Docosahexaenoic acid supplementation of primary rat hippocampal neurons attenuates the neurotoxicity induced by aggregated amyloid beta protein42 and up-regulates cytoskeletal protein expression

Journal of Nutritional Biochemistry

Volumn 21, Issue 4, 2010, Pages 345-350

  Wang, Pao Yuan ^a   Chen, Jen Jui ^a   Su, Hui Min ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Alzheimer's disease; Amyloid beta peptide; Cytoskeleton; Docosahexaenoic acid; Hippocampus; Neuron protection

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; DOCOSAHEXAENOIC ACID; HLA B27 ANTIGEN; TUBULIN; TYROSINE;

ACETYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSKELETON; DIET SUPPLEMENTATION; EMBRYO; FEMALE; HIPPOCAMPUS; NERVE CELL CULTURE; NEUROTOXICITY; NONHUMAN; PROTEIN EXPRESSION; RAT; UPREGULATION;

ACETYLATION; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CYTOSKELETAL PROTEINS; DOCOSAHEXAENOIC ACIDS; FATTY ACIDS; HIPPOCAMPUS; NEURONS; NEUROPROTECTIVE AGENTS; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; TUBULIN; UP-REGULATION;

RATTUS;

EID: 77649272657     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2009.01.012     Document Type: Article

References (56)

