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Volumn 11, Issue 2, 2010, Pages 544-561

Novel neuroprotective strategies in ischemic retinal lesions

Author keywords

BCCAO; Diazoxide; Ischemia; PACAP; PARP inhibitor; Rat retina; Retinoprotection; Urocortin 2

Indexed keywords

ADENOSINE; ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA TOCOPHEROL; BASIC FIBROBLAST GROWTH FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; BRIMONIDINE; CALCIUM CHANNEL BLOCKING AGENT; CANNABINOID; CARNITINE; CILIARY NEUROTROPHIC FACTOR; DIAZOXIDE; ERYTHROPOIETIN; ESTRADIOL; FLAVONOID; GLUTAMATE RECEPTOR ANTAGONIST; HO 3089; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; MORPHINE; NERVE GROWTH FACTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PIGMENT EPITHELIUM DERIVED FACTOR; POTASSIUM CHANNEL BLOCKING AGENT; SCATTER FACTOR; SODIUM CHANNEL BLOCKING AGENT; SOMATOMEDIN B; UNCLASSIFIED DRUG; UROCORTIN I; UROCORTIN II; VASCULOTROPIN; XANTHOPHYLL;

EID: 77649211292     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms11020544     Document Type: Review
Times cited : (30)

References (138)
  • 3
    • 59949092983 scopus 로고    scopus 로고
    • Age-related maculopathy-linking aetiology and pathophysiologycal changes to the ischaemia hypothesis
    • Feigl, B. Age-related maculopathy-linking aetiology and pathophysiologycal changes to the ischaemia hypothesis. Prog. Retin. Eye Res. 2009, 28, 63-86.
    • (2009) Prog. Retin. Eye Res , vol.28 , pp. 63-86
    • Feigl, B.1
  • 4
    • 55849146641 scopus 로고    scopus 로고
    • Blood-retinal barrier in hypoxic ischaemic conditions: Basic concepts, clinical features and management
    • Kaur, C.; Foulds W.S.; Ling, E.A. Blood-retinal barrier in hypoxic ischaemic conditions: basic concepts, clinical features and management. Prog. Retin. Eye Res. 2008, 27, 622-647.
    • (2008) Prog. Retin. Eye Res , vol.27 , pp. 622-647
    • Kaur, C.1    Foulds, W.S.2    Ling, E.A.3
  • 6
    • 34047219721 scopus 로고    scopus 로고
    • Ocular ischemic syndrome: Review of clinical presentations, etiology, investigation, and management
    • Chen, C.S.; Miller, N.R. Ocular ischemic syndrome: review of clinical presentations, etiology, investigation, and management. Compr. Ophthalmol. 2007, 8, 17-28.
    • (2007) Compr. Ophthalmol , vol.8 , pp. 17-28
    • Chen, C.S.1    Miller, N.R.2
  • 8
    • 66249104676 scopus 로고    scopus 로고
    • Inner retinal ischemia: Current understanding and needs for further investigations
    • Bek, T. Inner retinal ischemia: current understanding and needs for further investigations. Acta Ophthalmol. 2009, 87, 362-367.
    • (2009) Acta Ophthalmol , vol.87 , pp. 362-367
    • Bek, T.1
  • 9
    • 1342312504 scopus 로고    scopus 로고
    • Endogenous neuroprotection in the retina
    • Roth, S. Endogenous neuroprotection in the retina. Brain Res. Bull. 2004, 62, 461-466.
    • (2004) Brain Res. Bull , vol.62 , pp. 461-466
    • Roth, S.1
  • 11
    • 49249132708 scopus 로고    scopus 로고
    • Neurogenereration and cellular stress in the retina and optic nerve in rat cerebral ischemia and hypoperfusion models
    • Kalesnykas, G.; Tuulos, T.; Uusitalo, H.; Jolkkonen, J. Neurogenereration and cellular stress in the retina and optic nerve in rat cerebral ischemia and hypoperfusion models. Neuroscience 2008, 55, 937-947.
    • (2008) Neuroscience , vol.55 , pp. 937-947
    • Kalesnykas, G.1    Tuulos, T.2    Uusitalo, H.3    Jolkkonen, J.4
  • 12
    • 33947646259 scopus 로고    scopus 로고
    • Permanent, bilateral common carotid artery occlusion in the rat: A model for chronic cerebral hypoperfusion-related neurodegenerative diseases
    • Farkas, E.; Luiten, P.G.; Bari, F. Permanent, bilateral common carotid artery occlusion in the rat: A model for chronic cerebral hypoperfusion-related neurodegenerative diseases. Brain Res. Rev. 2007, 54, 162-180.
