Oxidized low-density lipoprotein induces apoptotic insults to mouse cerebral endothelial cells via a Bax-mitochondria-caspase protease pathway

Toxicology and Applied Pharmacology

Volumn 219, Issue 1, 2007, Pages 42-53

  Chen, Tyng Guey ^a   Chen, Ta Liang ^b   Chang, Huai Chia ^a   Tai, Yu Ting ^a   Cherng, Yih Giun ^a   Chang, Ya Ting ^c   Chen, Ruei Ming ^a,c,d  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Bax translocation; Caspase activation; Cerebral endothelial cells; Cytochrome c release; Mitochondrial dysfunction; Oxidized LDL

Indexed keywords

BENZYLOXYCARBONYLVALYLGLUTAMYLISOLEUCYLASPARTIC ACID FLUOROMETHYLKETONE; BLOOD CLOTTING FACTOR 8; CASPASE 3; CASPASE 6; CASPASE 9; CYTOCHROME C; DNA FRAGMENT; OXIDIZED LOW DENSITY LIPOPROTEIN; PROTEIN BAX; PROTEINASE; UNCLASSIFIED DRUG; VIMENTIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CELL; CELL CULTURE; CELL CYCLE; CELL DAMAGE; CELL ISOLATION; CONCENTRATION RESPONSE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CULTURE MEDIUM; CYTOPLASM; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EVALUATION; IMAGE ANALYSIS; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TIME;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASES; CELL SURVIVAL; CELLS, CULTURED; CYTOCHROMES C; DNA FRAGMENTATION; ENDOTHELIAL CELLS; IMMUNOHISTOCHEMISTRY; LIPOPROTEINS, LDL; MEMBRANE POTENTIALS; MICE; MICROSCOPY, CONFOCAL; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; NADH DEHYDROGENASE; OXIDATION-REDUCTION; PEPTIDE HYDROLASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 33846867270     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2006.11.031     Document Type: Article

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