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Volumn 31, Issue 7, 2008, Pages 1283-1291

The metabolic syndrome as a concept of adipose tissue disease

Author keywords

Cardiovascular disease; Diabetes; Inflammation; Metabolic syndrome; Obesity

Indexed keywords

C REACTIVE PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 50449083989     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1291/hypres.31.1283     Document Type: Review
Times cited : (96)

References (103)
  • 1
    • 0024160877 scopus 로고
    • Role of insulin resistance in human disease
    • Reaven GM: Role of insulin resistance in human disease. Diabetes 1988; 37: 1595-1607.
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 2
    • 0026021161 scopus 로고
    • Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease
    • DeFronzo RA, Ferrannini E: Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 1991; 14: 173-194.
    • (1991) Diabetes Care , vol.14 , pp. 173-194
    • DeFronzo, R.A.1    Ferrannini, E.2
  • 3
    • 0024391834 scopus 로고
    • The deadly quartet: Upper body obesity, glucose intolerance, hypertriglyceridemia and hypertension
    • Kaplan NM: The deadly quartet: upper body obesity, glucose intolerance, hypertriglyceridemia and hypertension. Arch Intern Med 1989; 149: 1514-1520.
    • (1989) Arch Intern Med , vol.149 , pp. 1514-1520
    • Kaplan, N.M.1
  • 4
    • 0034636818 scopus 로고    scopus 로고
    • Hypertriglyceridemic waist: A marker of the atherogenic metabolic triad (hyperinsulinemia; hyperapolipoprotein B; small, dense LDL) in men?
    • Lemieux I, Pascot A, Couillard C, et al: Hypertriglyceridemic waist: a marker of the atherogenic metabolic triad (hyperinsulinemia; hyperapolipoprotein B; small, dense LDL) in men? Circulation 2000; 102: 179-184.
    • (2000) Circulation , vol.102 , pp. 179-184
    • Lemieux, I.1    Pascot, A.2    Couillard, C.3
  • 5
    • 2942670689 scopus 로고    scopus 로고
    • Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk?
    • Ridker PM, Wilson PW, Grundy SM: Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk? Circulation 2004; 109: 2818-2825.
    • (2004) Circulation , vol.109 , pp. 2818-2825
    • Ridker, P.M.1    Wilson, P.W.2    Grundy, S.M.3
  • 6
    • 15444366991 scopus 로고    scopus 로고
    • Metabolic syndrome: A comprehensive perspective based on interactions between obesity, diabetes, and inflammation
    • Dandona P, Aljada A, Chaudhuri A, Mohanty P, Garg R: Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation. Circulation 2005; 111: 1448-1454.
    • (2005) Circulation , vol.111 , pp. 1448-1454
    • Dandona, P.1    Aljada, A.2    Chaudhuri, A.3    Mohanty, P.4    Garg, R.5
  • 7
    • 33645007540 scopus 로고    scopus 로고
    • Intake of fish and n-3 fatty acids and risk of coronary heart disease among Japanese: The Japan Public Health Center-based (JPHC) Study Cohort 1
    • Iso H, Kobayashi M, Ishihara J, et al: Intake of fish and n-3 fatty acids and risk of coronary heart disease among Japanese: the Japan Public Health Center-based (JPHC) Study Cohort 1. Circulation 2006; 113: 195-202.
    • (2006) Circulation , vol.113 , pp. 195-202
    • Iso, H.1    Kobayashi, M.2    Ishihara, J.3
  • 8
    • 36049006161 scopus 로고    scopus 로고
    • Dietary cod protein improves insulin sensitivity in insulin-resistant men and women
    • Ouellet V, Marois J, Weisnagel SJ, Jacques H: Dietary cod protein improves insulin sensitivity in insulin-resistant men and women. Diabetes Care 2007; 30: 2816-2821.
    • (2007) Diabetes Care , vol.30 , pp. 2816-2821
    • Ouellet, V.1    Marois, J.2    Weisnagel, S.J.3    Jacques, H.4
  • 9
    • 36048996277 scopus 로고    scopus 로고
    • Long-term predictors of insuli resistance. Role of lifestyle and metabolic factors in middle-aged men
    • Riserus U, Arnlov J, Berglund L: Long-term predictors of insuli resistance. Role of lifestyle and metabolic factors in middle-aged men. Diabetes Care 2007; 30: 2928-2933.
    • (2007) Diabetes Care , vol.30 , pp. 2928-2933
    • Riserus, U.1    Arnlov, J.2    Berglund, L.3
  • 10
    • 23044434517 scopus 로고    scopus 로고
    • Association between cigarette smoking and metabolic syndrome: The Korea National Health and Nutrition Examination Survey
    • Oh SW, Yoon YS, Lee ES, et al: Association between cigarette smoking and metabolic syndrome: the Korea National Health and Nutrition Examination Survey. Diabetes Care 2005; 28: 2064-2066.
    • (2005) Diabetes Care , vol.28 , pp. 2064-2066
    • Oh, S.W.1    Yoon, Y.S.2    Lee, E.S.3
  • 11
    • 0036819073 scopus 로고    scopus 로고
    • Relation of self-rated measures of physical activity to multiple risk factors of insulin resistance syndrome in young adults: The Bogalusa Heart Study
    • Gustat J, Srinivasan SR, Elkasabany A, Berenson GS: Relation of self-rated measures of physical activity to multiple risk factors of insulin resistance syndrome in young adults: the Bogalusa Heart Study. J Clin Epidemiol 2002; 55: 997-1006.
    • (2002) J Clin Epidemiol , vol.55 , pp. 997-1006
    • Gustat, J.1    Srinivasan, S.R.2    Elkasabany, A.3    Berenson, G.S.4
  • 12
    • 0037116641 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome among US adults: Findings from the Third National Health and Nutrition Examination Survey
    • Ford ES, Giles WH, Dietz WH: Prevalence of the metabolic syndrome among US adults: findings from the Third National Health and Nutrition Examination Survey. JAMA 2002; 287: 356-359.