    • (2007) Brain Res. Rev , vol.54 , pp. 162-180
    • Farkas, E.1    Luiten, P.G.2    Bari, F.3
  • 14
    • 0021744995 scopus 로고
    • Experimental carotid occlusion: Funduscopic and fluorescein angiographic findings
    • Spertus, A.D.; Slakter, J.S.; Weissman, S.S.; Henkind, P. Experimental carotid occlusion: funduscopic and fluorescein angiographic findings. Br. J. Ophtalmol. 1984, 68, 47-57.
    • (1984) Br. J. Ophtalmol , vol.68 , pp. 47-57
    • Spertus, A.D.1    Slakter, J.S.2    Weissman, S.S.3    Henkind, P.4
  • 15
    • 0026686696 scopus 로고
    • Retinal ischemia induced by occlusion of both common carotid arteries in rats as demonstrated by electroretinography
    • Block, F.; Schwarz, M.; Sontag, K.H. Retinal ischemia induced by occlusion of both common carotid arteries in rats as demonstrated by electroretinography. Neurosci. Lett. 1992, 144, 124-126.
    • (1992) Neurosci. Lett , vol.144 , pp. 124-126
    • Block, F.1    Schwarz, M.2    Sontag, K.H.3
  • 16
    • 0032835337 scopus 로고    scopus 로고
    • Photoreceptors are preferentially affected in the rat retina following permanent occlusion of the carotid arteries
    • Osborne, N.N.; Safa, R.; Nash, M.S. Photoreceptors are preferentially affected in the rat retina following permanent occlusion of the carotid arteries. Vision Res. 1999, 39, 3995-4002.
    • (1999) Vision Res , vol.39 , pp. 3995-4002
    • Osborne, N.N.1    Safa, R.2    Nash, M.S.3
  • 17
    • 0036219702 scopus 로고    scopus 로고
    • Retinal and optic nerve degeneration after chronic carotid ligation
    • Stevens, W.D.; Fortin, T.; Pappas, B.A. Retinal and optic nerve degeneration after chronic carotid ligation. Stroke 2002, 33, 1107-1112.
    • (2002) Stroke , vol.33 , pp. 1107-1112
    • Stevens, W.D.1    Fortin, T.2    Pappas, B.A.3
  • 18
    • 31644442047 scopus 로고    scopus 로고
    • Complex neurodegeneration in retina following moderate ischemia induced by bilateral common carotid artery occlusion in Wistar rats
    • Yamamoto, H.; Schmidt-Kasner, R.; Hamasaki, D.I.; Yamamoto, H.; Parel, J.M. Complex neurodegeneration in retina following moderate ischemia induced by bilateral common carotid artery occlusion in Wistar rats. Exp. Eye Res. 2006, 82, 767-779.
    • (2006) Exp. Eye Res , vol.82 , pp. 767-779
    • Yamamoto, H.1    Schmidt-Kasner, R.2    Hamasaki, D.I.3    Yamamoto, H.4    Parel, J.M.5
  • 19
    • 33644527549 scopus 로고    scopus 로고
    • Chronic bilateral common carotid artery occlusion: A model for ocular ischemic syndrome in the rat
    • Lavinsky, D.; Arterni, N.S.; Achaval, M.; Netto, C.A. Chronic bilateral common carotid artery occlusion: a model for ocular ischemic syndrome in the rat. Graefe's Arch. Clin. Exp. Ophthalmol. 2006, 244, 199-204.
    • (2006) Graefe's Arch. Clin. Exp. Ophthalmol , vol.244 , pp. 199-204
    • Lavinsky, D.1    Arterni, N.S.2    Achaval, M.3    Netto, C.A.4
  • 20
    • 70349729991 scopus 로고    scopus 로고
    • Protection against chronic hypoperfusion-induced retinal neurodegeneration by PARP inhibition via activation of PI3-kinase Akt pathway and suppression of JNK and p38 MAP kinases
    • Mester, L.; Szabo, A.; Atlasz, T.; Szabadfi, K.; Reglodi, D.; Kiss, P.; Racz, B.; Tamas, A.; Gallyas, F.; Sumegi, B.; Hocsak, E.; Gabriel, R.; Kovacs, K. Protection against chronic hypoperfusion-induced retinal neurodegeneration by PARP inhibition via activation of PI3-kinase Akt pathway and suppression of JNK and p38 MAP kinases. Neurotox. Res. 2009, 18, 68-76.
