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Volumn 163, Issue 4, 1999, Pages 2028-2040

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; IMMUNOGLOBULIN HEAVY CHAIN; IONOMYCIN; LIPOPOLYSACCHARIDE; PHORBOL 13 ACETATE 12 MYRISTATE; PLASMID DNA; TRANSFORMING GROWTH FACTOR BETA;

EID: 0033566999     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (21)

References (62)
  • 1
    • 0024435039 scopus 로고
    • Molecular aspects of heavy-chain class switching
    • Gritzmacher, C. A. 1989. Molecular aspects of heavy-chain class switching. Crit. Rev. Immunol. 9:173.
    • (1989) Crit. Rev. Immunol. , vol.9 , pp. 173
    • Gritzmacher, C.A.1
  • 3
    • 0024330616 scopus 로고
    • A B-cell-specific nuclear protein that binds to DNA sites 5′ to immunoglobulin Sα tandem repeats is regulated during differentiation
    • Waters, S. H., K. U. Saikh, and J. Stavnezer. 1989. A B-cell-specific nuclear protein that binds to DNA sites 5′ to immunoglobulin Sα tandem repeats is regulated during differentiation. Mol. Cell. Biol. 9:5594.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 5594
    • Waters, S.H.1    Saikh, K.U.2    Stavnezer, J.3
  • 4
    • 0025215091 scopus 로고
    • Detection of an immunoglobulin switch region-specific DNA binding protein in mitogen-stimulated mouse splenic B cells
    • Wuerffel, R. A., A. T. Nathan, and A. L. Kenter. 1990. Detection of an immunoglobulin switch region-specific DNA binding protein in mitogen-stimulated mouse splenic B cells. Mol. Cell. Biol. 10:1714.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 1714
    • Wuerffel, R.A.1    Nathan, A.T.2    Kenter, A.L.3
  • 5
    • 0026770992 scopus 로고
    • Switch recombination breakpoints are strictly correlated with DNA recognition motifs for immunoglobulin Sγ3 DNA-binding proteins
    • Wuerffel, R., C. E. Jamieson, L. Morgan, G. V. Merkulov, R. Sen, and A. L. Kenter. 1992. Switch recombination breakpoints are strictly correlated with DNA recognition motifs for immunoglobulin Sγ3 DNA-binding proteins. J. Exp. Med. 176:339.
    • (1992) J. Exp. Med. , vol.176 , pp. 339
    • Wuerffel, R.1    Jamieson, C.E.2    Morgan, L.3    Merkulov, G.V.4    Sen, R.5    Kenter, A.L.6
  • 6
    • 0025833980 scopus 로고
    • LR1, a lipopolysaccharide-responsive factor with binding sites in the immunoglobulin switch regions and heavy-chain enhancer
    • Williams, M., and N. Maizels. 1991. LR1, a lipopolysaccharide-responsive factor with binding sites in the immunoglobulin switch regions and heavy-chain enhancer. Genes Dev. 5:2353.
    • (1991) Genes Dev. , vol.5 , pp. 2353
    • Williams, M.1    Maizels, N.2
  • 7
    • 0026514486 scopus 로고
    • A nuclear DNA-binding protein expressed during early stages of B cell differentiation interacts with diverse segments within and 3′ of the Ig H chain gene cluster
    • Liao, F., S. L. Giannini, and B. Birshtein. 1992. A nuclear DNA-binding protein expressed during early stages of B cell differentiation interacts with diverse segments within and 3′ of the Ig H chain gene cluster. J. Immunol. 148:2909.
    • (1992) J. Immunol. , vol.148 , pp. 2909
    • Liao, F.1    Giannini, S.L.2    Birshtein, B.3
  • 8
    • 0026638191 scopus 로고
    • Properties of B cell stage specific and ubiquitous factors binding to immunoglobulin heavy chain gene switch regions
    • Xu, L., M. G. Kim, and K. B. Marcu. 1992. Properties of B cell stage specific and ubiquitous factors binding to immunoglobulin heavy chain gene switch regions. Int. Immunol. 4:875.
