메뉴 건너뛰기




Volumn 6, Issue 2, 2010, Pages 217-228

Prognostic role of metabolic syndrome in the elderly is not greater than the sum of its components

Author keywords

Cardiovascular risk; Elderly; Epidemiology; Hypertension; Metabolic syndrome

Indexed keywords

ANTIHYPERTENSIVE AGENT; FATTY ACID; GLITAZONE DERIVATIVE; GLUCAGON LIKE PEPTIDE 1; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; METFORMIN; TRIACYLGLYCEROL;

EID: 77950121331     PISSN: 1745509X     EISSN: 17455103     Source Type: Journal    
DOI: 10.2217/ahe.10.9     Document Type: Review
Times cited : (5)

References (96)
  • 1
    • 0842277242 scopus 로고    scopus 로고
    • Definition of metabolic syndrome: Report of the national heart lung, and blood institute/American heart association conference on scientific issues related to definition
    • Grundy SM, Brewer BH Jr, Cleeman JI, Smith SC Jr, Lenfant C: Definition of metabolic syndrome: report of the National Heart, Lung, and Blood Institute/American Heart Association Conference on Scientific Issues Related to Definition. Circulation 109, 433-438 (2004).
    • (2004) Circulation , vol.109 , pp. 433-438
    • Grundy, S.M.1    Brewer Jr., B.H.2    Cleeman, J.I.3    Smith Jr., S.C.4    Lenfant, C.5
  • 2
    • 34247518244 scopus 로고    scopus 로고
    • Metabolic syndrome, or what you will: Definitions and epidemiology
    • Day C: Metabolic syndrome, or what you will: definitions and epidemiology. Diab. Vasc. Dis. Res. 4, 32-38 (2007).
    • (2007) Diab. Vasc. Dis. Res. , vol.4 , pp. 32-38
    • Day, C.1
  • 3
    • 34848894602 scopus 로고    scopus 로고
    • The metabolic syndrome and risk of cardiovascular disease and diabetes: Experiences with the new diagnostic criteria from the international diabetes federation
    • Saely CH, Rein P, Drexel H: The metabolic syndrome and risk of cardiovascular disease and diabetes: experiences with the new diagnostic criteria from the International Diabetes Federation. Horm. Metab. Res. 39, 642-650 (2007).
    • (2007) Horm. Metab. Res. , vol.39 , pp. 642-650
    • Saely, C.H.1    Rein, P.2    Drexel, H.3
  • 5
    • 33645503282 scopus 로고
    • Hypertension and diabetes
    • Kylin E: Hypertension and diabetes. Zentralblatt Innere Med. 42, 873-877 (1921).
    • (1921) Zentralblatt Innere Med. , vol.42 , pp. 873-877
    • Kylin, E.1
  • 6
    • 0000377053 scopus 로고
    • Severe hypertension and diabetes
    • Marañon G: Severe hypertension and diabetes. Zentralblatt Innere Med. 43, 169-176 (1922).
    • (1922) Zentralblatt Innere Med. , vol.43 , pp. 169-176
    • Marañon, G.1
  • 7
    • 0000939795 scopus 로고
    • Studies in the hypertension- Hyperglycemia-hyperuricemia syndrome
    • Kylin E: Studies in the hypertension- hyperglycemia-hyperuricemia syndrome. Zentralblatt Innere Med. 44, 105-127 (1923).
    • (1923) Zentralblatt Innere Med. , vol.44 , pp. 105-127
    • Kylin, E.1
  • 8
    • 0001217241 scopus 로고
    • Sexual differentiation, a determining factor in obesity classes
    • Vague J: Sexual differentiation, a determining factor in obesity classes. Presse Med. 30, 339-340 (1947).
    • (1947) Presse Med. , vol.30 , pp. 339-340
    • Vague, J.1
  • 9
    • 0013203891 scopus 로고
    • Association of hiperlipidemia, diabetes mellitus and moderate obesity
    • Avogaro P, Crepaldi G, Enzi G, Tiengo A: Association of hiperlipidemia, diabetes mellitus and moderate obesity. Acta Diabetol. Lat. 4, 36-41 (1967).
    • (1967) Acta Diabetol. Lat. , vol.4 , pp. 36-41
    • Avogaro, P.1    Crepaldi, G.2    Enzi, G.3    Tiengo, A.4
  • 10
    • 0024160877 scopus 로고
    • Banting lecture. Role of insulin resistance in human disease
    • Reaven GM: Banting lecture. Role of insulin resistance in human disease. Diabetes 37, 1595-1607 (1988).
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 11
    • 33644898538 scopus 로고    scopus 로고
    • Metabolic syndrome: Connecting and reconciling cardiovascular and diabetes worlds
    • Grundy SM: Metabolic syndrome: Connecting and reconciling cardiovascular and diabetes worlds. J. Am. Coll. Cardiol. 47, 1093-1100 (2006).
    • (2006) J. Am. Coll. Cardiol. , vol.47 , pp. 1093-1100
    • Grundy, S.M.1
  • 12
    • 33745603792 scopus 로고    scopus 로고
    • The metabolic syndrome: Is this diagnosis necessary?
    • Reaven GM: The metabolic syndrome: is this diagnosis necessary? Am. J. Clin. Nutr. 83, 1237-1247 (2006).
