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Volumn 59, Issue 4, 2008, Pages 293-303

One-year therapy with 10 mg/day DHEA alone or in combination with HRT in postmenopausal women: Effects on hormonal milieu

Author keywords

Androgenic deficiency; DHEA replacement therapy; HRT; Neurosteroids; Postmenopausal women; Sex steroids

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; ANDROGEN; BETA ENDORPHIN; ESTRADIOL; ESTROGEN; HYDROCORTISONE; PRASTERONE; PRASTERONE SULFATE; PROGESTERONE; TESTOSTERONE; ELTANOLONE; STEROID;

EID: 44549087256     PISSN: 03785122     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.maturitas.2008.02.004     Document Type: Article
Times cited : (31)

References (38)
  • 1
    • 0021181906 scopus 로고
    • Age changes and sex differences in serum dehydroepiandrosterone sulphate concentration throughout adulthood
    • Orentreich N., Brind J.L., Rizer R.L., and Vogelman J.H. Age changes and sex differences in serum dehydroepiandrosterone sulphate concentration throughout adulthood. J Clin Endocrinol Metab 59 3 (1984) 551-555
    • (1984) J Clin Endocrinol Metab , vol.59 , Issue.3 , pp. 551-555
    • Orentreich, N.1    Brind, J.L.2    Rizer, R.L.3    Vogelman, J.H.4
  • 2
    • 3343021042 scopus 로고    scopus 로고
    • Dehydroepiandrosterone and ageing
    • Arlt W. Dehydroepiandrosterone and ageing. Best Pract Res Clin Endocrinol Metab 18 3 (2004) 363-380
    • (2004) Best Pract Res Clin Endocrinol Metab , vol.18 , Issue.3 , pp. 363-380
    • Arlt, W.1
  • 3
    • 0030739131 scopus 로고    scopus 로고
    • Marked decline in serum concentrations of adrenal C19 sex steroids precursors and conjugated androgen metabolites during aging
    • Labrie F., Belanger A., Cusan L., Gomez J.L., and Candas B. Marked decline in serum concentrations of adrenal C19 sex steroids precursors and conjugated androgen metabolites during aging. J Clin Endocrinol Metab 82 8 (1997) 2396-2402
    • (1997) J Clin Endocrinol Metab , vol.82 , Issue.8 , pp. 2396-2402
    • Labrie, F.1    Belanger, A.2    Cusan, L.3    Gomez, J.L.4    Candas, B.5
  • 4
    • 0033511922 scopus 로고    scopus 로고
    • Changes in adrenocortical function with aging and therapeutic implications
    • Harper A.J., Buster J.E., and Casson P.R. Changes in adrenocortical function with aging and therapeutic implications. Semin Reprod Endocrinol 17 4 (1999) 327-338
    • (1999) Semin Reprod Endocrinol , vol.17 , Issue.4 , pp. 327-338
    • Harper, A.J.1    Buster, J.E.2    Casson, P.R.3
  • 5
    • 0033762851 scopus 로고    scopus 로고
    • Sexual dimorphism in the influence of advanced aging on adrenal hormone levels: the Brancho Bernardo study
    • Laughlin G.A., and Barrett-Connor E. Sexual dimorphism in the influence of advanced aging on adrenal hormone levels: the Brancho Bernardo study. J Clin Endocrinol Metab 85 10 (2000) 3561-3568
    • (2000) J Clin Endocrinol Metab , vol.85 , Issue.10 , pp. 3561-3568
    • Laughlin, G.A.1    Barrett-Connor, E.2
  • 6
    • 0025079183 scopus 로고
    • Marked attenuation of ultradian and circadian rhythms of dehydroepiandrosterone in postmenopausal women: evidence for a reduced 17, 20 desmolase activity
    • Liu C.H., Laughlin G.A., Fischer U.G., and Yen S.S. Marked attenuation of ultradian and circadian rhythms of dehydroepiandrosterone in postmenopausal women: evidence for a reduced 17, 20 desmolase activity. J Clin Endocrinol Metab 71 4 (1990) 900-906
    • (1990) J Clin Endocrinol Metab , vol.71 , Issue.4 , pp. 900-906
    • Liu, C.H.1    Laughlin, G.A.2    Fischer, U.G.3    Yen, S.S.4
  • 8
    • 23044472102 scopus 로고    scopus 로고
    • Androgen levels in adult females: changes with age, menopause and oophorectomy
    • Davison S.L., Bell R., Donath S., Montalto J.G., and Davis S.R. Androgen levels in adult females: changes with age, menopause and oophorectomy. J Clin Endocrinol Metab 90 7 (2005) 3847-3853
    • (2005) J Clin Endocrinol Metab , vol.90 , Issue.7 , pp. 3847-3853
    • Davison, S.L.1    Bell, R.2    Donath, S.3    Montalto, J.G.4    Davis, S.R.5
  • 9
    • 23644431529 scopus 로고    scopus 로고
    • The stress system in the human brain in depression and neurodegeneration
    • Swaab D.F., Bao A.M., and Lucassen P.J. The stress system in the human brain in depression and neurodegeneration. Ageing Res Rev 4 2 (2005) 141-194
    • (2005) Ageing Res Rev , vol.4 , Issue.2 , pp. 141-194
    • Swaab, D.F.1    Bao, A.M.2    Lucassen, P.J.3
  • 10
    • 33947377482 scopus 로고    scopus 로고
    • Might DHEA be a beneficial replacement therapy in the elderly?
