Cyclooxygenase-2 inhibitor celecoxib augments chemotherapeutic drug-induced apoptosis by enhancing activation of caspase-3 and -9 in prostate cancer cells

International Journal of Cancer

Volumn 115, Issue 3, 2005, Pages 484-492

  Dandekar, Devendra S ^a   Lopez, Monica ^a   Carey, Robert I ^a   Lokeshwar, Bal L ^a,b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MIAMI   (United States)

Author keywords

Chemotherapy; COL 3; Combination therapy; Cyclooxygenase 2 celecoxib; Prostate cancer; Taxotere

Indexed keywords

4 DEDIMETHYLAMINOSANCYCLINE; 5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; CELECOXIB; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DOCETAXEL; INDOMETACIN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAD; PROTEIN BCL XL; X LINKED INHIBITOR OF APOPTOSIS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; COCULTURE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DETERMINATION; STROMA CELL; TUMOR GROWTH;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-ASSOCIATED DEATH PROTEIN; BCL-X PROTEIN; BONE MARROW; CARRIER PROTEINS; CASPASE 3; CASPASE 9; CASPASES; CELL CYCLE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; DRUG THERAPY, COMBINATION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MALE; MEMBRANE PROTEINS; MICE; MICE, NUDE; OSTEOBLASTS; POLY(ADP-RIBOSE) POLYMERASES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTATIC NEOPLASMS; PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRAZOLES; STROMAL CELLS; SULFONAMIDES; TAXOIDS; TUMOR CELLS, CULTURED; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 18644380058     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.20878     Document Type: Article

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