메뉴 건너뛰기




Volumn 25, Issue 5, 2007, Pages 625-635

Pretreatment with low nitric oxide protects osteoblasts from high nitric oxide-induced apoptotic insults through regulation of c-Jun N-terminal kinase/c-Jun-mediated Bcl-2 gene expression and protein translocation

Author keywords

Bcl 2; JNK c Jun activation; Nitric oxide; Osteoblasts; Protection

Indexed keywords

ALKALINE PHOSPHATASE; MESSENGER RNA; NITRIC OXIDE; NITROPRUSSIDE SODIUM; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

EID: 34248332630     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20365     Document Type: Article
Times cited : (44)

References (36)
  • 2
    • 0028913960 scopus 로고
    • Bone cell function, regulation, and communication: A role for nitric oxide
    • Collin-Osdoby P, Nickols GA, Osdoby P. 1995. Bone cell function, regulation, and communication: a role for nitric oxide. J Cell Biochem 57:399-408.
    • (1995) J Cell Biochem , vol.57 , pp. 399-408
    • Collin-Osdoby, P.1    Nickols, G.A.2    Osdoby, P.3
  • 3
    • 9244234437 scopus 로고    scopus 로고
    • Regulation of bone mass and bone turnover by neuronal nitric oxide synthase
    • Van't Hof RJ, MacPhee J, Libouban H, et al. 2004. Regulation of bone mass and bone turnover by neuronal nitric oxide synthase. Endocrinology 145:5068-5074.
    • (2004) Endocrinology , vol.145 , pp. 5068-5074
    • Van't Hof, R.J.1    MacPhee, J.2    Libouban, H.3
  • 4
    • 0035139484 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase gene-deficient mice demonstrate marked retardation in postnatal bone formation, reduced bone volume, and defects in osteoblast maturation and activity
    • Aguirre J, Buttery L, O'Shaughnessy M, et al. 2001. Endothelial nitric oxide synthase gene-deficient mice demonstrate marked retardation in postnatal bone formation, reduced bone volume, and defects in osteoblast maturation and activity. Am J Pathol 158:247-257.
    • (2001) Am J Pathol , vol.158 , pp. 247-257
    • Aguirre, J.1    Buttery, L.2    O'Shaughnessy, M.3
  • 5
    • 14244250783 scopus 로고    scopus 로고
    • Molecular mechanism of nitric oxide-induced osteoblast apoptosis
    • Chen RM, Chen TL, Chiu WT, et al. 2005. Molecular mechanism of nitric oxide-induced osteoblast apoptosis. J Orthop Res 23:462-468.
    • (2005) J Orthop Res , vol.23 , pp. 462-468
    • Chen, R.M.1    Chen, T.L.2    Chiu, W.T.3
  • 6
    • 0030980636 scopus 로고    scopus 로고
    • Nitric oxide acts in conjunction with proinflammatory cytokines to promote cell death in osteoblasts
    • Damoulis PD, Hauschka PV. 1997. Nitric oxide acts in conjunction with proinflammatory cytokines to promote cell death in osteoblasts. J Bone Miner Res 12:412-422.
    • (1997) J Bone Miner Res , vol.12 , pp. 412-422
    • Damoulis, P.D.1    Hauschka, P.V.2
  • 7
    • 22044438721 scopus 로고    scopus 로고
    • Nitric oxide induced osteoblast apoptosis through a mitochondrial-dependent pathway
    • Ho WP, Chen TL, Chiu WT, et al. 2005. Nitric oxide induced osteoblast apoptosis through a mitochondrial-dependent pathway. Ann NY Acad Sci 1042:460-470.
    • (2005) Ann NY Acad Sci , vol.1042 , pp. 460-470
    • Ho, W.P.1    Chen, T.L.2    Chiu, W.T.3
  • 8
    • 0033392377 scopus 로고    scopus 로고
    • Evidence for a pathogenic role of nitric oxide in inflammation-induced osteoporosis
    • Armour KE, Van't Hof RJ, Grabowski PS, et al. 1999. Evidence for a pathogenic role of nitric oxide in inflammation-induced osteoporosis. J Bone Miner Res 14:2137-2142.
    • (1999) J Bone Miner Res , vol.14 , pp. 2137-2142
    • Armour, K.E.1    Van't Hof, R.J.2    Grabowski, P.S.3
  • 9
    • 0028967418 scopus 로고
    • Expression and functional role of nitric oxide synthase in osteoblast-like cells
    • Riancho JA, Salas E, Zarrabeitia MT, et al. 1995. Expression and functional role of nitric oxide synthase in osteoblast-like cells. J Bone Min Res 10:439-446.
