-
1
-
-
33644826707
-
Crohn's disease in mainland China: A systematic analysis of 50 years of research
-
Zheng JJ, Zhu XS, Huangfu Z, Gao ZX, Guo ZR, Wang Z. Crohn's disease in mainland China: a systematic analysis of 50 years of research. Chin J Dig Dis 2005; 6: 175-181
-
(2005)
Chin J Dig Dis
, vol.6
, pp. 175-181
-
-
Zheng, J.J.1
Zhu, X.S.2
Huangfu, Z.3
Gao, Z.X.4
Guo, Z.R.5
Wang, Z.6
-
2
-
-
34248136828
-
Inflammatory bowel disease: Cause and immunobiology
-
Baumgart DC, Carding SR. Inflammatory bowel disease: cause and immunobiology. Lancet 2007; 369: 1627-1640
-
(2007)
Lancet
, vol.369
, pp. 1627-1640
-
-
Baumgart, D.C.1
Carding, S.R.2
-
3
-
-
27644493346
-
The pleiotropic role of autophagy: From protein metabolism to bactericide
-
Mizushima N. The pleiotropic role of autophagy: from protein metabolism to bactericide. Cell Death Differ 2005; 12 Suppl 2: 1535-1541
-
(2005)
Cell Death Differ
, vol.12
, Issue.SUPPL. 2
, pp. 1535-1541
-
-
Mizushima, N.1
-
4
-
-
24744463111
-
Autophagy in innate and adaptive immunity
-
Deretic V. Autophagy in innate and adaptive immunity. Trends Immunol 2005; 26: 523-528
-
(2005)
Trends Immunol
, vol.26
, pp. 523-528
-
-
Deretic, V.1
-
5
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
Hampe J, Franke A, Rosenstiel P, Till A, Teuber M, Huse K, Albrecht M, Mayr G, De La Vega FM, Briggs J, Günther S, Prescott NJ, Onnie CM, Häsler R, Sipos B, Fölsch UR, Lengauer T, Platzer M, Mathew CG, Krawczak M, Schreiber S. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet 2007; 39: 207-211
-
(2007)
Nat Genet
, vol.39
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
Till, A.4
Teuber, M.5
Huse, K.6
Albrecht, M.7
Mayr, G.8
De La Vega, F.M.9
Briggs, J.10
Günther, S.11
Prescott, N.J.12
Onnie, C.M.13
Häsler, R.14
Sipos, B.15
Fölsch, U.R.16
Lengauer, T.17
Platzer, M.18
Mathew, C.G.19
Krawczak, M.20
Schreiber, S.21
more..
-
6
-
-
34547211759
-
Association of the T300A non-synonymous variant of the ATG16L1 gene with susceptibility to paediatric Crohn's disease
-
Baldassano RN, Bradfield JP, Monos DS, Kim CE, Glessner JT, Casalunovo T, Frackelton EC, Otieno FG, Kanterakis S, Shaner JL, Smith RM, Eckert AW, Robinson LJ, Onyiah CC, Abrams DJ, Chiavacci RM, Skraban R, Devoto M, Grant SF, Hakonarson H. Association of the T300A non-synonymous variant of the ATG16L1 gene with susceptibility to paediatric Crohn's disease. Gut 2007; 56: 1171-1173
-
(2007)
Gut
, vol.56
, pp. 1171-1173
-
-
Baldassano, R.N.1
Bradfield, J.P.2
Monos, D.S.3
Kim, C.E.4
Glessner, J.T.5
Casalunovo, T.6
Frackelton, E.C.7
Otieno, F.G.8
Kanterakis, S.9
Shaner, J.L.10
Smith, R.M.11
Eckert, A.W.12
Robinson, L.J.13
Onyiah, C.C.14
Abrams, D.J.15
Chiavacci, R.M.16
Skraban, R.17
Devoto, M.18
Grant, S.F.19
Hakonarson, H.20
more..
-
7
-
-
37249054533
-
A study in three European IBD cohorts confirms that the ATG16L1 c.898A>G (p.Thr300Ala) variant is a susceptibility factor for Crohn's disease
-
Büning C, Durmus T, Molnar T, de Jong DJ., Drenth JPH., Fiedler T, Gentz E, Todorov T, Haas V, Buhner S, Sturm A. Baumgart DC., Nagy F, Lonovics J, Landt O, Kage A, Büning H, Nickel R, Büttner J, Lochs H, Schmidt HH-J, Witt H. A study in three European IBD cohorts confirms that the ATG16L1 c.898A>G (p.Thr300Ala) variant is a susceptibility factor for Crohn's disease. J Crohn's Colitis 2007; 1: 70-76
-
(2007)
J Crohn's Colitis
, vol.1
, pp. 70-76
-
-
Büning, C.1
Durmus, T.2
Molnar, T.3
de Jong, D.J.4
Drenth, J.P.H.5
Fiedler, T.6
Gentz, E.7
Todorov, T.8
Haas, V.9
Buhner, S.10
Sturm, A.11
Baumgart, D.C.12
Nagy, F.13
Lonovics, J.14
Landt, O.15
Kage, A.16
Büning, H.17
Nickel, R.18
Büttner, J.19
Lochs, H.20
Schmidt, H.H.-J.21
Witt, H.22
more..