    • (2009) Neurotox. Res , vol.18 , pp. 68-76
    • Mester, L.1    Szabo, A.2    Atlasz, T.3    Szabadfi, K.4    Reglodi, D.5    Kiss, P.6    Racz, B.7    Tamas, A.8    Gallyas, F.9    Sumegi, B.10    Hocsak, E.11    Gabriel, R.12    Kovacs, K.13
  • 24
    • 59449098831 scopus 로고    scopus 로고
    • Effect of lutein on retinal neurons and oxidative stress in a model of acute retinal ischemia/reperfusion
    • Li, S.Y.; Fu, Z.J.; Ma, H.; Jang, W.C.; So, K.F.; Wong, D.; Lo, A.C. Effect of lutein on retinal neurons and oxidative stress in a model of acute retinal ischemia/reperfusion. Invest. Ophthalmol. Vis. Sci. 2009, 50, 836-843.
    • (2009) Invest. Ophthalmol. Vis. Sci , vol.50 , pp. 836-843
    • Li, S.Y.1    Fu, Z.J.2    Ma, H.3    Jang, W.C.4    So, K.F.5    Wong, D.6    Lo, A.C.7
  • 25
    • 39149116017 scopus 로고    scopus 로고
    • Flavonoids protect retinal ganglion cells from ischemia in vitro
    • Maher, P.; Hanneken, A. Flavonoids protect retinal ganglion cells from ischemia in vitro. Exp. Eye Res. 2008, 86, 366-374.
    • (2008) Exp. Eye Res , vol.86 , pp. 366-374
    • Maher, P.1    Hanneken, A.2
  • 28
    • 3042567243 scopus 로고    scopus 로고
    • Histological protection against ischemia-reperfusion injury by early ischemic preconditioning in rat retina
    • Sakamoto, K.; Yonoki, Y.; Kuwagata, M.; Saito, M.; Nakahara, T.; Ishii, K. Histological protection against ischemia-reperfusion injury by early ischemic preconditioning in rat retina. Brain Res. 2004, 1015, 154-160.
    • (2004) Brain Res , vol.1015 , pp. 154-160
    • Sakamoto, K.1    Yonoki, Y.2    Kuwagata, M.3    Saito, M.4    Nakahara, T.5    Ishii, K.6
  • 29
    • 67349191239 scopus 로고    scopus 로고
    • Preconditioning-induced protection from oxidative injury is mediated by leukemia inhibitory factor receptor (LIFR) and its ligands in the retina
    • Chollangi, S.; Wang, J.; Martin, A.; Quinn, J.; Ash, J.D. Preconditioning-induced protection from oxidative injury is mediated by leukemia inhibitory factor receptor (LIFR) and its ligands in the retina. Neurobiol. Dis. 2009, 34, 535-544.
    • (2009) Neurobiol. Dis , vol.34 , pp. 535-544
    • Chollangi, S.1    Wang, J.2    Martin, A.3    Quinn, J.4    Ash, J.D.5
  • 30
  • 31
    • 70349337148 scopus 로고    scopus 로고
    • Involvement of glutamate in retinal protection against ischemia/reperfusion damage induced by post-conditioning
    • Fernandez, D.C.; Chianelli, M.S.; Rosenstein, R.E. Involvement of glutamate in retinal protection against ischemia/reperfusion damage induced by post-conditioning. J. Neurochem. 2009, 111, 488-498.
    • (2009) J. Neurochem , vol.111 , pp. 488-498
    • Fernandez, D.C.1    Chianelli, M.S.2    Rosenstein, R.E.3
  • 32
    • 0037235610 scopus 로고    scopus 로고
    • Multiple effects of adenosine in the arterially perfused mammalian eye. Possible mechanisms for the neuroprotective function of adenosine in the retina
    • Macaluso, C.; Frishman, L.J.; Frueh, B.; Kaelin-Lang, A.; Onoe, S.; Niemeyer, G. Multiple effects of adenosine in the arterially perfused mammalian eye. Possible mechanisms for the neuroprotective function of adenosine in the retina. Doc. Ophthalmol. 2003, 106, 51-59.