    • (2006) Am. J. Clin. Nutr. , vol.83 , pp. 1237-1247
    • Reaven, G.M.1
  • 13
    • 19644394512 scopus 로고    scopus 로고
    • The metabolic syndrome: Requiescat in pace
    • Reaven GM: The metabolic syndrome: requiescat in pace. Clin. Chem. 51, 931-938 (2005).
    • (2005) Clin. Chem. , vol.51 , pp. 931-938
    • Reaven, G.M.1
  • 14
    • 24144484876 scopus 로고    scopus 로고
    • The metabolic syndrome: Time for a critical appraisal: Joint statement from the American diabetes association and the European association for the study of diabetes
    • Kahn R, Buse J, Ferrannini E, Stern M: The metabolic syndrome: time for a critical appraisal: joint statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 28, 2289-2304 (2005).
    • (2005) Diabetes Care , vol.28 , pp. 2289-2304
    • Kahn, R.1    Buse, J.2    Ferrannini, E.3    Stern, M.4
  • 15
    • 23944444300 scopus 로고    scopus 로고
    • Health consequences of obesity in the elderly: A review of four unresolved questions
    • Zamboni M, Mazzali G, Zoico E et al.: Health consequences of obesity in the elderly: a review of four unresolved questions. Int. J. Obes. 29, 1011-1029 (2005).
    • (2005) Int. J. Obes. , vol.29 , pp. 1011-1029
    • Zamboni, M.1    Mazzali, G.2    Zoico, E.3
  • 16
    • 66349094677 scopus 로고    scopus 로고
    • Metabolic syndrome: At the crossroads of cardiorenal risk
    • Natali A, Pucci G, Boldrini B, Schillaci G: Metabolic syndrome: at the crossroads of cardiorenal risk. J. Nephrol. 22, 29-38 (2009).
    • (2009) J. Nephrol. , vol.22 , pp. 29-38
    • Natali, A.1    Pucci, G.2    Boldrini, B.3    Schillaci, G.4
  • 17
    • 0037126526 scopus 로고    scopus 로고
    • Third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) final report
    • National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III): Third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 106, 3143-11421(2002).
    • (2002) Circulation , vol.106 , pp. 3143-11421
  • 18
    • 70449517507 scopus 로고    scopus 로고
    • Increased mortality in the slim elderly: A 42 years follow-up study in a general population
    • Gulsvik AK, Thelle DS, Mowé M, Wyller TB: Increased mortality in the slim elderly: a 42 years follow-up study in a general population. Eur. J. Epidemiol. 24(11), 683-690 (2009).
    • (2009) Eur. J. Epidemiol. , vol.24 , Issue.11 , pp. 683-690
    • Gulsvik, A.K.1    Thelle, D.S.2    Mowé, M.3    Wyller, T.B.4
  • 19
    • 84865627930 scopus 로고    scopus 로고
    • Prevalence of metabolic syndrome among adults 20 years of age and over by sex age race and ethnicity and body mass index: United States 2003-2006
    • Ervin RB: Prevalence of metabolic syndrome among adults 20 years of age and over, by sex, age, race and ethnicity, and body mass index: United States, 2003-2006. Natl Health Stat. Report 13, 1-7 (2009).
    • (2009) Natl Health Stat Report , vol.13 , pp. 1-7
    • Ervin, R.B.1
  • 20
    • 32144433666 scopus 로고    scopus 로고
    • Obesity has a greater impact on cardiovascular mortality in younger men than in older men among non-smoking Koreans
    • Park HS, Song YM, Cho SI: Obesity has a greater impact on cardiovascular mortality in younger men than in older men among non-smoking Koreans. Int. J. Epidemiol. 35, 181-187 (2006).
    • (2006) Int. J. Epidemiol. , vol.35 , pp. 181-187
    • Park, H.S.1    Song, Y.M.2    Cho, S.I.3
  • 21
    • 33749080537 scopus 로고    scopus 로고
    • The relations of body composition and adiposity measures to ill health and physical disability in elderly men
    • Ramsay SE, Whincup PH, Shaper AG, Wannamethee SG: The relations of body composition and adiposity measures to ill health and physical disability in elderly men. Am. J. Epidemiol. 164, 459-469 (2006).
    • (2006) Am. J. Epidemiol. , vol.164 , pp. 459-469
    • Ramsay, S.E.1    Whincup, P.H.2    Shaper, A.G.3    Wannamethee, S.G.4
  • 22
    • 66149189438 scopus 로고    scopus 로고
    • Factor analysis of the individual components of the metabolic syndrome among elderly identifies two factors with different survival patterns - A population-based study
    • Ohrvik J, Hedberg P, Jonason T, Lönnberg I, Nilsson G: Factor analysis of the individual components of the metabolic syndrome among elderly identifies two factors with different survival patterns - a population-based study. Metab. Syndr. Relat. Disord. 7, 171-177 (2009).
    • (2009) Metab. Syndr. Relat. Disord. , vol.7 , pp. 171-177
    • Ohrvik, J.1    Hedberg, P.2    Jonason, T.3    Lönnberg, I.4    Nilsson, G.5
  • 23
    • 0031851293 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus: Provisional report of a WHO consultation
    • Alberti KG, Zimmet PZ: Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus: provisional report of a WHO consultation. Diabet. Med. 15, 539-553 (1998).
