-
1
-
-
33846004815
-
Five years of progress on cyclin-dependent kinases and other cellular proteins as potential targets for antiviral drugs
-
Schang LM, St Vincent MR, Lacasse JJ. Five years of progress on cyclin-dependent kinases and other cellular proteins as potential targets for antiviral drugs. Antivir Chem Chemother 2006; 17:293-320.
-
(2006)
Antivir Chem Chemother
, vol.17
, pp. 293-320
-
-
Schang, L.M.1
St Vincent, M.R.2
Lacasse, J.J.3
-
2
-
-
0026721068
-
A family of human cdc2-related protein kinases
-
Meyerson M, Enders GH, Wu CL, et al. A family of human cdc2-related protein kinases. EMBO J 1992; 11:2909-2917.
-
(1992)
EMBO J
, vol.11
, pp. 2909-2917
-
-
Meyerson, M.1
Enders, G.H.2
Wu, C.L.3
-
3
-
-
0035865203
-
Can sequencing shed light on cell cycling?
-
Murray AW, Marks D. Can sequencing shed light on cell cycling? Nature 2001; 409:844-846.
-
(2001)
Nature
, vol.409
, pp. 844-846
-
-
Murray, A.W.1
Marks, D.2
-
4
-
-
0037032835
-
The protein kinase complement of the human genome
-
Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S. The protein kinase complement of the human genome. Science 2002; 298:1912- 1934.
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
6
-
-
0034721195
-
Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles
-
Arris CE, Boyle FT, Calvert AH, et al. Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles. J Med Chem 2000; 43:2797-2804.
-
(2000)
J Med Chem
, vol.43
, pp. 2797-2804
-
-
Arris, C.E.1
Boyle, F.T.2
Calvert, A.H.3
-
7
-
-
0031028163
-
Inhibition of cyclin-dependent kinases by purine analogues: Crystal structure of human cdk2 complexed with roscovitine
-
De Azevedo WF, Leclerc S, Meijer L, et al. Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine. Eur J Biochem 1997; 243:518-526.
-
(1997)
Eur J Biochem
, vol.243
, pp. 518-526
-
-
De Azevedo, W.F.1
Leclerc, S.2
Meijer, L.3
-
8
-
-
0028093182
-
Inhibition of cyclindependent kinases by purine analogues
-
Vesely J, Havlicek L, Strnad M, et al. Inhibition of cyclindependent kinases by purine analogues. Eur J Biochem 1994; 224:771-786.
-
(1994)
Eur J Biochem
, vol.224
, pp. 771-786
-
-
Vesely, J.1
Havlicek, L.2
Strnad, M.3
-
9
-
-
0028176485
-
Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275
-
Losiewicz MD, Carlson BA, Kaur G, Sausville EA, Worland PJ. Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275. Biochem Biophys Res Commun 1994; 201:589-595.
-
(1994)
Biochem Biophys Res Commun
, vol.201
, pp. 589-595
-
-
Losiewicz, M.D.1
Carlson, B.A.2
Kaur, G.3
Sausville, E.A.4
Worland, P.J.5
-
10
-
-
0031037714
-
Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5
-
Meijer L, Borgne A, Mulner O, et al. Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5. Eur J Biochem 1997; 243:527-536.
-
(1997)
Eur J Biochem
, vol.243
, pp. 527-536
-
-
Meijer, L.1
Borgne, A.2
Mulner, O.3
-
11
-
-
0037131730
-
Synthesis and biological activity of olomoucine II
-
Kryštof V, Lenobel R, Havlicek L, Kuzma M, Strnad M. Synthesis and biological activity of olomoucine II. Bioorg Med Chem Lett 2002; 12:3283-3286.
-
(2002)
Bioorg Med Chem Lett
, vol.12
, pp. 3283-3286
-
-
Kryštof, V.1
Lenobel, R.2
Havlicek, L.3
Kuzma, M.4
Strnad, M.5
-
12
-
-
23844525170
-
Antiproliferative activity of olomoucine II, a novel 2,6,9-trisubstituted purine cyclin-dependent kinase inhibitor
-
Kryštof V, McNae IW, Walkinshaw MD, et al. Antiproliferative activity of olomoucine II, a novel 2,6,9-trisubstituted purine cyclin-dependent kinase inhibitor. Cell Mol Life Sci 2005; 62:1763-1771.
