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Volumn 205, Issue 1, 2010, Pages 37-47

Diminished diet-induced hyperglycemia and dyslipidemia and enhanced expression of PPARaα and FGF21 in mice with hepatic ablation of brain-derived neurotropic factor

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BRAIN DERIVED NEUROTROPHIC FACTOR; CHOLESTEROL; FIBROBLAST GROWTH FACTOR 21; GLUCOSE; INSULIN; LIPID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; TRIACYLGLYCEROL;

EID: 77949508276     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1677/JOE-09-0405     Document Type: Article
Times cited : (42)

References (51)
  • 1
    • 1842480297 scopus 로고    scopus 로고
    • Nonalcoholic fatty liverdisease among patients with hypothalamic and pituitary dysfunction
    • Adams LA, Feldstein A, Lindor KD & Angulo P 2004 Nonalcoholic fatty liverdisease among patients with hypothalamic and pituitary dysfunction. Hepatology 39 909-914.
    • (2004) Hepatology , vol.39 , pp. 909-914
    • Adams, L.A.1    Feldstein, A.2    Lindor, K.D.3    Angulo, P.4
  • 3
    • 34249711964 scopus 로고    scopus 로고
    • Hepatic fibroblast growth factor 21 is regulated by PPARα and is a key mediator of hepatic lipid metabolism in ketotic states
    • Badman MK, Pissios P, Kennedy AR, Koukos G, Flier JS & Maratos-Flier E 2007 Hepatic fibroblast growth factor 21 is regulated by PPARα and is a key mediator of hepatic lipid metabolism in ketotic states. Cell Metabolism 5 426-437.
    • (2007) Cell Metabolism , vol.5 , pp. 426-437
    • Badman, M.K.1    Pissios, P.2    Kennedy, A.R.3    Koukos, G.4    Flier, J.S.5    Maratos-Flier, E.6
  • 8
    • 0035200716 scopus 로고    scopus 로고
    • Human and rat hepatic stellate cells express neurotrophins and neurotrophin receptors
    • Cassiman D, Denef C, Desmet VJ & Roskams T 2001 Human and rat hepatic stellate cells express neurotrophins and neurotrophin receptors. Hepatology 33 148-158.
    • (2001) Hepatology , vol.33 , pp. 148-158
    • Cassiman, D.1    Denef, C.2    Desmet, V.J.3    Roskams, T.4
  • 10
    • 66549097241 scopus 로고    scopus 로고
    • Fibroblast growth factor 21: A novel metabolic regulator with potential therapeutic properties in obesity/type 2 diabetes mellitus
    • Dostalova I, Haluzikova D & Haluzik M 2009 Fibroblast growth factor 21: a novel metabolic regulator with potential therapeutic properties in obesity/type 2 diabetes mellitus. Physiological Research 58 1-7.
    • (2009) Physiological Research , vol.58 , pp. 1-7
    • Dostalova, I.1    Haluzikova, D.2    Haluzik, M.3
  • 11
    • 0026442248 scopus 로고
    • Cells expressing mRNA for neurotrophins and their receptors during embryonic rat development
    • Ernfors P, Merlio JP & Persson H 1992 Cells expressing mRNA for neurotrophins and their receptors during embryonic rat development. European Journal of Neuroscience 4 1140-1158.
    • (1992) European Journal of Neuroscience , vol.4 , pp. 1140-1158
    • Ernfors, P.1    Merlio, J.P.2    Persson, H.3
  • 15
    • 0034653422 scopus 로고    scopus 로고
    • BDNF regulates eating behavior and locomotor activity in mice
    • Kernie SG, Liebl DJ & Parada LF 2000 BDNF regulates eating behavior and locomotor activity in mice. EMBO Journal 19 1290-1300.
    • (2000) EMBO Journal , vol.19 , pp. 1290-1300
    • Kernie, S.G.1    Liebl, D.J.2    Parada, L.F.3
  • 20
    • 4944238844 scopus 로고    scopus 로고
    • Role of the liver in the control of glucose-lipid utilization and body weight
    • Langhans W 2003 Role of the liver in the control of glucose-lipid utilization and body weight. Current Opinion in Clinical Nutrition and Metabolic Care 6 449-455.]
    • (2003) Current Opinion in Clinical Nutrition and Metabolic Care , vol.6 , pp. 449-455
    • Langhans, W.1
  • 26
    • 0033592920 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities
    • Lyons WE, Mamounas LA, Ricaurte GA, Coppola V, Reid SW, Bora SH, Wihler C, Koliatsos VE & Tessarollo L 1999 Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities. PNAS 96 15239-15244.