    • (2003) Doc. Ophthalmol , vol.106 , pp. 51-59
    • Macaluso, C.1    Frishman, L.J.2    Frueh, B.3    Kaelin-Lang, A.4    Onoe, S.5    Niemeyer, G.6
  • 33
    • 0033094514 scopus 로고    scopus 로고
    • Administration of nerve growth factor, brain-derived neurotrophic factor and insulin-like growth factor-II protects phosphate-activated glutaminase in the ischemic and reperfused rat retinas
    • Tomita, H.; Ishiguro, S.; Abe, T.; Tamai, M. Administration of nerve growth factor, brain-derived neurotrophic factor and insulin-like growth factor-II protects phosphate-activated glutaminase in the ischemic and reperfused rat retinas. Tohoku J. Exp. Med. 1999, 187, 227-236.
    • (1999) Tohoku J. Exp. Med , vol.187 , pp. 227-236
    • Tomita, H.1    Ishiguro, S.2    Abe, T.3    Tamai, M.4
  • 34
  • 38
    • 77954027338 scopus 로고    scopus 로고
    • Erythropoietin protects retinal ganglion cells and visual function after ocular ischemia and optic nerve compression
    • in press
    • Jehle, T.; Meschede, W.; Dersch, R.; Feltgen, N.; Bach, M.; Lagreze, W.A. Erythropoietin protects retinal ganglion cells and visual function after ocular ischemia and optic nerve compression. Ophthalmologe 2009, in press.
    • (2009) Ophthalmologe
    • Jehle, T.1    Meschede, W.2    Dersch, R.3    Feltgen, N.4    Bach, M.5    Lagreze, W.A.6
  • 39
    • 56149102958 scopus 로고    scopus 로고
    • Statins modulate heat shock protein expression and enhance retinal ganglion cell survival after transient retinal ischemia/reperfusion in vivo
    • Schmeer, C.; Gamez, A.; Tausch, S.; Witte, O.W.; Isenmann, S. Statins modulate heat shock protein expression and enhance retinal ganglion cell survival after transient retinal ischemia/reperfusion in vivo. Invest. Ophthalmol. Vis. Sci. 2008, 49, 4971-4981.
    • (2008) Invest. Ophthalmol. Vis. Sci , vol.49 , pp. 4971-4981
    • Schmeer, C.1    Gamez, A.2    Tausch, S.3    Witte, O.W.4    Isenmann, S.5
  • 41
    • 0142151067 scopus 로고    scopus 로고
    • Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol in N-methyl-D-aspartate-induced retinal neurotoxicity: Involvement of peroxynitrite
    • El-Remessy, A.B.; Khalil, I.E.; Matragoon, S.; Abou-Mohamed, G.; Tsai, N.J.; Roon, P.; Caldwell, R.B.; Caldwell, R.W.; Green, K.; Liou, G.I. Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol in N-methyl-D-aspartate-induced retinal neurotoxicity: involvement of peroxynitrite. Am. J. Pathol. 2003, 163, 1997-2008.
    • (2003) Am. J. Pathol , vol.163 , pp. 1997-2008
    • El-Remessy, A.B.1    Khalil, I.E.2    Matragoon, S.3    Abou-Mohamed, G.4    Tsai, N.J.5    Roon, P.6    Caldwell, R.B.7    Caldwell, R.W.8    Green, K.9    Liou, G.I.10
  • 42
    • 40449112638 scopus 로고    scopus 로고
    • Morphine pretreatment provides histologic protection against ischemia-reperfusion injury in rabbit retina
    • Riazi-Esfahani, M.; Kiumehr, S.; Asadi-Amoli, F.; Lashay, A.R.; Dehpour, A.R. Morphine pretreatment provides histologic protection against ischemia-reperfusion injury in rabbit retina. Retina 2008, 28, 511-517.
    • (2008) Retina , vol.28 , pp. 511-517
    • Riazi-Esfahani, M.1    Kiumehr, S.2    Asadi-Amoli, F.3    Lashay, A.R.4    Dehpour, A.R.5
  • 43
    • 63249117737 scopus 로고    scopus 로고
    • Effects of intravitreal morphine administered at different time points after reperfusion in a rabbit model of ischemic retinopathy
    • Riazi-Esfahani, M.; Kiumehr, S.; Asadi-Amoli, F.; Dehpour, A.R. Effects of intravitreal morphine administered at different time points after reperfusion in a rabbit model of ischemic retinopathy. Retina 2009, 29, 262-268.