-
(2005)
Cell Mol Life Sci
, vol.62
, pp. 1763-1771
-
-
Kryštof, V.1
McNae, I.W.2
Walkinshaw, M.D.3
-
13
-
-
0034812298
-
The cyclin-dependent kinase inhibitor roscovitine inhibits RNA synthesis and triggers nuclear accumulation of p53 that is unmodified at Ser15 and Lys382
-
Ljungman M, Paulsen MT. The cyclin-dependent kinase inhibitor roscovitine inhibits RNA synthesis and triggers nuclear accumulation of p53 that is unmodified at Ser15 and Lys382. Mol Pharmacol 2001; 60:785-789.
-
(2001)
Mol Pharmacol
, vol.60
, pp. 785-789
-
-
Ljungman, M.1
Paulsen, M.T.2
-
14
-
-
4143120023
-
Roscovitine inhibits activation of promoters in herpes simplex virus type 1 genomes independently of promoter-specific factors
-
Diwan P, Lacasse JJ, Schang LM. Roscovitine inhibits activation of promoters in herpes simplex virus type 1 genomes independently of promoter-specific factors. J Virol 2004; 78:9352-9365.
-
(2004)
J Virol
, vol.78
, pp. 9352-9365
-
-
Diwan, P.1
Lacasse, J.J.2
Schang, L.M.3
-
15
-
-
0031009357
-
Inhibition of cellular Cdk2 activity blocks human cytomegalovirus replication
-
Bresnahan WA, Boldogh I, Chi P, Thompson EA, Albrecht T. Inhibition of cellular Cdk2 activity blocks human cytomegalovirus replication. Virology 1997; 231:239-247.
-
(1997)
Virology
, vol.231
, pp. 239-247
-
-
Bresnahan, W.A.1
Boldogh, I.2
Chi, P.3
Thompson, E.A.4
Albrecht, T.5
-
16
-
-
14444281157
-
P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro
-
Mancebo HS, Lee G, Flygare J, et al. P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro. Genes Dev 1997; 11:2633-2644.
-
(1997)
Genes Dev
, vol.11
, pp. 2633-2644
-
-
Mancebo, H.S.1
Lee, G.2
Flygare, J.3
-
17
-
-
0031746015
-
Requirement for cellular cyclin-dependent kinases in herpes simplex virus replication and transcription
-
Schang LM, Phillips J, Schaffer PA. Requirement for cellular cyclin-dependent kinases in herpes simplex virus replication and transcription. J Virol 1998; 72:5626-5637.
-
(1998)
J Virol
, vol.72
, pp. 5626-5637
-
-
Schang, L.M.1
Phillips, J.2
Schaffer, P.A.3
-
18
-
-
0036310685
-
Pharmacological cyclin-dependent kinase inhibitors inhibit replication of wild-type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus type 1 by targeting cellular, not viral, proteins
-
Schang LM, Bantly A, Knockaert M, et al. Pharmacological cyclin-dependent kinase inhibitors inhibit replication of wild-type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus type 1 by targeting cellular, not viral, proteins. J Virol 2002; 76:7874-7882.
-
(2002)
J Virol
, vol.76
, pp. 7874-7882
-
-
Schang, L.M.1
Bantly, A.2
Knockaert, M.3
-
19
-
-
0034910933
-
Inhibition of human immunodeficiency virus type 1 transcription by chemical cyclin-dependent kinase inhibitors
-
Wang D, de la Fuente C, Deng L, et al. Inhibition of human immunodeficiency virus type 1 transcription by chemical cyclin-dependent kinase inhibitors. J Virol 2001; 75:7266-7279.
-
(2001)
J Virol
, vol.75
, pp. 7266-7279
-
-
Wang, D.1
de la Fuente, C.2
Deng, L.3
-
20
-
-
0036686954
-
Inhibition of HTLV-1 transcription by cyclin dependent kinase inhibitors
-
Wang L, Deng L, Wu K, et al. Inhibition of HTLV-1 transcription by cyclin dependent kinase inhibitors. Mol Cell Biochem 2002; 237:137-153.
