Biodistribution, toxicity and radiation dosimetry studies of the serotonin transporter radioligand 4-[18F]-ADAM in rats and monkeys

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 37, Issue 3, 2010, Pages 545-555

  Huang, Ya Yao ^a,b   Ma, Kuo Hsing ^c   Tseng, Ta Wei ^a   Chou, Ta Kai ^a   Ng, Hanna ^d   Mirsalis, Jon C ^d   Fu, Ying Kai ^e,f   Chu, Tieh Chi ^b,g   Huang, Wen Sheng ^a   Shiue, Chyng Yann ^a,h  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^b NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^d SRI INTERNATIONAL   (United States)

^e INSTITUTE OF NUCLEAR ENERGY RESEARCH   (Taiwan)

^f CHUNG YUAN CHRISTIAN UNIVERSITY   (Taiwan)

^g YUANPEI UNIVERSITY   (Taiwan)

^h UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

4 18F ADAM; Radiation dosimetry; Serotonin transporter imaging agent; Toxicity

Indexed keywords

N,N DIMETHYL 2 (2 AMINO 4 FLUOROPHENYLTHIO)BENZYLAMINE F 18; RADIOLIGAND; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLADDER; COMPUTED TOMOGRAPHY SCANNER; COMPUTER PROGRAM; CONTROLLED STUDY; DOSIMETRY; DRUG DISTRIBUTION; DRUG SAFETY; EXPERIMENTAL MONKEY; FEMALE; MALE; NONHUMAN; RADIATION ABSORPTION; RADIATION DOSE; RAT; TIME; TOXICITY TESTING; WHOLE BODY CT; WHOLE BODY PET;

ADULT; ANIMALS; BENZYLAMINES; FEMALE; FLUORINE RADIOISOTOPES; HAPLORHINI; HUMANS; MALE; RADIATION DOSAGE; RADIOLIGAND ASSAY; RADIOMETRY; RATS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; TISSUE DISTRIBUTION;

EID: 77949271534     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-009-1281-z     Document Type: Article

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