메뉴 건너뛰기




Volumn 235, Issue 3, 2010, Pages 356-364

Stimulation of Sigma-1 receptor by dehydroepiandrosterone ameliorates hypertension-induced kidney hypertrophy in ovariectomized rats

Author keywords

Dehydroepiandrosterone; Endothelial nitric oxide synthase; Kidney hypertrophy; Ovariectomy; Protein kinase B; Sigma 1 receptor

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; PRASTERONE; PROTEIN KINASE B; SERINE; SIGMA 1 OPIATE RECEPTOR; THREONINE;

EID: 77950190307     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1258/ebm.2009.009177     Document Type: Article
Times cited : (27)

References (65)
  • 1
    • 0028911813 scopus 로고
    • The impact of gender on the progression of chronic renal disease
    • Silbiger S, Neugarten J. The impact of gender on the progression of chronic renal disease. Am J Kidney Dis 1995;25:515-533
    • (1995) Am J Kidney Dis , vol.25 , pp. 515-533
    • Silbiger, S.1    Neugarten, J.2
  • 2
    • 0037288810 scopus 로고    scopus 로고
    • The role of gender in the progression of renal disease
    • Silbiger S, Neugarten J. The role of gender in the progression of renal disease. Adv Ren Replace Ther 2003;10:3-14
    • (2003) Adv Ren Replace Ther , vol.10 , pp. 3-14
    • Silbiger, S.1    Neugarten, J.2
  • 3
    • 0028584185 scopus 로고
    • The impact of gender on renal transplantation
    • Neugarten J, Silbiger S. The impact of gender on renal transplantation. Transplantation 1994;58:1145-1152
    • (1994) Transplantation , vol.58 , pp. 1145-1152
    • Neugarten, J.1    Silbiger, S.2
  • 4
    • 0029044009 scopus 로고
    • Effects of sex hormones on mesangial cells
    • Neugarten J, Silbiger S. Effects of sex hormones on mesangial cells. Am J Kidney Dis 1995;26:147-151
    • (1995) Am J Kidney Dis , vol.26 , pp. 147-151
    • Neugarten, J.1    Silbiger, S.2
  • 6
    • 0036838296 scopus 로고    scopus 로고
    • Gender and the progression of renal disease
    • Neugarten J. Gender and the progression of renal disease. J Am Soc Nephrol 2002;13:2807-2809
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2807-2809
    • Neugarten, J.1
  • 8
    • 0037781047 scopus 로고    scopus 로고
    • Blood pressure predicts risk of developing end-stage renal disease in men and women
    • Tozawa M, Iseki K, Iseki C, Kinjo K, Ikemiya Y, Takishita S. Blood pressure predicts risk of developing end-stage renal disease in men and women. Hypertension 2003;41:1341-1345
    • (2003) Hypertension , vol.41 , pp. 1341-1345
    • Tozawa, M.1    Iseki, K.2    Iseki, C.3    Kinjo, K.4    Ikemiya, Y.5    Takishita, S.6
  • 10
    • 0032735745 scopus 로고    scopus 로고
    • Gender differences in hypertension in spontaneously hypertensive rats: Role of androgens and androgen receptor
    • Reckelhoff JF, Zhang H, Srivastava K, Granger JP. Gender differences in hypertension in spontaneously hypertensive rats: role of androgens and androgen receptor. Hypertension 1999;34:920-923
    • (1999) Hypertension , vol.34 , pp. 920-923
    • Reckelhoff, J.F.1    Zhang, H.2    Srivastava, K.3    Granger, J.P.4
  • 11
    • 0037125379 scopus 로고    scopus 로고
    • Writing Group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the women's health initiative randomized controlled trial
    • Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, Jackson RD, Beresford SA, Howard BV, Johnson KC, Kotchen JM, Ockene J; Writing Group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the women's health initiative randomized controlled trial. JAMA 2002;288:321-333
    • (2002) JAMA , vol.288 , pp. 321-333
    • Rossouw, J.E.1    Anderson, G.L.2    Prentice, R.L.3    Lacroix, A.Z.4    Kooperberg, C.5    Stefanick, M.L.6    Jackson, R.D.7    Beresford, S.A.8    Howard, B.V.9    Johnson, K.C.10    Kotchen, J.M.11    Ockene, J.12
  • 13
    • 33947377482 scopus 로고    scopus 로고
    • Might DHEA be a beneficial replacement therapy in the elderly?
