Molecular mechanism of allosteric communication in the human PPARα-RXRα heterodimer

Proteins: Structure, Function and Bioinformatics

Volumn 78, Issue 4, 2010, Pages 873-887

  Venäläinen, Thomas ^a   Moinar, Ferdinand ^a,b   Oostenbrink, Chris ^c   Carlberg, Carsten ^a,d   Peräkylä, Mikael ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^c VU UNIVERSITY AMSTERDAM   (Netherlands)

^d UNIVERSITY OF LUXEMBOURG   (Luxembourg)

Author keywords

Activation; Molecular dynamics; Nuclear receptors; Point mutations; Protein protein interactions

Indexed keywords

HELIX LOOP HELIX PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; RETINOID X RECEPTOR ALPHA;

ARTICLE; BINDING SITE; DIMERIZATION; LIGAND BINDING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STABILITY; ALLOSTERISM; CELL LINE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE;

ALLOSTERIC REGULATION; CELL LINE; HUMANS; MOLECULAR DYNAMICS SIMULATION; PPAR ALPHA; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; RETINOID X RECEPTOR ALPHA;

EID: 77949317976     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22613     Document Type: Article

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