Small molecule antagonists of the σ-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo

Cancer Research

Volumn 64, Issue 14, 2004, Pages 4875-4886

  Spruce, Barbara A ^a   Campbell, Lorna A ^a   McTavish, Niall ^a   Cooper, Michelle A ^a   Appleyard, M Virginia L ^a   O'Neill, Mary ^a   Howie, Jacqueline ^a   Samson, Jayne ^a   Watt, Stephen ^a   Murray, Karen ^a   McLean, Doris ^a   Leslie, Nick R ^b   Safrany, Stephen T ^b   Ferguson, Michelle J ^a   Peters, John A ^a   Prescott, Alan R ^b   Box, Gary ^c   Hayes, Angela ^c   Nutley, Bernard ^c   Raynaud, Florence ^c   Downes, C Peter ^b   Lambert, Jeremy J ^a   Thompson, Alastair M ^a   Eccles, Suzanne ^c   more..

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

N ALLYLNORMETAZOCINE; PENTAZOCINE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; RIMCAZOLE; SIGMA 1 OPIATE RECEPTOR;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; BREAST CARCINOMA; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CANCER INHIBITION; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVATION; ENZYME INHIBITION; EPITHELIUM CELL; FEMALE; FIBROBLAST; IN VITRO STUDY; IN VIVO STUDY; LUNG CARCINOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE TUMOR; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CALCIUM SIGNALING; CARBAZOLES; CASPASES; CATTLE; CELL DIVISION; CELL LINE, TUMOR; ENZYME ACTIVATION; ETHYLENEDIAMINES; HALOPERIDOL; HUMANS; ISOENZYMES; LUNG NEOPLASMS; MALE; MICE; MICE, NUDE; PHOSPHOLIPASE C; PIPERAZINES; PROSTATIC NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, SIGMA; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 3142699893     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-03-3180     Document Type: Article

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