    • Genazzani A.D., Lanzoni C., and Genazzani A.R. Might DHEA be a beneficial replacement therapy in the elderly?. Drugs Aging 24 3 (2007) 173-185
    • (2007) Drugs Aging , vol.24 , Issue.3 , pp. 173-185
    • Genazzani, A.D.1    Lanzoni, C.2    Genazzani, A.R.3
  • 11
    • 0025046185 scopus 로고
    • The effects of oral dehydroepiandrosterone on endocrine-metabolic in postmenopausal women
    • Mortola J.F., and Yen S.C.C. The effects of oral dehydroepiandrosterone on endocrine-metabolic in postmenopausal women. J Clin Endocrinol Metab 71 3 (1990) 696-704
    • (1990) J Clin Endocrinol Metab , vol.71 , Issue.3 , pp. 696-704
    • Mortola, J.F.1    Yen, S.C.C.2
  • 12
    • 0028221213 scopus 로고
    • Effects of replacement dose of dehydroepiandrosterone in men and in women of advancing age
    • Morales A.J., Nolan J.J., Nelson J.C., and Yen S.C.C. Effects of replacement dose of dehydroepiandrosterone in men and in women of advancing age. J Clin Endocrinol Metab 78 6 (1994) 1360-1367
    • (1994) J Clin Endocrinol Metab , vol.78 , Issue.6 , pp. 1360-1367
    • Morales, A.J.1    Nolan, J.J.2    Nelson, J.C.3    Yen, S.C.C.4
  • 13
    • 33845477728 scopus 로고    scopus 로고
    • Long-term low-dose oral administration of dehydroepiandrosterone modulates response to adrenocorticotropic hormone in early and late postmenopausal women
    • Genazzani A.R., Pluchino N., Begliuomini S., et al. Long-term low-dose oral administration of dehydroepiandrosterone modulates response to adrenocorticotropic hormone in early and late postmenopausal women. Gynecol Endocrinol 22 11 (2006) 627-635
    • (2006) Gynecol Endocrinol , vol.22 , Issue.11 , pp. 627-635
    • Genazzani, A.R.1    Pluchino, N.2    Begliuomini, S.3
  • 14
    • 4644246248 scopus 로고    scopus 로고
    • Long term low-dose dehydroepiandrosterone replacement therapy in aging males with partial androgen deficiency
    • Genazzani A.R., Inglese S., Lombardi I., et al. Long term low-dose dehydroepiandrosterone replacement therapy in aging males with partial androgen deficiency. Aging Male 7 2 (2004) 133-143
    • (2004) Aging Male , vol.7 , Issue.2 , pp. 133-143
    • Genazzani, A.R.1    Inglese, S.2    Lombardi, I.3
  • 15
    • 33750049989 scopus 로고    scopus 로고
    • DHEA in elderly women and DHEA or testosterone in elderly men
    • Nair K.S., Rizza R.A., O'Brien P., et al. DHEA in elderly women and DHEA or testosterone in elderly men. N Engl J Med 355 16 (2006) 1647-1659
    • (2006) N Engl J Med , vol.355 , Issue.16 , pp. 1647-1659
    • Nair, K.S.1    Rizza, R.A.2    O'Brien, P.3
  • 16
    • 34347235832 scopus 로고    scopus 로고
    • Dehydroepiandrosterone, the endothelium and cardiovascular protection
    • Simoncini T., and Genazzani A.R. Dehydroepiandrosterone, the endothelium and cardiovascular protection. Endocrinology 148 7 (2007) 3065-3067
    • (2007) Endocrinology , vol.148 , Issue.7 , pp. 3065-3067
    • Simoncini, T.1    Genazzani, A.R.2
  • 17
    • 10244252830 scopus 로고    scopus 로고
    • Effects of dehydroepiandrosterone (DHEA) supplementation on hormonal, metabolic and behavioural status in patients with hypoadrenalism
    • Libe R., Barbetta L., Dall'Asta C., Salvaggio F., Gala C., and Beck-Peccoz P. Effects of dehydroepiandrosterone (DHEA) supplementation on hormonal, metabolic and behavioural status in patients with hypoadrenalism. J Endocrinol Invest 27 8 (2004) 736-741
    • (2004) J Endocrinol Invest , vol.27 , Issue.8 , pp. 736-741
    • Libe, R.1    Barbetta, L.2    Dall'Asta, C.3    Salvaggio, F.4    Gala, C.5    Beck-Peccoz, P.6
  • 18
    • 0033237710 scopus 로고    scopus 로고
    • The effect of dehydroepiandrosterone supplementation to symptomatic perimenopausal women on serum profiles, lipid parameters, and health related quality of life
    • Barnhart K.T., Freeman E., Grisso J.A., et al. The effect of dehydroepiandrosterone supplementation to symptomatic perimenopausal women on serum profiles, lipid parameters, and health related quality of life. J Clin Endocrinol Metab 84 11 (1999) 3896-3902
    • (1999) J Clin Endocrinol Metab , vol.84 , Issue.11 , pp. 3896-3902
    • Barnhart, K.T.1    Freeman, E.2    Grisso, J.A.3
  • 19
    • 1442343623 scopus 로고    scopus 로고