    • (1999) PNAS , vol.96 , pp. 15239-15244
    • Lyons, W.E.1    Mamounas, L.A.2    Ricaurte, G.A.3    Coppola, V.4    Reid, S.W.5    Bora, S.H.6    Wihler, C.7    Koliatsos, V.E.8    Tessarollo, L.9
  • 28
    • 33745009522 scopus 로고    scopus 로고
    • BDNF is expressed in skeletal muscle satellite cells and inhibits myogenic differentiation
    • Mousavi K & Jasmin BJ 2006 BDNF is expressed in skeletal muscle satellite cells and inhibits myogenic differentiation. Journal of Neuroscience 26 5739-5749.
    • (2006) Journal of Neuroscience , vol.26 , pp. 5739-5749
    • Mousavi, K.1    Jasmin, B.J.2
  • 32
    • 0034059141 scopus 로고    scopus 로고
    • DNA excision in liver by an albumin-Cre transgene occurs progressively with age
    • Postic C & Magnuson MA 2000 DNA excision in liver by an albumin-Cre transgene occurs progressively with age. Genesis 26 149-150.
    • (2000) Genesis , vol.26 , pp. 149-150
    • Postic, C.1    Magnuson, M.A.2
  • 33
    • 41549158345 scopus 로고    scopus 로고
    • Sex-differential expression of metabolism-related genes in response to a high-fat diet
    • Priego T, Sanchez J, Pico C & Palou A 2008 Sex-differential expression of metabolism-related genes in response to a high-fat diet. Obesity 16 819-826.
    • (2008) Obesity , vol.16 , pp. 819-826
    • Priego, T.1    Sanchez, J.2    Pico, C.3    Palou, A.4
  • 34
    • 63449112017 scopus 로고    scopus 로고
    • Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation
    • Purushotham A, Schug TT, Xu Q, Surapureddi S, Guo X & Li X 2009 Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation. Cell Metabolism 9 327-338.
    • (2009) Cell Metabolism , vol.9 , pp. 327-338
    • Purushotham, A.1    Schug, T.T.2    Xu, Q.3    Surapureddi, S.4    Guo, X.5    Li, X.6
  • 35
    • 33644674139 scopus 로고    scopus 로고
    • Gender differences in the metabolic syndrome and their role for cardiovascular disease
    • Regitz-Zagrosek V, Lehmkuhl E &Weickert MO 2006 Gender differences in the metabolic syndrome and their role for cardiovascular disease. Clinical Research in Cardiology 95 136-147.
    • (2006) Clinical Research in Cardiology , vol.95 , pp. 136-147
    • Regitz-Zagrosek, V.1    Lehmkuhl, E.2    Weickert, M.O.3
  • 36
    • 0034792085 scopus 로고    scopus 로고
    • Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity
    • Rios M, Fan G, Fekete C, Kelly J, Bates B, Kuehn R, Lechan RM & Jaenisch R 2001 Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. Molecular Endocrinology 15 1748-1757.
    • (2001) Molecular Endocrinology , vol.15 , pp. 1748-1757
    • Rios, M.1    Fan, G.2    Fekete, C.3    Kelly, J.4    Bates, B.5    Kuehn, R.6    Lechan, R.M.7    Jaenisch, R.8
  • 37
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano P 1999 Generalized lacZ expression with the ROSA26 Cre reporter strain. Nature Genetics 21 70-71.
    • (1999) Nature Genetics , vol.21 , pp. 70-71
    • Soriano, P.1
  • 38
    • 58949097577 scopus 로고    scopus 로고
    • A comprehensive collection of experimentally validated primers for polymerase chain reaction quantitation of murine transcript abundance
    • Spandidos A, Wang X, Wang H, Dragnev S, Thurber T & Seed B 2008 A comprehensive collection of experimentally validated primers for polymerase chain reaction quantitation of murine transcript abundance. BMC Genomics 9 633.
    • (2008) BMC Genomics , vol.9 , pp. 633
    • Spandidos, A.1    Wang, X.2    Wang, H.3    Dragnev, S.4    Thurber, T.5    Seed, B.6
  • 41
    • 12244305762 scopus 로고    scopus 로고
    • Gut-derived signaling molecules and vagal afferents in the control of glucose and energy homeostasis
    • Thorens B & Larsen PJ 2004 Gut-derived signaling molecules and vagal afferents in the control of glucose and energy homeostasis. Current Opinion in Clinical Nutrition and Metabolic Care 7 471-478.
    • (2004) Current Opinion in Clinical Nutrition and Metabolic Care , vol.7 , pp. 471-478