-
8
-
-
34548163868
-
Confirmation of the role of ATG16L1 as a Crohn's disease susceptibility gene
-
Cummings JR, Cooney R, Pathan S, Anderson CA, Barrett JC, Beckly J, Geremia A, Hancock L, Guo C, Ahmad T, Cardon LR, Jewell DP. Confirmation of the role of ATG16L1 as a Crohn's disease susceptibility gene. Inflamm Bowel Dis 2007; 13: 941-946
-
(2007)
Inflamm Bowel Dis
, vol.13
, pp. 941-946
-
-
Cummings, J.R.1
Cooney, R.2
Pathan, S.3
Anderson, C.A.4
Barrett, J.C.5
Beckly, J.6
Geremia, A.7
Hancock, L.8
Guo, C.9
Ahmad, T.10
Cardon, L.R.11
Jewell, D.P.12
-
9
-
-
34247566585
-
A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5
-
Prescott NJ, Fisher SA, Franke A, Hampe J, Onnie CM, Soars D, Bagnall R, Mirza MM, Sanderson J, Forbes A, Mansfield JC, Lewis CM, Schreiber S, Mathew CG. A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5. Gastroenterology 2007; 132: 1665-1671
-
(2007)
Gastroenterology
, vol.132
, pp. 1665-1671
-
-
Prescott, N.J.1
Fisher, S.A.2
Franke, A.3
Hampe, J.4
Onnie, C.M.5
Soars, D.6
Bagnall, R.7
Mirza, M.M.8
Sanderson, J.9
Forbes, A.10
Mansfield, J.C.11
Lewis, C.M.12
Schreiber, S.13
Mathew, C.G.14
-
10
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, Green T, Kuballa P, Barmada MM, Datta LW, Shugart YY, Griffiths AM, Targan SR, Ippoliti AF, Bernard EJ, Mei L, Nicolae DL, Regueiro M, Schumm LP, Steinhart AH, Rotter JI, Duerr RH, Cho JH, Daly MJ, Brant SR. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 2007; 39: 596-604
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
Silverberg, M.S.4
Goyette, P.5
Huett, A.6
Green, T.7
Kuballa, P.8
Barmada, M.M.9
Datta, L.W.10
Shugart, Y.Y.11
Griffiths, A.M.12
Targan, S.R.13
Ippoliti, A.F.14
Bernard, E.J.15
Mei, L.16
Nicolae, D.L.17
Regueiro, M.18
Schumm, L.P.19
Steinhart, A.H.20
Rotter, J.I.21
Duerr, R.H.22
Cho, J.H.23
Daly, M.J.24
Brant, S.R.25
more..
-
11
-
-
36549062442
-
IL23R R381Q and ATG16L1 T300A are strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease
-
Roberts RL, Gearry RB, Hollis-Moffatt JE, Miller AL, Reid J, Abkevich V, Timms KM, Gutin A, Lanchbury JS, Merriman TR, Barclay ML, Kennedy MA. IL23R R381Q and ATG16L1 T300A are strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease. Am J Gastroenterol 2007; 102: 2754-2761
-
(2007)
Am J Gastroenterol
, vol.102
, pp. 2754-2761
-
-
Roberts, R.L.1
Gearry, R.B.2
Hollis-Moffatt, J.E.3
Miller, A.L.4
Reid, J.5
Abkevich, V.6
Timms, K.M.7
Gutin, A.8
Lanchbury, J.S.9
Merriman, T.R.10
Barclay, M.L.11
Kennedy, M.A.12
-
12
-
-
34347357508
-
Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients
-
Yamazaki K, Onouchi Y, Takazoe M, Kubo M, Nakamura Y, Hata A. Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients. J Hum Genet 2007; 52: 575-583
-
(2007)
J Hum Genet
, vol.52
, pp. 575-583
-
-
Yamazaki, K.1
Onouchi, Y.2
Takazoe, M.3
Kubo, M.4
Nakamura, Y.5
Hata, A.6
-
13
-
-
67349233285
-
Autophagy gene ATG16L1 but not IRGM is associated with Crohn's disease in Canadian children
-
Amre DK, Mack DR, Morgan K, Krupoves A, Costea I, Lambrette P, Grimard G, Dong J, Feguery H, Bucionis V, Deslandres C, Levy E, Seidman EG. Autophagy gene ATG16L1 but not IRGM is associated with Crohn's disease in Canadian children. Inflamm Bowel Dis 2009; 15: 501-507
-
(2009)
Inflamm Bowel Dis
, vol.15
, pp. 501-507
-
-
Amre, D.K.1
Mack, D.R.2
Morgan, K.3
Krupoves, A.4
Costea, I.5
Lambrette, P.6
Grimard, G.7
Dong, J.8
Feguery, H.9
Bucionis, V.10
Deslandres, C.11
Levy, E.12
Seidman, E.G.13
-
14
-
-
44349154771
-
CARD15 and IL23R influences Crohn's disease susceptibility but not disease phenotype in a Brazilian population
-
Baptista ML, Amarante H, Picheth G, Sdepanian VL, Peterson N, Babasukumar U, Lima HC, Kugathasan S. CARD15 and IL23R influences Crohn's disease susceptibility but not disease phenotype in a Brazilian population. Inflamm Bowel Dis 2008; 14: 674-679
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 674-679
-
-
Baptista, M.L.1
Amarante, H.2
Picheth, G.3
Sdepanian, V.L.4
Peterson, N.5
Babasukumar, U.6
Lima, H.C.7
Kugathasan, S.8
-
15
-
-
53149144667
-
ATG16L1 T300A shows strong associations with disease subgroups in a large Australian IBD population: Further support for significant disease heterogeneity
-
Fowler EV, Doecke J, Simms LA, Zhao ZZ, Webb PM, Hayward NK, Whiteman DC, Florin TH, Montgomery GW, Cavanaugh JA, Radford-Smith GL. ATG16L1 T300A shows strong associations with disease subgroups in a large Australian IBD population: further support for significant disease heterogeneity. Am J Gastroenterol 2008; 103: 2519-2526
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 2519-2526
-
-
Fowler, E.V.1
Doecke, J.2
Simms, L.A.3
Zhao, Z.Z.4
Webb, P.M.5
Hayward, N.K.6
Whiteman, D.C.7
Florin, T.H.8
Montgomery, G.W.9
Cavanaugh, J.A.10
Radford-Smith, G.L.11
-
16
-
-
52049083069
-
Lack of evidence for association of primary sclerosing cholangitis and primary biliary cirrhosis with risk alleles for Crohn's disease in Polish patients
-
Gaj P, Habior A, Mikula M, Ostrowski J. Lack of evidence for association of primary sclerosing cholangitis and primary biliary cirrhosis with risk alleles for Crohn's disease in Polish patients. BMC Med Genet 2008; 9: 81
-
(2008)
BMC Med Genet
, vol.9
, pp. 81
-
-
Gaj, P.1
Habior, A.2
Mikula, M.3
Ostrowski, J.4
-
17
-
-
40949112379
-
The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population
-
Glas J, Konrad A, Schmechel S, Dambacher J, Seiderer J, Schroff F, Wetzke M, Roeske D, Török HP, Tonenchi L, Pfennig S, Haller D, Griga T, Klein W, Epplen JT, Folwaczny C, Lohse P, Göke B, Ochsenkühn T, Mussack T, Folwaczny M, Müller-Myhsok B, Brand S. The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population. Am J Gastroenterol 2008; 103: 682-691
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 682-691
-
-
Glas, J.1
Konrad, A.2
Schmechel, S.3
Dambacher, J.4
Seiderer, J.5
Schroff, F.6
Wetzke, M.7
Roeske, D.8
Török, H.P.9
Tonenchi, L.10
Pfennig, S.11
Haller, D.12
Griga, T.13
Klein, W.14
Epplen, J.T.15
Folwaczny, C.16
Lohse, P.17
Göke, B.18
Ochsenkühn, T.19
Mussack, T.20
Folwaczny, M.21
Müller-Myhsok, B.22
Brand, S.23
more..