    • (1992) Int. Immunol. , vol.4 , pp. 875
    • Xu, L.1    Kim, M.G.2    Marcu, K.B.3
  • 9
    • 0027424999 scopus 로고
    • Purification and properties of LR1, an inducible DNA binding protein from mammalian B lymphocytes
    • Williams, M., L. A. Hanakahi, and N. Maizels. 1993. Purification and properties of LR1, an inducible DNA binding protein from mammalian B lymphocytes. J. Biol. Chem. 268:13731.
    • (1993) J. Biol. Chem. , vol.268 , pp. 13731
    • Williams, M.1    Hanakahi, L.A.2    Maizels, N.3
  • 10
    • 0027519483 scopus 로고
    • Switch recombination breakpoints occur at nonrandom positions in the Sγ tandem repeat
    • Kenter, A. L., R. Wuerffel, R. Sen, C. E. Jamieson, and G. V. Merkulov. 1993. Switch recombination breakpoints occur at nonrandom positions in the Sγ tandem repeat. J. Immunol. 151:4718.
    • (1993) J. Immunol. , vol.151 , pp. 4718
    • Kenter, A.L.1    Wuerffel, R.2    Sen, R.3    Jamieson, C.E.4    Merkulov, G.V.5
  • 11
    • 0033534467 scopus 로고    scopus 로고
    • G4 DNA binding by LR1 and its subunits, nucleolin and hnRNP D, a role for G-G pairing in immunoglobulin switch recombination
    • Dempsey, L. A., Sun, H. Hanakahi, L. A., and Maizels, N. 1999. G4 DNA binding by LR1 and its subunits, nucleolin and hnRNP D, a role for G-G pairing in immunoglobulin switch recombination. J. Biol. Chem. 274:1066.
    • (1999) J. Biol. Chem. , vol.274 , pp. 1066
    • Dempsey, L.A.1    Sun, H.2    Hanakahi, L.A.3    Maizels, N.4
  • 12
    • 0030954401 scopus 로고    scopus 로고
    • Ig Sγ-specific DNA binding protein SNAP is related to the helix-loop-helix transcription factor E47
    • Ma, L., B. Hu, and A. L. Kenter. 1997. Ig Sγ-specific DNA binding protein SNAP is related to the helix-loop-helix transcription factor E47. Intern. Immunol. 9:1021.
    • (1997) Intern. Immunol. , vol.9 , pp. 1021
    • Ma, L.1    Hu, B.2    Kenter, A.L.3
  • 13
    • 0024511717 scopus 로고
    • Mutations, duplication, and deletion of recombined switch regions suggest a role for DNA replication in the immunoglobulin heavy-chain switch
    • Dunnick, W., M. Wilson, and J. Stavnezer. 1989. Mutations, duplication, and deletion of recombined switch regions suggest a role for DNA replication in the immunoglobulin heavy-chain switch. Mol. Cell. Biol. 9:1850.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 1850
    • Dunnick, W.1    Wilson, M.2    Stavnezer, J.3
  • 14
    • 0025070155 scopus 로고
    • Copy choice mechanism of immunoglobulin heavy chain switch recombination
    • Dunnick, W., and J. Stavnezer. 1990. Copy choice mechanism of immunoglobulin heavy chain switch recombination. Mol. Cell. Biol. 10:397.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 397
    • Dunnick, W.1    Stavnezer, J.2
  • 15
    • 0031278299 scopus 로고    scopus 로고
    • Ig Sγ3 DNA-specific double strand breaks are induced in mitogen-activated B cells and are implicated in switch recombination
    • Wuerffel, R. A., J. Du, R. J. Thompson, and A. L. Kenter. 1997. Ig Sγ3 DNA-specific double strand breaks are induced in mitogen-activated B cells and are implicated in switch recombination. J. Immunol. 159:4139.