    • (2009) Retina , vol.29 , pp. 262-268
    • Riazi-Esfahani, M.1    Kiumehr, S.2    Asadi-Amoli, F.3    Dehpour, A.R.4
  • 44
    • 0037242545 scopus 로고    scopus 로고
    • Protection of the retina from ischemia-reperfusion injury by L-carnitine in guinea pigs
    • Kocer, I.; Kulacoglu, D.; Altuntas, I.; Gundogdu, C.; Gullulu, G. Protection of the retina from ischemia-reperfusion injury by L-carnitine in guinea pigs. Eur. J. Ophthalmol. 2003, 13, 80-85.
    • (2003) Eur. J. Ophthalmol , vol.13 , pp. 80-85
    • Kocer, I.1    Kulacoglu, D.2    Altuntas, I.3    Gundogdu, C.4    Gullulu, G.5
  • 45
    • 0028564781 scopus 로고
    • Glutamate receptor antagonists protect against ischemia-induced retinal damage
    • Lombardi, G.; Moroni, F. Glutamate receptor antagonists protect against ischemia-induced retinal damage. Eur. J. Pharmacol. 1994, 271, 489-495.
    • (1994) Eur. J. Pharmacol , vol.271 , pp. 489-495
    • Lombardi, G.1    Moroni, F.2
  • 46
    • 0037375287 scopus 로고    scopus 로고
    • The beta-adrenoceptor antagonists metipranolol and timolol are retinal neuroprotectants: Comparison with betaxolol
    • Wood, J.P.; Schmidt, K.G.; Melena, J.; Chidlow, G.; Allmeier, H.; Osborne, N.N. The beta-adrenoceptor antagonists metipranolol and timolol are retinal neuroprotectants: comparison with betaxolol. Exp. Eye Res. 2003, 76, 505-516.
    • (2003) Exp. Eye Res , vol.76 , pp. 505-516
    • Wood, J.P.1    Schmidt, K.G.2    Melena, J.3    Chidlow, G.4    Allmeier, H.5    Osborne, N.N.6
  • 47
    • 0035198185 scopus 로고    scopus 로고
    • Alpha(2)-Adrenoceptor agonists inhibit vitreal glutamate and aspartate accumulation and preserve retinal function after transient ischemia
    • Donello, J.E.; Padillo, E.U.; Webster, M.L.; Wheeler, L.A.; Gil, D.W. Alpha(2)-Adrenoceptor agonists inhibit vitreal glutamate and aspartate accumulation and preserve retinal function after transient ischemia. J. Pharmacol. Exp. Ther. 2001, 296, 216-223.
    • (2001) J. Pharmacol. Exp. Ther , vol.296 , pp. 216-223
    • Donello, J.E.1    Padillo, E.U.2    Webster, M.L.3    Wheeler, L.A.4    Gil, D.W.5
  • 48
    • 0035951654 scopus 로고    scopus 로고
    • ATP-sensitive potassium channels [K(ATP)] in retina: A key role for delayed ischemic tolerance
    • Ettaiche, M.; Heurteaux, C.; Blondeau, N.; Borsotto, M.; Tinel, N.; Lazdunski, M. ATP-sensitive potassium channels [K(ATP)] in retina: a key role for delayed ischemic tolerance. Brain Res. 2001, 890, 118-129.
    • (2001) Brain Res , vol.890 , pp. 118-129
    • Ettaiche, M.1    Heurteaux, C.2    Blondeau, N.3    Borsotto, M.4    Tinel, N.5    Lazdunski, M.6
  • 49
    • 64849105091 scopus 로고    scopus 로고
    • Histological protection by cilnidipine, a dual L/N-type Ca(2+) channel blocker, against neurotoxicity induced by ischemia-reperfusion in rat retina
    • Sakamoto, K.; Kawakami, T.; Shimada, M.; Yamaguchi, A.; Kuwagata, M.; Saito, M.; Nakahara, T.; Ishii, K. Histological protection by cilnidipine, a dual L/N-type Ca(2+) channel blocker, against neurotoxicity induced by ischemia-reperfusion in rat retina. Exp. Eye Res. 2009, 88, 974-982.