    • Genazzani AD, Lanzoni C, Genazzani AR. Might DHEA be a beneficial replacement therapy in the elderly? Drugs Aging 2007;24:173-185
    • (2007) Drugs Aging , vol.24 , pp. 173-185
    • Genazzani, A.D.1    Lanzoni, C.2    Genazzani, A.R.3
  • 14
    • 0025046185 scopus 로고
    • The effects of oral dehydroepiandrosterone on endocrine-metabolic in postmenopausal women
    • Mortola JF, Yen SCC. The effects of oral dehydroepiandrosterone on endocrine-metabolic in postmenopausal women. J Clin Endocrinol Metab 1990;71:696-704
    • (1990) J Clin Endocrinol Metab , vol.71 , pp. 696-704
    • Mortola, J.F.1    Yen, S.C.C.2
  • 15
    • 0032886387 scopus 로고    scopus 로고
    • DHEA deficiency syndrome: A new term for old age?
    • Hinson JP, Raven PW. DHEA deficiency syndrome: a new term for old age? J Endocrinol 1999;163:1-5
    • (1999) J Endocrinol , vol.163 , pp. 1-5
    • Hinson, J.P.1    Raven, P.W.2
  • 16
    • 38049141503 scopus 로고    scopus 로고
    • Biochemical and functional evidence for the control of pain mechanisms by dehydroepiandrosterone endogenously synthesized in the spinal cord
    • Kibaly C, Meyer L, Patte-Mensah C, Mensah-Nyagan AG. Biochemical and functional evidence for the control of pain mechanisms by dehydroepiandrosterone endogenously synthesized in the spinal cord. FASEB J 2008;22:93-104
    • (2008) FASEB J , vol.22 , pp. 93-104
    • Kibaly, C.1    Meyer, L.2    Patte-Mensah, C.3    Mensah-Nyagan, A.G.4
  • 18
    • 26444515048 scopus 로고    scopus 로고
    • The decline of androgen levels in elderly men and its clinical and therapeutic implications
    • Kaufman JM, Vermeulen A. The decline of androgen levels in elderly men and its clinical and therapeutic implications. Endocr Rev 2005;26:833-876
    • (2005) Endocr Rev , vol.26 , pp. 833-876
    • Kaufman, J.M.1    Vermeulen, A.2
  • 20
    • 0031732983 scopus 로고    scopus 로고
    • Serum dehydroepiandrosterone (DHEA) and DHEA sulfate are negatively correlated with serum interleukin-6 (IL-6), and DHEA inhibits IL-6 secretion from mononuclear cells in man in vitro: Possible link between endocrinosenescence and immunosenescence
    • Straub RH, Konecna L, Hrach S, Rothe G, Kreutz M, Schölmerich J, Falk W, Lang B. Serum dehydroepiandrosterone (DHEA) and DHEA sulfate are negatively correlated with serum interleukin-6 (IL-6), and DHEA inhibits IL-6 secretion from mononuclear cells in man in vitro: possible link between endocrinosenescence and immunosenescence. J Clin Endocrinol Metabol 1998;83:2012-2017
    • (1998) J Clin Endocrinol Metabol , vol.83 , pp. 2012-2017
    • Straub, R.H.1    Konecna, L.2    Hrach, S.3    Rothe, G.4    Kreutz, M.5    Schölmerich, J.6    Falk, W.7    Lang, B.8
  • 22
    • 0032979234 scopus 로고    scopus 로고
    • Role of glomerular endothelial damage in progressive renal disease
    • Yamanaka N, Shimizu A. Role of glomerular endothelial damage in progressive renal disease. Kidney Blood Press Res 1999;22:13-20
    • (1999) Kidney Blood Press Res , vol.22 , pp. 13-20
    • Yamanaka, N.1    Shimizu, A.2
  • 23
    • 4344576898 scopus 로고    scopus 로고
    • Dehydroepiandrosterone, obesity and cardiovascular disease risk: A review of human studies
    • Tchernof A, Labrie F. Dehydroepiandrosterone, obesity and cardiovascular disease risk: a review of human studies. Eur J Endocrinol 2004;151:1-14
    • (2004) Eur J Endocrinol , vol.151 , pp. 1-14
    • Tchernof, A.1    Labrie, F.2