-
(2002)
Mol Cell Biochem
, vol.237
, pp. 137-153
-
-
Wang, L.1
Deng, L.2
Wu, K.3
-
21
-
-
0346365302
-
Inhibition of S-phase cyclin-dependent kinase activity blocks expression of Epstein-Barr virus immediate-early and early genes, preventing viral lytic replication
-
Kudoh A, Daikoku T, Sugaya Y, et al. Inhibition of S-phase cyclin-dependent kinase activity blocks expression of Epstein-Barr virus immediate-early and early genes, preventing viral lytic replication. J Virol 2004; 78:104-115.
-
(2004)
J Virol
, vol.78
, pp. 104-115
-
-
Kudoh, A.1
Daikoku, T.2
Sugaya, Y.3
-
22
-
-
0036147535
-
The cyclin-dependent kinase inhibitor roscovitine inhibits the transactivating activity and alters the posttranslational modification of herpes simplex virus type 1 ICP0
-
Davido DJ, Leib DA, Schaffer PA. The cyclin-dependent kinase inhibitor roscovitine inhibits the transactivating activity and alters the posttranslational modification of herpes simplex virus type 1 ICP0. J Virol 2002; 76:1077-1088.
-
(2002)
J Virol
, vol.76
, pp. 1077-1088
-
-
Davido, D.J.1
Leib, D.A.2
Schaffer, P.A.3
-
23
-
-
37349126983
-
Inhibition of the cyclin-dependent kinases at the beginning of human cytomegalovirus infection specifically alters the levels and localization of the RNA polymerase II carboxyl-terminal domain kinases cdk9 and cdk7 at the viral transcriptosome
-
Kapasi AJ, Spector DH. Inhibition of the cyclin-dependent kinases at the beginning of human cytomegalovirus infection specifically alters the levels and localization of the RNA polymerase II carboxyl-terminal domain kinases cdk9 and cdk7 at the viral transcriptosome. J Virol 2008; 82:394-407.
-
(2008)
J Virol
, vol.82
, pp. 394-407
-
-
Kapasi, A.J.1
Spector, D.H.2
-
24
-
-
0034665961
-
Flavopiridol inhibits P-TEFb and blocks HIV-1 replication
-
Chao SH, Fujinaga K, Marion JE, et al. Flavopiridol inhibits P-TEFb and blocks HIV-1 replication. J Biol Chem 2000; 275:28345-28348.
-
(2000)
J Biol Chem
, vol.275
, pp. 28345-28348
-
-
Chao, S.H.1
Fujinaga, K.2
Marion, J.E.3
-
25
-
-
0033053592
-
Transcription of herpes simplex virus immediate-early and early genes is inhibited by roscovitine, an inhibitor specific for cellular cyclin-dependent kinases
-
Schang LM, Rosenberg A, Schaffer PA. Transcription of herpes simplex virus immediate-early and early genes is inhibited by roscovitine, an inhibitor specific for cellular cyclin-dependent kinases. J Virol 1999; 73:2161-2172.
-
(1999)
J Virol
, vol.73
, pp. 2161-2172
-
-
Schang, L.M.1
Rosenberg, A.2
Schaffer, P.A.3
-
26
-
-
0033375469
-
Flavopiridol: The first cyclin-dependent kinase inhibitor in human clinical trials
-
Senderowicz AM. Flavopiridol: the first cyclin-dependent kinase inhibitor in human clinical trials. Invest New Drugs 1999; 17:313-320.
-
(1999)
Invest New Drugs
, vol.17
, pp. 313-320
-
-
Senderowicz, A.M.1
-
27
-
-
0029814850
-
Inhibition of herpes simplex virus type 1 immediate-early gene expression by alpha interferon is not VP16 specific
-
Nicholl MJ, Preston CM. Inhibition of herpes simplex virus type 1 immediate-early gene expression by alpha interferon is not VP16 specific. J Virol 1996; 70:6336-6339.
-
(1996)
J Virol
, vol.70
, pp. 6336-6339
-
-
Nicholl, M.J.1
Preston, C.M.2
-
28
-
-
0031029580
-
Induction of Cip/Kip and Ink4 cyclin dependent kinase inhibitors by interferon-α in hematopoietic cell lines
-
Sangfelt O, Erickson S, Einhorn S, Grander D. Induction of Cip/Kip and Ink4 cyclin dependent kinase inhibitors by interferon-α in hematopoietic cell lines. Oncogene 1997; 14:415-423.