    • (1997) J. Immunol. , vol.159 , pp. 4139
    • Wuerffel, R.A.1    Du, J.2    Thompson, R.J.3    Kenter, A.L.4
  • 16
    • 0030273141 scopus 로고    scopus 로고
    • The SCID but not the RAG-2 gene product is required for Sμ-Sε heavy chain class switching
    • Rolink, A., F. Melchers, and J. Andersson. 1996. The SCID but not the RAG-2 gene product is required for Sμ-Sε heavy chain class switching. Immunity 5:319.
    • (1996) Immunity , vol.5 , pp. 319
    • Rolink, A.1    Melchers, F.2    Andersson, J.3
  • 21
    • 0027245559 scopus 로고
    • V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair
    • Pergola, F., M. Z. Zdzienicka, and M. Lieber. 1993. V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair. Mol. Cell. Biol. 13:3464.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3464
    • Pergola, F.1    Zdzienicka, M.Z.2    Lieber, M.3
  • 22
    • 0027156278 scopus 로고
    • Impairment of V(D)J recombination in double-strand break repair mutants
    • Taccioli, G. E., G. Rathbun, E. Olz, T. Stamato, P. A. Jeggo, and F. W. Alt. 1993. Impairment of V(D)J recombination in double-strand break repair mutants. Science 260:207.
    • (1993) Science , vol.260 , pp. 207
    • Taccioli, G.E.1    Rathbun, G.2    Olz, E.3    Stamato, T.4    Jeggo, P.A.5    Alt, F.W.6
  • 23
    • 0022599997 scopus 로고
    • Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching
    • Stavnezer-Nordgren, J., and S. Sirlin. 1986. Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching. EMBO J. 5:95.
    • (1986) EMBO J. , vol.5 , pp. 95
    • Stavnezer-Nordgren, J.1    Sirlin, S.2
  • 24
    • 0023889066 scopus 로고
    • Mitogen-and IL-4-regulated expression of germline Igγ2b transcripts: Evidence for directed heavy chain class switching
    • Lutzker, S., P. Rothman, R. Pollock, R. Coffman, and F. W. Alt. 1988. Mitogen-and IL-4-regulated expression of germline Igγ2b transcripts: evidence for directed heavy chain class switching. Cell. 53:177.
    • (1988) Cell , vol.53 , pp. 177
    • Lutzker, S.1    Rothman, P.2    Pollock, R.3    Coffman, R.4    Alt, F.W.5
  • 25
    • 0025347840 scopus 로고
    • Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination
    • Severinson, E., C. Fernandez, and J. Stavnezer. 1990. Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination. Eur. J. Immunol. 20:1079.
    • (1990) Eur. J. Immunol. , vol.20 , pp. 1079
    • Severinson, E.1    Fernandez, C.2    Stavnezer, J.3
  • 26
    • 0030022218 scopus 로고    scopus 로고
    • Antibody class switching
    • Stavnezer, J. 1996. Antibody class switching. Adv. Immunol. 61:79.
    • (1996) Adv. Immunol. , vol.61 , pp. 79
    • Stavnezer, J.1
  • 27
    • 0027372064 scopus 로고
    • Mechanism and regulation of immunoglobulin isotype switching
    • Coffman, R. L., D. A. Lebman, and P. B. Rothman. 1993. Mechanism and regulation of immunoglobulin isotype switching. Adv. Immunol. 54:229.
    • (1993) Adv. Immunol. , vol.54 , pp. 229
    • Coffman, R.L.1    Lebman, D.A.2    Rothman, P.B.3
  • 28
    • 0029931447 scopus 로고    scopus 로고
    • Immunoglobulin class switching
    • Stavnezer, J. 1996. Immunoglobulin class switching. Curr. Opin. Immunol. 8:199.
