Familial Alzheimer's disease mutations in presenilin 1 do not alter levels of the secreted amyloid-β protein precursor generated by β-secretase cleavage

Current Alzheimer Research

Volumn 7, Issue 1, 2010, Pages 21-26

  Zhang, C ^a   Browne, A ^a   Kim, D Y ^a   Tanzi, R E ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Alzheimer's disease; APP; FAD mutation; N APP; PSEN1; sAPP

Indexed keywords

AMINO ACID; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; PRESENILIN 1; PRESENILIN 2;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENETIC IDENTIFICATION; HUMAN; HUMAN CELL; MAMMAL CELL; MUTATION; NERVE DEGENERATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BLOTTING, WESTERN; CELL LINE; CHO CELLS; CRICETINAE; CRICETULUS; DNA MUTATIONAL ANALYSIS; HUMANS; MICE; MUTATION; PRESENILIN-1; TRANSFECTION;

EID: 77949728358     PISSN: 15672050     EISSN: None     Source Type: Journal    
DOI: 10.2174/156720510790274428     Document Type: Article

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