    • (1995) J Bone Min Res , vol.10 , pp. 439-446
    • Riancho, J.A.1    Salas, E.2    Zarrabeitia, M.T.3
  • 10
    • 0033104154 scopus 로고    scopus 로고
    • Expression and functional role of nitric oxide synthase in osteoblast-like cells
    • MacPherson H, Noble BS, Ralston SH. 1999. Expression and functional role of nitric oxide synthase in osteoblast-like cells. Bone 24:179-185.
    • (1999) Bone , vol.24 , pp. 179-185
    • MacPherson, H.1    Noble, B.S.2    Ralston, S.H.3
  • 11
    • 0035914312 scopus 로고    scopus 로고
    • Nerve growth factor inhibits apoptosis in memory B lymphocytes via inactivation of p38 MAPK, prevention of Bcl-2 phosphorylation, and cytochrome c release
    • Torcia M, De Chiara G, Nencioni L, et al. 2001. Nerve growth factor inhibits apoptosis in memory B lymphocytes via inactivation of p38 MAPK, prevention of Bcl-2 phosphorylation, and cytochrome c release. J Biol Chem 276:39027-39036.
    • (2001) J Biol Chem , vol.276 , pp. 39027-39036
    • Torcia, M.1    De Chiara, G.2    Nencioni, L.3
  • 12
    • 20444481406 scopus 로고    scopus 로고
    • Assessment of a dual regulatory role for NO in liver regeneration after partial hepatectomy: Protection against apoptosis and retardation of hepatocyte proliferation
    • Zeini M, Hortelano S, Traves PG, et al. 2005. Assessment of a dual regulatory role for NO in liver regeneration after partial hepatectomy: protection against apoptosis and retardation of hepatocyte proliferation. FASEB J 19:995-997.
    • (2005) FASEB J , vol.19 , pp. 995-997
    • Zeini, M.1    Hortelano, S.2    Traves, P.G.3
  • 13
    • 0033055982 scopus 로고    scopus 로고
    • Hepatoprotective effect of endogenous nitric oxide during ischemia-reperfusion in the rat
    • Cottart CH, Do L, Blanc MC, et al. 1999. Hepatoprotective effect of endogenous nitric oxide during ischemia-reperfusion in the rat. Hepatology 29:809-813.
    • (1999) Hepatology , vol.29 , pp. 809-813
    • Cottart, C.H.1    Do, L.2    Blanc, M.C.3
  • 14
    • 0031732762 scopus 로고    scopus 로고
    • Estrogen upregulates endothelial constitutive nitric oxide synthase expression in human osteoblast-like cells
    • Armour KE, Ralston SH. 1998. Estrogen upregulates endothelial constitutive nitric oxide synthase expression in human osteoblast-like cells. Endocrinology 139:799-802.
    • (1998) Endocrinology , vol.139 , pp. 799-802
    • Armour, K.E.1    Ralston, S.H.2
  • 15
    • 0347356247 scopus 로고    scopus 로고
    • Oxidative stress inhibits osteoblastic differentiation of bone cells by ERK and NF-κB
    • Bai XC, Lu D, Bai J, et al. 2004. Oxidative stress inhibits osteoblastic differentiation of bone cells by ERK and NF-κB. Biochem Biophys Res Commun 314:197-207.
    • (2004) Biochem Biophys Res Commun , vol.314 , pp. 197-207
    • Bai, X.C.1    Lu, D.2    Bai, J.3
  • 16
    • 0036118189 scopus 로고    scopus 로고
    • Nitric oxide induces osteoblast apoptosis through the de novo synthesis of Bax protein
    • Chen RM, Liu HC, Lin YL, et al. 2002. Nitric oxide induces osteoblast apoptosis through the de novo synthesis of Bax protein. J Orthop Res 20:295-302.
    • (2002) J Orthop Res , vol.20 , pp. 295-302
    • Chen, R.M.1    Liu, H.C.2    Lin, Y.L.3
  • 17
    • 33749832355 scopus 로고    scopus 로고
    • Nitric oxide protects osteoblasts from oxidative stress-induced apoptotic insults via a mitochondria-dependent mechanism
    • Chang CC, Liao YS, Lin YL, et al. 2006. Nitric oxide protects osteoblasts from oxidative stress-induced apoptotic insults via a mitochondria-dependent mechanism. J Orthop Res 24:1917-1925.
    • (2006) J Orthop Res , vol.24 , pp. 1917-1925
    • Chang, C.C.1    Liao, Y.S.2    Lin, Y.L.3
  • 18
    • 0035957653 scopus 로고    scopus 로고
    • Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
    • Wei MC, Zong WX, Cheng EH, et al. 2001. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 292:727-730.