-
18
-
-
52749086232
-
ATG16L1 and IL23 receptor (IL23R) genes are associated with disease susceptibility in Hungarian CD patients
-
Lakatos PL, Szamosi T, Szilvasi A, Molnar E, Lakatos L, Kovacs A, Molnar T, Altorjay I, Papp M, Tulassay Z, Miheller P, Papp J, Tordai A, Andrikovics H. ATG16L1 and IL23 receptor (IL23R) genes are associated with disease susceptibility in Hungarian CD patients. Dig Liver Dis 2008; 40: 867-873
-
(2008)
Dig Liver Dis
, vol.40
, pp. 867-873
-
-
Lakatos, P.L.1
Szamosi, T.2
Szilvasi, A.3
Molnar, E.4
Lakatos, L.5
Kovacs, A.6
Molnar, T.7
Altorjay, I.8
Papp, M.9
Tulassay, Z.10
Miheller, P.11
Papp, J.12
Tordai, A.13
Andrikovics, H.14
-
19
-
-
49749098522
-
Association of IL23R, TNFRSF1A, and HLA-DRB1*0103 allele variants with inflammatory bowel disease phenotypes in the Finnish population
-
Lappalainen M, Halme L, Turunen U, Saavalainen P, Einarsdottir E, Färkkilä M, Kontula K, Paavola-Sakki P. Association of IL23R, TNFRSF1A, and HLA-DRB1*0103 allele variants with inflammatory bowel disease phenotypes in the Finnish population. Inflamm Bowel Dis 2008; 14: 1118-1124
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 1118-1124
-
-
Lappalainen, M.1
Halme, L.2
Turunen, U.3
Saavalainen, P.4
Einarsdottir, E.5
Färkkilä, M.6
Kontula, K.7
Paavola-Sakki, P.8
-
20
-
-
58149201215
-
Replication of interleukin 23 receptor and autophagy-related 16-like 1 association in adult- and pediatric-onset inflammatory bowel disease in Italy
-
Latiano A, Palmieri O, Valvano MR, D'Incà R, Cucchiara S, Riegler G, Staiano AM, Ardizzone S, Accomando S, de Angelis GL, Corritore G, Bossa F, Annese V. Replication of interleukin 23 receptor and autophagy-related 16-like 1 association in adult- and pediatric-onset inflammatory bowel disease in Italy. World J Gastroenterol 2008; 14: 4643-4651
-
(2008)
World J Gastroenterol
, vol.14
, pp. 4643-4651
-
-
Latiano, A.1
Palmieri, O.2
Valvano, M.R.3
D'Incà, R.4
Cucchiara, S.5
Riegler, G.6
Staiano, A.M.7
Ardizzone, S.8
Accomando, S.9
de Angelis, G.L.10
Corritore, G.11
Bossa, F.12
Annese, V.13
-
21
-
-
58849165225
-
Contributions of IBD5, IL23R, ATG16L1, and NOD2 to Crohn's disease risk in a population-based case-control study: Evidence of genegene interactions
-
Okazaki T, Wang MH, Rawsthorne P, Sargent M, Datta LW, Shugart YY, Bernstein CN, Brant SR. Contributions of IBD5, IL23R, ATG16L1, and NOD2 to Crohn's disease risk in a population-based case-control study: evidence of genegene interactions. Inflamm Bowel Dis 2008; 14: 1528-1541
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 1528-1541
-
-
Okazaki, T.1
Wang, M.H.2
Rawsthorne, P.3
Sargent, M.4
Datta, L.W.5
Shugart, Y.Y.6
Bernstein, C.N.7
Brant, S.R.8
-
22
-
-
37349017533
-
ATG16L1 Ala197Thr is not associated with susceptibility to Crohn's disease or with phenotype in an Italian population
-
Perricone C, Borgiani P, Romano S, Ciccacci C, Fusco G, Novelli G, Biancone L, Calabrese E, Pallone F. ATG16L1 Ala197Thr is not associated with susceptibility to Crohn's disease or with phenotype in an Italian population. Gastroenterology 2008; 134: 368-370
-
(2008)
Gastroenterology
, vol.134
, pp. 368-370
-
-
Perricone, C.1
Borgiani, P.2
Romano, S.3
Ciccacci, C.4
Fusco, G.5
Novelli, G.6
Biancone, L.7
Calabrese, E.8
Pallone, F.9
-
23
-
-
50249133280
-
-
Peterson N, Guthery S, Denson L, Lee J, Saeed S, Prahalad S, Biank V, Ehlert R, Tomer G, Grand R, Rudolph C, Kugathasan S. Genetic variants in the autophagy pathway contribute to paediatric Crohn's disease. Gut 2008; 57: 1336-1337; author reply 1337
-
Peterson N, Guthery S, Denson L, Lee J, Saeed S, Prahalad S, Biank V, Ehlert R, Tomer G, Grand R, Rudolph C, Kugathasan S. Genetic variants in the autophagy pathway contribute to paediatric Crohn's disease. Gut 2008; 57: 1336-1337; author reply 1337
-
-
-
-
24
-
-
41149137717
-
