Presence of 18-Å long hydrogen bond track in the active site of Escherichia coli DNA polymerase I (klenow fragment): Its requirement in the stabilization of enzyme-template-primer complex

Journal of Biological Chemistry

Volumn 278, Issue 13, 2003, Pages 11289-11302

  Singh, Kamalendra ^b   Modak, Mukund J ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CRYSTAL STRUCTURE; DNA; ENZYMES; ESCHERICHIA COLI; HYDROGEN BONDS;

HELICAL AXIS;

BIOCHEMISTRY;

AMINO ACID; ARGININE; ASPARAGINE; DNA DIRECTED DNA POLYMERASE BETA; GLYCINE; HISTIDINE; HYDROGEN; PRIMER DNA; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BASE PAIRING; BINDING AFFINITY; CATALYSIS; CATALYST; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME KINETICS; ESCHERICHIA COLI; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; ISOLATION AND PURIFICATION; KINETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA; PROKARYOTA; THERMUS; THERMUS AQUATICUS;

AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; DNA POLYMERASE I; DNA PRIMERS; ESCHERICHIA COLI; HYDROGEN BONDING; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0012768537     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M211496200     Document Type: Article

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