  • 24
    • 33646815343 scopus 로고    scopus 로고
    • Low serum dehydroepiandrosterone sulfate concentration is a predictor for deterioration of urinary albumin excretion in male patients with type 2 diabetes
    • Fukui M, Kitagawa Y, Kamiuchi K, Hasegawa G, Yoshikawa T, Nakamura N. Low serum dehydroepiandrosterone sulfate concentration is a predictor for deterioration of urinary albumin excretion in male patients with type 2 diabetes. Diabetes Res Clin Pract 2006;73:47-50
    • (2006) Diabetes Res Clin Pract , vol.73 , pp. 47-50
    • Fukui, M.1    Kitagawa, Y.2    Kamiuchi, K.3    Hasegawa, G.4    Yoshikawa, T.5    Nakamura, N.6
  • 25
    • 0028283503 scopus 로고
    • Molecular mechanisms of action of steroid/thyroid receptor superfamily members
    • Tsai MJ, O'Malley BW. Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu Rev Biochem 1994;63:451-486
    • (1994) Annu Rev Biochem , vol.63 , pp. 451-486
    • Tsai, M.J.1    O'Malley, B.W.2
  • 27
    • 0028824816 scopus 로고
    • Up-regulation of high-affinity dehydroepiandrosterone binding activity by dehydroepiandrosterone in activated human T lymphocytes
    • Okabe T, Haji M, Takayanagi R, Adachi M, Imasaki K, Kurimoto F, Watanabe T, Nawata H. Up-regulation of high-affinity dehydroepiandrosterone binding activity by dehydroepiandrosterone in activated human T lymphocytes. J Clin Endocrinol Metab 1995;80:2993-2996
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 2993-2996
    • Okabe, T.1    Haji, M.2    Takayanagi, R.3    Adachi, M.4    Imasaki, K.5    Kurimoto, F.6    Watanabe, T.7    Nawata, H.8
  • 29
    • 0028990088 scopus 로고
    • Dehydroepiandrosterone inhibits B16 mouse melanoma cell growth by induction of differentiation
    • Kawai S, Yahata N, Nishida S, Nagai K, Mizushima Y. Dehydroepiandrosterone inhibits B16 mouse melanoma cell growth by induction of differentiation. Anticancer Res 1995;15:427-431
    • (1995) Anticancer Res , vol.15 , pp. 427-431
    • Kawai, S.1    Yahata, N.2    Nishida, S.3    Nagai, K.4    Mizushima, Y.5
  • 32
    • 0042816523 scopus 로고    scopus 로고
    • Dehydroepiandrosterone modulates endothelial nitric oxide synthesis via direct genomic and nongenomic mechanisms
    • Simoncini T, Mannella P, Fornari L, Varone G, Caruso A, Genazzani AR. Dehydroepiandrosterone modulates endothelial nitric oxide synthesis via direct genomic and nongenomic mechanisms. Endocrinology 2003;144:3449-3455
    • (2003) Endocrinology , vol.144 , pp. 3449-3455
    • Simoncini, T.1    Mannella, P.2    Fornari, L.3    Varone, G.4    Caruso, A.5    Genazzani, A.R.6
  • 33
    • 2942586805 scopus 로고    scopus 로고
    • Dehydroepiandrosterone stimulates nitric oxide release in vascular endothelial cells: Evidence for a cell surface receptor
    • Liu D, Dillon JS. Dehydroepiandrosterone stimulates nitric oxide release in vascular endothelial cells: evidence for a cell surface receptor. Steroids 2004;69:279-289
    • (2004) Steroids , vol.69 , pp. 279-289
    • Liu, D.1    Dillon, J.S.2
  • 35
    • 4544302443 scopus 로고    scopus 로고
    • Dehydroepiandrosterone increases endothelial cell proliferation in vitro and improves endothelial function in vivo by mechanisms independent of androgen and estrogen receptors
    • Williams MR, Dawood T, Ling S, Dai A, Lew R, Myles K, Funder JW, Sudhir K, Komesaroff PA. Dehydroepiandrosterone increases endothelial cell proliferation in vitro and improves endothelial function in vivo by mechanisms independent of androgen and estrogen receptors. J Clin Endocrinol Metab 2004;89:4708-4715