    • Androgen therapy with dehydroepiandrosterone
    • Buvat J. Androgen therapy with dehydroepiandrosterone. World J Urol 21 5 (2003) 346-355
    • (2003) World J Urol , vol.21 , Issue.5 , pp. 346-355
    • Buvat, J.1
  • 20
    • 0033678636 scopus 로고    scopus 로고
    • Six oral months dehydroepiandrosterone supplementation in early and late menopause
    • Stomati M., Monteleone P., Casarosa E., et al. Six oral months dehydroepiandrosterone supplementation in early and late menopause. Gynecol Endocrinol 14 5 (2000) 342-363
    • (2000) Gynecol Endocrinol , vol.14 , Issue.5 , pp. 342-363
    • Stomati, M.1    Monteleone, P.2    Casarosa, E.3
  • 21
    • 0346219418 scopus 로고    scopus 로고
    • Long term low-dose dehydroepiandrosterone oral supplementation in early and late postmenopausal women modulates endocrine parameters and synthesis of neuroactive steroids
    • Genazzani A.D., Stomati S., Bernardi F., Pieri M., Rovati L., and Genazzani A.R. Long term low-dose dehydroepiandrosterone oral supplementation in early and late postmenopausal women modulates endocrine parameters and synthesis of neuroactive steroids. Fertil Steril 80 6 (2003) 1495-1501
    • (2003) Fertil Steril , vol.80 , Issue.6 , pp. 1495-1501
    • Genazzani, A.D.1    Stomati, S.2    Bernardi, F.3    Pieri, M.4    Rovati, L.5    Genazzani, A.R.6
  • 22
    • 33947603022 scopus 로고    scopus 로고
    • DHEA therapy for women: effect on sexual function and wellbeing
    • Panjari M., and Davis S. DHEA therapy for women: effect on sexual function and wellbeing. Hum Reprod Update 13 3 (2007) 239-248
    • (2007) Hum Reprod Update , vol.13 , Issue.3 , pp. 239-248
    • Panjari, M.1    Davis, S.2
  • 23
    • 0031756135 scopus 로고    scopus 로고
    • Estrogen and estrogen-androgen replacement in postmenopausal women dissatisfied with estrogen-only therapy. Sexual behaviour and neuroendocrine responses
    • Sarrel P., Dobay B., and Wiita B. Estrogen and estrogen-androgen replacement in postmenopausal women dissatisfied with estrogen-only therapy. Sexual behaviour and neuroendocrine responses. J Reprod Med 43 10 (1998) 847-856
    • (1998) J Reprod Med , vol.43 , Issue.10 , pp. 847-856
    • Sarrel, P.1    Dobay, B.2    Wiita, B.3
  • 24
    • 0036280959 scopus 로고    scopus 로고
    • Differential effects of oral estrogen versus oral estrogen-androgen replacement therapy on body composition in postmenopausal women
    • Dobs A.S., Nguyen T., Pace C., and Roberts C.P. Differential effects of oral estrogen versus oral estrogen-androgen replacement therapy on body composition in postmenopausal women. J Clin Endocrinol Metab 87 (2002) 1509-1516
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1509-1516
    • Dobs, A.S.1    Nguyen, T.2    Pace, C.3    Roberts, C.P.4
  • 26
    • 23044472102 scopus 로고    scopus 로고
    • Androgen levels in adult females: changes with age, menopause, and oophorectomy
    • Davison S.L., Bell R., Donath S., Montalto J.G., and Davis S.R. Androgen levels in adult females: changes with age, menopause, and oophorectomy. J Clin Endocrinol Metab 90 7 (2005) 3847-3853
    • (2005) J Clin Endocrinol Metab , vol.90 , Issue.7 , pp. 3847-3853
    • Davison, S.L.1    Bell, R.2    Donath, S.3    Montalto, J.G.4    Davis, S.R.5
  • 27
    • 15144344290 scopus 로고    scopus 로고
    • Circulating levels of allopregnanolone in humans: gender, age and endocrine influences
    • Genazzani A.R., Bernardi F., Petraglia F., et al. Circulating levels of allopregnanolone in humans: gender, age and endocrine influences. J Clin Endocrinol Metab 83 6 (1998) 1-5
    • (1998) J Clin Endocrinol Metab , vol.83 , Issue.6 , pp. 1-5
    • Genazzani, A.R.1    Bernardi, F.2    Petraglia, F.3
  • 28
    • 0031573927 scopus 로고    scopus 로고
    • Neuroendocrine effects of different oestradiol-progestin regimens in postmenopausal women
    • Stomati M., Bersi C., Rubino S., et al. Neuroendocrine effects of different oestradiol-progestin regimens in postmenopausal women. Maturitas 28 2 (1997) 127-135
    • (1997) Maturitas , vol.28 , Issue.2 , pp. 127-135
    • Stomati, M.1    Bersi, C.2    Rubino, S.3
  • 29
    • 28044466662 scopus 로고    scopus 로고
    • Is dehydroepiandrosterone a hormone?