    • (1998) Diabet. Med. , vol.15 , pp. 539-553
    • Alberti, K.G.1    Zimmet, P.Z.2
  • 24
    • 0032709705 scopus 로고    scopus 로고
    • Comment on the provisional report from the WHO consultation
    • European Group for the Study of Insulin Resistance (EGIR)
    • Balkau B, Charles MA: Comment on the provisional report from the WHO consultation. European Group for the Study of Insulin Resistance (EGIR). Diabet. Med. 16, 683-689 (1999).
    • (1999) Diabet. Med. , vol.16 , pp. 683-689
    • Balkau, B.1    Charles, M.A.2
  • 25
    • 0035897696 scopus 로고    scopus 로고
    • Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults: Executive summary of the third report of the national cholesterol education program (NCEP), expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults: Executive summary of the Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 285, 2486-2497 (2001).
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 26
    • 3242795814 scopus 로고    scopus 로고
    • Intra-abdominal fat is a major determinant of the national cholesterol education program adult treatment panel III criteria for the metabolic syndrome
    • Carr DB, Utzschneider KM, Hull RL et al.: Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome. Diabetes 53, 2087-2097 (2004).
    • (2004) Diabetes , vol.53 , pp. 2087-2097
    • Carr, D.B.1    Utzschneider, K.M.2    Hull, R.L.3
  • 27
    • 0042031497 scopus 로고    scopus 로고
    • American association of clinical endocrinologists (AACE) consensus conference on the insulin resistance syndrome: 25-26 August 2002 Washington DC
    • Bloomgarden ZT: American Association of Clinical Endocrinologists (AACE) consensus conference on the insulin resistance syndrome: 25-26 August 2002, Washington, DC. Diabetes Care 26, 933-939 (2003).
    • (2003) Diabetes Care , vol.26 , pp. 933-939
    • Bloomgarden, Z.T.1
  • 29
    • 66549130863 scopus 로고    scopus 로고
    • The emerging clinical implications of the role of aldosterone in the metabolic syndrome and resistant hypertension
    • Sowers JR, Whaley-Connell A, Epstein M: The emerging clinical implications of the role of aldosterone in the metabolic syndrome and resistant hypertension. Ann. Intern. Med. 150, 776-783 (2009).
    • (2009) Ann. Intern. Med. , vol.150 , pp. 776-783
    • Sowers, J.R.1    Whaley-Connell, A.2    Epstein, M.3
  • 30
    • 67149134992 scopus 로고    scopus 로고
    • Mechanisms of hypertension in the cardiometabolic syndrome
    • Redon J, Cifkova R, Laurent S et al.: Mechanisms of hypertension in the cardiometabolic syndrome. J. Hypertens. 27, 441-451 (2009).
    • (2009) J. Hypertens. , vol.27 , pp. 441-451
    • Redon, J.1    Cifkova, R.2    Laurent, S.3
  • 31
    • 34248228264 scopus 로고    scopus 로고
    • Mechanisms of the components of the metabolic syndrome that predispose to diabetes and atherosclerotic CVD
    • Eckel RH: Mechanisms of the components of the metabolic syndrome that predispose to diabetes and atherosclerotic CVD. Proc. Nutr. Soc. 66, 82-95 (2007).
    • (2007) Proc. Nutr. Soc. , vol.66 , pp. 82-95
    • Eckel, R.H.1
  • 32
    • 0842285784 scopus 로고    scopus 로고
    • American diabetes association: Clinical management of metabolic syndrome. Report of the American heart association/national heart lung and blood institute/American diabetes association conference on scientific issues related to management
    • American Heart Association; National Heart Lung, and Blood Institute
    • Grundy SM, Hansen B, Smith SC Jr, Cleeman JI, Kahn RA; American Heart Association; National Heart, Lung, and Blood Institute; American Diabetes Association: Clinical management of metabolic syndrome. Report of the American Heart Association/National Heart, Lung, and Blood Institute/American Diabetes Association Conference on Scientific Issues Related to Management. Circulation 109, 551-556 (2004).
    • (2004) Circulation , vol.109 , pp. 551-556
    • Grundy, S.M.1    Hansen, B.2    Smith Jr., S.C.3    Cleeman, J.I.4    Kahn, R.A.5
  • 33
    • 33748303084 scopus 로고    scopus 로고
    • Reduction of low-density lipoprotein cholesterol in patients with coronary heart disease and metabolic syndrome: Analysis of the treating to new targets study
    • Treating to New Targets Investigators
    • Deedwania P, Barter P, Carmena R et al.; Treating to New Targets Investigators: Reduction of low-density lipoprotein cholesterol in patients with coronary heart disease and metabolic syndrome: analysis of the Treating to New Targets study. Lancet 368, 919-928 (2006).
    • (2006) Lancet , vol.368 , pp. 919-928
    • Deedwania, P.1    Barter, P.2    Carmena, R.3
  • 34
    • 4544310589 scopus 로고    scopus 로고
    • Low birth weight in combination with catch-up growth predicts the occurrence of the metabolic syndrome in men in late middle age. The atherosclerosis and insulin resistance (AIR) study
    • Fagerberg B, Bondjers L, Nilsson PM: Low birth weight in combination with catch-up growth predicts the occurrence of the metabolic syndrome in men in late middle age. The Atherosclerosis and Insulin Resistance (AIR) study. J. Intern. Med. 256, 1-6 (2004).