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 4708-4715
    • Williams, M.R.1    Dawood, T.2    Ling, S.3    Dai, A.4    Lew, R.5    Myles, K.6    Funder, J.W.7    Sudhir, K.8    Komesaroff, P.A.9
  • 36
    • 15944363029 scopus 로고    scopus 로고
    • Dehydroepiandrosterone inhibits the proliferation of human umbilical vein endothelial cells by enhancing the expression of p53 and p21, restricting the phosphorylation of retinoblastoma protein, and is androgen- And estrogen-receptor independent
    • Zapata E, Ventura JL, De la Cruz K, Rodriguez E, Damian P, Masso F, Montano LF, Lopez-Marure R. Dehydroepiandrosterone inhibits the proliferation of human umbilical vein endothelial cells by enhancing the expression of p53 and p21, restricting the phosphorylation of retinoblastoma protein, and is androgen- and estrogen-receptor independent. FEBS J 2005;272:1343-1353
    • (2005) FEBS J , vol.272 , pp. 1343-1353
    • Zapata, E.1    Ventura, J.L.2    De La Cruz, K.3    Rodriguez, E.4    Damian, P.5    Masso, F.6    Montano, L.F.7    Lopez-Marure, R.8
  • 37
    • 34347224378 scopus 로고    scopus 로고
    • i protein-dependent activation of phosphatidylinositol 3-kinase/Akt and regulation of antiapoptotic Bcl-2 expression
    • i protein-dependent activation of phosphatidylinositol 3-kinase/Akt and regulation of antiapoptotic Bcl-2 expression. Endocrinology 2007;148:3068-3076
    • (2007) Endocrinology , vol.148 , pp. 3068-3076
    • Liu, D.1    Si, H.2    Reynolds, K.A.3    Zhen, W.4    Jia, Z.5    Dillon, J.S.6
  • 38
    • 0034882414 scopus 로고    scopus 로고
    • Neurosteroids stimulate G protein-coupled sigma receptors in mouse brain synaptic membrane
    • Ueda H, Yoshida A, Tokuyama S, Mizuno K, Maruo J, Matsuno K, Mita S. Neurosteroids stimulate G protein-coupled sigma receptors in mouse brain synaptic membrane. Neurosci Res 2001;41:33-40
    • (2001) Neurosci Res , vol.41 , pp. 33-40
    • Ueda, H.1    Yoshida, A.2    Tokuyama, S.3    Mizuno, K.4    Maruo, J.5    Matsuno, K.6    Mita, S.7
  • 39
    • 33846620383 scopus 로고    scopus 로고
    • Neuro(active)steroids actions at the neuromodulatory sigmal (sigma 1) receptor: Biochemical and physiological evidences, consequences in neuroprotection
    • Maurice T, Gregoire C, Espallergues J. Neuro(active)steroids actions at the neuromodulatory sigmal (sigma 1) receptor: biochemical and physiological evidences, consequences in neuroprotection. Pharmacol Biochem Behav 2006;84:581-597
    • (2006) Pharmacol Biochem Behav , vol.84 , pp. 581-597
    • Maurice, T.1    Gregoire, C.2    Espallergues, J.3
  • 40
    • 39149108182 scopus 로고    scopus 로고
    • Neurosteroid dehydroepiandrosterone sulphate inhibits persistent sodium currents in rat medial prefrontal cortex via activation of sigma-1 receptors
    • Cheng ZX, Lan DM, Wu PY, Zhu YH, Dong Y, Ma L, Zheng P. Neurosteroid dehydroepiandrosterone sulphate inhibits persistent sodium currents in rat medial prefrontal cortex via activation of sigma-1 receptors. Exp Neurol 2008;210:128-136
    • (2008) Exp Neurol , vol.210 , pp. 128-136
    • Cheng, Z.X.1    Lan, D.M.2    Wu, P.Y.3    Zhu, Y.H.4    Dong, Y.5    Ma, L.6    Zheng, P.7
  • 41
    • 0033529174 scopus 로고    scopus 로고
    • Intracellular sigma 1 receptor modulates phospholipase C and protein kinase C activities in brain stem
