Helper T cell epitope-mapping reveals MHC-peptide binding affinities that correlate with T helper cell responses to pneumococcal surface protein A

PLoS ONE

Volumn 5, Issue 2, 2010, Pages

  Singh, Rajesh ^a   Singh, Shailesh ^b   Sharma, Praveen K ^b   Singh, Udai P ^c   Briles, David E ^d   Hollingshead, Susan K ^d   Lillard Jr , James W ^a  

^a MOREHOUSE SCHOOL OF MEDICINE   (United States)

^b University of Louisville School of Medicine   (United States)

^c UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; BACTERIAL PROTEIN; CD4 ANTIGEN; CYTOKINE; EPITOPE; GAMMA INTERFERON; HLA ANTIGEN; HLA DP ANTIGEN; HLA DQ ANTIGEN; HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; MAJOR HISTOCOMPATIBILITY ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PNEUMOCOCCAL SURFACE PROTEIN A; UNCLASSIFIED DRUG; HISTOCOMPATIBILITY ANTIGEN; HLA ANTIGEN CLASS 2; PEPTIDE;

ALLELE; ARTICLE; BACTERIAL STRAIN; BINDING AFFINITY; CD4+ T LYMPHOCYTE; CELL ISOLATION; CELL PROLIFERATION; CERVICAL LYMPH NODE; COMPUTER MODEL; CONTROLLED STUDY; EX VIVO STUDY; GENE MAPPING; HELPER CELL; IN VIVO CULTURE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PREDICTION; PROTEIN BINDING; PROTEIN INTERACTION; SPLEEN; STREPTOCOCCUS PNEUMONIAE; AMINO ACID SEQUENCE; ANIMAL; BAGG ALBINO MOUSE; BINDING COMPETITION; CYTOLOGY; EPITOPE MAPPING; FEMALE; GENETICS; HUMAN; IMMUNOLOGY; MALE; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; MOUSE STRAIN; PNEUMOCOCCAL INFECTION;

MURINAE; MUS; STREPTOCOCCUS;

AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; BINDING, COMPETITIVE; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CYTOKINES; EPITOPE MAPPING; EPITOPES, T-LYMPHOCYTE; FEMALE; HISTOCOMPATIBILITY ANTIGENS; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED STRAINS; MOLECULAR SEQUENCE DATA; PEPTIDES; PNEUMOCOCCAL INFECTIONS; PROTEIN BINDING; STREPTOCOCCUS PNEUMONIAE; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 77949728403     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009432     Document Type: Article

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