    • (2002) JAMA , vol.287 , pp. 356-359
    • Ford, E.S.1    Giles, W.H.2    Dietz, W.H.3
  • 13
    • 17844367331 scopus 로고    scopus 로고
    • Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome
    • Apridonidze T, Essah PA, Iuorno MJ, Nestler JE: Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome. J Clin Endocrinol Metab 2004; 90: 1929-1935.
    • (2004) J Clin Endocrinol Metab , vol.90 , pp. 1929-1935
    • Apridonidze, T.1    Essah, P.A.2    Iuorno, M.J.3    Nestler, J.E.4
  • 14
    • 33847653870 scopus 로고    scopus 로고
    • Association between serum concentrations of persistent organic pollutants and insulin resistance among nondiabetic adults: Results from the National Health and Nutrition Examination Survey 1999-2002
    • Lee D, Lee I, Jin S, Steffes M, Jacobs DR Jr: Association between serum concentrations of persistent organic pollutants and insulin resistance among nondiabetic adults: results from the National Health and Nutrition Examination Survey 1999-2002. Diabetes Care 2007; 30: 622-628.
    • (2007) Diabetes Care , vol.30 , pp. 622-628
    • Lee, D.1    Lee, I.2    Jin, S.3    Steffes, M.4    Jacobs Jr, D.R.5
  • 15
  • 16
    • 0028363169 scopus 로고
    • Contribution of visceral fat accumulation to the development of coronary artery disease in non-obese men
    • Nakamura T, Tokunaga K, Shimomura I, et al: Contribution of visceral fat accumulation to the development of coronary artery disease in non-obese men. Atherosclerosis 1994; 107: 239-246.
    • (1994) Atherosclerosis , vol.107 , pp. 239-246
    • Nakamura, T.1    Tokunaga, K.2    Shimomura, I.3
  • 17
    • 0032562946 scopus 로고    scopus 로고
    • Fasting insulin and apolipoprotein B levels and low-density lipoprotein particle size as risk factors for ischemic heart disease
    • Lamarche B, Tchernof A, Mauriege P, et al: Fasting insulin and apolipoprotein B levels and low-density lipoprotein particle size as risk factors for ischemic heart disease. JAMA 1998; 279: 1955-1961.
    • (1998) JAMA , vol.279 , pp. 1955-1961
    • Lamarche, B.1    Tchernof, A.2    Mauriege, P.3
  • 18
    • 0003725206 scopus 로고    scopus 로고
    • Definition, Diagnosis, and Classification of Diabetes Mellitus and Its Complications
    • World Health Organization:, Geneva, World Health Organization
    • World Health Organization: Definition, Diagnosis, and Classification of Diabetes Mellitus and Its Complications: Report of a WHO Consultation. Geneva, World Health Organization, 1999.
    • (1999) Report of a WHO Consultation
  • 19
    • 0032709705 scopus 로고    scopus 로고
    • Comment on the provisional report from the WHO consultation. European Group for the Study of Insulin Resistance (EGIR)
    • Balkau B, Charles MA: Comment on the provisional report from the WHO consultation. European Group for the Study of Insulin Resistance (EGIR). Diabetes Med 1999; 16: 442-443.
    • (1999) Diabetes Med , vol.16 , pp. 442-443
    • Balkau, B.1    Charles, M.A.2
  • 20
    • 0035897696 scopus 로고    scopus 로고
    • Evaluation, and Treatment of High Blood Cholesterol in Adults: Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Expert Panel on the Detection
    • Expert Panel on the Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults: Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001; 285: 2486-2497.
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 21
    • 0347853481 scopus 로고    scopus 로고
    • American College of Endocrinology position statement on the insulin resistance syndrome
    • Einhorn D, Reaven GM, Cobin RH, et al: American College of Endocrinology position statement on the insulin resistance syndrome. Endocr Pract 2003; 9: 237-252.
    • (2003) Endocr Pract , vol.9 , pp. 237-252
    • Einhorn, D.1    Reaven, G.M.2    Cobin, R.H.3
  • 22
    • 33645978121 scopus 로고    scopus 로고
    • Metabolic syndrome - a new world-wide definition. A consensus statement from the International Diabetes Federation
    • Alverti KGMM, Zimmet P, Shaw J: Metabolic syndrome - a new world-wide definition. A consensus statement from the International Diabetes Federation. Diabet Med 2006; 23: 469-480.
    • (2006) Diabet Med , vol.23 , pp. 469-480
    • Alverti, K.G.M.M.1    Zimmet, P.2    Shaw, J.3
  • 23
    • 27444443876 scopus 로고    scopus 로고
    • Diagnosis and management of the metabolic syndrome: A statement for health care professionals: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
    • Grundy SM, Cleeman JI, Daniels SR, et al: Diagnosis and management of the metabolic syndrome: a statement for health care professionals: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005; 112: 2735-2752.
    • (2005) Circulation , vol.112 , pp. 2735-2752
    • Grundy, S.M.1    Cleeman, J.I.2    Daniels, S.R.3
  • 24
    • 24144484876 scopus 로고    scopus 로고
    • The metabolic syndrome: Time for a critical appraisal: joint statement from the American Diabetes Association and the European Association for the Study of Diabetes
    • Kahn R, Buse J, Ferrannini E, Stern M: The metabolic syndrome: time for a critical appraisal: joint statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2005; 28: 2289-2304.
    • (2005) Diabetes Care , vol.28 , pp. 2289-2304
    • Kahn, R.1    Buse, J.2    Ferrannini, E.3    Stern, M.4
  • 25
    • 33746429613 scopus 로고    scopus 로고
    • Does the metabolic syndrome exist?
    • Grundy SM: Does the metabolic syndrome exist? Diabetes Care 2006; 29: 1689-1692.