    • Morin-Surun MP, Colin T, avit-Saubie M, Baulieu EE, Monnet FP. Intracellular sigma 1 receptor modulates phospholipase C and protein kinase C activities in brain stem. Proc Natl Acad Sci USA 1999;96:8196-8199
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 8196-8199
    • Morin-Surun, M.P.1    Colin, T.2    Avit-Saubie, M.3    Baulieu, E.E.4    Monnet, F.P.5
  • 42
    • 37149002867 scopus 로고    scopus 로고
    • Ovariectomy augments pressure overload-induced hypertrophy associated with changes in Akt and nitric oxide synthase signaling pathways in female rats
    • Bhuiyan MS, Shioda N, Fukunaga K. Ovariectomy augments pressure overload-induced hypertrophy associated with changes in Akt and nitric oxide synthase signaling pathways in female rats. Am J Physiol Endocrinol Metab 2007;293:E1606-14
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • Bhuiyan, M.S.1    Shioda, N.2    Fukunaga, K.3
  • 43
    • 58149399356 scopus 로고    scopus 로고
    • Activation of endothelial nitric oxide synthase by a vanadium compound ameliorates pressure overload-induced cardiac injury in ovariectomized rats
    • Bhuiyan MS, Shioda N, Shibuya M, Iwabuchi Y, Fukunaga K. Activation of endothelial nitric oxide synthase by a vanadium compound ameliorates pressure overload-induced cardiac injury in ovariectomized rats. Hypertension 2009;53:57-63
    • (2009) Hypertension , vol.53 , pp. 57-63
    • Bhuiyan, M.S.1    Shioda, N.2    Shibuya, M.3    Iwabuchi, Y.4    Fukunaga, K.5
  • 44
    • 33646021588 scopus 로고    scopus 로고
    • Silencing of sigma-1 receptor induces cell death in human lens cells
    • Wang L, Duncan G. Silencing of sigma-1 receptor induces cell death in human lens cells. Exp Cell Res 2006;312:1439-1446
    • (2006) Exp Cell Res , vol.312 , pp. 1439-1446
    • Wang, L.1    Duncan, G.2
  • 46
    • 65549097680 scopus 로고    scopus 로고
    • Chronic b-adrenoceptor activation-induced calpain activation and impaired eNOS-Akt signaling mediates cardiac injury in ovariectomized in female rats
    • Bhuiyan MS, Shioda N, Fukunaga K. Chronic b-adrenoceptor activation-induced calpain activation and impaired eNOS-Akt signaling mediates cardiac injury in ovariectomized in female rats. Expert Opin Ther Targets 2009;13:275-286
    • (2009) Expert Opin Ther Targets , vol.13 , pp. 275-286
    • Bhuiyan, M.S.1    Shioda, N.2    Fukunaga, K.3
  • 47
    • 0026048716 scopus 로고
    • Assay of fatty acid ω-hydroxylation using high performance liquid chromatography with fluorescence labeling reagent, 3-bromomethyl-7-methoxy-1,4- benzoxazin-2-one (BrMB)
    • Yamada J, Sakuma M, Suga T. Assay of fatty acid ω-hydroxylation using high performance liquid chromatography with fluorescence labeling reagent, 3-bromomethyl-7-methoxy-1,4-benzoxazin-2-one (BrMB). Anal Biochem 1991;199:132-136
    • (1991) Anal Biochem , vol.199 , pp. 132-136
    • Yamada, J.1    Sakuma, M.2    Suga, T.3
  • 48
    • 77950191501 scopus 로고    scopus 로고
    • Hypoxia and dehydroepiandrosterone in old age: A mouse survival study
    • Dobonneuil EH, Quillard J, Baulieu EE. Hypoxia and dehydroepiandrosterone in old age: a mouse survival study. Respiratory Res 2006;7:144
    • (2006) Respiratory Res , vol.7 , pp. 144
    • Dobonneuil, E.H.1    Quillard, J.2    Baulieu, E.E.3
  • 50
    • 0029795715 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA): A fountain of youth?