Autophagy gene ATG16L1 influences susceptibility and disease location but not childhood-onset in Crohn's disease in Northern Europe
-
Van Limbergen J, Russell RK, Nimmo ER, Drummond HE, Smith L, Anderson NH, Davies G, Gillett PM, McGrogan P, Weaver LT, Bisset WM, Mahdi G, Arnott ID, Wilson DC, Satsangi J. Autophagy gene ATG16L1 influences susceptibility and disease location but not childhood-onset in Crohn's disease in Northern Europe. Inflamm Bowel Dis 2008; 14: 338-346
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 338-346
-
-
Van Limbergen, J.1
Russell, R.K.2
Nimmo, E.R.3
Drummond, H.E.4
Smith, L.5
Anderson, N.H.6
Davies, G.7
Gillett, P.M.8
McGrogan, P.9
Weaver, L.T.10
Bisset, W.M.11
Mahdi, G.12
Arnott, I.D.13
Wilson, D.C.14
Satsangi, J.15
-
25
-
-
63149135832
-
Correlation of the autophagosome gene ATG16L1 polymorphism and inflammatory bowel disease]
-
Zhi J, Zhi FC, Chen ZY, Yao GP, Guan J, Lin Y, Zhang YC.[Correlation of the autophagosome gene ATG16L1 polymorphism and inflammatory bowel disease] Nanfang Yikedaxue Xuebao 2008; 28: 649-651
-
(2008)
Nanfang Yikedaxue Xuebao
, vol.28
, pp. 649-651
-
-
Zhi, J.1
Zhi, F.C.2
Chen, Z.Y.3
Yao, G.P.4
Guan, J.5
Lin, Y.6
Zhang, Y.C.7
-
26
-
-
61649123125
-
Molecular prediction of disease risk and severity in a large Dutch Crohn's disease cohort
-
Weersma RK, Stokkers PC, van Bodegraven AA, van Hogezand RA, Verspaget HW, de Jong DJ, van der Woude CJ, Oldenburg B, Linskens RK, Festen EA, van der Steege G, Hommes DW, Crusius JB, Wijmenga C, Nolte IM, Dijkstra G. Molecular prediction of disease risk and severity in a large Dutch Crohn's disease cohort. Gut 2009; 58: 388-395
-
(2009)
Gut
, vol.58
, pp. 388-395
-
-
Weersma, R.K.1
Stokkers, P.C.2
van Bodegraven, A.A.3
van Hogezand, R.A.4
Verspaget, H.W.5
de Jong, D.J.6
van der Woude, C.J.7
Oldenburg, B.8
Linskens, R.K.9
Festen, E.A.10
van der Steege, G.11
Hommes, D.W.12
Crusius, J.B.13
Wijmenga, C.14
Nolte, I.M.15
Dijkstra, G.16
-
27
-
-
58849161728
-
Clinical and molecular characteristics of isolated colonic Crohn's disease
-
Hancock L, Beckly J, Geremia A, Cooney R, Cummings F, Pathan S, Guo C, Warren BF, Mortensen N, Ahmad T, Jewell D. Clinical and molecular characteristics of isolated colonic Crohn's disease. Inflamm Bowel Dis 2008; 14: 1667-1677
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 1667-1677
-
-
Hancock, L.1
Beckly, J.2
Geremia, A.3
Cooney, R.4
Cummings, F.5
Pathan, S.6
Guo, C.7
Warren, B.F.8
Mortensen, N.9
Ahmad, T.10
Jewell, D.11
-
28
-
-
70449719062
-
Contribution of IL23R but not ATG16L1 to Crohn's disease susceptibility in Koreans
-
Yang SK, Park M, Lim J, Park SH, Ye BD, Lee I, Song K. Contribution of IL23R but not ATG16L1 to Crohn's disease susceptibility in Koreans. Inflamm Bowel Dis 2009; 15: 1385-1390
-
(2009)
Inflamm Bowel Dis
, vol.15
, pp. 1385-1390
-
-
Yang, S.K.1
Park, M.2
Lim, J.3
Park, S.H.4
Ye, B.D.5
Lee, I.6
Song, K.7
-
29
-
-
67651095721
-
Genetic variants in IL-23R and ATG16L1 independently predispose to increased susceptibility to Crohn's disease in a Canadian population
-
Newman WG, Zhang Q, Liu X, Amos CI, Siminovitch KA. Genetic variants in IL-23R and ATG16L1 independently predispose to increased susceptibility to Crohn's disease in a Canadian population. J Clin Gastroenterol 2009; 43: 444-447
-
(2009)
J Clin Gastroenterol
, vol.43
, pp. 444-447
-
-
Newman, W.G.1
Zhang, Q.2
Liu, X.3
Amos, C.I.4
Siminovitch, K.A.5
-
30
-
-
67349176205
-
ATG16L1 T300A polymorphism and Crohn's disease susceptibility: Evidence from 13,022 cases and 17,532 controls
-
Zhang HF, Qiu LX, Chen Y, Zhu WL, Mao C, Zhu LG, Zheng MH, Wang Y, Lei L, Shi J. ATG16L1 T300A polymorphism and Crohn's disease susceptibility: evidence from 13,022 cases and 17,532 controls. Hum Genet 2009; 125: 627-631
-
(2009)
Hum Genet
, vol.125
, pp. 627-631
-
-
Zhang, H.F.1
Qiu, L.X.2
Chen, Y.3
Zhu, W.L.4
Mao, C.5
Zhu, L.G.6
Zheng, M.H.7
Wang, Y.8