    • Labrie F., Luu-The V., Belanger A., et al. Is dehydroepiandrosterone a hormone?. J Endocrinol 187 2 (2005) 169-196
    • (2005) J Endocrinol , vol.187 , Issue.2 , pp. 169-196
    • Labrie, F.1    Luu-The, V.2    Belanger, A.3
  • 30
    • 0029130862 scopus 로고
    • Circulating hormone levels in menopausal women receiving different hormone replacement therapy regimens. A comparison
    • Castelo-Blanco C., Martinez De Osaba M.J., Fortuny A., Iglesias X., and Gonzalez-Merlo J. Circulating hormone levels in menopausal women receiving different hormone replacement therapy regimens. A comparison. J Reprod Med 40 8 (1995) 556-560
    • (1995) J Reprod Med , vol.40 , Issue.8 , pp. 556-560
    • Castelo-Blanco, C.1    Martinez De Osaba, M.J.2    Fortuny, A.3    Iglesias, X.4    Gonzalez-Merlo, J.5
  • 31
    • 0035116676 scopus 로고    scopus 로고
    • Differential effects on the androgen status of postmenopausal women treated with tibolone and continuous combined estradiol and norethindrone acetate replacement therapy
    • Dören M., Rübig A., Coelingh Bennink H.J., and Holzgreve W. Differential effects on the androgen status of postmenopausal women treated with tibolone and continuous combined estradiol and norethindrone acetate replacement therapy. Fertil Steril 75 3 (2001) 554-559
    • (2001) Fertil Steril , vol.75 , Issue.3 , pp. 554-559
    • Dören, M.1    Rübig, A.2    Coelingh Bennink, H.J.3    Holzgreve, W.4
  • 33
    • 0034895297 scopus 로고    scopus 로고
    • DHEA and its transformation into androgens and estrogens in peripheral target tissues: intracrinology
    • Labrie F., Luu-The V., Labrie C., and Simard J. DHEA and its transformation into androgens and estrogens in peripheral target tissues: intracrinology. Front Neuroendocrinol 22 3 (2001) 185-212
    • (2001) Front Neuroendocrinol , vol.22 , Issue.3 , pp. 185-212
    • Labrie, F.1    Luu-The, V.2    Labrie, C.3    Simard, J.4
  • 34
    • 0026579057 scopus 로고
    • Neuroactive steroids
    • Paul S.M., and Purdy R.H. Neuroactive steroids. FASEB J 6 6 (1992) 2311-2322
    • (1992) FASEB J , vol.6 , Issue.6 , pp. 2311-2322
    • Paul, S.M.1    Purdy, R.H.2
  • 35
    • 0029549524 scopus 로고
    • Neurosteroids: biosynthesis and function
    • Robel P., and Baulieu E.E. Neurosteroids: biosynthesis and function. Crit Rev Neurobiol 9 4 (1995) 383-394
    • (1995) Crit Rev Neurobiol , vol.9 , Issue.4 , pp. 383-394
    • Robel, P.1    Baulieu, E.E.2
  • 36
    • 0035206892 scopus 로고    scopus 로고
    • Neurosteroid metabolism in the brain
    • Stoffel-Wagner B. Neurosteroid metabolism in the brain. Eur J Endocrinol 145 6 (2001) 669-679
    • (2001) Eur J Endocrinol , vol.145 , Issue.6 , pp. 669-679
    • Stoffel-Wagner, B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.