    • (2001) Science , vol.292 , pp. 727-730
    • Wei, M.C.1    Zong, W.X.2    Cheng, E.H.3
  • 19
    • 0032555716 scopus 로고    scopus 로고
    • Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
    • Luo X, Budihardjo I, Zou H, et al. 1998. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94:481-490.
    • (1998) Cell , vol.94 , pp. 481-490
    • Luo, X.1    Budihardjo, I.2    Zou, H.3
  • 20
    • 13944262137 scopus 로고    scopus 로고
    • JNK is associated with Bcl-2 and PP1 in mitochondria: Paclitaxel induces its activation and its association with the phosphorylated form of Bcl-2
    • Brichese L, Cazettes G, Valette A., 2004. JNK is associated with Bcl-2 and PP1 in mitochondria: paclitaxel induces its activation and its association with the phosphorylated form of Bcl-2. Cell Cycle 3:1312-1319.
    • (2004) Cell Cycle , vol.3 , pp. 1312-1319
    • Brichese, L.1    Cazettes, G.2    Valette, A.3
  • 21
    • 27844433521 scopus 로고    scopus 로고
    • PK11195 potently sensitizes to apoptosis induction independently from the peripheral benzodiazepin receptor
    • Gonzalez-Polo RA, Carvalho G, Braun T, et al. 2005. PK11195 potently sensitizes to apoptosis induction independently from the peripheral benzodiazepin receptor. Oncogene 24:7503-7513.
    • (2005) Oncogene , vol.24 , pp. 7503-7513
    • Gonzalez-Polo, R.A.1    Carvalho, G.2    Braun, T.3
  • 23
    • 0034914192 scopus 로고    scopus 로고
    • Cytotoxic and antioxidant effects of the water extract of traditional Chinese herb Gusuibu (Drynaria fortunei) on rat osteoblasts
    • Liu HC, Chen RM, Jian WC, et al. 2001. Cytotoxic and antioxidant effects of the water extract of traditional Chinese herb Gusuibu (Drynaria fortunei) on rat osteoblasts. J Formos Med Assoc 100:383-388.
    • (2001) J Formos Med Assoc , vol.100 , pp. 383-388
    • Liu, H.C.1    Chen, R.M.2    Jian, W.C.3
  • 24
    • 18344377024 scopus 로고    scopus 로고
    • Ketamine reduces nitric oxide biosynthesis in human umbilical vein endothelial cells through downregulating endothelial nitric oxide synthase expression and intracellular calcium levels
    • Chen RM, Chen TL, Lin YL, et al. 2005. Ketamine reduces nitric oxide biosynthesis in human umbilical vein endothelial cells through downregulating endothelial nitric oxide synthase expression and intracellular calcium levels. Crit Care Med 33:1044-1049.
    • (2005) Crit Care Med , vol.33 , pp. 1044-1049
    • Chen, R.M.1    Chen, T.L.2    Lin, Y.L.3
  • 25
    • 15244354051 scopus 로고    scopus 로고
    • Suppressive effects of ketamine on macrophage functions
    • Chang Y, Chen TL, Chiu WT, et al. 2005. Suppressive effects of ketamine on macrophage functions. Toxicol Appl Pharmacol 204:27-35.
    • (2005) Toxicol Appl Pharmacol , vol.204 , pp. 27-35
    • Chang, Y.1    Chen, T.L.2    Chiu, W.T.3
  • 26
    • 22044434600 scopus 로고    scopus 로고
    • Propofol specifically inhibits mitochondrial membrane potential but not complex I NADH dehydrogenase activity thus reducing cellular ATP biosynthesis and migration of macrophages
    • Wu GJ, Tai YT, Chen TL, et al. 2005. Propofol specifically inhibits mitochondrial membrane potential but not complex I NADH dehydrogenase activity thus reducing cellular ATP biosynthesis and migration of macrophages. Ann NY Acad Sci 1042:168-176.
    • (2005) Ann NY Acad Sci , vol.1042 , pp. 168-176
    • Wu, G.J.1    Tai, Y.T.2    Chen, T.L.3
  • 27
    • 0242668724 scopus 로고    scopus 로고
    • Propofol suppresses macrophage functions through modulating mitochondrial membrane potential and cellular adenosine triphosphate levels
    • Chen RM, Wu CH, Chang HC, et al. 2003. Propofol suppresses macrophage functions through modulating mitochondrial membrane potential and cellular adenosine triphosphate levels. Anesthesiology 98:1178-1185.
    • (2003) Anesthesiology , vol.98 , pp. 1178-1185
    • Chen, R.M.1    Wu, C.H.2    Chang, H.C.3