-
(1997)
Oncogene
, vol.14
, pp. 415-423
-
-
Sangfelt, O.1
Erickson, S.2
Einhorn, S.3
Grander, D.4
-
29
-
-
0028978667
-
Cyclin A and Cdk2 kinase activity are suppressed by combined treatment with tumor necrosis factor-α and interferon-α
-
Satomoto K, Haisa M, Naomoto Y, Tanaka N, Orita K. Cyclin A and Cdk2 kinase activity are suppressed by combined treatment with tumor necrosis factor-α and interferon-α. Biochem Biophys Res Commun 1995; 213:1115-1121.
-
(1995)
Biochem Biophys Res Commun
, vol.213
, pp. 1115-1121
-
-
Satomoto, K.1
Haisa, M.2
Naomoto, Y.3
Tanaka, N.4
Orita, K.5
-
30
-
-
0032518668
-
Interferon-induces expression of cyclin-dependent kinaseinhibitors p21WAF1 and p27Kip1 that prevent activation of cyclin-dependent kinase by CDK-activating kinase (CAK)
-
Mandal M, Bandyopadhyay D, Goepfert TM, Kumar R. Interferon-induces expression of cyclin-dependent kinaseinhibitors p21WAF1 and p27Kip1 that prevent activation of cyclin-dependent kinase by CDK-activating kinase (CAK). Oncogene 1998; 16:217-225.
-
(1998)
Oncogene
, vol.16
, pp. 217-225
-
-
Mandal, M.1
Bandyopadhyay, D.2
Goepfert, T.M.3
Kumar, R.4
-
31
-
-
0031055563
-
Cytokinin-derived cyclin-dependent kinase inhibitors: Synthesis and cdc2 inhibitory activity of olomoucine and related compounds
-
Havlicek L, Hanus J, Vesely J, et al. Cytokinin-derived cyclin-dependent kinase inhibitors: synthesis and cdc2 inhibitory activity of olomoucine and related compounds. J Med Chem 1997; 40:408-412.
-
(1997)
J Med Chem
, vol.40
, pp. 408-412
-
-
Havlicek, L.1
Hanus, J.2
Vesely, J.3
-
32
-
-
0023128405
-
Identification of viral molecules recognized by influenza-specific human cytotoxic T lymphocytes
-
Gotch F, McMichael A, Smith G, Moss B. Identification of viral molecules recognized by influenza-specific human cytotoxic T lymphocytes. J Exp Med 1987; 165:408-416.
-
(1987)
J Exp Med
, vol.165
, pp. 408-416
-
-
Gotch, F.1
McMichael, A.2
Smith, G.3
Moss, B.4
-
33
-
-
7444237148
-
Characterization and manipulation of the human adenovirus 4 genome
-
Jacobs SC, Davison AJ, Carr S, et al. Characterization and manipulation of the human adenovirus 4 genome. J Gen Virol 2004; 85:3361-3366.
-
(2004)
J Gen Virol
, vol.85
, pp. 3361-3366
-
-
Jacobs, S.C.1
Davison, A.J.2
Carr, S.3
-
34
-
-
0041351951
-
The most abundantly transcribed human cytomegalovirus gene (beta 2.7) is non-essential for growth in vitro
-
McSharry BP, Tomasec P, Neale ML, Wilkinson GW. The most abundantly transcribed human cytomegalovirus gene (beta 2.7) is non-essential for growth in vitro. J Gen Virol 2003; 84:2511-2516.
-
(2003)
J Gen Virol
, vol.84
, pp. 2511-2516
-
-
McSharry, B.P.1
Tomasec, P.2
Neale, M.L.3
Wilkinson, G.W.4
-
36
-
-
0035891288
-
7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes
-
Nguyen VT, Kiss T, Michels AA, Bensaude O. 7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes. Nature 2001; 414:322-325.
-
(2001)
Nature
, vol.414
, pp. 322-325
-
-
Nguyen, V.T.1
Kiss, T.2
Michels, A.A.3
Bensaude, O.4
-
37
-
-
0037071899
-
Physical interaction between pRb and cdk9/cyclinT2 complex
-
Simone C, Bagella L, Bellan C, Giordano A. Physical interaction between pRb and cdk9/cyclinT2 complex. Oncogene 2002; 21:4158-4165.
