages: structural requirements of stilbenes for the activity. Bioorg. Med. Chem. 9 7 (2001) 1887-1893
    • (2001) Bioorg. Med. Chem. , vol.9 , Issue.7 , pp. 1887-1893
    • Kageura, T.1    Matsuda, H.2    Morikawa, T.3    Togukida, I.4    Harima, S.5    Oda, M.6    Yoscikawa, M.7
  • 23
    • 0037013315 scopus 로고    scopus 로고
    • Oxyresveratrol and hydroxystilbene compounds. Inhibitory effect on tyrosinase and mechanism of action
    • Kim Y.M., Yun J., Lee C.K., Lee H., Min K.R., and Kim Y. Oxyresveratrol and hydroxystilbene compounds. Inhibitory effect on tyrosinase and mechanism of action. J. Biol. Chem. 277 18 (2002) 16340-16344
    • (2002) J. Biol. Chem. , vol.277 , Issue.18 , pp. 16340-16344
    • Kim, Y.M.1    Yun, J.2    Lee, C.K.3    Lee, H.4    Min, K.R.5    Kim, Y.6
  • 24
    • 0035993237 scopus 로고    scopus 로고
    • A beta toxicity in Alzheimer's disease: globular oligomers (ADDLs) as new vaccine and drug targets
    • Klein W.L. A beta toxicity in Alzheimer's disease: globular oligomers (ADDLs) as new vaccine and drug targets. Neurochem. Int. 41 5 (2002) 345-352
    • (2002) Neurochem. Int. , vol.41 , Issue.5 , pp. 345-352
    • Klein, W.L.1
  • 25
    • 0035297712 scopus 로고    scopus 로고
    • Targeting small A beta oligomers: the solution to an Alzheimer's disease conundrum?
    • Klein W.L., Krafft G.A., and Finch C.E. Targeting small A beta oligomers: the solution to an Alzheimer's disease conundrum?. Trends Neurosci. 24 4 (2001) 219-224
    • (2001) Trends Neurosci. , vol.24 , Issue.4 , pp. 219-224
    • Klein, W.L.1    Krafft, G.A.2    Finch, C.E.3
  • 26
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis
    • Kluck R.M., Bossy-Wetzel E., Green D.R., and Newmeyer D.D. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275 5303 (1997) 1132-1136
    • (1997) Science , vol.275 , Issue.5303 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 27
    • 0034877148 scopus 로고    scopus 로고
    • Bcl-x(S) can form homodimers and heterodimers and its apoptotic activity requires localization of Bcl-x(S) to the mitochondria and its BH3 and loop domains
    • Lindenboim L., Borner C., and Stein R. Bcl-x(S) can form homodimers and heterodimers and its apoptotic activity requires localization of Bcl-x(S) to the mitochondria and its BH3 and loop domains. Cell Death Differ. 8 9 (2001) 933-942
    • (2001) Cell Death Differ. , vol.8 , Issue.9 , pp. 933-942
    • Lindenboim, L.1    Borner, C.2    Stein, R.3
  • 29
    • 0028172886 scopus 로고
    • β-Amyloid neurotoxicity requires fibril formation and its inhibited by Congo red
    • Lorenzo A., and Yanker B.A. β-Amyloid neurotoxicity requires fibril formation and its inhibited by Congo red. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 12243-12247
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 12243-12247
    • Lorenzo, A.1    Yanker, B.A.2
  • 30
    • 0034696073 scopus 로고    scopus 로고
    • Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages
    • Matsuda H., Kageura T., Morikawa T., Toguchida I., Harima S., and Yoshikawa M. Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages. Bioorg. Med. Chem. Lett. 10 4 (2000) 323-327
    • (2000) Bioorg. Med. Chem. Lett. , vol.10 , Issue.4 , pp. 323-327