    • (2004) J. Intern. Med. , vol.256 , pp. 1-6
    • Fagerberg, B.1    Bondjers, L.2    Nilsson, P.M.3
  • 35
    • 7444263395 scopus 로고    scopus 로고
    • Metabolic syndrome as a predictor of all-cause and cardiovascular mortality in Type 2 diabetes
    • The Casale Monferrato Study
    • Bruno G, Merletti F, Biggeri A et al.: Metabolic syndrome as a predictor of all-cause and cardiovascular mortality in Type 2 diabetes. The Casale Monferrato Study. Diabetes Care 27, 2689-2694 (2004).
    • (2004) Diabetes Care , vol.27 , pp. 2689-2694
    • Bruno, G.1    Merletti, F.2    Biggeri, A.3
  • 36
    • 2542503919 scopus 로고    scopus 로고
    • Using metabolic syndrome traits for efficient detection of impaired glucose tolerance
    • Meigs JB, Williams K, Sullivan LM et al.: Using metabolic syndrome traits for efficient detection of impaired glucose tolerance. Diabetes Care 27, 1417-1426 (2004).
    • (2004) Diabetes Care , vol.27 , pp. 1417-1426
    • Meigs, J.B.1    Williams, K.2    Sullivan, L.M.3
  • 37
    • 7444269499 scopus 로고    scopus 로고
    • Does the metabolic syndrome improve identification of individuals at risk of Type 2 diabetes and/or cardiovascular disease?
    • Stern MP, Williams K, Gonzales-Villalpando C, Hunt K, Haffner SM: Does the metabolic syndrome improve identification of individuals at risk of Type 2 diabetes and/or cardiovascular disease? Diabetes Care 27, 2676-2681 (2004).
    • (2004) Diabetes Care , vol.27 , pp. 2676-2681
    • Stern, M.P.1    Williams, K.2    Gonzales-Villalpando, C.3    Hunt, K.4    Haffner, S.M.5
  • 38
    • 0035847591 scopus 로고    scopus 로고
    • Glucose tolerance and cardiovascular mortality. Comparison of fasting and 2-hour diagnostic criteria
    • The DECODE Study Group; European Diabetes Epidemiology Group
    • The DECODE Study Group; European Diabetes Epidemiology Group: Glucose tolerance and cardiovascular mortality. Comparison of fasting and 2-hour diagnostic criteria. Arch. Intern. Med. 161, 397-404 (2001).
    • (2001) Arch. Intern. Med. , vol.161 , pp. 397-404
  • 40
    • 16244381893 scopus 로고    scopus 로고
    • The inflammatory syndrome: The role of adipose tissue cytokines in metabolic disorders linked to obesity
    • Wisse BE: The inflammatory syndrome: the role of adipose tissue cytokines in metabolic disorders linked to obesity. J. Am. Soc. Nephrol. 15, 2792-2800 (2004).
    • (2004) J. Am. Soc. Nephrol. , vol.15 , pp. 2792-2800
    • Wisse, B.E.1
  • 41
    • 35448999348 scopus 로고    scopus 로고
    • Adipocyte/macrophage fatty acid binding proteins in metabolic syndrome
    • Erbay E, Cao H, Hotamisligil GS: Adipocyte/macrophage fatty acid binding proteins in metabolic syndrome. Curr. Atheroscler. Rep. 9, 222-229 (2007).
    • (2007) Curr. Atheroscler. Rep. , vol.9 , pp. 222-229
    • Erbay, E.1    Cao, H.2    Hotamisligil, G.S.3
  • 43
    • 0842324779 scopus 로고    scopus 로고
    • Obesity wars: Molecular progress confronts an expanding epidemic
    • Flier JS: Obesity wars: molecular progress confronts an expanding epidemic. Cell 116, 337-350 (2004).
    • (2004) Cell , vol.116 , pp. 337-350
    • Flier, J.S.1
  • 44
    • 1542313876 scopus 로고    scopus 로고
    • Interleukin-6 induces oxidative stress and endothelial dysfunction by overexpression of the angiotensin II type 1 receptor
    • Wassmann S, Stumpf M, Strehlow K et al.: Interleukin-6 induces oxidative stress and endothelial dysfunction by overexpression of the angiotensin II type 1 receptor. Circ. Res. 94, 534-541 (2004).
    • (2004) Circ. Res. , vol.94 , pp. 534-541
    • Wassmann, S.1    Stumpf, M.2    Strehlow, K.3
  • 45
  • 46
    • 32044432093 scopus 로고    scopus 로고
    • Human genetics of adiponectin in the metabolic syndrome
    • Yang WS, Chuang LM: Human genetics of adiponectin in the metabolic syndrome. J. Mol. Med. 84, 112-121 (2006).
    • (2006) J. Mol. Med. , vol.84 , pp. 112-121
    • Yang, W.S.1    Chuang, L.M.2
  • 47
    • 50449083989 scopus 로고    scopus 로고
    • The metabolic syndrome as a concept of adipose tissue disease
    • Oda E: The metabolic syndrome as a concept of adipose tissue disease. Hypertens. Res. 31, 1283-1291 (2009).
    • (2009) Hypertens. Res. , vol.31 , pp. 1283-1291
    • Oda, E.1
  • 48
    • 0024026298 scopus 로고
    • Lilly lecture. The triumvirate: B-cell, muscle, liver. A collusion responsible for NIDDM
    • DeFronzo RA: Lilly lecture. The triumvirate: b-cell, muscle, liver. A collusion responsible for NIDDM. Diabetes 37, 667-687 (1988).