1. Annaert W., and De Strooper B. A cell biological perspective on Alzheimer's disease. Annu Rev Cell Dev Biol 18 (2002) 25-51
2. Glenner G.G., and Wong C.W. Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun 1203 (1984) 885-890
3. Mulder C., Scheltens P., Visser J.J., van Kamp G.J., and Schutgens R.B. Genetic and biochemical markers for Alzheimer's disease: recent developments. Ann Clin Biochem 37 Pt 5 (2000) 593-607
4. Jarrett J.T., Berger E.P., and Lansbury Jr. P.T. The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry 3218 (1993) 4693-4697
5. Selkoe D.J. Alzheimer's disease: genes, proteins, and therapy. Physiol Rev 812 (2001) 741-766
6. Takahashi R.H., Almeida C.G., Kearney P.F., Yu F., Lin M.T., Milner T.A., et al. Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain. J Neurosci 2414 (2004) 3592-3599
7. Fedorova I., and Salem Jr. N. Omega-3 fatty acids and rodent behavior. Prostaglandins leukotrienes, and essential fatty acids 754-5 (2006) 271-289
8. Innis S.M. Essential fatty acids in growth and development. Prog Lipid Res 301 (1991) 39-103
9. Sastry P.S. Lipids of nervous tissue: composition and metabolism. Prog Lipid Rese 242 (1985) 69-176
10. Martinez M. Tissue levels of polyunsaturated fatty acids during early human development. J Pediatr 1204 Pt 2 (1992) S129-S138
11. Martinez M. Polyunsaturated fatty acids in the developing human brain, erythrocytes and plasma in peroxisomal disease: therapeutic implications. J Inherit Metab Dis 18 Suppl 1 (1995) 61-75
12. Green P., Glozman S., Kamensky B., and Yavin E. Developmental changes in rat brain membrane lipids and fatty acids. The preferential prenatal accumulation of docosahexaenoic acid. J Lipid Res. 405 (1999) 960-966
13. Dobbing J., and Sands J. Comparative aspects of the brain growth spurt. Early Hum Dev 31 (1979) 79-83
14. Delion S., Chalon S., Guilloteau D., Lejeune B., Besnard J.C., and Durand G. Age-related changes in phospholipid fatty acid composition and monoaminergic neurotransmission in the hippocampus of rats fed a balanced or an n-3 polyunsaturated fatty acid-deficient diet. J Lipid Res 384 (1997) 680-689
15. Favrelere S., Stadelmann-Ingrand S., Huguet F., De Javel D., Piriou A., Tallineau C., et al. Age-related changes in ethanolamine glycerophospholipid fatty acid levels in rat frontal cortex and hippocampus. Neurobiol Aging 215 (2000) 653-660
16. Lukiw W.J., Cui J.G., Marcheselli V.L., Bodker M., Botkjaer A., Gotlinger K., et al. A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease. J Clin Invest 11510 (2005) 2774-2783
17. Prasad M.R., Lovell M.A., Yatin M., Dhillon H., and Markesbery W.R. Regional membrane phospholipid alterations in Alzheimer's disease. Neurochem Res 231 (1998) 81-88
18. Soderberg M., Edlund C., Kristensson K., and Dallner G. Fatty acid composition of brain phospholipids in aging and in Alzheimer's disease. Lipids 266 (1991) 421-425
19. Skinner E.R., Watt C., Besson J.A., and Best P.V. Differences in the fatty acid composition of the grey and white matter of different regions of the brains of patients with Alzheimer's disease and control subjects. Brain 116 Pt 3 (1993) 717-725
20. Guan Z.Z., Soderberg M., Sindelar P., and Edlund C. Content and fatty acid composition of cardiolipin in the brain of patients with Alzheimer's disease. Neurochem Int 253 (1994) 295-300
21. Chung W.L., Chen J.J., and Su H.M. Fish oil supplementation of control and (n-3) fatty acid-deficient male rats enhances reference and working memory performance and increases brain regional docosahexaenoic acid levels. J Nutr 138 (2008) 1165-1171
22. Calon F., Lim G.P., Yang F., Morihara T., Teter B., Ubeda O., et al. Docosahexaenoic Acid protects from dendritic pathology in an Alzheimer's disease mouse model. Neuron 435 (2004) 633-645
23. Hashimoto M., Hossain S., Shimada T., Sugioka K., Yamasaki H., Fujii Y., et al. Docosahexaenoic acid provides protection from impairment of learning ability in Alzheimer's disease model rats. J Neurochem 815 (2002) 1084-1091
24. Hashimoto M., Tanabe Y., Fujii Y., Kikuta T., Shibata H., and Shido O. Chronic administration of docosahexaenoic acid ameliorates the impairment of spatial cognition learning ability in amyloid beta-infused rats. J Nutr 1353 (2005) 549-555
25. Gamoh S., Hashimoto M., Hossain S., and Masumura S. Chronic administration of docosahexaenoic acid improves the performance of radial arm maze task in aged rats. Clin Exp Pharmacol Physiol 284 (2001) 266-270
26. Morris M.C., Evans D.A., Bienias J.L., Tangney C.C., Bennett D.A., Wilson R.S., et al. Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Arch Neurol 607 (2003) 940-946
27. van Gelder B.M., Tijhuis M., Kalmijn S., and Kromhout D. Fish consumption, n-3 fatty acids, and subsequent 5-y cognitive decline in elderly men: the Zutphen Elderly Study. Am J Clin Nutr 854 (2007) 1142-1147
28. Beydoun M.A., Kaufman J.S., Satia J.A., Rosamond W., and Folsom A.R. Plasma n-3 fatty acids and the risk of cognitive decline in older adults: the Atherosclerosis Risk in Communities Study. Am J Clin Nutr 854 (2007) 1103-1111
29. Florent S., Malaplate-Armand C., Youssef I., Kriem B., Koziel V., Escanye M.C., et al. Docosahexaenoic acid prevents neuronal apoptosis induced by soluble amyloid-beta oligomers. J Neurochem 962 (2006) 385-395