-
(2002)
Oncogene
, vol.21
, pp. 4158-4165
-
-
Simone, C.1
Bagella, L.2
Bellan, C.3
Giordano, A.4
-
38
-
-
0036275982
-
Phosphorylation of the RNA polymerase II carboxylterminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongation
-
Kim YK, Bourgeois CF, Isel C, Churcher MJ, Karn J. Phosphorylation of the RNA polymerase II carboxylterminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongation. Mol Cell Biol 2002; 22:4622-4637.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 4622-4637
-
-
Kim, Y.K.1
Bourgeois, C.F.2
Isel, C.3
Churcher, M.J.4
Karn, J.5
-
40
-
-
0028931265
-
Principles of CDK regulation
-
Morgan DO. Principles of CDK regulation. Nature 1995; 374:131-134.
-
(1995)
Nature
, vol.374
, pp. 131-134
-
-
Morgan, D.O.1
-
41
-
-
27144458683
-
Cyclins and CDKS in development and cancer: Lessons from genetically modified mice
-
Santamaria D, Ortega S. Cyclins and CDKS in development and cancer: lessons from genetically modified mice. Front Biosci 2006; 11:1164-1188.
-
(2006)
Front Biosci
, vol.11
, pp. 1164-1188
-
-
Santamaria, D.1
Ortega, S.2
-
42
-
-
0034121281
-
Cell cycle molecular targets in novel anticancer drug discovery
-
Buolamwini JK. Cell cycle molecular targets in novel anticancer drug discovery. Curr Pharm Des 2000; 6:379-392.
-
(2000)
Curr Pharm Des
, vol.6
, pp. 379-392
-
-
Buolamwini, J.K.1
-
43
-
-
0018648470
-
Biogenesis of poxviruses: Role for the DNA-dependent RNA polymerase II of the host during expression of late functions
-
Silver M, McFadden G, Wilton S, Dales S. Biogenesis of poxviruses: role for the DNA-dependent RNA polymerase II of the host during expression of late functions. Proc Natl Acad Sci U S A 1979; 76:4122-4125.
-
(1979)
Proc Natl Acad Sci U S A
, vol.76
, pp. 4122-4125
-
-
Silver, M.1
McFadden, G.2
Wilton, S.3
Dales, S.4
-
44
-
-
38849091239
-
Vaccinia virus-mediated cell cycle alteration involves inactivation of tumour suppressors associated with Brf1 and TBP
-
Yoo NK, Pyo CW, Kim Y, Ahn BY, Choi SY. Vaccinia virus-mediated cell cycle alteration involves inactivation of tumour suppressors associated with Brf1 and TBP. Cell Microbiol 2008; 10:583-592.
-
(2008)
Cell Microbiol
, vol.10
, pp. 583-592
-
-
Yoo, N.K.1
Pyo, C.W.2
Kim, Y.3
Ahn, B.Y.4
Choi, S.Y.5
-
45
-
-
0037310655
-
Adenovirus: An increasingly important pathogen in paediatric bone marrow transplant patients
-
Walls T, Shankar AG, Shingadia D. Adenovirus: an increasingly important pathogen in paediatric bone marrow transplant patients. Lancet Infect Dis 2003; 3:79-86.
-
(2003)
Lancet Infect Dis
, vol.3
, pp. 79-86
-
-
Walls, T.1
Shankar, A.G.2
Shingadia, D.3
-
46
-
-
0034858413
-
Adenoviral infections and a prospective trial of cidofovir in pediatric hematopoietic stem cell transplantation
-
Hoffman JA, Shah AJ, Ross LA, Kapoor N. Adenoviral infections and a prospective trial of cidofovir in pediatric hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2001; 7:388-394.
-
(2001)
Biol Blood Marrow Transplant
, vol.7
, pp. 388-394
-
-
Hoffman, J.A.1
Shah, A.J.2
Ross, L.A.3
Kapoor, N.4
-
47
-
-
0037366835
-
Cidofovir for adenovirus infections after allogeneic hematopoietic stem cell transplantation: A survey by the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation
-
Ljungman P, Ribaud P, Eyrich M, et al. Cidofovir for adenovirus infections after allogeneic hematopoietic stem cell transplantation: a survey by the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant 2003; 31:481-486.
-
(2003)
Bone Marrow Transplant
, vol.31
, pp. 481-486
-
-
Ljungman, P.1
Ribaud, P.2
Eyrich, M.3
|