    • (2006) Diabetes Care , vol.29 , pp. 1689-1692
    • Grundy, S.M.1
  • 26
    • 33746453341 scopus 로고    scopus 로고
    • The metabolic syndrome (emperor) wears no clothes
    • Kahn R: The metabolic syndrome (emperor) wears no clothes. Diabetes Care 2006; 29: 1693-1696.
    • (2006) Diabetes Care , vol.29 , pp. 1693-1696
    • Kahn, R.1
  • 27
    • 33745603792 scopus 로고    scopus 로고
    • The metabolic syndrome: Is this diagnosis necessary?
    • Reaven GM: The metabolic syndrome: is this diagnosis necessary? Am J Clin Nutr 2006; 83: 1237-1247.
    • (2006) Am J Clin Nutr , vol.83 , pp. 1237-1247
    • Reaven, G.M.1
  • 28
    • 33745592823 scopus 로고    scopus 로고
    • Does a diagnosis of metabolic syndrome have value in clinical practice
    • Grundy SM: Does a diagnosis of metabolic syndrome have value in clinical practice. Am J Clin Nutr 2006; 83: 1248-1251.
    • (2006) Am J Clin Nutr , vol.83 , pp. 1248-1251
    • Grundy, S.M.1
  • 29
    • 33846944329 scopus 로고    scopus 로고
    • Metabolic syndrome: A solution in search of a problem
    • Ferrannini E: Metabolic syndrome: a solution in search of a problem. J Clin Endocrinol Metab 2007; 92: 396-398.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 396-398
    • Ferrannini, E.1
  • 30
    • 33846970555 scopus 로고    scopus 로고
    • Metabolic syndrome: A multiplex cardiovascular risk factor
    • Grundy SM: Metabolic syndrome: a multiplex cardiovascular risk factor. J Clin Endocrinol Metab 2007; 92: 399-404.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 399-404
    • Grundy, S.M.1
  • 31
    • 34247193564 scopus 로고    scopus 로고
    • Metabolic syndrome. Is it a syndrome? Does it matter
    • Kahn R: Metabolic syndrome. Is it a syndrome? Does it matter. Circulation 2007; 115: 1806-1811.
    • (2007) Circulation , vol.115 , pp. 1806-1811
    • Kahn, R.1
  • 32
    • 34247255415 scopus 로고    scopus 로고
    • Metabolic syndrome. A work in progress, but a useful construct
    • Beaser RS, Levy P: Metabolic syndrome. A work in progress, but a useful construct. Circulation 2007; 115: 1812-1818.
    • (2007) Circulation , vol.115 , pp. 1812-1818
    • Beaser, R.S.1    Levy, P.2
  • 33
    • 33746394704 scopus 로고    scopus 로고
    • Risk associated with the metabolic syndrome versus the sum of its individual components
    • Sundstrom J, Vallhagen E, Riserus U, et al: Risk associated with the metabolic syndrome versus the sum of its individual components. Diabetes Care 2006; 29: 1673-1674.
    • (2006) Diabetes Care , vol.29 , pp. 1673-1674
    • Sundstrom, J.1    Vallhagen, E.2    Riserus, U.3
  • 34
    • 33747114039 scopus 로고    scopus 로고
    • Preventing cardiovascular disease and diabetes: A call to action from the American Diabetes Association and the American Heart Association
    • Eckel RH, Kahn R, Robertson RM, Rizza RA: Preventing cardiovascular disease and diabetes: a call to action from the American Diabetes Association and the American Heart Association. Circulation 2006; 113: 2943-2946.
    • (2006) Circulation , vol.113 , pp. 2943-2946
    • Eckel, R.H.1    Kahn, R.2    Robertson, R.M.3    Rizza, R.A.4
  • 35
    • 4444222221 scopus 로고    scopus 로고
    • Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults
    • Malik S, Wong ND, Franklin SS, et al: Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults. Circulation 2004; 110: 1245-1250.
    • (2004) Circulation , vol.110 , pp. 1245-1250
    • Malik, S.1    Wong, N.D.2    Franklin, S.S.3
  • 36
    • 12844262139 scopus 로고    scopus 로고
    • The metabolic syndrome and 11-year risk of incident cardiovascular disease in the Atherosclerosis Risk in Communities Study
    • McNeil AM, Rosamond WD, Girman CJ, et al: The metabolic syndrome and 11-year risk of incident cardiovascular disease in the Atherosclerosis Risk in Communities Study. Diabetes Care 2005; 28: 385-390.
    • (2005) Diabetes Care , vol.28 , pp. 385-390
    • McNeil, A.M.1    Rosamond, W.D.2    Girman, C.J.3
  • 37
    • 21544462572 scopus 로고    scopus 로고
    • Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome
    • Ford ES: Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome. Diabetes Care 2005; 28: 1769-1778.
    • (2005) Diabetes Care , vol.28 , pp. 1769-1778
    • Ford, E.S.1
  • 38
    • 30944451953 scopus 로고    scopus 로고
    • Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus
    • Wilson PWF, D'Agostino RB, Parise H, Sullivan L, Meigs JB: Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus. Circulation 2005; 112: 3066-3072.
    • (2005) Circulation , vol.112 , pp. 3066-3072
    • Wilson, P.W.F.1    D'Agostino, R.B.2    Parise, H.3    Sullivan, L.4    Meigs, J.B.5
  • 39
    • 33750898257 scopus 로고    scopus 로고
    • Comparison of different definitions of the metabolic syndrome in relation to cardiovascular mortality in European men and women
    • The DECODE Study Group
    • The DECODE Study Group, Qiao Q: Comparison of different definitions of the metabolic syndrome in relation to cardiovascular mortality in European men and women. Diabetologia 2006; 49: 2837-2846.