    • Baulieu EE. Dehydroepiandrosterone (DHEA): a fountain of youth? J Clin Endocrinol Metab 1996;88:3147-3151
    • (1996) J Clin Endocrinol Metab , vol.88 , pp. 3147-3151
    • Baulieu, E.E.1
  • 51
    • 0029554030 scopus 로고
    • Metabolism of dehydroepiandrosterone
    • Longcope C. Metabolism of dehydroepiandrosterone. Ann NY Acad Sci 1995;774:143-148
    • (1995) Ann NY Acad Sci , vol.774 , pp. 143-148
    • Longcope, C.1
  • 52
    • 0034644608 scopus 로고    scopus 로고
    • Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3K-Akt pathway in human endothelial cells
    • Haynes MP, Sinha D, Russell KS, Collinge M, Fulton D, Morales-Ruiz M, Sessa WC, Bender JR. Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3K-Akt pathway in human endothelial cells. Circ Res 2000;87:677-682
    • (2000) Circ Res , vol.87 , pp. 677-682
    • Haynes, M.P.1    Sinha, D.2    Russell, K.S.3    Collinge, M.4    Fulton, D.5    Morales-Ruiz, M.6    Sessa, W.C.7    Bender, J.R.8
  • 54
    • 0035192750 scopus 로고    scopus 로고
    • Post-translational control of endothelial nitric oxide synthase: Why isn't calcium/calmodulin enough?
    • Fulton D, Gratton J-P, Sessa WC. Post-translational control of endothelial nitric oxide synthase: why isn't calcium/calmodulin enough? J Pharmacol Exp Ther 2001;299:818-824
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 818-824
    • Fulton, D.1    Gratton, J.-P.2    Sessa, W.C.3
  • 55
    • 0029082051 scopus 로고
    • Nitric oxide synthase inhibition in spontaneously hypertensive rats. Systemic, renal, and glomerular hemodynamics
    • Ono H, Ono Y, Frohlich ED. Nitric oxide synthase inhibition in spontaneously hypertensive rats. Systemic, renal, and glomerular hemodynamics. Hypertension 1995;26:249-255
    • (1995) Hypertension , vol.26 , pp. 249-255
    • Ono, H.1    Ono, Y.2    Frohlich, E.D.3
  • 56
    • 0031606271 scopus 로고    scopus 로고
    • Nitric oxide synthase activity and renal injury in genetic hypertension
    • Hayakawa H, Raij L. Nitric oxide synthase activity and renal injury in genetic hypertension. Hypertension 1998;31:266-270
    • (1998) Hypertension , vol.31 , pp. 266-270
    • Hayakawa, H.1    Raij, L.2
  • 57
    • 7044222546 scopus 로고    scopus 로고
    • Effects of chronic renal failure on caveolin-1, guanylate cyclase and Akt protein expression
    • Sindhu RK, Ehdaie A, Vaziri ND, Roberts CK. Effects of chronic renal failure on caveolin-1, guanylate cyclase and Akt protein expression. Biochem Biophys Acta 2004;1690:231-237
    • (2004) Biochem Biophys Acta , vol.1690 , pp. 231-237
    • Sindhu, R.K.1    Ehdaie, A.2    Vaziri, N.D.3    Roberts, C.K.4
  • 58
    • 1442343623 scopus 로고    scopus 로고
    • Androgen therapy with dehydroepiandrosterone
    • Buvat J. Androgen therapy with dehydroepiandrosterone. World J Urol 2003;21:346-355
    • (2003) World J Urol , vol.21 , pp. 346-355
    • Buvat, J.1
  • 59
    • 0346219418 scopus 로고    scopus 로고