    • Matsuda, H.1    Kageura, T.2    Morikawa, T.3    Toguchida, I.4    Harima, S.5    Yoshikawa, M.6
  • 31
    • 4444335573 scopus 로고    scopus 로고
    • Anti-allergic activity of stilbenes from Korean rhubarb (Rheum undulatum L.): structure requirements for inhibition of antigen-induced degranulation and their effects on the release of TNF-alpha and IL-4 in RBL-2H3 cells
    • Matsuda H., Tewtrakul S., Morikawa T., and Yoshikawa M. Anti-allergic activity of stilbenes from Korean rhubarb (Rheum undulatum L.): structure requirements for inhibition of antigen-induced degranulation and their effects on the release of TNF-alpha and IL-4 in RBL-2H3 cells. Bioorg. Med. Chem. 12 18 (2004) 4871-4876
    • (2004) Bioorg. Med. Chem. , vol.12 , Issue.18 , pp. 4871-4876
    • Matsuda, H.1    Tewtrakul, S.2    Morikawa, T.3    Yoshikawa, M.4
  • 32
    • 0033515808 scopus 로고    scopus 로고
    • Resveratrol-induced activation of the mitogen-activated protein kinases, ERK1 and ERK2, in human neuroblastoma SH-SY5Y cells
    • Miloso M., Bertelli A.A., Nicolini G., and Tredici G. Resveratrol-induced activation of the mitogen-activated protein kinases, ERK1 and ERK2, in human neuroblastoma SH-SY5Y cells. Neurosci. Lett. 264 1-3 (1999) 141-144
    • (1999) Neurosci. Lett. , vol.264 , Issue.1-3 , pp. 141-144
    • Miloso, M.1    Bertelli, A.A.2    Nicolini, G.3    Tredici, G.4
  • 33
    • 2942631225 scopus 로고    scopus 로고
    • Methionine 35 oxidation reduces toxic and pro-apoptotic effects of the amyloid beta protein fragment (31-35) on isolated brain mitochondria
    • Misiti F., Martorana G.E., Nocca G., Di Stasio E., Giardina B., and Clementi M.E. Methionine 35 oxidation reduces toxic and pro-apoptotic effects of the amyloid beta protein fragment (31-35) on isolated brain mitochondria. Neuroscience 126 (2004) 297-303
    • (2004) Neuroscience , vol.126 , pp. 297-303
    • Misiti, F.1    Martorana, G.E.2    Nocca, G.3    Di Stasio, E.4    Giardina, B.5    Clementi, M.E.6
  • 34
    • 0034059440 scopus 로고    scopus 로고
    • Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells
    • Murphy K.M., Ranganathan V., Farnsworth M.L., Kavallaris M., and Lock R.B. Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells. Cell Death Differ. 7 1 (2000) 102-111
    • (2000) Cell Death Differ. , vol.7 , Issue.1 , pp. 102-111
    • Murphy, K.M.1    Ranganathan, V.2    Farnsworth, M.L.3    Kavallaris, M.4    Lock, R.B.5
  • 35
    • 0037375768 scopus 로고    scopus 로고
    • Effect of trans-resveratrol on signal transduction pathways involved in paclitaxel-induced apoptosis in human neuroblastoma SH-SY5Y cells
    • Nicolini G., Rigolio R., Scuteri A., Mieloso M., Saccomanno D., Cavalletti G., and Tredici G. Effect of trans-resveratrol on signal transduction pathways involved in paclitaxel-induced apoptosis in human neuroblastoma SH-SY5Y cells. Neurochem. Int. 42 5 (2003) 419-429
    • (2003) Neurochem. Int. , vol.42 , Issue.5 , pp. 419-429
    • Nicolini, G.1    Rigolio, R.2    Scuteri, A.3    Mieloso, M.4    Saccomanno, D.5    Cavalletti, G.6    Tredici, G.7
  • 36
    • 31744447521 scopus 로고    scopus 로고
    • Anti-Parkinsonian agents have anti-amyloidogenic activity for Alzheimer's beta-amyloid fibrils in vitro