    • (2006) Diabetologia , vol.49 , pp. 2837-2846
    • Qiao, Q.1
  • 40
    • 33846365989 scopus 로고    scopus 로고
    • Metabolic syndrome and risk of incident cardiovascular events and death
    • Gami AS, Witt BJ, Howard DE, et al: Metabolic syndrome and risk of incident cardiovascular events and death. J Am Coll Cardiol 2007; 49: 403-414.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 403-414
    • Gami, A.S.1    Witt, B.J.2    Howard, D.E.3
  • 41
    • 34347364688 scopus 로고    scopus 로고
    • Impact of metabolic syndrome on the development of cardiovascular disease in a general Japanese population. The Hisayama Study
    • Ninomiya T, Kubo M, Doi Y, et al: Impact of metabolic syndrome on the development of cardiovascular disease in a general Japanese population. The Hisayama Study. Stroke 2007; 38: 2063-2069.
    • (2007) Stroke , vol.38 , pp. 2063-2069
    • Ninomiya, T.1    Kubo, M.2    Doi, Y.3
  • 42
    • 33644876506 scopus 로고    scopus 로고
    • The new worldwide definition of metabolic syndrome is not a better diagnostic predictor of cardiovascular disease in Japanese diabetic patients than the existing definitions
    • Sone H, Tanaka S, Ishibashi S, et al: The new worldwide definition of metabolic syndrome is not a better diagnostic predictor of cardiovascular disease in Japanese diabetic patients than the existing definitions. Diabetes Care 2006; 29:145-147.
    • (2006) Diabetes Care , vol.29 , pp. 145-147
    • Sone, H.1    Tanaka, S.2    Ishibashi, S.3
  • 43
    • 33646364827 scopus 로고    scopus 로고
    • The importance of waist circumference in the definition of metabolic syndrome. Prospective analyses of mortality in men
    • Katzmarzyk PT, Janssen I, Ross R, Church TS, Blair SN: The importance of waist circumference in the definition of metabolic syndrome. Prospective analyses of mortality in men. Diabetes Care 2006; 29: 404-409.
    • (2006) Diabetes Care , vol.29 , pp. 404-409
    • Katzmarzyk, P.T.1    Janssen, I.2    Ross, R.3    Church, T.S.4    Blair, S.N.5
  • 44
    • 34250650005 scopus 로고    scopus 로고
    • Probable blind spot in the International Diabetes Federation definition of metabolic syndrome
    • Chen H, Pan W: Probable blind spot in the International Diabetes Federation definition of metabolic syndrome. Obesity 2007; 15: 1096-1100.
    • (2007) Obesity , vol.15 , pp. 1096-1100
    • Chen, H.1    Pan, W.2
  • 45
    • 33847296201 scopus 로고    scopus 로고
    • The new definition of metabolic syndrome by the International Diabetes Federation is less likely to identify metabolically abnormal but non-obese individuals than the definition by the revised National Cholesterol Education Program: The Korea NHANES Study
    • Yoon YS, Lee ES, Park C, Lee S, Oh SW: The new definition of metabolic syndrome by the International Diabetes Federation is less likely to identify metabolically abnormal but non-obese individuals than the definition by the revised National Cholesterol Education Program: the Korea NHANES Study. IntJ Obes 2007; 31: 528-534.
    • (2007) IntJ Obes , vol.31 , pp. 528-534
    • Yoon, Y.S.1    Lee, E.S.2    Park, C.3    Lee, S.4    Oh, S.W.5
  • 46
    • 34247578634 scopus 로고    scopus 로고
    • The usefulness of the International Diabetes Federation and the National Cholesterol Education Program's Adult Treatment Panel III definitions of the metabolic syndrome in predicting coronary heart disease in subjects with type 2 diabetes
    • Tong PC, Kong AP, So W, et al: The usefulness of the International Diabetes Federation and the National Cholesterol Education Program's Adult Treatment Panel III definitions of the metabolic syndrome in predicting coronary heart disease in subjects with type 2 diabetes. Diabetes Care 2007; 30: 1206-1211.
    • (2007) Diabetes Care , vol.30 , pp. 1206-1211
    • Tong, P.C.1    Kong, A.P.2    So, W.3
  • 47
    • 34547656232 scopus 로고    scopus 로고
    • A comparison of components of two definitions of the metabolic syndrome related to cardiovascular disease and all-cause mortality in a cohort study in Thailand
    • Tanomsup S, Aekplakorn W, Sritara P, et al: A comparison of components of two definitions of the metabolic syndrome related to cardiovascular disease and all-cause mortality in a cohort study in Thailand. Diabetes Care 2007; 30: 2138-2140.
    • (2007) Diabetes Care , vol.30 , pp. 2138-2140
    • Tanomsup, S.1    Aekplakorn, W.2    Sritara, P.3
  • 48
    • 34547676617 scopus 로고    scopus 로고
    • Is waist circumference an essential component of the metabolic syndrome?
    • Lorenzo C, Serrano-Rios M, Maritinez-Larrad MT, et al: Is waist circumference an essential component of the metabolic syndrome? Diabetes Care 2007; 30: 2141-2142.
    • (2007) Diabetes Care , vol.30 , pp. 2141-2142
    • Lorenzo, C.1    Serrano-Rios, M.2    Maritinez-Larrad, M.T.3
  • 49
    • 34249883032 scopus 로고    scopus 로고
    • Waist circumference and cardiometabolic risk: A consensus statement from Shaping America's Health: Association for Weight Management and Obesity Prevention; NAASO, the Obesity Society; the American Society for Nutrition; and the American Diabetes Association
    • Klein S, Allison DB, Heymsfield SB, et al: Waist circumference and cardiometabolic risk: a consensus statement from Shaping America's Health: Association for Weight Management and Obesity Prevention; NAASO, the Obesity Society; the American Society for Nutrition; and the American Diabetes Association. Diabetes Care 2007; 30: 1647-1652.