30. Kim H.Y., Akbar M., Lau A., and Edsall L. Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect. J Biol Chem 27545 (2000) 35215-35223
31. Lauritzen I., Blondeau N., Heurteaux C., Widmann C., Romey G., and Lazdunski M. Polyunsaturated fatty acids are potent neuroprotectors. EMBO J 198 (2000) 1784-1793
32. Akbar M., and Kim H.Y. Protective effects of docosahexaenoic acid in staurosporine-induced apoptosis: involvement of phosphatidylinositol-3 kinase pathway. J Neurochem 823 (2002) 655-665
33. Sponne I., Fifre A., Drouet B., Klein C., Koziel V., Pincon-Raymond M., et al. Apoptotic neuronal cell death induced by the non-fibrillar amyloid-beta peptide proceeds through an early reactive oxygen species-dependent cytoskeleton perturbation. J Biol Chem 2785 (2003) 3437-3445
34. Fifre A., Sponne I., Koziel V., Kriem B., Yen Potin F.T., Bihain B.E., et al. Microtubule-associated protein MAP1A, MAP1B, and MAP2 proteolysis during soluble amyloid beta-peptide-induced neuronal apoptosis. Synergistic involvement of calpain and caspase-3. J Biol Chem 2811 (2006) 229-240
35. Zou K., Kim D., Kakio A., Byun K., Gong J.S., Kim J., et al. Amyloid beta-protein (Abeta)1-40 protects neurons from damage induced by Abeta1-42 in culture and in rat brain. J Neurochem 873 (2003) 609-619
36. Lorenzo A., and Yankner B.A. Beta-amyloid neurotoxicity requires fibril formation and is inhibited by Congo red. Proc Natl Acad Sci U S A 9125 (1994) 12243-12247
37. Goslin R., Asmussen H., and Banker G. Rat hippocampal neuron in low density culture. In: Banker G., and Goslin K. (Eds). Culturing nerve cells. 2nd ed. (1998), The MIT Press, Cambridge, MA 309-370
38. Brewer G.J., Torricelli J.R., Evege E.K., and Price P.J. Optimized survival of hippocampal neurons in B27-supplemented neurobasal, a new serum-free medium combination. J Neurosci Res 355 (1993) 567-576
39. Kaduce T.L., Chen Y., Hell J.W., and Spector A.A. Docosahexaenoic acid synthesis from n-3 fatty acid precursors in rat hippocampal neurons. J Neurochem (2008)
40. Heredia L., Lin R., Vigo F.S., Kedikian G., Busciglio J., and Lorenzo A. Deposition of amyloid fibrils promotes cell-surface accumulation of amyloid beta precursor protein. Neurobiol Dis 163 (2004) 617-629
41. Price P.J., and Brewer G.J. Serum-free media for neural cell cultures: adult and embryonic. In: Fedoroff S., and Richardson A. (Eds). Protocols for Neural Cell Culture. 3rd ed. (2001), Humana Press, Totowa (NJ) 255-264
42. Zou K., Gong J.S., Yanagisawa K., and Michikawa M. A novel function of monomeric amyloid beta-protein serving as an antioxidant molecule against metal-induced oxidative damage. J Neurosci 2212 (2002) 4833-4841
43. Dotti C.G., Sullivan C.A., and Banker G.A. The establishment of polarity by hippocampal neurons in culture. J Neurosci 84 (1988) 1454-1468
44. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 651-2 (1983) 55-63
45. Bligh E.G., and Dyer W.J. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 378 (1959) 911-917
46. Akbar M., Calderon F., Wen Z., and Kim H.Y. Docosahexaenoic acid: a positive modulator of Akt signaling in neuronal survival. Proc Natl Acad Sci U S A 10231 (2005) 10858-10863
47. Rotstein N.P., Politi L.E., German O.L., and Girotti R. Protective effect of docosahexaenoic acid on oxidative stress-induced apoptosis of retina photoreceptors. Invest Ophthalmol Visual Sci 445 (2003) 2252-2259
48. Rotstein N.P., Aveldano M.I., Barrantes F.J., Roccamo A.M., and Politi L.E. Apoptosis of retinal photoreceptors during development in vitro: protective effect of docosahexaenoic acid. J Neurochem 692 (1997) 504-513
49. Calderon F., and Kim H.Y. Docosahexaenoic acid promotes neurite growth in hippocampal neurons. J Neurochem 904 (2004) 979-988
50. Wang X., Zhao X., Mao Z.Y., Wang X.M., and Liu Z.L. Neuroprotective effect of docosahexaenoic acid on glutamate-induced cytotoxicity in rat hippocampal cultures. Neuroreport 1418 (2003) 2457-2461
51. Yankner B.A., Duffy L.K., and Kirschner D.A. Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides. Science (New York, NY) 2504978 (1990) 279-282
52. Contreras M.A., Greiner R.S., Chang M.C., Myers C.S., Salem Jr. N., and Rapoport S.I. Nutritional deprivation of alpha-linolenic acid decreases but does not abolish turnover and availability of unacylated docosahexaenoic acid and docosahexaenoyl-CoA in rat brain. J Neurochem 756 (2000) 2392-2400
53. Ahmad A., Moriguchi T., and Salem N. Decrease in neuron size in docosahexaenoic acid-deficient brain. Pediatr Neurol 263 (2002) 210-218
54. Diau G.Y., Hsieh A.T., Sarkadi-Nagy E.A., Wijendran V., Nathanielsz P.W., and Brenna J.T. The influence of long chain polyunsaturate supplementation on docosahexaenoic acid and arachidonic acid in baboon neonate central nervous system. BMC Med 3 (2005) 11
55. Cao D., Xue R., Xu J., and Liu Z. Effects of docosahexaenoic acid on the survival and neurite outgrowth of rat cortical neurons in primary cultures. J Nutr Biochem 169 (2005) 538-546
56. Ikemoto A., Nitta A., Furukawa S., Ohishi M., Nakamura A., Fujii Y., et al. Dietary n-3 fatty acid deficiency decreases nerve growth factor content in rat hippocampus. Neurosci Lett 2852 (2000) 99-102