    • (1988) Diabetes , vol.37 , pp. 667-687
    • De Fronzo, R.A.1
  • 49
    • 12344305124 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and Type 2 diabetes
    • Lowell BB, Shulman GI: Mitochondrial dysfunction and Type 2 diabetes. Science 307, 384-387 (2005).
    • (2005) Science , vol.307 , pp. 384-387
    • Lowell, B.B.1    Shulman, G.I.2
  • 50
    • 9144271149 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor-d induces fatty acid b-oxidation in skeletal muscle and attenuates metabolic syndrome
    • Tanaka T, Yamamoto J, Iwasaki S et al.: Activation of peroxisome proliferator-activated receptor-d induces fatty acid b-oxidation in skeletal muscle and attenuates metabolic syndrome. Proc. Natl Acad. Sci. USA 100, 15924-15929 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 15924-15929
    • Tanaka, T.1    Yamamoto, J.2    Iwasaki, S.3
  • 51
    • 64649104158 scopus 로고    scopus 로고
    • Banting lecture. from the triumvirate to the ominous octet: A new paradigm for the treatment of Type 2 diabetes mellitus
    • Defronzo RA: Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of Type 2 diabetes mellitus. Diabetes 58, 773-795 (2009).
    • (2009) Diabetes , vol.58 , pp. 773-795
    • Defronzo, R.A.1
  • 52
    • 0141755328 scopus 로고    scopus 로고
    • A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop Type 2 diabetes
    • Kashyap S, Belfort R, Gastaldelli A et al.: A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop Type 2 diabetes. Diabetes 52, 2461-2474 (2003).
    • (2003) Diabetes , vol.52 , pp. 2461-2474
    • Kashyap, S.1    Belfort, R.2    Gastaldelli, A.3
  • 53
    • 1642377274 scopus 로고    scopus 로고
    • Impaired mitochondrial activity in the insulin-resistant offspring of patients with Type 2 diabetes
    • Petersen KF, Dufour S, Befroy D, Garcia R, Shulman GI: Impaired mitochondrial activity in the insulin-resistant offspring of patients with Type 2 diabetes. N. Engl. J. Med. 350, 664-671 (2004).
    • (2004) N. Engl. J. Med. , vol.350 , pp. 664-671
    • Petersen, K.F.1    Dufour, S.2    Befroy, D.3    Garcia, R.4    Shulman, G.I.5
  • 56
    • 0035897696 scopus 로고    scopus 로고
    • Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults: Executive summary of the third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults: Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA 285, 2486-2497 (2001).
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 59
    • 2542419937 scopus 로고    scopus 로고
    • Insulin resistance and hypertension: The insulin resistance atherosclerosis study
    • Saad MF, Rewers M, Selby J et al.: Insulin resistance and hypertension: the Insulin Resistance Atherosclerosis study. Hypertension 43, 1324-1331 (2004).
    • (2004) Hypertension , vol.43 , pp. 1324-1331
    • Saad, M.F.1    Rewers, M.2    Selby, J.3
  • 60
    • 0037446396 scopus 로고    scopus 로고
    • Are metabolic risk factors one unified syndrome? Modeling the structure of the metabolic syndrome X
    • Shen BJ, Todaro JF, Niaura R et al.: Are metabolic risk factors one unified syndrome? Modeling the structure of the metabolic syndrome X. Am. J. Epidemiol. 157, 701-711 (2003).
    • (2003) Am. J. Epidemiol. , vol.157 , pp. 701-711
    • Shen, B.J.1    Todaro, J.F.2    Niaura, R.3
  • 61
    • 36448973074 scopus 로고    scopus 로고
    • Pulse hypertension: A new component of the metabolic syndrome in elderly women?
    • Mazza A, Zamboni S, Tikhonoff V et al.: Pulse hypertension: a new component of the metabolic syndrome in elderly women? J. Hum. Hypert. 21, 934-941 (2007).
    • (2007) J. Hum. Hypert. , vol.21 , pp. 934-941
    • Mazza, A.1    Zamboni, S.2    Tikhonoff, V.3
  • 62
    • 0035211741 scopus 로고    scopus 로고
    • Pulse pressure: An independent predictor of coronary and stroke mortality in elderly females from the general population
    • Mazza A, Pessina AC, Tikhonoff V, Pavei A, Privato G, Casiglia E: Pulse pressure: an independent predictor of coronary and stroke mortality in elderly females from the general population. Blood Pressure 10, 205-211 (2001).
    • (2001) Blood Pressure , vol.10 , pp. 205-211
    • Mazza, A.1    Pessina, A.C.2    Tikhonoff, V.3    Pavei, A.4    Privato, G.5    Casiglia, E.6
  • 63
    • 0036746567 scopus 로고    scopus 로고
    • Pulse pressure and coronary mortality in elderly men and women from general population
    • Casiglia E, Tikhonoff V, Mazza A, Piccoli A, Pessina AC: Pulse pressure and coronary mortality in elderly men and women from general population. J. Hum. Hypert. 16: 611-620 (2002).
    • (2002) J. Hum. Hypert. , vol.16 , pp. 611-620
    • Casiglia, E.1    Tikhonoff, V.2    Mazza, A.3    Piccoli, A.4    Pessina, A.C.5
  • 64
    • 34548316470 scopus 로고    scopus 로고
    • Metabolic syndrome: Nothing more than a constellation?
    • Tikhonoff V, Casiglia E: Metabolic syndrome: nothing more than a constellation? Eur. Heart J. 28, 780-781 (2007).