Lei, L.9
Shi, J.10
-
31
-
-
61949327205
-
-
Glas J, Seiderer J, Pasciuto G, Tillack C, Diegelmann J, Pfennig S, Konrad A, Schmechel S, Wetzke M, Török HP, Stallhofer J, Jürgens M, Griga T, Klein W, Epplen JT, Schiemann U, Mussack T, Lohse P, Göke B, Ochsenkühn T, Folwaczny M, Müller-Myhsok B, Brand S. rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population. Am J Gastroenterol 2009; 104: 665-672
-
Glas J, Seiderer J, Pasciuto G, Tillack C, Diegelmann J, Pfennig S, Konrad A, Schmechel S, Wetzke M, Török HP, Stallhofer J, Jürgens M, Griga T, Klein W, Epplen JT, Schiemann U, Mussack T, Lohse P, Göke B, Ochsenkühn T, Folwaczny M, Müller-Myhsok B, Brand S. rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population. Am J Gastroenterol 2009; 104: 665-672
-
-
-
-
32
-
-
67650514274
-
Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease
-
Török HP, Glas J, Endres I, Tonenchi L, Teshome MY, Wetzke M, Klein W, Lohse P, Ochsenkühn T, Folwaczny M, Göke B, Folwaczny C, Müller-Myhsok B, Brand S. Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease. Am J Gastroenterol 2009; 104: 1723-1733
-
(2009)
Am J Gastroenterol
, vol.104
, pp. 1723-1733
-
-
Török, H.P.1
Glas, J.2
Endres, I.3
Tonenchi, L.4
Teshome, M.Y.5
Wetzke, M.6
Klein, W.7
Lohse, P.8
Ochsenkühn, T.9
Folwaczny, M.10
Göke, B.11
Folwaczny, C.12
Müller-Myhsok, B.13
Brand, S.14
-
33
-
-
69449092789
-
Association between genetic variants in myosin IXB and Crohn's disease
-
Cooney R, Cummings JR, Pathan S, Beckly J, Geremia A, Hancock L, Guo C, Morris A, Jewell DP. Association between genetic variants in myosin IXB and Crohn's disease. Inflamm Bowel Dis 2009; 15: 1014-1021
-
(2009)
Inflamm Bowel Dis
, vol.15
, pp. 1014-1021
-
-
Cooney, R.1
Cummings, J.R.2
Pathan, S.3
Beckly, J.4
Geremia, A.5
Hancock, L.6
Guo, C.7
Morris, A.8
Jewell, D.P.9
-
34
-
-
40949105649
-
ATG16L1 and IL23R are associated with inflammatory bowel diseases but not with celiac disease in the Netherlands
-
Weersma RK, Zhernakova A, Nolte IM, Lefebvre C, Rioux JD, Mulder F, van Dullemen HM, Kleibeuker JH, Wijmenga C, Dijkstra G. ATG16L1 and IL23R are associated with inflammatory bowel diseases but not with celiac disease in the Netherlands. Am J Gastroenterol 2008; 103: 621-627
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 621-627
-
-
Weersma, R.K.1
Zhernakova, A.2
Nolte, I.M.3
Lefebvre, C.4
Rioux, J.D.5
Mulder, F.6
van Dullemen, H.M.7
Kleibeuker, J.H.8
Wijmenga, C.9
Dijkstra, G.10
-
35
-
-
62049085384
-
Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort
-
Weersma RK, Stokkers PC, Cleynen I, Wolfkamp SC, Henckaerts L, Schreiber S, Dijkstra G, Franke A, Nolte IM, Rutgeerts P, Wijmenga C, Vermeire S. Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort. Am J Gastroenterol 2009; 104: 630-638
-
(2009)
Am J Gastroenterol
, vol.104
, pp. 630-638
-
-
Weersma, R.K.1
Stokkers, P.C.2
Cleynen, I.3
Wolfkamp, S.C.4
Henckaerts, L.5
Schreiber, S.6
Dijkstra, G.7
Franke, A.8
Nolte, I.M.9
Rutgeerts, P.10
Wijmenga, C.11
Vermeire, S.12
-
36
-
-
37249034766
-
Systematic association mapping identifies NELL1 as a novel IBD disease gene
-
Franke A, Hampe J, Rosenstiel P, Becker C, Wagner F, Häsler R, Little RD, Huse K, Ruether A, Balschun T, Wittig M, Elsharawy A, Mayr G, Albrecht M, Prescott NJ, Onnie CM, Fournier H, Keith T, Radelof U, Platzer M, Mathew CG, Stoll M, Krawczak M, Nürnberg P, Schreiber S. Systematic association mapping identifies NELL1 as a novel IBD disease gene. PLoS One 2007; 2: e691
-
(2007)
PLoS One
, vol.2
-
-
Franke, A.1
Hampe, J.2
Rosenstiel, P.3
Becker, C.4
Wagner, F.5
Häsler, R.6
Little, R.D.7
Huse, K.8
Ruether, A.9
Balschun, T.10
Wittig, M.11
Elsharawy, A.12
Mayr, G.13
Albrecht, M.14
Prescott, N.J.15
Onnie, C.M.16
Fournier, H.17
Keith, T.18
Radelof, U.19
Platzer, M.20
Mathew, C.G.21
Stoll, M.22
Krawczak, M.23
Nürnberg, P.24
Schreiber, S.25
more..
