Cloning, isolation, and characterization of mammalian legumain, an asparaginyl endopeptidase

Journal of Biological Chemistry

Volumn 272, Issue 12, 1997, Pages 8090-8098

  Chen, Jinq May ^a   Dando, Pam M ^a   Rawlings, Neil D ^a   Brown, Molly A ^a   Young, Nina E ^a   Stevens, Richard A ^a   Hewittt, Eric ^b   Watts, Colin ^b   Barrett, Alan J ^a  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE;

ARTICLE; DEGLYCOSYLATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; KIDNEY; MAMMAL; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ISOLATION; PROTEIN LOCALIZATION; SWINE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CATALYSIS; CLONING, MOLECULAR; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DNA, COMPLEMENTARY; GLYCOSYLATION; HUMANS; HYDROLYSIS; KIDNEY; KINETICS; MOLECULAR SEQUENCE DATA; PLANT PROTEINS; RABBITS; RATS; RATS, WISTAR; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; SWINE;

EID: 0030992979     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.12.8090     Document Type: Article

References (21)

1. Rawlings, N. D., and Barrett, A. J. (1994) Methods Enzymol. 244, 461-486
2. Barrett, A. J., and Rawlings, N. D. (1996) Perspect. Drug Discov. Design 6, 1-11
3. Kembhavi, A. A., Buttle, D. J., Knight, C. G., and Barrett, A. J. (1993) Arch. Biochem. Biophys. 303, 208-213
4. Hara-Nishimura, L, Takeuchi, Y., and Nishimura, M. (1993) Plant Cell 5, 1651-1659
5. Dalton, J. P., Hola-Jamriska, L., and Brindley, P. J. (1995) Parasitology 111, 575-580
6. Dawson, R. M. C., Elliott, D. C., Elliott, W. H., and Jones, K. M. (1987) Data for Biochemical Research, p. 427, Clarendon Press, Oxford, United Kingdom
7. Anastasi, A., Brown, M. A., Kembhavi, A. A., Nicklin, M. J. H., Sayers, C. A., Sunter, D. C., and Barrett, A. J. (1933) Biochem. J. 211, 129-138
8. Barrett, A. J. (1981) Methods Enzymol. 80, 771-778
9. Barrett, A. J., Kembhavi, A. A., Brown, M. A., Kirschke, II., Knight, C. G., Tamai, M., and Hanada, K. (1982) Biochem. J. 201, 189-198
10. Barrett, A. J., and Kirschke, H. (1981) Methods Enzymol. 80, 535-561
11. Lundberg, K. S., Shoemaker, S. D., Adams, M. W. W., Short, J. M., Sorge, J. A., and Mathur, E. J. (1991) Gene (Amst.) 108, 1-6
12. Sanger, F., Nicklen, S., and Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U. S. A. 74, 5463-5467
13. Frohman, M. A., Dush, M. K., and Martin, G. R. (1988) Proc. Natl. Acad. Sci. U. S. A. 83, 8998-9002
14. Bury, A. F. (1981) J. Chromatogr. 213, 491-500
15. Rawlings, N. D., and Barrett, A. J. (1990) Comput. Appl. Biosci. 6, 118-119
16. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
17. Kozak, M. (1991) J. Biol. Chem. 266, 19867-19870
18. Genetics Computer Group ( 1991) Program Manual for the Wisconsin Package, Version 8, University of Wisconsin, Madison, WI
19. Rice, P. (1995) Program Manual for the EGCG Package, The Sanger Centre, Hinxton, Cambridge, United Kingdom
20. Ruoslahti, E., and Pierschbacher, M. D. (1986) Cell 44, 517-518
21. D'Souza, S. E., Ginsberg, M. II., and Plow, E. F. (1991) Trends Biochem. Sci. 16, 246-250