    • (2009) Exp. Eye Res , vol.88 , pp. 974-982
    • Sakamoto, K.1    Kawakami, T.2    Shimada, M.3    Yamaguchi, A.4    Kuwagata, M.5    Saito, M.6    Nakahara, T.7    Ishii, K.8
  • 50
    • 61549086237 scopus 로고    scopus 로고
    • GABA agonists fail to protect the retina from ischemia-reperfusion injury
    • Traustason, S.; Eysteinsson, T.; Agnarsson, B.A.; Stefánsson, E. GABA agonists fail to protect the retina from ischemia-reperfusion injury. Exp. Eye Res. 2009, 88, 361-366.
    • (2009) Exp. Eye Res , vol.88 , pp. 361-366
    • Traustason, S.1    Eysteinsson, T.2    Agnarsson, B.A.3    Stefánsson, E.4
  • 52
    • 34047214228 scopus 로고    scopus 로고
    • Physiology, pharmacology, and therapeutic relevance of urocortins in mammals: Ancient CRF paralogs
    • Fekete, É.M.; Zorrilla, E.P. Physiology, pharmacology, and therapeutic relevance of urocortins in mammals: Ancient CRF paralogs. Front. Neuroendocrinol. 2007, 28, 1-27.
    • (2007) Front. Neuroendocrinol , vol.28 , pp. 1-27
    • Fekete, E.M.1    Zorrilla, E.P.2
  • 53
    • 13544277442 scopus 로고    scopus 로고
    • Mouse corticotropin-releasing factor receptor type 2alpha gene: Isolation, distribution, pharmacological characterization and regulation by stress and glucocorticoids
    • Chen, A.; Perrin, M.; Brar, B.; Li, C.; Jamieson, P.; Digruccio, M.; Lewis, K.; Vale, W. Mouse corticotropin-releasing factor receptor type 2alpha gene: isolation, distribution, pharmacological characterization and regulation by stress and glucocorticoids. Mol. Endocrinol. 2005, 19, 441-458.
    • (2005) Mol. Endocrinol , vol.19 , pp. 441-458
    • Chen, A.1    Perrin, M.2    Brar, B.3    Li, C.4    Jamieson, P.5    Digruccio, M.6    Lewis, K.7    Vale, W.8
  • 54
    • 0036247197 scopus 로고    scopus 로고
    • Molecules in focus urocortin
    • Latchman, D.S. Molecules in focus urocortin. Biochem. Cell Biol. 2002, 34, 907-910.
    • (2002) Biochem. Cell Biol , vol.34 , pp. 907-910
    • Latchman, D.S.1
  • 55
    • 38649086725 scopus 로고    scopus 로고
    • Urocortin and the brain
    • Pan, W.; Kastin, A.J. Urocortin and the brain. Prog. Neurobiol. 2008, 84, 148-156.
    • (2008) Prog. Neurobiol , vol.84 , pp. 148-156
    • Pan, W.1    Kastin, A.J.2
  • 58
    • 35348994855 scopus 로고    scopus 로고
    • Effects of urocortin, corticotropin-releasing factor (CRF) receptor agonist, and astressin, CRF receptor antagonist, on the sleep-wake pattern: Analysis by radiotelemetry in conscious rats
    • Uchida, M.; Suzuki, M.; Shimizu, K. Effects of urocortin, corticotropin-releasing factor (CRF) receptor agonist, and astressin, CRF receptor antagonist, on the sleep-wake pattern: analysis by radiotelemetry in conscious rats. Biol. Pharm. Bull. 2007, 10, 1895-1897.
    • (2007) Biol. Pharm. Bull , vol.10 , pp. 1895-1897
    • Uchida, M.1    Suzuki, M.2    Shimizu, K.3
  • 59
    • 9144224385 scopus 로고    scopus 로고
    • Urocortin-II and urocortin-III are cardioprotective against ischemia reperfusion injury: An essential endogenous cardioprotective role for corticotropin releasing factor receptor type 2 in the murine heart
    • Brar, B.K.; Jonassen, A.K.; Egorina, E.M.; Chen, A.; Negro, A.; Perrin, M.H.; Mjøs, O.D.; Latchman, D.S.; Lee, K.F.; Vale, W. Urocortin-II and urocortin-III are cardioprotective against ischemia reperfusion injury: an essential endogenous cardioprotective role for corticotropin releasing factor receptor type 2 in the murine heart. Endocrinology 2004, 145, 24-35.