    • (2007) Diabetes Care , vol.30 , pp. 1647-1652
    • Klein, S.1    Allison, D.B.2    Heymsfield, S.B.3
  • 50
    • 33750926474 scopus 로고    scopus 로고
    • Criteria for diagnosing the metabolic syndrome
    • Oda E: Criteria for diagnosing the metabolic syndrome. Am J Clin Nutr 2006; 84: 1251-1252.
    • (2006) Am J Clin Nutr , vol.84 , pp. 1251-1252
    • Oda, E.1
  • 53
    • 33747870163 scopus 로고    scopus 로고
    • Overweight, obesity, and mortality in a large prospective cohort of 50 to 71 years old
    • Adabs KF, Schatzkin A, Harris TB, et al: Overweight, obesity, and mortality in a large prospective cohort of 50 to 71 years old. N Engl J Med 2006; 355: 763-778.
    • (2006) N Engl J Med , vol.355 , pp. 763-778
    • Adabs, K.F.1    Schatzkin, A.2    Harris, T.B.3
  • 54
    • 38149078681 scopus 로고    scopus 로고
    • JPHC Study Group: Body mass index and weight change since 20 years of age and risk of coronary heart disease among Japanese: the Japan Public Health Center-Based Study
    • Chei CL, Iso H, Yamagishi K, Inoue M, Tsugane S, JPHC Study Group: Body mass index and weight change since 20 years of age and risk of coronary heart disease among Japanese: the Japan Public Health Center-Based Study. Int J Obes (Lond) 2008; 32: 144-151.
    • (2008) Int J Obes (Lond) , vol.32 , pp. 144-151
    • Chei, C.L.1    Iso, H.2    Yamagishi, K.3    Inoue, M.4    Tsugane, S.5
  • 55
    • 0019943007 scopus 로고
    • Relation of body fat distribution to metabolic complications of obesity
    • Kissebah AH, Vydelingum N, Murray R, et al: Relation of body fat distribution to metabolic complications of obesity. J Clin Endocrinol Metab 1982; 54: 254-260.
    • (1982) J Clin Endocrinol Metab , vol.54 , pp. 254-260
    • Kissebah, A.H.1    Vydelingum, N.2    Murray, R.3
  • 56
    • 0024564466 scopus 로고
    • Role of deep abdominal fat in the association between regional adipose tissue distribution and glucose tolerance in obese women
    • Despres J, Nadeau A, Tremblay A, et al: Role of deep abdominal fat in the association between regional adipose tissue distribution and glucose tolerance in obese women. Diabetes 1989; 38: 304-309.
    • (1989) Diabetes , vol.38 , pp. 304-309
    • Despres, J.1    Nadeau, A.2    Tremblay, A.3
  • 57
    • 0028299585 scopus 로고
    • Waist circumference and abdominal saggital diameter: Best simple anthropometric indices of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women
    • Pouliot MC, Despres J, Lemieux S, et al: Waist circumference and abdominal saggital diameter: best simple anthropometric indices of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women. Am J Cardiol 1994; 73: 460-468.
    • (1994) Am J Cardiol , vol.73 , pp. 460-468
    • Pouliot, M.C.1    Despres, J.2    Lemieux, S.3
  • 58
    • 15744387573 scopus 로고    scopus 로고
    • Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men
    • Wang Y, Rimm EB, Stampfer MJ, Willett WC, Hu FB: Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men. Am J Clin Nutr 2005; 81: 555-563.
    • (2005) Am J Clin Nutr , vol.81 , pp. 555-563
    • Wang, Y.1    Rimm, E.B.2    Stampfer, M.J.3    Willett, W.C.4    Hu, F.B.5
  • 59
    • 0030923193 scopus 로고    scopus 로고
    • Pathophysiology and molecular mechanism of visceral fat syndrome: The Japanese experience
    • Matsuzawa YM: Pathophysiology and molecular mechanism of visceral fat syndrome: the Japanese experience. Diabetes Metab Rev 1997; 13: 3-13.
    • (1997) Diabetes Metab Rev , vol.13 , pp. 3-13
    • Matsuzawa, Y.M.1
  • 60
    • 34347351228 scopus 로고    scopus 로고
    • Abdominal visceral and subcutaneous adipose tissue compartments. Association with metabolic risk factors in the Framingham Heart Study
    • Fox CS, Massaro JM, Hoffmann U, et al: Abdominal visceral and subcutaneous adipose tissue compartments. Association with metabolic risk factors in the Framingham Heart Study. Circulation 2007; 116: 39-48.
    • (2007) Circulation , vol.116 , pp. 39-48
    • Fox, C.S.1    Massaro, J.M.2    Hoffmann, U.3
  • 61
    • 34948902196 scopus 로고    scopus 로고
    • Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress. The Framingham Heart Study
    • Pou KM, Massaro JM, Hoffmann U, et al: Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress. The Framingham Heart Study. Circulation 2007; 116: 1234-1241.
    • (2007) Circulation , vol.116 , pp. 1234-1241
    • Pou, K.M.1    Massaro, J.M.2    Hoffmann, U.3
  • 62
    • 0035345532 scopus 로고    scopus 로고
    • Skeletal muscle triglyceride. An aspect of regional adiposity and insulin resistance
    • Kelley DE, Goodpaster BH: Skeletal muscle triglyceride. An aspect of regional adiposity and insulin resistance. Diabetes Care 2001; 24: 933-941.
    • (2001) Diabetes Care , vol.24 , pp. 933-941
    • Kelley, D.E.1    Goodpaster, B.H.2
  • 65
  • 66
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-α: Direct role in obesity-linked insulin resistance
    • Hotamisligil GS, Shargill NS, Spiegelman BM: Adipose expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance. Science 1993; 259: 87-91.
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 68
    • 0029980285 scopus 로고    scopus 로고
    • cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (adipose most abundant gene transcript 1)
    • Maeda K, Okubo K, Shimomura I, Funahashi T, Matsuzawa Y, Matsubara K: cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (adipose most abundant gene transcript 1). Biochem Biophy Res Commun 1996; 221: 286-298.