    • Ono K., Hasegawa K., Naiki H., and Yamada M. Anti-Parkinsonian agents have anti-amyloidogenic activity for Alzheimer's beta-amyloid fibrils in vitro. Neurochem. Int. 48 4 (2006) 275-285
    • (2006) Neurochem. Int. , vol.48 , Issue.4 , pp. 275-285
    • Ono, K.1    Hasegawa, K.2    Naiki, H.3    Yamada, M.4
  • 37
    • 0141642253 scopus 로고    scopus 로고
    • Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease
    • Ono K., Yoshiike Y., Takashima A., Hasegawa K., Naiki H., and Yamada M. Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease. J. Neurochem. 87 1 (2003) 172-181
    • (2003) J. Neurochem. , vol.87 , Issue.1 , pp. 172-181
    • Ono, K.1    Yoshiike, Y.2    Takashima, A.3    Hasegawa, K.4    Naiki, H.5    Yamada, M.6
  • 38
    • 33644854620 scopus 로고    scopus 로고
    • Comparative studies of the antioxidant effects of cis- and trans-resveratrol
    • Orallo F. Comparative studies of the antioxidant effects of cis- and trans-resveratrol. Curr. Med. Chem. 13 1 (2006) 87-98
    • (2006) Curr. Med. Chem. , vol.13 , Issue.1 , pp. 87-98
    • Orallo, F.1
  • 39
    • 0034790052 scopus 로고    scopus 로고
    • Bcl-2 overexpression attenuates resveratrol-induced apoptosis in U937 cells by inhibition of caspase-3 activity
    • Park J.W., Choi Y.J., and Suh S.I. Bcl-2 overexpression attenuates resveratrol-induced apoptosis in U937 cells by inhibition of caspase-3 activity. Carcinogenesis 22 10 (2001) 1633-1639
    • (2001) Carcinogenesis , vol.22 , Issue.10 , pp. 1633-1639
    • Park, J.W.1    Choi, Y.J.2    Suh, S.I.3
  • 40
    • 0036690401 scopus 로고    scopus 로고
    • Antithrombotic and antiallergic activities of rhaponticin from Rhei rhizoma are activated by human intestinal bacteria
    • Park E.K., Choo M.K., Yoon H.K., and Kim D.H. Antithrombotic and antiallergic activities of rhaponticin from Rhei rhizoma are activated by human intestinal bacteria. Arch. Pharm. Res. 25 4 (2002) 528-533
    • (2002) Arch. Pharm. Res. , vol.25 , Issue.4 , pp. 528-533
    • Park, E.K.1    Choo, M.K.2    Yoon, H.K.3    Kim, D.H.4
  • 41
    • 0032502866 scopus 로고    scopus 로고
    • Disruption of the outer mitochondrial membrane as a result of large amplitude swelling: the impact of irreversible permeability transition
    • Petit P.X., Goubern M., Diolez P., Susin S.A., Zamzami N., and Kroemer G. Disruption of the outer mitochondrial membrane as a result of large amplitude swelling: the impact of irreversible permeability transition. FEBS Lett. 426 1 (1998) 111-116
    • (1998) FEBS Lett. , vol.426 , Issue.1 , pp. 111-116
    • Petit, P.X.1    Goubern, M.2    Diolez, P.3    Susin, S.A.4    Zamzami, N.5    Kroemer, G.6
  • 42
    • 0025992417 scopus 로고
    • In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity
    • Pike A.J., Walencewicz A.J., Gable C.G., and Cotman C.W. In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity. Brain Res. 563 (1991) 311-314
    • (1991) Brain Res. , vol.563 , pp. 311-314
    • Pike, A.J.1    Walencewicz, A.J.2    Gable, C.G.3    Cotman, C.W.4
  • 43
    • 0027447286 scopus 로고
    • Neurodegeneration induced by β-amyloid peptides in vitro: the role of peptide assembly state
    • Pike C.J., Burdick D., Welencewicz A.J., Glabe C.G., and Cotman C.W. Neurodegeneration induced by β-amyloid peptides in vitro: the role of peptide assembly state. J. Neurosci. 13 (1993) 1676-1678
