Dehydroepiandrosterone inhibits the proliferation of human umbilical vein endothelial by enhancing the expression of p53 and p21, restricting the phosphorylation of retinoblastoma protein, and is androgen- and estrogen-receptor independent

FEBS Journal

Volumn 272, Issue 6, 2005, Pages 1343-1353

  Zapata, Estrella ^a   Ventura, José L ^b   De La Cruz, Karina ^c   Rodriguez, Emma ^a   Damián, Pablo ^c   Massó, Felipe ^a   Montaño, Luis F ^d   López Marure, Rebeca ^a,e  

^a INSTITUTO NACIONAL DE CARDIOLOGÍA IGNACIO CHÁVEZ   (Mexico)

^b INSTITUTO DE FISIOLOGÍA CELULAR   (Mexico)

^c DEPARTAMENTO DE QUÍMICA   (Mexico)

^d UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^e INSTITUTO NACIONAL DE CANCEROLOGÍA   (Mexico)

Author keywords

Cell cycle proteins; Dehydroepiandrosterone; HUVEC; Proliferation; TNF

Indexed keywords

ANDROGEN RECEPTOR; ESTRADIOL; ESTROGEN RECEPTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLSERINE; PRASTERONE; PRASTERONE SULFATE; PROTEIN P21; PROTEIN P53; RETINOBLASTOMA PROTEIN; STEROID HORMONE; TESTOSTERONE;

ARTICLE; CELL CYCLE G1 PHASE; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; CYTOPLASM; DOSE RESPONSE; ENDOTHELIUM CELL; ENZYME DEGRADATION; HORMONE DEPENDENCE; HUMAN; HUMAN CELL; INHIBITION KINETICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; UMBILICAL VEIN;

CELL CYCLE PROTEINS; CELL DIVISION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DEHYDROEPIANDROSTERONE; DNA; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HUMANS; PHOSPHORYLATION; RECEPTORS, ANDROGEN; RECEPTORS, ESTROGEN; RETINOBLASTOMA PROTEIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; THYMIDINE; TUMOR SUPPRESSOR PROTEIN P53; UMBILICAL VEINS;

EID: 15944363029     PISSN: 1742464X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2005.04563.x     Document Type: Article

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