N,N-dimethyl-2-(2-amino-4- 18F-fluorophenylthio)-benzylamine (4- 18F-ADAM): An improved PET radioligand for serotonin transporters

Journal of Nuclear Medicine

Volumn 44, Issue 12, 2003, Pages 1890-1897

  Shiue, Grace G ^a   Choi, Seok Rye ^a   Fang, Ping ^a   Hou, Catherine ^a   Acton, Paul D ^a   Cardi, Chris ^a   Saffer, Janet R ^a   Greenberg, Joel H ^a   Karp, Joel S ^a   Kung, Hank F ^a   Shiue, Chyng Yann ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

4 18F ADAM; PET; Serotonin transporter imaging agent

Indexed keywords

ACETIC ACID ETHYL ESTER; DOPAMINE TRANSPORTER; FLUORINE 18; METHYLPHENIDATE; N,N DIMETHYL 2 (2 AMINO 4 FLUOROPHENYLTHIO)BENZYLAMINE F 18; NISOXETINE; NORADRENALIN TRANSPORTER; RADIOLIGAND; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG; BENZYLAMINE DERIVATIVE; CARRIER PROTEIN; DIAGNOSTIC AGENT; LIGAND; MEMBRANE PROTEIN; N,N DIMETHYL 2 (2 AMINO 4 FLUOROPHENYLTHIO)BENZYLAMINE; N,N-DIMETHYL-2-(2-AMINO-4-FLUOROPHENYLTHIO)BENZYLAMINE; NERVE PROTEIN; RADIOPHARMACEUTICAL AGENT; SLC6A4 PROTEIN, RAT;

ANIMAL EXPERIMENT; ARTICLE; BABOON; BINDING AFFINITY; BINDING SITE; CEREBELLUM; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORPUS STRIATUM; CORRELATION ANALYSIS; DEFLUORINATION; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG LIVER LEVEL; DRUG METABOLISM; DRUG MUSCLE LEVEL; DRUG SCREENING; DRUG SELECTIVITY; FEMALE; HEMOCONCENTRATION; HIPPOCAMPUS; HYPOTHALAMUS; IN VITRO STUDY; IN VIVO STUDY; KIDNEY; LUNG; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PREMEDICATION; PRIORITY JOURNAL; RADIOACTIVITY; RAT; STATISTICAL SIGNIFICANCE; ANIMAL; ANTIBODY SPECIFICITY; BRAIN; CELL STRAIN; COMPARATIVE STUDY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; EVALUATION; FEASIBILITY STUDY; MALE; METABOLIC CLEARANCE RATE; METABOLISM; METHODOLOGY; PAPIO; PROTEIN BINDING; SCINTISCANNING; SPECIES DIFFERENCE; SPRAGUE DAWLEY RAT; SWINE; TISSUE DISTRIBUTION;

ANIMALS; BENZYLAMINES; BRAIN; CARRIER PROTEINS; FEASIBILITY STUDIES; FEMALE; LIGANDS; LLC-PK1 CELLS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; METABOLIC CLEARANCE RATE; NERVE TISSUE PROTEINS; ORGAN SPECIFICITY; PAPIO; PROTEIN BINDING; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SPECIES SPECIFICITY; SWINE; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 1542472726     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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