    • (1996) Biochem Biophy Res Commun , vol.221 , pp. 286-298
    • Maeda, K.1    Okubo, K.2    Shimomura, I.3    Funahashi, T.4    Matsuzawa, Y.5    Matsubara, K.6
  • 69
    • 0035905758 scopus 로고    scopus 로고
    • The hormone resistin links obesity to diabetes
    • Steppan CM, Bailey ST, Bhat S, et al: The hormone resistin links obesity to diabetes. Nature 2001; 409: 307-312.
    • (2001) Nature , vol.409 , pp. 307-312
    • Steppan, C.M.1    Bailey, S.T.2    Bhat, S.3
  • 70
    • 19944433652 scopus 로고    scopus 로고
    • Visfatin: A protein secreted by visceral fat that mimicks the effects of insulin
    • Fukuhara A, Matsuda M, Nishizawa M, et al: Visfatin: a protein secreted by visceral fat that mimicks the effects of insulin. Science 2005; 307: 426-430.
    • (2005) Science , vol.307 , pp. 426-430
    • Fukuhara, A.1    Matsuda, M.2    Nishizawa, M.3
  • 71
    • 0344443732 scopus 로고    scopus 로고
    • Adiposity elevates plasma MCP-1 levels leading to the increased CD11b-positive monocytes in mice
    • Takahashi K, Mizuarai S, Araki H, et al: Adiposity elevates plasma MCP-1 levels leading to the increased CD11b-positive monocytes in mice. J Biol Chem 2003; 278: 46654-46660.
    • (2003) J Biol Chem , vol.278 , pp. 46654-46660
    • Takahashi, K.1    Mizuarai, S.2    Araki, H.3
  • 72
    • 22944434929 scopus 로고    scopus 로고
    • Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
    • Yang Q, Graham TE, Mody N, et al: Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature 2005; 436: 356-362.
    • (2005) Nature , vol.436 , pp. 356-362
    • Yang, Q.1    Graham, T.E.2    Mody, N.3
  • 73
    • 33644545704 scopus 로고    scopus 로고
    • Adipocyte fatty acid binding protein a plasma biomarker closely associated with obesity and metabolic syndrome
    • Xu A, Wang Y, Xu JY, et al: Adipocyte fatty acid binding protein a plasma biomarker closely associated with obesity and metabolic syndrome. Clin Chem 2006; 52: 405-413.
    • (2006) Clin Chem , vol.52 , pp. 405-413
    • Xu, A.1    Wang, Y.2    Xu, J.Y.3
  • 74
    • 0034915177 scopus 로고    scopus 로고
    • Insulin inhibits intranuclear nuclear factor kappaB and stimulates IkappaB in mononuclear cells in obese subjects: Evidence for an anti-inflammatory effect?
    • Dandona P, Aljada A, Mohanty P, et al: Insulin inhibits intranuclear nuclear factor kappaB and stimulates IkappaB in mononuclear cells in obese subjects: evidence for an anti-inflammatory effect? J Clin Endocrinol Metab 2001; 86: 3257-3265.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3257-3265
    • Dandona, P.1    Aljada, A.2    Mohanty, P.3
  • 75
    • 33644750396 scopus 로고    scopus 로고
    • 2-terminal kinase pathways in inflammation and origin of obesity and diabetes
    • 2-terminal kinase pathways in inflammation and origin of obesity and diabetes. Diabetes 2006; 54: S73-S78.
    • (2006) Diabetes , vol.54
    • Hotamisligil, G.S.1
  • 76
    • 33745828640 scopus 로고    scopus 로고
    • Insulin resistance and atherosclerosis
    • Semenkovich CF: Insulin resistance and atherosclerosis. J Clin Invest 2006; 116: 1813-1822.
    • (2006) J Clin Invest , vol.116 , pp. 1813-1822
    • Semenkovich, C.F.1
  • 77
    • 34848872799 scopus 로고    scopus 로고
    • Obesity-associated improvements in metabolic profile through expansion of adipose tissue
    • Kim JY, Wall E, Laplante M, et al: Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J Clin Invest 2007; 117: 2621-2637.
    • (2007) J Clin Invest , vol.117 , pp. 2621-2637
    • Kim, J.Y.1    Wall, E.2    Laplante, M.3
  • 78
    • 2542419065 scopus 로고    scopus 로고
    • Visceral obesity without insulin resistance in late-onset obesity rats
    • Bains RK, Wells SE, Flavell DM, et al: Visceral obesity without insulin resistance in late-onset obesity rats. Endocrinology 2004; 145: 2666-2679.
    • (2004) Endocrinology , vol.145 , pp. 2666-2679
    • Bains, R.K.1    Wells, S.E.2    Flavell, D.M.3
  • 79
    • 27444437321 scopus 로고    scopus 로고
    • Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
    • Cinti S, Mitchell G, Barbatelli G, et al: Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res 2005; 46: 2347-2355.
    • (2005) J Lipid Res , vol.46 , pp. 2347-2355
    • Cinti, S.1    Mitchell, G.2    Barbatelli, G.3
  • 80
    • 33745216724 scopus 로고    scopus 로고
    • MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
    • Kanda H, Tateya S, Tamori Y, et al: MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest 2006; 116: 1494-1505.
    • (2006) J Clin Invest , vol.116 , pp. 1494-1505
    • Kanda, H.1    Tateya, S.2    Tamori, Y.3
  • 81
    • 33748750917 scopus 로고    scopus 로고
    • Overexpression of monocyte chemoattractant protein-1 in adipose tissue causes macrophage recruitment and insulin resistance
    • Kamei N, Tobe K, Suzuki R, et al: Overexpression of monocyte chemoattractant protein-1 in adipose tissue causes macrophage recruitment and insulin resistance. J Biol Chem 2006; 281: 26602-26614.