    • (2007) Eur. Heart J. , vol.28 , pp. 780-781
    • Tikhonoff, V.1    Casiglia, E.2
  • 65
    • 24144438263 scopus 로고    scopus 로고
    • Increased mortality associated with the metabolic syndrome in older women with diabetes
    • Hillier TA, Rizzo JH, Pedula KL et al.: Increased mortality associated with the metabolic syndrome in older women with diabetes. Diabetes Care 28, 2258-2260 (2005).
    • (2005) Diabetes Care , vol.28 , pp. 2258-2260
    • Hillier, T.A.1    Rizzo, J.H.2    Pedula, K.L.3
  • 66
    • 73949122751 scopus 로고    scopus 로고
    • Blood pressure through aging and menopause
    • Taddei S: Blood pressure through aging and menopause. Climacteric 12(Suppl. 1), 36-40 (2009).
    • (2009) Climacteric , vol.12 , Issue.SUPPL. 1 , pp. 36-40
    • Taddei, S.1
  • 67
    • 33845765241 scopus 로고    scopus 로고
    • Body mass index and mortality in elderly men and women from general population. The experience of cardiovascular study in the elderly (CASTEL)
    • Mazza A, Zamboni S, Tikhonoff V, Pessina AC, Casiglia E: Body mass index and mortality in elderly men and women from general population. The experience of Cardiovascular Study in the Elderly (CASTEL). Gerontology 53, 36-45 (2007).
    • (2007) Gerontology , vol.53 , pp. 36-45
    • Mazza, A.1    Zamboni, S.2    Tikhonoff, V.3    Pessina, A.C.4    Casiglia, E.5
  • 68
    • 0031667011 scopus 로고    scopus 로고
    • Cardiovascular risk factors in the elderly
    • Casiglia E, Palatini P: Cardiovascular risk factors in the elderly. J. Hum. Hypert. 12, 575-581 (1998).
    • (1998) J. Hum. Hypert. , vol.12 , pp. 575-581
    • Casiglia, E.1    Palatini, P.2
  • 69
    • 0027716775 scopus 로고
    • Predictors of mortality in very old subjects aged 80 years or over. The CASTEL (Cardiovascular Study in the Elderly)
    • Casiglia E, Spolaore P, Ginocchio G et al.: Predictors of mortality in very old subjects aged 80 years or over. The CASTEL (Cardiovascular Study in the Elderly). Eur. J. Epidemiol. 9, 577-586 (1993).
    • (1993) Eur. J. Epidemiol. , vol.9 , pp. 577-586
    • Casiglia, E.1    Spolaore, P.2    Ginocchio, G.3
  • 72
    • 33645969319 scopus 로고    scopus 로고
    • Clinical value of the metabolic syndrome for long term prediction of total and cardiovascular mortality: Prospective, population based cohort study
    • Sundström J, Riserus U, Byberg L, Zethelius B, Lithell H, Lind L: Clinical value of the metabolic syndrome for long term prediction of total and cardiovascular mortality: prospective, population based cohort study. BMJ 332, 878-882 (2006).
    • (2006) BMJ , vol.332 , pp. 878-882
    • Sundström, J.1    Riserus, U.2    Byberg, L.3    Zethelius, B.4    Lithell, H.5    Lind, L.6
  • 73
    • 33746394704 scopus 로고    scopus 로고
    • Risk associated with the metabolic syndrome versus the sum of its individual components
    • Sundström J, Vallhagen E, Riserus U et al.: Risk associated with the metabolic syndrome versus the sum of its individual components. Diabetes Care 29, 1673-1674 (2006).
    • (2006) Diabetes Care , vol.29 , pp. 1673-1674
    • Sundström, J.1    Vallhagen, E.2    Riserus, U.3
  • 74
    • 33646054862 scopus 로고    scopus 로고
    • Metabolic syndrome and the risk of cardiovascular disease in older adults
    • Butler J, Rodondi N, Zhu Y et al.: Metabolic syndrome and the risk of cardiovascular disease in older adults. J. Am. Coll. Cardiol. 47, 1595-1602 (2006).
    • (2006) J. Am. Coll. Cardiol. , vol.47 , pp. 1595-1602
    • Butler, J.1    Rodondi, N.2    Zhu, Y.3
  • 75
    • 33646948869 scopus 로고    scopus 로고
    • Metabolic syndrome, diabetes, and cardiovascular disease in an elderly Caucasian cohort: The Italian longitudinal study on aging
    • Maggi S, Noale M, Gallina P et al.: Metabolic syndrome, diabetes, and cardiovascular disease in an elderly Caucasian cohort: the Italian Longitudinal Study on Aging. J. Gerontol. A Biol. Sci. Med. Sci. 61, 505-510 (2006).
    • (2006) J. Gerontol. A Biol. Sci. Med. Sci. , vol.61 , pp. 505-510
    • Maggi, S.1    Noale, M.2    Gallina, P.3
  • 76
    • 63149182149 scopus 로고    scopus 로고
    • The metabolic syndrome in the elderly: Considerations on the diagnostic criteria of the international diabetes federation and some proposed modifications
    • Motta M, Bennati E, Cardillo E, Passamonte M, Ferlito L, Malaguarnera M: The metabolic syndrome in the elderly: considerations on the diagnostic criteria of the International Diabetes Federation and some proposed modifications. Arch. Gerontol. Geriatr. 48, 380-384 (2009).