    • Thorens, B.1    Larsen, P.J.2
  • 42
    • 0033005143 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor improves blood glucose control and alleviates fasting hyperglycemia in C57BLKS-Lepr(db)/ lepr(db) mice
    • Tonra JR, Ono M, Liu X, Garcia K, Jackson C, Yancopoulos GD,Wiegand SJ &Wong V 1999 Brain-derived neurotrophic factor improves blood glucose control and alleviates fasting hyperglycemia in C57BLKS-Lepr(db)/ lepr(db) mice. Diabetes 48 588-594.
    • (1999) Diabetes , vol.48 , pp. 588-594
    • Tonra, J.R.1    Ono, M.2    Liu, X.3    Garcia, K.4    Jackson, C.5    Yancopoulos, G.D.6    Wiegand, S.J.7    Wong, V.8
  • 43
    • 0035025080 scopus 로고    scopus 로고
    • The effects of brain-derived neurotrophic factor on insulin signal transduction in the liver of diabetic mice
    • Tsuchida A, Nakagawa T, Itakura Y, Ichihara J, OgawaW,Kasuga M, TaijiM& NoguchiH2001 The effects of brain-derived neurotrophic factor on insulin signal transduction in the liver of diabetic mice. Diabetologia 44 555-566.
    • (2001) Diabetologia , vol.44 , pp. 555-566
    • Tsuchida, A.1    Nakagawa, T.2    Itakura, Y.3    Ichihara, J.4    OgawaW5    Kasuga, M.6    TaijiM7    NoguchiH8
  • 45
    • 37549055474 scopus 로고    scopus 로고
    • Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity
    • Unger TJ, Calderon GA, Bradley LC, Sena-Esteves M & Rios M 2007 Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity. Journal of Neuroscience 27 14265-14274.
    • (2007) Journal of Neuroscience , vol.27 , pp. 14265-14274
    • Unger, T.J.1    Calderon, G.A.2    Bradley, L.C.3    Sena-Esteves, M.4    Rios, M.5
  • 46
    • 33846225653 scopus 로고    scopus 로고
    • Targeted disruption of the hepatic transferrin receptor 2 gene in mice leads to iron overload
    • Wallace DF, Summerville L & Subramaniam VN 2007 Targeted disruption of the hepatic transferrin receptor 2 gene in mice leads to iron overload. Gastroenterology 132 301-310.
    • (2007) Gastroenterology , vol.132 , pp. 301-310
    • Wallace, D.F.1    Summerville, L.2    Subramaniam, V.N.3
  • 47
    • 85074914953 scopus 로고    scopus 로고
    • A PCR primer bank for quantitative gene expression analysis
    • Wang X & Seed B 2003 A PCR primer bank for quantitative gene expression analysis. Nucleic Acids Research 31 e154.
    • (2003) Nucleic Acids Research , vol.31
    • Wang, X.1    Seed, B.2
  • 49
    • 20944447890 scopus 로고    scopus 로고
    • Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice
    • Xu A, Lam MC, Chan KW, Wang Y, Zhang J, Hoo RL, Xu JY, Chen B, Chow WS, Tso AWet al. 2005 Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice. PNAS 102 6086-6091.
    • (2005) PNAS , vol.102 , pp. 6086-6091
    • Xu, A.1    Lam, M.C.2    Chan, K.W.3    Wang, Y.4    Zhang, J.5    Hoo, R.L.6    Xu, J.Y.7    Chen, B.8    Chow, W.S.9    Tso, A.W.10
  • 50
    • 61649127208 scopus 로고    scopus 로고
    • Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice
    • Xu J, Lloyd DJ, Hale C, Stanislaus S, Chen M, Sivits G, Vonderfecht S, Hecht R, Li YS, Lindberg RA et al. 2009 Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice. Diabetes 58 250-259.
    • (2009) Diabetes , vol.58 , pp. 250-259
    • Xu, J.1    Lloyd, D.J.2    Hale, C.3    Stanislaus, S.4    Chen, M.5    Sivits, G.6    Vonderfecht, S.7    Hecht, R.8    Li, Y.S.9    Lindberg, R.A.10
  • 51
    • 0027986870 scopus 로고
    • Plasticity of tyrosine hydroxylase and vasoactive intestinal peptide messenger RNAs in visceral afferent neurons of the nodose ganglion upon axotomy-induced deafferentation
    • Zhuo H, Sinclair C & Helke CJ 1994 Plasticity of tyrosine hydroxylase and vasoactive intestinal peptide messenger RNAs in visceral afferent neurons of the nodose ganglion upon axotomy-induced deafferentation. Neuroscience 63 617-626.
    • (1994) Neuroscience , vol.63 , pp. 617-626
    • Zhuo, H.1    Sinclair, C.2    Helke, C.J.3


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