Computational delineation of the catalytic step of a high-fidelity DNA polymerase

Protein Science

Volumn 19, Issue 4, 2010, Pages 815-825

  Venkatramani, Ravindra ^a   Radhakrishnan, Ravi ^b,c  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Collective modes; DNA polymerase; DNA replication; Quantum mechanics molecular mechanics; Umbrella sampling

Indexed keywords

ASPARTIC ACID; DNA POLYMERASE; PYROPHOSPHATE;

ARTICLE; BACILLUS; CATALYSIS; CONTROLLED STUDY; DNA BINDING; DNA REPLICATION; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; QUANTUM MECHANICS;

BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; DNA-DIRECTED DNA POLYMERASE; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION; PROTONS; THERMODYNAMICS;

EID: 77950258668     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.361     Document Type: Article

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