    • (1996) Curr. Opin. Immunol. , vol.8 , pp. 199
    • Stavnezer, J.1
  • 29
    • 0027417869 scopus 로고
    • Shutdown of class switch recombination by deletion of a switch region control element
    • Jung, S., K. Rajewsky, and A. Radbruch. 1993. Shutdown of class switch recombination by deletion of a switch region control element. Science 259:984.
    • (1993) Science , vol.259 , pp. 984
    • Jung, S.1    Rajewsky, K.2    Radbruch, A.3
  • 30
    • 0027273019 scopus 로고
    • A selective defect in IgG2b switching as a result of targeted mutation of the Iγ2b promoter and exon
    • Zhang, J., A. Bottaro, S. Li, V. Stewart, and F. W. Alt. 1993. A selective defect in IgG2b switching as a result of targeted mutation of the Iγ2b promoter and exon. EMBO J. 12:3529.
    • (1993) EMBO J. , vol.12 , pp. 3529
    • Zhang, J.1    Bottaro, A.2    Li, S.3    Stewart, V.4    Alt, F.W.5
  • 31
    • 0027952630 scopus 로고
    • 1 region transcription (per se) promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process
    • Bottaro, A., R. Lansford, L. Xu, J. Zhang, P. Rothman, and F. Alt. 1994.1 region transcription (per se) promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process. EMBO J. 13:665.
    • (1994) EMBO J. , vol.13 , pp. 665
    • Bottaro, A.1    Lansford, R.2    Xu, L.3    Zhang, J.4    Rothman, P.5    Alt, F.6
  • 32
    • 0028968667 scopus 로고
    • Switch transcripts in immunoglobulin class switching
    • Lorenz, M., S. Jung, and A. Radbruch. 1995. Switch transcripts in immunoglobulin class switching. Science 267:1825.
    • (1995) Science , vol.267 , pp. 1825
    • Lorenz, M.1    Jung, S.2    Radbruch, A.3
  • 33
    • 0026575837 scopus 로고
    • Transcriptional regulatory elements stimulate recombination in extrachromosomal substrates carrying immunoglobulin switch-region sequences
    • Leung, H., and N. Maizels. 1992. Transcriptional regulatory elements stimulate recombination in extrachromosomal substrates carrying immunoglobulin switch-region sequences. Proc. Natl. Acad Sci. USA 89:4154.
    • (1992) Proc. Natl. Acad Sci. USA , vol.89 , pp. 4154
    • Leung, H.1    Maizels, N.2
  • 34
    • 0028040264 scopus 로고
    • Regulation and targeting of recombination in extrachromosomal substrates carrying immunoglobulin switch region sequences
    • Leung, H., and N. Maizels. 1994. Regulation and targeting of recombination in extrachromosomal substrates carrying immunoglobulin switch region sequences. Mol. Cell. Biol. 14:1450.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1450
    • Leung, H.1    Maizels, N.2
  • 35
    • 0029046127 scopus 로고
    • Strand specificity in the transcriptional targeting of recombination at immunoglobulin switch sequences
    • Daniels, G. A., and M. R. Lieber. 1995. Strand specificity in the transcriptional targeting of recombination at immunoglobulin switch sequences. Proc. Natl. Acad. Sci. USA 92:5625.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5625
    • Daniels, G.A.1    Lieber, M.R.2
  • 36
    • 0029598833 scopus 로고
    • RNA:DNA complex formation upon transcription of immunoglobulin switch regions: Implications for the mechanism and regulation of class switch recombination
    • Daniels, G. A., and M. R. Lieber. 1995. RNA:DNA complex formation upon transcription of immunoglobulin switch regions: implications for the mechanism and regulation of class switch recombination. Nucleic Acids Res. 23:5006.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 5006
    • Daniels, G.A.1    Lieber, M.R.2
  • 37
    • 0029992148 scopus 로고    scopus 로고
    • Asymmetric mutation around the recombination break point of immunoglobulin class switch sequences on extrachromosomal substrates
    • Li, J., Daniels, G.A., and Lieber, M.R. 1996. Asymmetric mutation around the recombination break point of immunoglobulin class switch sequences on extrachromosomal substrates. Nucleic Acids Res. 24:2104.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 2104
    • Li, J.1    Daniels, G.A.2    Lieber, M.R.3
  • 38
    • 0023302575 scopus 로고
    • Immunoglobulin heavy chain switch region recombination within a retroviral vector in murine pre-B cells
    • Ott, D. E., F. W. Alt, and K. B. Marcu. 1987. Immunoglobulin heavy chain switch region recombination within a retroviral vector in murine pre-B cells. EMBO J. 6:577.