    • (2009) Arch. Gerontol. Geriatr. , vol.48 , pp. 380-384
    • Motta, M.1    Bennati, E.2    Cardillo, E.3    Passamonte, M.4    Ferlito, L.5    Malaguarnera, M.6
  • 77
    • 15944411404 scopus 로고    scopus 로고
    • The metabolic syndrome in older individuals: Prevalence and prediction of cardiovascular events: The cardiovascular health study
    • Scuteri A, Najjar SS, Morrell CH, Lakatta EG: The metabolic syndrome in older individuals: prevalence and prediction of cardiovascular events: the Cardiovascular Health Study. Diabetes Care 28, 882-887 (2005).
    • (2005) Diabetes Care , vol.28 , pp. 882-887
    • Scuteri, A.1    Najjar, S.S.2    Morrell, C.H.3    Lakatta, E.G.4
  • 78
    • 33748429140 scopus 로고    scopus 로고
    • Metabolic syndrome and cardiovascular disease in older people: The cardiovascular health study
    • McNeill AM, Katz R, Girman CJ et al.: Metabolic syndrome and cardiovascular disease in older people: the Cardiovascular Health Study. J. Am. Geriatr. Soc. 54, 1317-1324 (2006).
    • (2006) J. Am. Geriatr. Soc. , vol.54 , pp. 1317-1324
    • Mc Neill, A.M.1    Katz, R.2    Girman, C.J.3
  • 79
    • 34247479984 scopus 로고    scopus 로고
    • Obesity, disability, and mortality: Puzzling link
    • Ferrucci L, Alley D: Obesity, disability, and mortality: puzzling link. Arch. Intern. Med. 167, 750-751 (2007).
    • (2007) Arch. Intern. Med. , vol.167 , pp. 750-751
    • Ferrucci, L.1    Alley, D.2
  • 80
    • 0142125286 scopus 로고    scopus 로고
    • Obesity in 70-year-old subjects as a risk factor for 15-year coronary heart disease incidence
    • Dey DK, Lissner L: Obesity in 70-year-old subjects as a risk factor for 15-year coronary heart disease incidence. Obes. Res.11, 817-827 (2003).
    • (2003) Obes. Res. , vol.11 , pp. 817-827
    • Dey, D.K.1    Lissner, L.2
  • 81
    • 3242662149 scopus 로고    scopus 로고
    • C-reactive protein, the metabolic syndrome, and prediction of cardiovascular events in the Framingham offspring study
    • Rutter MK, Meigs JB, Sullivan LM, D'Agostino RB Sr, Wilson PW: C-reactive protein, the metabolic syndrome, and prediction of cardiovascular events in the Framingham Offspring Study. Circulation 110, 380-385 (2004).
    • (2004) Circulation , vol.110 , pp. 380-385
    • Rutter, M.K.1    Meigs, J.B.2    Sullivan, L.M.3    D'agostino Sr., R.B.4    Wilson, P.W.5
  • 82
    • 12844262139 scopus 로고    scopus 로고
    • The metabolic syndrome and 11-year risk of incident cardiovascular disease in the atherosclerosis risk in communities study
    • McNeill AM, Rosamond WD, Girman CJ et al.: The metabolic syndrome and 11-year risk of incident cardiovascular disease in the atherosclerosis risk in communities study. Diabetes Care 28, 385-390 (2005).
    • (2005) Diabetes Care , vol.28 , pp. 385-390
    • Mc Neill, A.M.1    Rosamond, W.D.2    Girman, C.J.3
  • 83
    • 4444222221 scopus 로고    scopus 로고
    • Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults
    • Malik S, Wong ND, Franklin SS et al.: Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults. Circulation 110, 1245-1250 (2004).
    • (2004) Circulation , vol.110 , pp. 1245-1250
    • Malik, S.1    Wong, N.D.2    Franklin, S.S.3
  • 84
    • 4444329030 scopus 로고    scopus 로고
    • National cholesterol education program versus world health organization metabolic syndrome in relation to all-cause and cardiovascular mortality in the San Antonio Heart Study
    • Hunt KJ, Resendez RG, Williams K, Haffner SM, Stern MP: National Cholesterol Education Program versus World Health Organization metabolic syndrome in relation to all-cause and cardiovascular mortality in the San Antonio Heart Study. Circulation 110, 1251-1257 (2004).
    • (2004) Circulation , vol.110 , pp. 1251-1257
    • Hunt, K.J.1    Resendez, R.G.2    Williams, K.3    Haffner, S.M.4    Stern, M.P.5
  • 85
    • 34548329794 scopus 로고    scopus 로고
    • The metabolic syndrome predicts cardiovascular mortality: A 13-year follow-up study in elderly non-diabetic Finns
    • Wang J, Ruotsalainen S, Moilanen L, Depisto PI, Laakso M, Kuusisto J: The metabolic syndrome predicts cardiovascular mortality: a 13-year follow-up study in elderly non-diabetic Finns. Eur. Heart J. 28, 857-864 (2007).
    • (2007) Eur. Heart J. , vol.28 , pp. 857-864
    • Wang, J.1    Ruotsalainen, S.2    Moilanen, L.3    Depisto, P.I.4    Laakso, M.5    Kuusisto, J.6
  • 86
    • 67650445630 scopus 로고    scopus 로고
    • Cardiac health in women with metabolic syndrome: Clinical aspects and pathophysiology
    • Ren J, Kelley RO: Cardiac health in women with metabolic syndrome: clinical aspects and pathophysiology. Obesity 17, 1114-1123 (2009).
