Lipoteichoic acid-induced tnf-α and il-6 gene expressions and oxidative stress production in macrophages are suppressed by ketamine through downregulating toll-like receptor 2-mediated activation of erk1/2 and nfκb

Shock

Volumn 33, Issue 5, 2010, Pages 485-492

  Chang, Huai Chia ^a,b   Lin, Ke Hsun ^c   Tai, Yu Ting ^b   Chen, Juei Tai ^b   Chen, Ruei Ming ^a,b  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Inflammatory cytokines; Ketamine; LTA; Macrophages; Oxidative stress; TLR2

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; KETAMINE; LIPOTEICHOIC ACID; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRITE; PROTEIN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; TEICHOIC ACID;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOSYNTHESIS; CELL NUCLEUS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOPLASM; DRUG BLOOD LEVEL; DRUG INHIBITION; GENE EXPRESSION; GENE REPRESSION; GENE TRANSLOCATION; IMMUNOSTIMULATION; INTRACELLULAR MEMBRANE; MACROPHAGE; MEDIATOR; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; TRANSACTIVATION; TRANSCRIPTION INITIATION; ANIMAL; CELL LINE; DOWN REGULATION; DRUG EFFECTS; METABOLISM; MOUSE; PHYSIOLOGY;

ANIMALS; CELL LINE; DOWN-REGULATION; GENE EXPRESSION; INTERLEUKIN-6; KETAMINE; LIPOPOLYSACCHARIDES; MACROPHAGES; MAP KINASE KINASE 2; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 3; NF-KAPPA B; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; TEICHOIC ACIDS; TOLL-LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77951429357     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3181c3cea5     Document Type: Article

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