Metabolic syndrome: Prevalence and prediction of mortality in elderly individuals

Diabetes Care

Volumn 29, Issue 11, 2006, Pages 2471-2476

  Ravaglia, Giovanni ^a   Forti, Paola ^a   Maioli, Fabiola ^a   Bastagli, Luciana ^a   Chiappelli, Martina ^a   Montesi, Fausta ^a   Bolondi, Luigi ^a   Patterson, Christopher ^b  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERLEUKIN 6; NONSTEROID ANTIINFLAMMATORY AGENT;

AGED; ARTICLE; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; MEDICAL INFORMATION; METABOLIC SYNDROME X; MORTALITY; PREVALENCE; PROGNOSIS; RISK FACTOR;

AGE DISTRIBUTION; AGED; AGED, 80 AND OVER; C-REACTIVE PROTEIN; FEMALE; HUMANS; INTERLEUKIN-6; ITALY; MALE; METABOLIC SYNDROME X; PREDICTIVE VALUE OF TESTS; PREVALENCE; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RISK FACTORS; SEX DISTRIBUTION;

EID: 33845474558     PISSN: 01495992     EISSN: 01495992     Source Type: Journal    
DOI: 10.2337/dc06-0282     Document Type: Article

References (24)

1. Eckel RH, Grundy SM, Zimmet PZ: The metabolic syndrome. Lancet 365:1415-1428, 2005
2. Ford ES: Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome. Diabetes Care 28:1769-1778, 2005
3. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults: Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 285:2486-2497, 2001
4. Cameron AJ, Shaw JE, Zimmet PZ: The metabolic syndrome: prevalence in worldwide populations. Endocrinol Metab Clin North Am 32:351-375, 2004
5. Bonora E, Kiechl S, Willeit J, Oberhollenzer F, Egger G, Bonadonna RC, Muggeo M: Metabolic syndrome: epidemiology and more extensive phenotypic description: cross-sectional data from the Bruneck Study. Int J Obes Relat Metab Disord 27:1283-1289, 2003
6. Miccoli R, Bianchi C, Odoguardi L, Penno G, Caricato F, Giovannitti MG, Pucci L, Del Prato S: Prevalence of the metabolic syndrome among Italian adults according to ATP III definition. Nutr Metab Cardiovasc Dis 15:250-254, 2005
7. Ridker PM, Wilson PWF, Grundy SM: Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk? Circulation 109:2818-2825, 2004
8. Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM: C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA 286:327-334, 2001
9. Ershler WB, Keller ET: Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty. Annu Rev Med 51:245-270, 2000
10. Krabbe KS, Pedersen M, Bruunsgaard H: Inflammatory mediators in the elderly. Exp Gerontol 39:687-699, 2004
11. Tilvis RS, Kahonen-Vare MH, Jolkkonen J, Valvanne J, Pitkala KH, Strandberg TE: Predictors of cognitive decline and mortality of aged people over a 10-year period. J Gerontol A Biol Sci Med Sci 59:268-274, 2004
12. Hu G, Qiao Q, Tuomilehto J, Balkau B, Borch-Johnsen K, Pyorala K: Prevalence of the metabolic syndrome and its relation to all-cause and cardiovascular mortality in nondiabetic European men and women. Arch Intern Med 164:1066-1076, 2004
13. Katzmarzyk PT, Church TS, Blair SN: Cardiorespiratory fitness attenuates the effects of the metabolic syndrome on all-cause and cardiovascular disease mortality in men. Arch Intern Med 164:1092-1097, 2004
14. Ravaglia G, Forti P, Maioli F, Sacchetti L, Mariani E, Nativio V, Talerico T, Vettori C, Macini PL: Education, occupation, and prevalence of dementia: findings from the Conselice Study. Dement Geriatr Cogn Disord 14:90-100, 2002
15. Charlson ME, Pompei P, Ales KL, MacKenzie CR: A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chron Dis 40:373-383, 1987
16. Inelmen EM, Sergi G, Coin A, Miotto F, Peruzza S, Enzi G: Can obesity be a risk factor in elderly people ? Obes Rev 4:147-155, 2003
17. Lee SJ, Lindquist K, Segal MR, Covinsky KE: Development and validation of a prognostic index for 4-year mortality in older adults. JAMA 295:801-808, 2006
18. Hosmer DW, Lemeshow S: Interpretation of a fitted proportional hazards regression model. In Applied Survival Analysis. Hosmer DW, Lemeshow S, Eds. New York, Wiley, 1999, p. 113-157
19. Morley JE, Baumgartner RN: Cytokine-related aging process. J Gerontol Med Sci 59A:924-929, 2004
20. Piche ME, Lemieux S, Weisnagel SJ, Corneau L, Nadeau A, Bergeron J: Relation of high-sensitivity C-reactive protein, interleukin-6, tumor necrosis factor-α, and fibrinogen to abdominal adipose tissue, blood pressure, and cholesterol and triglyceride levels in healthy postmenopausal women. Am J Cardiol 96:92-97, 2005
21. Yudkin JS, Juhan-Vague I, Hawe E, Humphries SE, di Minno G, Margaglione M, Tremoli E, Kooistra T, Morange PE, Lundman P, Mohamed-Ali V, Hamsten A: Low-grade inflammation may play a role in the etiology of the metabolic syndrome in patients with coronary heart disease: the HIFMECH study. Metabolism 53:852-857, 2004
22. Kritchevsky SB, Cesari M, Pahor M: Inflammatory markers and cardiovascular health in older adults. Cardiovasc Res 66:265-275, 2005
23. Harris TB, Ferrucci L, Tracy RP, Corti MC, Wacholder S, Ettinger WH Jr, Heimovitz H, Cohen HJ, Wallace R: Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly. Am J Med 106:506-512, 1999
24. Scuteri A, Najjar SS, Morrell CH, Lakatta EG: The metabolic syndrome in older individuals: prevalence and prediction of cardiovascular events: the Cardiovascular Health Study. Diabetes Care 28:882-887, 2005