Synthesis and biological activity of Olomoucine II

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 22, 2002, Pages 3283-3286

  Kryštof, Vladimír ^a   Lenobel, René ^a   Havlíček, Libor ^b   Kuzma, Marek ^c   Strnad, Miroslav ^a  

^a PALACKÝ UNIVERSITY   (Czech Republic)

^b INSTITUTE OF EXPERIMENTAL BOTANY   (Czech Republic)

^c INSTITUTE OF MICROBIOLOGY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN B; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE INHIBITOR; OLOMOUCINE; PURVALANOL; ROSCOVITINE; 6 ((3 CHLORO)ANILINO) 2 (ISOPROPYL 2 HYDROXYETHYLAMINO) 9 ISOPROPYLPURINE; 6-((3-CHLORO)ANILINO)-2-(ISOPROPYL-2-HYDROXYETHYLAMINO)-9-ISOPROPYLPURINE; ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; KINETIN; OLOMOUCINE II; PURINE DERIVATIVE;

ARTICLE; ASSAY; CELL LINE; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SPECIFICITY; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; IN VITRO STUDY; CELL CULTURE; CELL SURVIVAL; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; HUMAN; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTINEOPLASTIC AGENTS; CDC2 PROTEIN KINASE; CDC28 PROTEIN KINASE, S CEREVISIAE; CELL SURVIVAL; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; HUMANS; KINETIN; PURINES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0037131730     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00693-5     Document Type: Article

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14. Abstract
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