  • 28
    • 0036837622 scopus 로고    scopus 로고
    • Loss of antiapoptotic genes in aging rat crura
    • Yamanaka M, Shirai M, Shiina H, et al. 2002. Loss of antiapoptotic genes in aging rat crura. J Urol 168:2296-2300.
    • (2002) J Urol , vol.168 , pp. 2296-2300
    • Yamanaka, M.1    Shirai, M.2    Shiina, H.3
  • 29
    • 0343191637 scopus 로고    scopus 로고
    • Peroxynitrite production by TNF-α and IL-1β: Implication for suppression of osteoblastic differentiation
    • Hikiji H, Shin WS, Koizumi T, et al. 2000. Peroxynitrite production by TNF-α and IL-1β: implication for suppression of osteoblastic differentiation. Am J Physiol 278: E1031-E1037.
    • (2000) Am J Physiol , vol.278
    • Hikiji, H.1    Shin, W.S.2    Koizumi, T.3
  • 30
    • 0036751225 scopus 로고    scopus 로고
    • Application of the nitric oxide donor SNAP to cardiomyocytes in culture provides protection against oxidative stress
    • Monastyrskaya E, Folarin N, Malyshev I, et al. 2002. Application of the nitric oxide donor SNAP to cardiomyocytes in culture provides protection against oxidative stress. Nitric Oxide 7:127-131.
    • (2002) Nitric Oxide , vol.7 , pp. 127-131
    • Monastyrskaya, E.1    Folarin, N.2    Malyshev, I.3
  • 31
    • 1442308361 scopus 로고    scopus 로고
    • Induction of apoptosis in human leukemia cells by the tyrosine kinase inhibitor adaphostin proceeds through a RAF-1/MEK/ERK-and AKT-dependent process
    • Yu C, Rahmani M, Almenara J, et al. 2004. Induction of apoptosis in human leukemia cells by the tyrosine kinase inhibitor adaphostin proceeds through a RAF-1/MEK/ERK-and AKT-dependent process. Oncogene 23:1364-1376.
    • (2004) Oncogene , vol.23 , pp. 1364-1376
    • Yu, C.1    Rahmani, M.2    Almenara, J.3
  • 32
    • 23744437996 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase (JNK) is required for survival and proliferation of B-lymphoma cells
    • Gururajan M, Chui R, Karuppannan AK, et al. 2005. c-Jun N-terminal kinase (JNK) is required for survival and proliferation of B-lymphoma cells. Blood 106:1382-1391.
    • (2005) Blood , vol.106 , pp. 1382-1391
    • Gururajan, M.1    Chui, R.2    Karuppannan, A.K.3
  • 33
    • 13944274587 scopus 로고    scopus 로고
    • Up-regulation of c-Jun-NH2-kinase pathway contributes to the induction of mitochondria-mediated apoptosis by alpha-tocopheryl succinate in human prostate cancer cells
    • Zu K, Hawthorn L, Ip C. 2005. Up-regulation of c-Jun-NH2-kinase pathway contributes to the induction of mitochondria-mediated apoptosis by alpha-tocopheryl succinate in human prostate cancer cells. Mol Cancer Ther 4: 43-50.
    • (2005) Mol Cancer Ther , vol.4 , pp. 43-50
    • Zu, K.1    Hawthorn, L.2    Ip, C.3
  • 34
    • 0242691046 scopus 로고    scopus 로고
    • AP-1: A double-edged sword in tumorigenesis
    • Eferl R, Wagner EF. 2003. AP-1: a double-edged sword in tumorigenesis. Nat Rev Cancer 3:859-868.
    • (2003) Nat Rev Cancer , vol.3 , pp. 859-868
    • Eferl, R.1    Wagner, E.F.2
  • 35
    • 29244472037 scopus 로고    scopus 로고
    • Akt phosphorylates and regulates Pdcd4 tumor suppressor protein
    • Palamarchuk A, Efanov A, Maximov V, et al. 2005. Akt phosphorylates and regulates Pdcd4 tumor suppressor protein. Cancer Res 65:11282-11286.
    • (2005) Cancer Res , vol.65 , pp. 11282-11286
    • Palamarchuk, A.1    Efanov, A.2    Maximov, V.3
  • 36
    • 0242290324 scopus 로고    scopus 로고
    • Astrocyte protection of neurons: Role of transforming growth factor-beta signaling via a c-Jun-AP-1 protective pathway
    • Dhandapani KM, Hadman M, De Sevilla L, et al. 2003. Astrocyte protection of neurons: role of transforming growth factor-beta signaling via a c-Jun-AP-1 protective pathway. J Biol Chem 278:43329-43339.
    • (2003) J Biol Chem , vol.278 , pp. 43329-43339
    • Dhandapani, K.M.1    Hadman, M.2    De Sevilla, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.