Nitrosative stress induces osteoblast apoptosis through downregulating MAPK-mediated NFκB/AP-1 activation and subsequent Bcl-XL expression

Chemico-Biological Interactions

Volumn 184, Issue 3, 2010, Pages 359-365

  Chen, Ta Liang ^a   Wu, Gong Jhe ^a,b   Hsu, Chun Sen ^c   Fong, Tsorng Harn ^d   Chen, Ruei Ming ^c,e  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Bcl XL; MAPKs; NF B AP 1; Nitrosative stress; Osteoblasts

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NITROPRUSSIDE SODIUM; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE; CELL SURVIVAL; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; GENE ACTIVATION; GENE EXPRESSION; GENE TRANSLOCATION; MOLECULAR DYNAMICS; NITROSATIVE STRESS; NONHUMAN; OSTEOBLAST; OXIDATIVE STRESS; PROTEIN PHOSPHORYLATION; RAT;

ANIMALS; APOPTOSIS; BCL-X PROTEIN; DOWN-REGULATION; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASE 9; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE DONORS; NITROPRUSSIDE; NITROSATION; OSTEOBLASTS; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; TRANSCRIPTION FACTOR AP-1;

RATTUS;

EID: 77949918324     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.01.040     Document Type: Article

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