High-resolution and high-throughput protocols for measuring drug/human serum albumin interactions using BIACORE

Analytical Biochemistry

Volumn 296, Issue 2, 2001, Pages 197-207

  Rich, Rebecca L ^a   Day, Yasmina S N ^a   Morton, Thomas A ^a   Myszka, David G ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Bound; ADME; Affinity; Drug screening; HSA; SPR

Indexed keywords

BINDING ENERGY; BIOSENSORS; DISSOCIATION; EQUILIBRIUM CONSTANTS; PROTEINS; RATE CONSTANTS;

% BOUND; ADME; AFFINITY; AUTOMATED INSTRUMENTATION; DISSOCIATION RATE CONSTANT; DRUG SCREENING; EQUILIBRIUM DISSOCIATION CONSTANT; HIGH-THROUGHPUT PROTOCOLS;

DRUG INTERACTIONS;

ALBUMIN; WARFARIN;

ARTICLE; AUTOMATION; BIOSENSOR; DRUG PROTEIN BINDING; HUMAN; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION; REPRODUCIBILITY; SERUM;

EID: 0035884143     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1006/abio.2001.5314     Document Type: Article

References (64)