    • (1987) EMBO J. , vol.6 , pp. 577
    • Ott, D.E.1    Alt, F.W.2    Marcu, K.B.3
  • 39
    • 0024379021 scopus 로고
    • Molecular requirements for immunoglobulin heavy chain constant region gene switch-recombination revealed with switch-substrate retroviruses
    • Ott, D. E., and K. B. Marcu. 1989. Molecular requirements for immunoglobulin heavy chain constant region gene switch-recombination revealed with switch-substrate retroviruses. Int. Immunol. 1:582.
    • (1989) Int. Immunol. , vol.1 , pp. 582
    • Ott, D.E.1    Marcu, K.B.2
  • 40
    • 0031266608 scopus 로고    scopus 로고
    • Antibody class switch recombinase activity is B cell stage specific and functions stochastically in the absence of "targeted accessibility" control
    • Ballantyne, J., D. L. Henry, and K. B. Marcu. 1997. Antibody class switch recombinase activity is B cell stage specific and functions stochastically in the absence of "targeted accessibility" control. Int. Immunol. 9:963.
    • (1997) Int. Immunol. , vol.9 , pp. 963
    • Ballantyne, J.1    Henry, D.L.2    Marcu, K.B.3
  • 41
    • 0032145488 scopus 로고    scopus 로고
    • Efficient recombination of a switch substrate retrovector in CD40-activated B lymphoctyes: Implications for the control of CH gene switch recombination
    • Ballantyne, J., D. L. Henry, J. R. Muller, F. Briere, C. M. Snapper, M. Kehry, and K. B. Marcu. 1998. Efficient recombination of a switch substrate retrovector in CD40-activated B lymphoctyes: implications for the control of CH gene switch recombination. J. Immunol. 161:1336.
    • (1998) J. Immunol. , vol.161 , pp. 1336
    • Ballantyne, J.1    Henry, D.L.2    Muller, J.R.3    Briere, F.4    Snapper, C.M.5    Kehry, M.6    Marcu, K.B.7
  • 42
    • 0021963170 scopus 로고
    • Induction of immunoglobulin isotype switching in cultured 1.29 B lymphoma cells: Characterization of the accompanying rearrangements of heavy chain genes
    • Stavnezer, J., S. Sirlin, and J. Abbott. 1985. Induction of immunoglobulin isotype switching in cultured 1.29 B lymphoma cells: characterization of the accompanying rearrangements of heavy chain genes. J. Exp. Med. 161:577.
    • (1985) J. Exp. Med. , vol.161 , pp. 577
    • Stavnezer, J.1    Sirlin, S.2    Abbott, J.3
  • 43
    • 0026334161 scopus 로고
    • Effect of cylokines on switching to IgA and a germline transcripts in the B lymphoma 1.29μ: Transforming growth factor-β activates transcription of the unrearranged Cα gene
    • Shockett, P., and J. Stavnezer. 1991. Effect of cylokines on switching to IgA and a germline transcripts in the B lymphoma 1.29μ: transforming growth factor-β activates transcription of the unrearranged Cα gene. J. Immunol. 147: 4374-4383.