    • (2009) Obesity , vol.17 , pp. 1114-1123
    • Ren, J.1    Kelley, R.O.2
  • 87
    • 64549157687 scopus 로고    scopus 로고
    • Metabolic syndrome and all-cause and cardiovascular mortality in an Italian elderly population: The Progetto Veneto Anziani (Pro.V.A.) study
    • Zambon S, Zanoni S, Romanato G et al.: Metabolic syndrome and all-cause and cardiovascular mortality in an Italian elderly population: the Progetto Veneto Anziani (Pro.V.A.) study. Diabetes Care 32, 153-159 (2009).
    • (2009) Diabetes Care , vol.32 , pp. 153-159
    • Zambon, S.1    Zanoni, S.2    Romanato, G.3
  • 88
    • 33845474558 scopus 로고    scopus 로고
    • Metabolic syndrome: Prevalence and prediction of mortality in elderly individuals
    • Ravaglia G, Forti P, Maioli F et al.: Metabolic syndrome: prevalence and prediction of mortality in elderly individuals. Diabetes Care 29, 2471-2476 (2006).
    • (2006) Diabetes Care , vol.29 , pp. 2471-2476
    • Ravaglia, G.1    Forti, P.2    Maioli, F.3
  • 89
    • 33847629191 scopus 로고    scopus 로고
    • Metabolic syndrome and early death: Getting to the heart of the problem
    • Franks PW, Olsson T: Metabolic syndrome and early death: getting to the heart of the problem. Hypertension 49, 10-12 (2007).
    • (2007) Hypertension , vol.49 , pp. 10-12
    • Franks, P.W.1    Olsson, T.2
  • 90
    • 43549083053 scopus 로고    scopus 로고
    • Metabolic syndrome and mortality in older adults. The cardiovascular health study
    • Mozaffarian D, Kamineni A, Prineas RJ, Siscovick DS: Metabolic syndrome and mortality in older adults. The Cardiovascular Health Study. Arch. Intern. Med. 168, 969-978 (2008).
    • (2008) Arch. Intern. Med. , vol.168 , pp. 969-978
    • Mozaffarian, D.1    Kamineni, A.2    Prineas, R.J.3    Siscovick, D.S.4
  • 91
    • 34548057004 scopus 로고    scopus 로고
    • Management of cardiovascular risk in patients with Type 2 diabetes mellitus as a component of the cardiometabolic syndrome
    • Ferdinand KC: Management of cardiovascular risk in patients with Type 2 diabetes mellitus as a component of the cardiometabolic syndrome. J. Cardiometab. Syndr. 1, 133-140 (2006).
    • (2006) J. Cardiometab. Syndr. , vol.1 , pp. 133-140
    • Ferdinand, K.C.1
  • 92
    • 17144389303 scopus 로고    scopus 로고
    • The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: The diabetes prevention program randomized trial
    • Diabetes Prevention Program Research Group
    • Orchard TJ, Temprosa M, Goldberg R et al.; Diabetes Prevention Program Research Group: The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial. Ann. Intern. Med. 142, 611-619 (2005).
    • (2005) Ann. Intern. Med. , vol.142 , pp. 611-619
    • Orchard, T.J.1    Temprosa, M.2    Goldberg, R.3
  • 93
    • 33646353949 scopus 로고    scopus 로고
    • Emerging therapies mimicking the effects of amylin and glucagon-like peptide-1
    • Riddle MC, Drucker DJ: Emerging therapies mimicking the effects of amylin and glucagon-like peptide-1. Diabetes Care 29, 435-439 (2006).
    • (2006) Diabetes Care , vol.29 , pp. 435-439
    • Riddle, M.C.1    Drucker, D.J.2
  • 94
    • 1542509875 scopus 로고    scopus 로고
    • Should the insulin resistance syndrome be treated in the elderly?
    • Grant RW, Meigs JB: Should the insulin resistance syndrome be treated in the elderly? Drugs Aging 21, 141-151 (2004).
    • (2004) Drugs Aging , vol.21 , pp. 141-151
    • Grant, R.W.1    Meigs, J.B.2
  • 95
    • 0042707908 scopus 로고    scopus 로고
    • Sedentary lifestyle, poor cardiorespiratory fitness, and the metabolic syndrome
    • Lakka TA, Laaksonen DE, Lakka HM et al.: Sedentary lifestyle, poor cardiorespiratory fitness, and the metabolic syndrome. Med. Sci. Sports Exerc. 35, 1279-1286 (2003).
    • (2003) Med. Sci. Sports Exerc. , vol.35 , pp. 1279-1286
    • Lakka, T.A.1    Laaksonen, D.E.2    Lakka, H.M.3
  • 96
    • 48649100081 scopus 로고    scopus 로고
    • Cardiorespiratory fitness as a feature of metabolic syndrome in older men and women: The dose-responses to exercise training study
    • Hassinen M, Lakka TA, Savonen K et al.: Cardiorespiratory fitness as a feature of metabolic syndrome in older men and women: the Dose-Responses to Exercise Training study. Diabetes Care 31, 1242-1247 (2008).
    • (2008) Diabetes Care , vol.31 , pp. 1242-1247
    • Hassinen, M.1    Lakka, T.A.2    Savonen, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.