The biphasic effects of nitric oxide in primary rat osteoblasts are cGMP dependent

Biochemical and Biophysical Research Communications

Volumn 274, Issue 2, 2000, Pages 477-481

  Mancini, L ^a   Moradi Bidhendi, N ^a   Becherini, L ^b   Martineti, V ^b   MacIntyre, I ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Alkaline phosphatase; Apoptosis; Cell replication; Nitric oxide; Osteoblasts

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; ALKALINE PHOSPHATASE; CYCLIC GMP; GUANYLATE CYCLASE INHIBITOR; NITRIC OXIDE; SEX HORMONE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOSYNTHESIS; BONE; CARDIOVASCULAR SYSTEM; CATABOLISM; CELL DIVISION; CELL FUNCTION; CENTRAL NERVOUS SYSTEM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; FRACTURE HEALING; IMMUNE SYSTEM; INFLAMMATION; MECHANICAL STRESS; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; RAT; SECOND MESSENGER;

ANIMALIA;

EID: 0034596249     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.3164     Document Type: Article

References (31)

1. S. Moncada R.M.J. Palmer E.A. Higgs Nitric oxide: Physiology, pathophysiology, and pharmacology Pharmacol. Rev. 43 1991 109 141
2. S.S. Gross M.S. Wolin Nitric oxide: Pathophysiological mechanisms Annu. Rev. Physiol. 57 1995 737 769
3. C.W.G.M. Lowik P.H. Nibbering M. van de Ruit S.E. Papapoulos Inducible production of nitric oxide in osteoblast-like cells and in fetal mouse bone explants is associated with suppression of osteoclastic bone resorption J. Clin. Invest. 93 1994 1465 1472
4. S.H. Ralston D. Todd M. Helfrich N. Benjamin P.S. Grabowski Human osteoblast-like cells produce nitric oxide and express inducible nitric oxide synthase Endocrinology 135 1994 330 336
5. J. Klein-Nulend M.H. Helfrich J.G. Sterck H. MacPherson M. Joldersma S.H. Ralston C.M. Semeins E.H. Burger Nitric oxide response to shear stress by human bone cell culture is endothelial nitric oxide synthase dependent Biochem. Biophys. Res. Commun. 250 1998 108 114
6. K.E. Armour S.H. Ralston Estrogen upregulates endothelial constitutive nitric oxide synthase expression in human osteoblast-like cells Endocrinology 139 1998 799 802
7. J.A. Riancho E. Salas M.T. Zarrabeitia J.M. Olmos J.A. Amado J.L. Fernandez-Luna J. Gonzalez-Macias Expression and functional role of nitric oxide synthase in osteoblast-like cells J. Bone Miner. Res. 10 1995 439 445
8. P.S. Grabowski H. MacPherson S.H. Ralston Nitric oxide production in cells derived from the human joint Br. J. Rheum. 35 1996 207 212
9. M.H. Helfrich D.E. Evans P.S. Grabowski J.S. Pollock H. Ohshima S.H. Ralston Expression of nitric oxide synthase isoforms in bone and bone cell cultures J. Bone Miner. Res. 12 1997 1108 1115
10. S.W. Fox J.W.M. Chow Nitric oxide synthase expression in bone cells Bone 23 1998 1 6
11. H. MacPherson B.S. Noble S.H. Ralston Expression and functional role of nitric oxide synthase isoforms in human osteoblast-like cells Bone 24 1999 179 185
12. H. Chae R. Park H. Chung J. Kang M. Kim D. Choi B. Bang H. Kim Nitric oxide is a regulator of bone remodelling J. Pharm. Pharmacol. 49 1997 897 902
13. H. Hikiji W.S. Shin S. Oida T. Takato T. Koizumi T. Toyo-oka Direct action of nitric oxide on osteoblastic differentiation FEBS Lett. 410 1997 238 242
14. E. Otsuka K. Hirano S. Matsushita A. Inoue S. Hirose A. Yamaguchi H. Hagiwara Effects of nitric oxide from exogenous nitric oxide donors on osteoblastic metabolism Eur. J. Pharm. 349 1998 345 350