    • (1991) J. Immunol. , vol.147 , pp. 4374-4383
    • Shockett, P.1    Stavnezer, J.2
  • 44
    • 0027141893 scopus 로고
    • Inhibitors of poly(ADP-ribose) polymerase increase antibody class switching
    • Shockett, P., and J. Stavnezer. 1993. Inhibitors of poly(ADP-ribose) polymerase increase antibody class switching. J. Immunol. 151:6962.
    • (1993) J. Immunol. , vol.151 , pp. 6962
    • Shockett, P.1    Stavnezer, J.2
  • 45
    • 0024446350 scopus 로고
    • Transforming growth factor-β specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes
    • Coffman, R. L., D. A. Lebman, and B. Shrader. 1989. Transforming growth factor-β specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes. J. Exp. Med. 170:1039.
    • (1989) J. Exp. Med. , vol.170 , pp. 1039
    • Coffman, R.L.1    Lebman, D.A.2    Shrader, B.3
  • 47
    • 0028916191 scopus 로고
    • Novel in vitro model for high-rate IgA class switching
    • McIntyre, T. M., M. R. Kehry, and C. M. Snapper. 1995. Novel in vitro model for high-rate IgA class switching. J. Immunol. 154:3156.
    • (1995) J. Immunol. , vol.154 , pp. 3156
    • McIntyre, T.M.1    Kehry, M.R.2    Snapper, C.M.3
  • 48
    • 0019211069 scopus 로고
    • 5′ flanking region of immunoglobulin heavy chain constant region genes displays length heterogeneity in germlines of inbred mouse strains
    • Marcu, K. B., J. Banerji, N. A. Penncavage, R. Lang, and N. Arnheim. 1980. 5′ flanking region of immunoglobulin heavy chain constant region genes displays length heterogeneity in germlines of inbred mouse strains. Cell 22:187.
    • (1980) Cell , vol.22 , pp. 187
    • Marcu, K.B.1    Banerji, J.2    Penncavage, N.A.3    Lang, R.4    Arnheim, N.5
  • 49
    • 0026698147 scopus 로고
    • Pax-5 encodes the transcription factor BASF and is expressed in B lymphocytes, the developing CNS, and adult testis
    • Adams, B., P. Dorfler, A. Aguzzi, Z. y. Kozmik, P. Urbanek, I. Maurer-Fogy, and M. Busslinger. 1992. Pax-5 encodes the transcription factor BASF and is expressed in B lymphocytes, the developing CNS, and adult testis. Genes Dev. 6:1589.
    • (1992) Genes Dev. , vol.6 , pp. 1589
    • Adams, B.1    Dorfler, P.2    Aguzzi, A.3    Kozmik, Z.Y.4    Urbanek, P.5    Maurer-Fogy, I.6    Busslinger, M.7
  • 50
    • 0023709349 scopus 로고
    • A retroviral expression vector containing murine immunoglobulin heavy chain promoter/enhancer
    • Blankenstein, T., E. Winter, and W. Muller. 1988. A retroviral expression vector containing murine immunoglobulin heavy chain promoter/enhancer. Nucleic Acids Res. 16:10939.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 10939
    • Blankenstein, T.1    Winter, E.2    Muller, W.3
  • 51
    • 0026649466 scopus 로고
    • Regulation of transcription of the germline Igα constant region gene by an ATF element and by novel transforming growth factor-β1-responsive elements
    • Lin, Y.-C. A., and J. Stavnezer. 1992. Regulation of transcription of the germline Igα constant region gene by an ATF element and by novel transforming growth factor-β1-responsive elements. J. Immunol. 149:2914.
    • (1992) J. Immunol. , vol.149 , pp. 2914
    • Lin, Y.-C.A.1    Stavnezer, J.2
  • 52
    • 0032530747 scopus 로고    scopus 로고
    • Over-expression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the 1.29μ B cell line
    • Qiu, G., and J. Stavnezer. 1998. Over-expression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the 1.29μ B cell line. J. Immunol. 161:2906.