    • (1993) J. Neurosci. , vol.13 , pp. 1676-1678
    • Pike, C.J.1    Burdick, D.2    Welencewicz, A.J.3    Glabe, C.G.4    Cotman, C.W.5
  • 44
    • 0030255449 scopus 로고    scopus 로고
    • Mechanisms of Bcl-2 family protein function and dysfunction in health and disease
    • Reed J.C. Mechanisms of Bcl-2 family protein function and dysfunction in health and disease. Behring. Inst. Mitt. 97 (1996) 72-100
    • (1996) Behring. Inst. Mitt. , Issue.97 , pp. 72-100
    • Reed, J.C.1
  • 46
    • 0036130889 scopus 로고    scopus 로고
    • Apotosis and cancer: when BAX is TRAILing away
    • Roth W., and Reed J.C. Apotosis and cancer: when BAX is TRAILing away. Nat. Med. 8 (2002) 216-218
    • (2002) Nat. Med. , vol.8 , pp. 216-218
    • Roth, W.1    Reed, J.C.2
  • 47
    • 27444439740 scopus 로고    scopus 로고
    • Preparative enzymatic synthesis and HPLC analysis of rhapontigenin: applications to metabolism, pharmacokinetics and anti-cancer studies
    • Roupe K.A., Helms G.L., Halls S.C., Yanez J.A., and Davies N.M. Preparative enzymatic synthesis and HPLC analysis of rhapontigenin: applications to metabolism, pharmacokinetics and anti-cancer studies. J. Pharm. Sci. 8 3 (2005) 374-386
    • (2005) J. Pharm. Sci. , vol.8 , Issue.3 , pp. 374-386
    • Roupe, K.A.1    Helms, G.L.2    Halls, S.C.3    Yanez, J.A.4    Davies, N.M.5
  • 48
    • 0028123071 scopus 로고
    • Alzheimer's disease: a central role for amyloid
    • Selkoe D.J. Alzheimer's disease: a central role for amyloid. J. Neurophathol. Exp. Neurol. 53 (1994) 438-447
    • (1994) J. Neurophathol. Exp. Neurol. , vol.53 , pp. 438-447
    • Selkoe, D.J.1
  • 49
    • 0032040745 scopus 로고    scopus 로고
    • Inhibitory effects of hydroxystilbenes on cyclooxygenase from sheep seminal vesicles
    • Shin N.H., Ryu S.Y., Lee H., Min K.R., and Kim Y. Inhibitory effects of hydroxystilbenes on cyclooxygenase from sheep seminal vesicles. Planta Med. 64 3 (1998) 283-284
    • (1998) Planta Med. , vol.64 , Issue.3 , pp. 283-284
    • Shin, N.H.1    Ryu, S.Y.2    Lee, H.3    Min, K.R.4    Kim, Y.5
  • 50
    • 3042698849 scopus 로고    scopus 로고
    • Tauroursodeoxycholic acid prevents amyloid-beta peptide-induced neuronal death via a phosphatidylinositol 3-kinase-dependent signaling pathway
    • Solà S., Castro R.E., Laires P.A., Steer C.J., and Rodrigues C.M. Tauroursodeoxycholic acid prevents amyloid-beta peptide-induced neuronal death via a phosphatidylinositol 3-kinase-dependent signaling pathway. Mol. Med. 9 9-12 (2003) 226-234
    • (2003) Mol. Med. , vol.9 , Issue.9-12 , pp. 226-234
    • Solà, S.1    Castro, R.E.2    Laires, P.A.3    Steer, C.J.4    Rodrigues, C.M.5
  • 51
    • 32844461956 scopus 로고    scopus 로고
    • Resveratrol downregulates the constitutional activation of nuclear factor-kappaB in multiple myeloma cells, leading to suppression of proliferation and invasion, arrest of cell cycle, and induction of apoptosis
    • Sun C., Hu Y., Liu X., Wu T., Wang Y., He W., and Wei W. Resveratrol downregulates the constitutional activation of nuclear factor-kappaB in multiple myeloma cells, leading to suppression of proliferation and invasion, arrest of cell cycle, and induction of apoptosis. Cancer Genet. Cytogenet. 165 1 (2006) 9-19
    • (2006) Cancer Genet. Cytogenet. , vol.165 , Issue.1 , pp. 9-19