15. P.D. Damoulis P.V. Hauschka Nitric oxide acts in conjunction with proinflammatory cytokines to promote cell death in osteoblasts J. Bone Miner. Res. 12 1997 412 422
16. R.S. Danziger B.S. Zuckerbraun J.M. Pensler Role of nitric oxide in the regulation of osteoblast metabolism Plast. Rec. Surg. 100 1997 670 673
17. M. Hukkanen F.J. Hughes L.D. Buttery S.S. Gross T.J. Evans S. Seddon V. Riveros-Moreno I. MacIntyre J.M. Polak Cytokine-stimulated expression of inducible nitric oxide synthase by mouse, rat and human osteoblast-like cells and its functional role in osteoblast metabolic activity Endocrinology 136 1995 5445 5453
18. R.L. Jilka R.S. Weinstein T. Bellido A.M. Parfitt S.C. Manolagas Osteoblast programmed cell death (apoptosis): Modulation by growth factors and cytokines J. Bone Miner. Res. 13 1998 793 802
19. M.J. Pead L.E. Lanyon Indomethacin modulation of load-related stimulation of new bone formation in vivo Calcif. Tissue Int. 45 1989 34 40
20. S.W. Fox T.J. Chambers J.W.M. Chow Nitric oxide is an early mediator of the increase in bone formation by mechanical stimulation Am. J. Physiol. 270 1996 E955 E960
21. A.A. Pitsillides S.C.F. Rawlinson R.F.L. Suswillo S. Bourrin G. Zaman L.E. Lanyon Mechanical strain-induced NO production by bone cells: A possible role in adaptive bone (re)modelling? FASEB J. 9 1995 1614 1622
22. C.P. Weiner I. Lizasoain S.A. Baylis R.G. Knowles I.G. Charles S. Moncada Induction of calcium-dependent nitric oxide synthases by sex hormones Proc. Natl. Acad. Sci. USA 91 1994 5212 5216
23. D.R. Bell H.J. Rensberger D.R. Koritnik A. Koshy Estrogen pretreatment directly potentiates endothelium-dependent vasorelaxation of porcine coronary arteries Am. J. Physiol. 268 1995 H377 H383
24. T. Hayashi K. Yamada T. Esaki M. Kuzuya S. Satake T. Ishikawa H. Hidaka A. Iguchi Estrogen increases endothelial nitric oxide by a receptor-mediated system Biochem. Biophys. Res. Commun. 214 1995 847 855
25. S.J. Wimalawansa G. De Marco P. Gaugula C. Yallampalli Nitric oxide donor alleviates ovariectomy-induced bone loss Bone 18 1996 301 304
26. B. Imthurn M. Rosselli A.W. Jaeger P.J. Keller R.K. Dubey Differential effects of hormone-replacement therapy on endogenous nitric oxide (nitrite/nitrate) levels in postmenopausal women substituted with 17β-estradiol valerate and cyproterone acetate or medroxyprogesterone acetate J. Clin. Endocrinol. Metab. 82 1997 388 394
27. A.D. Diwan M.X. Wang D. Jang W. Zhu G.A.C. Murrell Nitric oxide modulates fracture healing J. Bone Miner. Res. 15 2000 342 351
28. C.G. Bellows J.E. Aubin J.N. Heersche M.E. Antosz Mineralised bone nodules formed in vitro from enzymatically released rat calvaria cell populations Calcif. Tissue Int. 38 1986 143 154
29. O.A. Bessey O.H. Lowry M.J. Brock A method for the rapid determination of alkaline phosphatase with five cubic millimetres of serum J. Biol. Chem. 164 1946 321 327
30. M.L. Brandi M. Hukkanen T. Umeda N. Moradi-Bidhendi S. Bianchi S.S. Gross J.M. Polak I. MacIntyre Bidirectional regulation of osteoclast function by nitric oxide synthase isoforms Proc. Natl. Acad. Sci. USA 92 1995 2954 2958
31. R.J. van't Hof S.H. Ralston Cytokine-induced nitric oxide inhibits bone resorption by inducing apoptosis of osteoclast progenitors and suppressing osteoclast activity J. Bone Miner. Res. 12 1997 1797 1804