    • (1998) J. Immunol. , vol.161 , pp. 2906
    • Qiu, G.1    Stavnezer, J.2
  • 53
    • 0024598146 scopus 로고
    • Fast and sensitive multiple sequence alignments on a microcomputer
    • Higgins, D. G., and P. M. Sharp. 1989. Fast and sensitive multiple sequence alignments on a microcomputer. Comput. Appl. Biosci. 5:151.
    • (1989) Comput. Appl. Biosci. , vol.5 , pp. 151
    • Higgins, D.G.1    Sharp, P.M.2
  • 56
    • 0030610995 scopus 로고    scopus 로고
    • Analysis of immunoglobulin Sγ3 recombination breakpoints by PCR: Implications for the mechanism of isotype switching
    • Du, J., A. Shanmugam, and A. L. Kenter. 1997. Analysis of immunoglobulin Sγ3 recombination breakpoints by PCR: implications for the mechanism of isotype switching. Nucleic Acids Res. 25:3066.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 3066
    • Du, J.1    Shanmugam, A.2    Kenter, A.L.3
  • 57
    • 0020336284 scopus 로고
    • Spontaneous immunoglobulin class switching in myeloma and hybridoma cell lines differs from physiological class switching
    • Sablitsky, F., A. Radbruch, and K. Rajewsky. 1982. Spontaneous immunoglobulin class switching in myeloma and hybridoma cell lines differs from physiological class switching. Immunol. Rev. 67:59.
    • (1982) Immunol. Rev. , vol.67 , pp. 59
    • Sablitsky, F.1    Radbruch, A.2    Rajewsky, K.3
  • 58
    • 0022976432 scopus 로고
    • Nonhomologous recombination in mammalian cells: Role for short sequence homologies in the joining reaction
    • Roth, D. B., and J. H. Wilson. 1986. Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction. Mol. Cell. Biol. 6:4295.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 4295
    • Roth, D.B.1    Wilson, J.H.2
  • 59
    • 0028048275 scopus 로고
    • The mechanism of V(D)J joining: Lessons from molecular, immunological, and comparative analyses
    • Lewis, S. M. 1994. The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses. Adv. Immunol. 56:27.
    • (1994) Adv. Immunol. , vol.56 , pp. 27
    • Lewis, S.M.1
  • 60
    • 0028352067 scopus 로고
    • Illegitimate recombination in Xenopus: Characterization of end-joined junctions
    • Lehman, C. W., J. K. Trautman, and D. Carroll. 1994. Illegitimate recombination in Xenopus: characterization of end-joined junctions. Nucleic Acids Res. 22:34.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 34
    • Lehman, C.W.1    Trautman, J.K.2    Carroll, D.3
  • 61
    • 0029894165 scopus 로고    scopus 로고
    • Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro
    • Stanhope-Baker, P., K. M. Hudson, A. L. Shaffer, A. Constantinescu, and M. S. Schlissel. 1996. Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro. Cell 85:887.
    • (1996) Cell , vol.85 , pp. 887
    • Stanhope-Baker, P.1    Hudson, K.M.2    Shaffer, A.L.3    Constantinescu, A.4    Schlissel, M.S.5
  • 62
    • 0032428658 scopus 로고    scopus 로고
    • Target specificity of immunoglobulin class switch recombination is not determined by nucleotide sequences of S regions
    • Kinoshita, K., J. Tashiro, S. Tomita, C.-G. Lee, and T. Honjo. 1998. Target specificity of immunoglobulin class switch recombination is not determined by nucleotide sequences of S regions. Immunity 9:849.
    • (1998) Immunity , vol.9 , pp. 849
    • Kinoshita, K.1    Tashiro, J.2    Tomita, S.3    Lee, C.-G.4    Honjo, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.