-
37
-
-
44349173654
-
Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis
-
Franke A, Balschun T, Karlsen TH, Hedderich J, May S, Lu T, Schuldt D, Nikolaus S, Rosenstiel P, Krawczak M, Schreiber S. Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis. Nat Genet 2008; 40: 713-715
-
(2008)
Nat Genet
, vol.40
, pp. 713-715
-
-
Franke, A.1
Balschun, T.2
Karlsen, T.H.3
Hedderich, J.4
May, S.5
Lu, T.6
Schuldt, D.7
Nikolaus, S.8
Rosenstiel, P.9
Krawczak, M.10
Schreiber, S.11
-
38
-
-
44349136821
-
-
Fisher SA, Tremelling M, Anderson CA, Gwilliam R, Bumpstead S, Prescott NJ, Nimmo ER, Massey D, Berzuini C, Johnson C, Barrett JC, Cummings FR, Drummond H, Lees CW, Onnie CM, Hanson CE, Blaszczyk K, Inouye M, Ewels P, Ravindrarajah R, Keniry A, Hunt S, Carter M, Watkins N, Ouwehand W, Lewis CM, Cardon L, Lobo A, Forbes A, Sanderson J, Jewell DP, Mansfield JC, Deloukas P, Mathew CG, Parkes M, Satsangi J. Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. Nat Genet 2008; 40: 710-712
-
Fisher SA, Tremelling M, Anderson CA, Gwilliam R, Bumpstead S, Prescott NJ, Nimmo ER, Massey D, Berzuini C, Johnson C, Barrett JC, Cummings FR, Drummond H, Lees CW, Onnie CM, Hanson CE, Blaszczyk K, Inouye M, Ewels P, Ravindrarajah R, Keniry A, Hunt S, Carter M, Watkins N, Ouwehand W, Lewis CM, Cardon L, Lobo A, Forbes A, Sanderson J, Jewell DP, Mansfield JC, Deloukas P, Mathew CG, Parkes M, Satsangi J. Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. Nat Genet 2008; 40: 710-712
-
-
-
-
39
-
-
42449153256
-
Two-stage candidate gene study of chromosome 3p demonstrates an association between nonsynonymous variants in the MST1R gene and Crohn's disease
-
Beckly JB, Hancock L, Geremia A, Cummings JR, Morris A, Cooney R, Pathan S, Guo C, Jewell DP. Two-stage candidate gene study of chromosome 3p demonstrates an association between nonsynonymous variants in the MST1R gene and Crohn's disease. Inflamm Bowel Dis 2008; 14: 500-507
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 500-507
-
-
Beckly, J.B.1
Hancock, L.2
Geremia, A.3
Cummings, J.R.4
Morris, A.5
Cooney, R.6
Pathan, S.7
Guo, C.8
Jewell, D.P.9
-
40
-
-
84969213492
-
000 cases of seven common diseases and 3,000 shared controls
-
Genome-wide association study of 14
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447: 661-678
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
41
-
-
48349136889
-
-
Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmada MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ, Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot JP, de Vos M, Vermeire S, Louis E, Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwilliam R, Tremelling M, Deloukas P, Mansfield J, Jewell D, Satsangi J, Mathew CG, Parkes M, Georges M, Daly MJ. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet 2008; 40: 955-962
-
Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmada MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ, Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot JP, de Vos M, Vermeire S, Louis E, Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwilliam R, Tremelling M, Deloukas P, Mansfield J, Jewell D, Satsangi J, Mathew CG, Parkes M, Georges M, Daly MJ. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet 2008; 40: 955-962
-
-
-
-
42
-
-
34247579326
-
Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4
-
Libioulle C, Louis E, Hansoul S, Sandor C, Farnir F, Franchimont D, Vermeire S, Dewit O, de Vos M, Dixon A, Demarche B, Gut I, Heath S, Foglio M, Liang L, Laukens D, Mni M, Zelenika D, Van Gossum A, Rutgeerts P, Belaiche J, Lathrop M, Georges M. Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. PLoS Genet 2007; 3: e58
-
(2007)
PLoS Genet
, vol.3
-
-
Libioulle, C.1
Louis, E.2
Hansoul, S.3
Sandor, C.4
Farnir, F.5
Franchimont, D.6
Vermeire, S.7
Dewit, O.8
de Vos, M.9
Dixon, A.10
Demarche, B.11
Gut, I.12
Heath, S.13
Foglio, M.14
Liang, L.15
Laukens, D.16
Mni, M.17
Zelenika, D.18
Van Gossum, A.19
Rutgeerts, P.20
Belaiche, J.21
Lathrop, M.22
Georges, M.23
more..
-
43
-
-
34347338690
-
-
Parkes M, Barrett JC, Prescott NJ, Tremelling M, Anderson CA, Fisher SA, Roberts RG, Nimmo ER, Cummings FR, Soars D, Drummond H, Lees CW, Khawaja SA, Bagnall R, Burke DA, Todhunter CE, Ahmad T, Onnie CM, McArdle W, Strachan D, Bethel G, Bryan C, Lewis CM, Deloukas P, Forbes A, Sanderson J, Jewell DP, Satsangi J, Mansfield JC, Cardon L, Mathew CG. Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet 2007; 39: 830-832
-
Parkes M, Barrett JC, Prescott NJ, Tremelling M, Anderson CA, Fisher SA, Roberts RG, Nimmo ER, Cummings FR, Soars D, Drummond H, Lees CW, Khawaja SA, Bagnall R, Burke DA, Todhunter CE, Ahmad T, Onnie CM, McArdle W, Strachan D, Bethel G, Bryan C, Lewis CM, Deloukas P, Forbes A, Sanderson J, Jewell DP, Satsangi J, Mansfield JC, Cardon L, Mathew CG. Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet 2007; 39: 830-832
-
-
-
-
44
-
-
35548958718
-
Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci
-
Raelson JV, Little RD, Ruether A, Fournier H, Paquin B, Van Eerdewegh P, Bradley WE, Croteau P, Nguyen-Huu Q, Segal J, Debrus S, Allard R, Rosenstiel P, Franke A, Jacobs G, Nikolaus S, Vidal JM, Szego P, Laplante N, Clark HF, Paulussen RJ, Hooper JW, Keith TP, Belouchi A, Schreiber S. Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci. Proc Natl Acad Sci USA 2007; 104: 14747-14752
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 14747-14752
-
-
Raelson, J.V.1
Little, R.D.2
Ruether, A.3
Fournier, H.4
Paquin, B.5
Van Eerdewegh, P.6
Bradley, W.E.7
Croteau, P.8
Nguyen-Huu, Q.9
Segal, J.10
Debrus, S.11
Allard, R.12
Rosenstiel, P.13
Franke, A.14
Jacobs, G.15
Nikolaus, S.16
Vidal, J.M.17
Szego, P.18
Laplante, N.19
Clark, H.F.20
Paulussen, R.J.21
Hooper, J.W.22
Keith, T.P.23
Belouchi, A.24
Schreiber, S.25
more..