    • Long-term low-dose dehydroepiandrosterone oral supplementation in early and late postmenopausal woman modulates endocrine parameters and synthesis of neuroactive steroids
    • Genazzani AD, Stomati M, Bernardi F, Pieri M, Rovati L, Genazzani AR. Long-term low-dose dehydroepiandrosterone oral supplementation in early and late postmenopausal woman modulates endocrine parameters and synthesis of neuroactive steroids. Fertil Steril 2003;80:1495-1501
    • (2003) Fertil Steril , vol.80 , pp. 1495-1501
    • Genazzani, A.D.1    Stomati, M.2    Bernardi, F.3    Pieri, M.4    Rovati, L.5    Genazzani, A.R.6
  • 60
    • 0029873233 scopus 로고    scopus 로고
    • Increase of lipid peroxidation in rat liver microsomes by dehydroepiandrosterone feeding
    • Swierczynski J, Bannasch P, Mayer D. Increase of lipid peroxidation in rat liver microsomes by dehydroepiandrosterone feeding. Biochim Biophys Acta 1996;1315:193-198
    • (1996) Biochim Biophys Acta , vol.1315 , pp. 193-198
    • Swierczynski, J.1    Bannasch, P.2    Mayer, D.3
  • 61
    • 0030203263 scopus 로고    scopus 로고
    • Dehydroepiandrosterone-induced lipid peroxidation in rat liver mitochondria
    • Swierczynski J, Mayer D. Dehydroepiandrosterone-induced lipid peroxidation in rat liver mitochondria. J Steroid Biochem Mol Biol 1996;58:599-603
    • (1996) J Steroid Biochem Mol Biol , vol.58 , pp. 599-603
    • Swierczynski, J.1    Mayer, D.2
  • 62
    • 0032852385 scopus 로고    scopus 로고
    • Correlation between the administered dose of DHEA and serum levels of DHEA and DHEA-S in human volunteers: Analysis of published data
    • Tummala S, Svec F. Correlation between the administered dose of DHEA and serum levels of DHEA and DHEA-S in human volunteers: analysis of published data. Clin Biochem 1999;32:355-361
    • (1999) Clin Biochem , vol.32 , pp. 355-361
    • Tummala, S.1    Svec, F.2
  • 64
    • 34447626245 scopus 로고    scopus 로고
    • Dehydroepiandrosterone inhibits the progression phase of mammary carcinogenesis by inducing cellular senescence via a p16-dependent but p53-independent mechanism
    • Shilkaitis A, Green A, Punj V, Steele V, Lubet R, Christov K. Dehydroepiandrosterone inhibits the progression phase of mammary carcinogenesis by inducing cellular senescence via a p16-dependent but p53-independent mechanism. Breast Cancer Res 2005;7:R1132-40
    • (2005) Breast Cancer Res , vol.7
    • Shilkaitis, A.1    Green, A.2    Punj, V.3    Steele, V.4    Lubet, R.5    Christov, K.6
  • 65
    • 0034603858 scopus 로고    scopus 로고
    • Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells
    • Zeng G, Nystrom FH, Ravichandran LV, Cong LN, Kirby M, Mostowski H, Quon MJ. Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells. Circulation 2000;101:1539-1545
    • (2000) Circulation , vol.101 , pp. 1539-1545
    • Zeng, G.1    Nystrom, F.H.2    Ravichandran, L.V.3    Cong, L.N.4    Kirby, M.5    Mostowski, H.6    Quon, M.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.