    • (2006) J Biol Chem , vol.281 , pp. 26602-26614
    • Kamei, N.1    Tobe, K.2    Suzuki, R.3
  • 82
    • 34247511496 scopus 로고    scopus 로고
    • Coordinated regulation of nutrient and inflammatory response by STAMP2 is essential for metabolic homeostasis
    • Wellen KE, Fucho R, Gregor MF, et al: Coordinated regulation of nutrient and inflammatory response by STAMP2 is essential for metabolic homeostasis. Cell 2007; 129: 537-548.
    • (2007) Cell , vol.129 , pp. 537-548
    • Wellen, K.E.1    Fucho, R.2    Gregor, M.F.3
  • 83
    • 36849012057 scopus 로고    scopus 로고
    • Adipocyte death, adipose tissue remodeling, and obesity complications
    • Strissel KJ, Stancheva Z, Miyoshi H, et al: Adipocyte death, adipose tissue remodeling, and obesity complications. Diabetes 2007; 56: 2910-2918.
    • (2007) Diabetes , vol.56 , pp. 2910-2918
    • Strissel, K.J.1    Stancheva, Z.2    Miyoshi, H.3
  • 84
    • 34547558619 scopus 로고    scopus 로고
    • Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity
    • Kolak M, Westerbacka J, Velagapudi VR, et al: Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity. Diabetes 2007; 56: 1960-1968.
    • (2007) Diabetes , vol.56 , pp. 1960-1968
    • Kolak, M.1    Westerbacka, J.2    Velagapudi, V.R.3
  • 85
    • 0036833814 scopus 로고    scopus 로고
    • Prospective study of C-reactive protein in relation to the development of diabetes and metabolic syndrome in the Mexico City Diabetes Study
    • Han TS, Satter N, Williams K, Gonzalez-Villalpando C, Lean MEJ, Haffner SM: Prospective study of C-reactive protein in relation to the development of diabetes and metabolic syndrome in the Mexico City Diabetes Study. Diabetes Care 2002; 25: 2016-2021.
    • (2002) Diabetes Care , vol.25 , pp. 2016-2021
    • Han, T.S.1    Satter, N.2    Williams, K.3    Gonzalez-Villalpando, C.4    Lean, M.E.J.5    Haffner, S.M.6
  • 86
    • 0042665536 scopus 로고    scopus 로고
    • Metabolic syndrome with and without C-reactive protein as a predictor of coronary heart disease and diabetes in the West of Scotland Coronary Prevention Study
    • Sattar N, Gaw A, Scherbakova O, et al: Metabolic syndrome with and without C-reactive protein as a predictor of coronary heart disease and diabetes in the West of Scotland Coronary Prevention Study. Circulation 2003; 108: 414-419.
    • (2003) Circulation , vol.108 , pp. 414-419
    • Sattar, N.1    Gaw, A.2    Scherbakova, O.3
  • 87
    • 0141446219 scopus 로고    scopus 로고
    • Elevated C-reactive protein is a risk factor for the development of type 2 diabetes in Japanese Americans
    • Nakanishi S, Yamane K, Kamei N, et al: Elevated C-reactive protein is a risk factor for the development of type 2 diabetes in Japanese Americans. Diabetes Care 2003; 26: 2754-2757.
    • (2003) Diabetes Care , vol.26 , pp. 2754-2757
    • Nakanishi, S.1    Yamane, K.2    Kamei, N.3
  • 88
    • 3242662149 scopus 로고    scopus 로고
    • C-reactive protein, the metabolic syndrome, and prediction of cardiovascular events in the Framingham Offspring Study
    • Rutter MK, Meigs JB, Sullivan LM, D'Agostino RB, Wilson PWF: C-reactive protein, the metabolic syndrome, and prediction of cardiovascular events in the Framingham Offspring Study. Circulation 2004; 110: 380-385.
    • (2004) Circulation , vol.110 , pp. 380-385
    • Rutter, M.K.1    Meigs, J.B.2    Sullivan, L.M.3    D'Agostino, R.B.4    Wilson, P.W.F.5
  • 89
    • 2142695734 scopus 로고    scopus 로고
    • Clinical usefulness of very high and very low levels of C-reactive protein across the full range of Framingham Risk Scores
    • Ridker PM, Cook N: Clinical usefulness of very high and very low levels of C-reactive protein across the full range of Framingham Risk Scores. Circulation 2004; 109: 1955-1959.
    • (2004) Circulation , vol.109 , pp. 1955-1959
    • Ridker, P.M.1    Cook, N.2
  • 90
    • 14644425258 scopus 로고    scopus 로고
    • Cardiovascular disease in
    • U.S. patients with metabolic syndrome, diabetes, and elevated C-reactive protein. Diabetes Care 2005; 28: 690-693
    • Malik S, Wong ND, Franklin S, Pio J, Fairchild C, Chen R: Cardiovascular disease in U.S. patients with metabolic syndrome, diabetes, and elevated C-reactive protein. Diabetes Care 2005; 28: 690-693.
    • Malik, S.1    Wong, N.D.2    Franklin, S.3    Pio, J.4    Fairchild, C.5    Chen, R.6
  • 91
    • 25644437166 scopus 로고    scopus 로고
    • Elevated C-reactive protein is a predictor of the development of diabetes in a general Japanese population
    • Doi Y, Kiyohara Y, Kubo M, et al: Elevated C-reactive protein is a predictor of the development of diabetes in a general Japanese population. Diabetes Care 2005; 28: 2497-2500.