-
45
-
-
58849111798
-
Positive association of genetic variants in the upstream region of NKX2-3 with Crohn's disease in Japanese patients
-
Yamazaki K, Takahashi A, Takazoe M, Kubo M, Onouchi Y, Fujino A, Kamatani N, Nakamura Y, Hata A. Positive association of genetic variants in the upstream region of NKX2-3 with Crohn's disease in Japanese patients. Gut 2009; 58: 228-232
-
(2009)
Gut
, vol.58
, pp. 228-232
-
-
Yamazaki, K.1
Takahashi, A.2
Takazoe, M.3
Kubo, M.4
Onouchi, Y.5
Fujino, A.6
Kamatani, N.7
Nakamura, Y.8
Hata, A.9
-
46
-
-
52949091918
-
Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease
-
Kugathasan S, Baldassano RN, Bradfield JP, Sleiman PM, Imielinski M, Guthery SL, Cucchiara S, Kim CE, Frackelton EC, Annaiah K, Glessner JT, Santa E, Willson T, Eckert AW, Bonkowski E, Shaner JL, Smith RM, Otieno FG, Peterson N, Abrams DJ, Chiavacci RM, Grundmeier R, Mamula P, Tomer G, Piccoli DA, Monos DS, Annese V, Denson LA, Grant SF, Hakonarson H. Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease. Nat Genet 2008; 40: 1211-1215
-
(2008)
Nat Genet
, vol.40
, pp. 1211-1215
-
-
Kugathasan, S.1
Baldassano, R.N.2
Bradfield, J.P.3
Sleiman, P.M.4
Imielinski, M.5
Guthery, S.L.6
Cucchiara, S.7
Kim, C.E.8
Frackelton, E.C.9
Annaiah, K.10
Glessner, J.T.11
Santa, E.12
Willson, T.13
Eckert, A.W.14
Bonkowski, E.15
Shaner, J.L.16
Smith, R.M.17
Otieno, F.G.18
Peterson, N.19
Abrams, D.J.20
Chiavacci, R.M.21
Grundmeier, R.22
Mamula, P.23
Tomer, G.24
Piccoli, D.A.25
Monos, D.S.26
Annese, V.27
Denson, L.A.28
Grant, S.F.29
Hakonarson, H.30
more..
-
47
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ, Steinhart AH, Abraham C, Regueiro M, Griffiths A, Dassopoulos T, Bitton A, Yang H, Targan S, Datta LW, Kistner EO, Schumm LP, Lee AT, Gregersen PK, Barmada MM, Rotter JI, Nicolae DL, Cho JH. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 2006; 314: 1461-1463
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
Rioux, J.D.4
Silverberg, M.S.5
Daly, M.J.6
Steinhart, A.H.7
Abraham, C.8
Regueiro, M.9
Griffiths, A.10
Dassopoulos, T.11
Bitton, A.12
Yang, H.13
Targan, S.14
Datta, L.W.15
Kistner, E.O.16
Schumm, L.P.17
Lee, A.T.18
Gregersen, P.K.19
Barmada, M.M.20
Rotter, J.I.21
Nicolae, D.L.22
Cho, J.H.23
more..
-
48
-
-
36749081017
-
Pediatric inflammatory bowel disease: Clinical and molecular genetics
-
Biank V, Broeckel U, Kugathasan S. Pediatric inflammatory bowel disease: clinical and molecular genetics. Inflamm Bowel Dis 2007; 13: 1430-1438
-
(2007)
Inflamm Bowel Dis
, vol.13
, pp. 1430-1438
-
-
Biank, V.1
Broeckel, U.2
Kugathasan, S.3
-
49
-
-
34250804761
-
Progress in basic inflammatory bowel disease research
-
Kugathasan S, Fiocchi C. Progress in basic inflammatory bowel disease research. Semin Pediatr Surg 2007; 16: 146-153
-
(2007)
Semin Pediatr Surg
, vol.16
, pp. 146-153
-
-
Kugathasan, S.1
Fiocchi, C.2
-
50
-
-
34249886868
-
CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease
-
Barnich N, Carvalho FA, Glasser AL, Darcha C, Jantscheff P, Allez M, Peeters H, Bommelaer G, Desreumaux P, Colombel JF, Darfeuille-Michaud A. CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease. J Clin Invest 2007; 117: 1566-1574
-
(2007)
J Clin Invest
, vol.117
, pp. 1566-1574
-
-
Barnich, N.1
Carvalho, F.A.2
Glasser, A.L.3
Darcha, C.4
Jantscheff, P.5
Allez, M.6
Peeters, H.7
Bommelaer, G.8
Desreumaux, P.9
Colombel, J.F.10
Darfeuille-Michaud, A.11
-
51
-
-
0031758230
-
Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease
-
Darfeuille-Michaud A, Neut C, Barnich N, Lederman E, Di Martino P, Desreumaux P, Gambiez L, Joly B, Cortot A, Colombel JF. Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease. Gastroenterology 1998; 115: 1405-1413
-
(1998)
Gastroenterology
, vol.115
, pp. 1405-1413
-
-
Darfeuille-Michaud, A.1
Neut, C.2
Barnich, N.3
Lederman, E.4
Di Martino, P.5
Desreumaux, P.6
Gambiez, L.7
Joly, B.8
Cortot, A.9
Colombel, J.F.10
-
53
-
-
36249025723
-
Autophagy: Process and function
-
Mizushima N. Autophagy: process and function. Genes Dev 2007; 21: 2861-2873
-
(2007)
Genes Dev
, vol.21
, pp. 2861-2873
-
-
Mizushima, N.1
-
54
-
-
34548700796
-
Unveiling the roles of autophagy in innate and adaptive immunity
-