    • Sun, C.1    Hu, Y.2    Liu, X.3    Wu, T.4    Wang, Y.5    He, W.6    Wei, W.7
  • 52
    • 4444226105 scopus 로고    scopus 로고
    • Neurological mechanisms of green tea polyphenols in Alzheimer's and Parkinson's diseases
    • Weireb O., Mandel S., Anit T., and Youdim M.B. Neurological mechanisms of green tea polyphenols in Alzheimer's and Parkinson's diseases. J. Nutr. Biochem. 15 9 (2004) 506-516
    • (2004) J. Nutr. Biochem. , vol.15 , Issue.9 , pp. 506-516
    • Weireb, O.1    Mandel, S.2    Anit, T.3    Youdim, M.B.4
  • 54
    • 0029996091 scopus 로고    scopus 로고
    • Physical, morphological and functional differences between pH 5.8 and 7.4 aggregates of the Alzheimer's amyloid peptide, A beta
    • Wood S.J., Maleef B., Hart T., and Wetzel R. Physical, morphological and functional differences between pH 5.8 and 7.4 aggregates of the Alzheimer's amyloid peptide, A beta. J. Mol. Biol. 256 5 (1996) 870-877
    • (1996) J. Mol. Biol. , vol.256 , Issue.5 , pp. 870-877
    • Wood, S.J.1    Maleef, B.2    Hart, T.3    Wetzel, R.4
  • 55
    • 0033564780 scopus 로고    scopus 로고
    • Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein over-expression in the rat hippocampus
    • Xu D., Bureau Y., McIntyre D.C., Nicholson D.W., Liston P., Zhu Y., Fong W.G., Crocker S.J., Korneluk R.G., and Robertson G.S. Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein over-expression in the rat hippocampus. J. Neurosci. 19 12 (1999) 5026-5033
    • (1999) J. Neurosci. , vol.19 , Issue.12 , pp. 5026-5033
    • Xu, D.1    Bureau, Y.2    McIntyre, D.C.3    Nicholson, D.W.4    Liston, P.5    Zhu, Y.6    Fong, W.G.7    Crocker, S.J.8    Korneluk, R.G.9    Robertson, G.S.10
  • 56
    • 0024990330 scopus 로고
    • Neurotrophic and neurotoxic effects of the amyloid beta protein: reversal by tachykinin neuropeptides
    • Yankner B., Duffy L.K., and Kirschner D.A. Neurotrophic and neurotoxic effects of the amyloid beta protein: reversal by tachykinin neuropeptides. Science 25 (1990) 279-282
    • (1990) Science , vol.25 , pp. 279-282
    • Yankner, B.1    Duffy, L.K.2    Kirschner, D.A.3
  • 57
    • 26844559984 scopus 로고    scopus 로고
    • Resveratrol modulates gene expression associated with apoptosis, proliferation and cell cycle in cells with mutated human c-Ha-Ras, but does not alter c-Ha-Ras mRNA or protein expression
    • Young L.F., Hantz H.L., and Martin K.R. Resveratrol modulates gene expression associated with apoptosis, proliferation and cell cycle in cells with mutated human c-Ha-Ras, but does not alter c-Ha-Ras mRNA or protein expression. J. Nutr. Biochem. 16 11 (2005) 663-674
    • (2005) J. Nutr. Biochem. , vol.16 , Issue.11 , pp. 663-674
    • Young, L.F.1    Hantz, H.L.2    Martin, K.R.3
  • 58
    • 0031436251 scopus 로고    scopus 로고
    • Heterodimerization-independent functions of cell death regulatory proteins Bax and Bcl-2 in yeast and mammalian cells
    • Zha H., and Reed J.C. Heterodimerization-independent functions of cell death regulatory proteins Bax and Bcl-2 in yeast and mammalian cells. J. Biol. Chem. 272 50 (1997) 31482-31488
    • (1997) J. Biol. Chem. , vol.272 , Issue.50 , pp. 31482-31488
    • Zha, H.1    Reed, J.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.