    • (2005) Diabetes Care , vol.28 , pp. 2497-2500
    • Doi, Y.1    Kiyohara, Y.2    Kubo, M.3
  • 93
    • 34247477664 scopus 로고    scopus 로고
    • Prognostic significance of the Centers for Disease Control/American Heart Association high-sensitivity C-reactive protein cut points for cardiovascular and other outcomes in patients with stable coronary artery disease
    • Sabatine MS, Morrow DA, Jablonski KA, et al: Prognostic significance of the Centers for Disease Control/American Heart Association high-sensitivity C-reactive protein cut points for cardiovascular and other outcomes in patients with stable coronary artery disease. Circulation 2007; 115: 1528-1536.
    • (2007) Circulation , vol.115 , pp. 1528-1536
    • Sabatine, M.S.1    Morrow, D.A.2    Jablonski, K.A.3
  • 94
    • 2442581240 scopus 로고    scopus 로고
    • Independent association between plasma leptin and C-reactive protein in healthy humans
    • Shamsuzzaman ASM, Winnicki M, Wolk R, et al: Independent association between plasma leptin and C-reactive protein in healthy humans. Circulation 2004; 109: 2181-2185.
    • (2004) Circulation , vol.109 , pp. 2181-2185
    • Shamsuzzaman, A.S.M.1    Winnicki, M.2    Wolk, R.3
  • 95
    • 33746561419 scopus 로고    scopus 로고
    • Inverse association between adiponectin and C-reactive protein in substantially healthy Japanese men
    • Matsushita K, Yatsuya H, Tamakoshi K, et al: Inverse association between adiponectin and C-reactive protein in substantially healthy Japanese men. Atherosclerosis 2006; 188: 184-189.
    • (2006) Atherosclerosis , vol.188 , pp. 184-189
    • Matsushita, K.1    Yatsuya, H.2    Tamakoshi, K.3
  • 96
    • 38349129860 scopus 로고    scopus 로고
    • Waist circumference is the main determinant of elevated C-reactive protein in metabolic syndrome
    • Nakamura H, Ito H, Egami Y, et al: Waist circumference is the main determinant of elevated C-reactive protein in metabolic syndrome. Diabetes Res Clin Pract 2008; 79: 330-336.
    • (2008) Diabetes Res Clin Pract , vol.79 , pp. 330-336
    • Nakamura, H.1    Ito, H.2    Egami, Y.3
  • 97
    • 34548697275 scopus 로고    scopus 로고
    • Adiponectin inversely correlates with high-sensitivity C-reactive protein and triglycerides, but not with insulin sensitivity in apparently healthy Japanese men
    • Komatsu M, Ohfusa H, Aizawa T, Hashizume K: Adiponectin inversely correlates with high-sensitivity C-reactive protein and triglycerides, but not with insulin sensitivity in apparently healthy Japanese men. Endocrine J 2007; 54: 553-558.
    • (2007) Endocrine J , vol.54 , pp. 553-558
    • Komatsu, M.1    Ohfusa, H.2    Aizawa, T.3    Hashizume, K.4
  • 98
    • 34547596738 scopus 로고    scopus 로고
    • High-sensitivity Creactive protein is an independent clinical feature of nonalcoholic steatohepatitis (NASH) and also of the severity of fibrosis in NASH
    • Yoneda M, Mawatari H, Fujita K, et al: High-sensitivity Creactive protein is an independent clinical feature of nonalcoholic steatohepatitis (NASH) and also of the severity of fibrosis in NASH. J Gastroenterol 2007; 42: 573-582.
    • (2007) J Gastroenterol , vol.42 , pp. 573-582
    • Yoneda, M.1    Mawatari, H.2    Fujita, K.3
  • 99
    • 33645338452 scopus 로고    scopus 로고
    • The optimal cut-off point of C-reactive protein as an optional component of metabolic syndrome in Japan
    • Oda E, Oohara K, Abe A, et al: The optimal cut-off point of C-reactive protein as an optional component of metabolic syndrome in Japan. Circ J 2006; 70: 384-388.
    • (2006) Circ J , vol.70 , pp. 384-388
    • Oda, E.1    Oohara, K.2    Abe, A.3
  • 100
    • 33748919675 scopus 로고    scopus 로고
    • Metabolic syndrome, C-reactive protein and increased arterial stiffness in Japanese subjects
    • Saijo Y, Yoshioka E, Fukui T, Kawaharada M, Kishii R: Metabolic syndrome, C-reactive protein and increased arterial stiffness in Japanese subjects. Hypertens Res 2006; 29: 589-596.
    • (2006) Hypertens Res , vol.29 , pp. 589-596
    • Saijo, Y.1    Yoshioka, E.2    Fukui, T.3    Kawaharada, M.4    Kishii, R.5
  • 101
    • 34249654633 scopus 로고    scopus 로고
    • High-sensitivity C-reactive protein is quite low in Japanese men at high coronary risk
    • Matsushita K, Yatsuya H, Tamakoshi K, et al: High-sensitivity C-reactive protein is quite low in Japanese men at high coronary risk. Circ J 2007; 71: 820-825.
    • (2007) Circ J , vol.71 , pp. 820-825
    • Matsushita, K.1    Yatsuya, H.2    Tamakoshi, K.3
  • 102
    • 34347242035 scopus 로고    scopus 로고
    • Coronary spasm is associated with chronic lowgrade inflammation
    • Itoh T, Mizuno Y, Harada E, Yoshimura M, Ogawa H, Yasue H: Coronary spasm is associated with chronic lowgrade inflammation. Circ J 2007; 71: 1074-1078.
    • (2007) Circ J , vol.71 , pp. 1074-1078
    • Itoh, T.1    Mizuno, Y.2    Harada, E.3    Yoshimura, M.4    Ogawa, H.5    Yasue, H.6
  • 103
    • 34547170053 scopus 로고    scopus 로고
    • The spread of obesity in a large social network over 32 years
    • Christakis NA, Fowler JH: The spread of obesity in a large social network over 32 years. N Engl J Med 2007; 357: 370-379.
    • (2007) N Engl J Med , vol.357 , pp. 370-379
    • Christakis, N.A.1    Fowler, J.H.2


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