Levine B, Deretic V. Unveiling the roles of autophagy in innate and adaptive immunity. Nat Rev Immunol 2007; 7: 767-777
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 767-777
-
-
Levine, B.1
Deretic, V.2
-
55
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
-
Saitoh T, Fujita N, Jang MH, Uematsu S, Yang BG, Satoh T, Omori H, Noda T, Yamamoto N, Komatsu M, Tanaka K, Kawai T, Tsujimura T, Takeuchi O, Yoshimori T, Akira S. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature 2008; 456: 264-268
-
(2008)
Nature
, vol.456
, pp. 264-268
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
Uematsu, S.4
Yang, B.G.5
Satoh, T.6
Omori, H.7
Noda, T.8
Yamamoto, N.9
Komatsu, M.10
Tanaka, K.11
Kawai, T.12
Tsujimura, T.13
Takeuchi, O.14
Yoshimori, T.15
Akira, S.16
-
56
-
-
56249135538
-
-
Cadwell K, Liu JY, Brown SL, Miyoshi H, Loh J, Lennerz JK, Kishi C, Kc W, Carrero JA, Hunt S, Stone CD, Brunt EM, Xavier RJ, Sleckman BP, Li E, Mizushima N, Stappenbeck TS, Virgin HW 4th. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature 2008; 456: 259-263
-
Cadwell K, Liu JY, Brown SL, Miyoshi H, Loh J, Lennerz JK, Kishi C, Kc W, Carrero JA, Hunt S, Stone CD, Brunt EM, Xavier RJ, Sleckman BP, Li E, Mizushima N, Stappenbeck TS, Virgin HW 4th. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature 2008; 456: 259-263
-
-
-
-
57
-
-
44149123849
-
Autophagy as an important process in gut homeostasis and Crohn's disease pathogenesis
-
Xavier RJ, Huett A, Rioux JD. Autophagy as an important process in gut homeostasis and Crohn's disease pathogenesis. Gut 2008; 57: 717-720
-
(2008)
Gut
, vol.57
, pp. 717-720
-
-
Xavier, R.J.1
Huett, A.2
Rioux, J.D.3
-
58
-
-
54849421128
-
Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant
-
Kuballa P, Huett A, Rioux JD, Daly MJ, Xavier RJ. Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant. PLoS One 2008; 3: e3391
-
(2008)
PLoS One
, vol.3
-
-
Kuballa, P.1
Huett, A.2
Rioux, J.D.3
Daly, M.J.4
Xavier, R.J.5
-
59
-
-
65249187333
-
Enhancing immunity through autophagy
-
Münz C. Enhancing immunity through autophagy. Annu Rev Immunol 2009; 27: 423-449
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 423-449
-
-
Münz, C.1
-
60
-
-
4344700784
-
Downregulation of epithelial apoptosis and barrier repair in active Crohn's disease by tumour necrosis factor alpha antibody treatment
-
Zeissig S, Bojarski C, Buergel N, Mankertz J, Zeitz M, Fromm M, Schulzke JD. Downregulation of epithelial apoptosis and barrier repair in active Crohn's disease by tumour necrosis factor alpha antibody treatment. Gut 2004; 53: 1295-1302
-
(2004)
Gut
, vol.53
, pp. 1295-1302
-
-
Zeissig, S.1
Bojarski, C.2
Buergel, N.3
Mankertz, J.4
Zeitz, M.5
Fromm, M.6
Schulzke, J.D.7
-
61
-
-
0033011679
-
Lamina propria T cells in Crohn's disease and other gastrointestinal inflammation show defective CD2 pathway-induced apoptosis
-
Boirivant M, Marini M, Di Felice G, Pronio AM, Montesani C, Tersigni R, Strober W. Lamina propria T cells in Crohn's disease and other gastrointestinal inflammation show defective CD2 pathway-induced apoptosis. Gastroenterology 1999; 116: 557-565
-
(1999)
Gastroenterology
, vol.116
, pp. 557-565
-
-
Boirivant, M.1
Marini, M.2
Di Felice, G.3
Pronio, A.M.4
Montesani, C.5
Tersigni, R.6
Strober, W.7
-
62
-
-
0036939333
-
Systemic and local evidence of increased Fas-mediated apoptosis in ulcerative colitis
-
Yukawa M, Iizuka M, Horie Y, Yoneyama K, Shirasaka T, Itou H, Komatsu M, Fukushima T, Watanabe S. Systemic and local evidence of increased Fas-mediated apoptosis in ulcerative colitis. Int J Colorectal Dis 2002; 17: 70-76
-
(2002)
Int J Colorectal Dis
, vol.17
, pp. 70-76
-
-
Yukawa, M.1
Iizuka, M.2
Horie, Y.3
Yoneyama, K.4
Shirasaka, T.5
Itou, H.6
Komatsu, M.7
Fukushima, T.8
Watanabe, S.9
-
63
-
-
34347348320
-
The Bcl-2/Bax system and apoptosis in ulcerative colitis
-
Karamanolis DG, Kyrlagkitsis I, Konstantinou K, Papatheodoridis GV, Karameris A, Mallas E, Ladas SD, Raptis S. The Bcl-2/Bax system and apoptosis in ulcerative colitis. Hepatogastroenterology 2007; 54: 1085-1088
-
(2007)
Hepatogastroenterology
, vol.54
, pp. 1085-1088
-
-
Karamanolis, D.G.1
Kyrlagkitsis, I.2
Konstantinou, K.3
Papatheodoridis, G.V.4
Karameris, A.5
Mallas, E.6
Ladas, S.D.7
Raptis, S.8
|