    • (2004) Endocrinology , vol.145 , pp. 24-35
    • Brar, B.K.1    Jonassen, A.K.2    Egorina, E.M.3    Chen, A.4    Negro, A.5    Perrin, M.H.6    Mjøs, O.D.7    Latchman, D.S.8    Lee, K.F.9    Vale, W.10
  • 60
    • 23844488100 scopus 로고    scopus 로고
    • In vivo protective effects of urocortin on ischemiareperfusion injury in rat heart via free radical mechanisms
    • Liu, C.N.; Yang, C.; Liu, X.Y.; Li, S. In vivo protective effects of urocortin on ischemiareperfusion injury in rat heart via free radical mechanisms. Can. J. Physiol. Pharmacol. 2005, 83, 459-465.
    • (2005) Can. J. Physiol. Pharmacol , vol.83 , pp. 459-465
    • Liu, C.N.1    Yang, C.2    Liu, X.Y.3    Li, S.4
  • 61
    • 34447643895 scopus 로고    scopus 로고
    • Urocortin: Cardiovascular actions and therapeutic implications
    • Rademaker, M.T. Urocortin: cardiovascular actions and therapeutic implications. Lett. Drug Des. Discov. 2004, 1, 168-172.
    • (2004) Lett. Drug Des. Discov , vol.1 , pp. 168-172
    • Rademaker, M.T.1
  • 62
    • 25144452474 scopus 로고    scopus 로고
    • Effects of UCN via ion mechanisms or CRF receptors?
    • Tao, J.; Li, S. Effects of UCN via ion mechanisms or CRF receptors? Biochem. Biophys. Res. Commun. 2005, 336, 731-736.
    • (2005) Biochem. Biophys. Res. Commun , vol.336 , pp. 731-736
    • Tao, J.1    Li, S.2
  • 63
    • 0042071566 scopus 로고    scopus 로고
    • Corticotropin-releasing factor (CRF) and related peptides confer neuroprotection via type 1 CRF receptors
    • Facci, L.; Stevens, D.A.; Pangallo, M.; Franceschini, D.; Skaper, S.D.; Strijbos, P.J.L.M. Corticotropin-releasing factor (CRF) and related peptides confer neuroprotection via type 1 CRF receptors. Neuropharmacol 2003, 45, 623-636.
    • (2003) Neuropharmacol , vol.45 , pp. 623-636
    • Facci, L.1    Stevens, D.A.2    Pangallo, M.3    Franceschini, D.4    Skaper, S.D.5    Strijbos, P.J.L.M.6
  • 64
    • 0037079998 scopus 로고    scopus 로고
    • Pedersen, W.A.; Wan, R.; Zhang, P.; Mattson, M.P. Urocortin, but not urocortin II, protects cultured hippocampal neurons from oxidative and excitotoxic cell death via corticotropin-releasing hormone receptor type I. J. Neurosci. 2002, 22, 404-412.
    • Pedersen, W.A.; Wan, R.; Zhang, P.; Mattson, M.P. Urocortin, but not urocortin II, protects cultured hippocampal neurons from oxidative and excitotoxic cell death via corticotropin-releasing hormone receptor type I. J. Neurosci. 2002, 22, 404-412.
  • 65
    • 0034059627 scopus 로고    scopus 로고
    • Evidence for the abundant expression of arginine 185 containing human CRF2 receptors and the role of position 185 for receptor-ligand selectivity
    • Dautzenberg, F.M.; Huber, G.; Higelin, J.; Py-Lang, G.; Kilpatrick, G.J. Evidence for the abundant expression of arginine 185 containing human CRF2 receptors and the role of position 185 for receptor-ligand selectivity. Neuropharmacol. 2000, 39, 1368-1376.
    • (2000) Neuropharmacol , vol.39 , pp. 1368-1376
    • Dautzenberg, F.M.1    Huber, G.2    Higelin, J.3    Py-Lang, G.4    Kilpatrick, G.J.5
  • 66
    • 34247391595 scopus 로고    scopus 로고
    • Expression of molecular equivalent of hypothalamic-pituitary-adrenal axis in adult retinal pigment epithelium
    • Zmijewski, M.A.; Sharma, R.K.; Slominski, A.T. Expression of molecular equivalent of hypothalamic-pituitary-adrenal axis in adult retinal pigment epithelium. J. Endocrinol. 2007, 193, 157-169.
    • (2007) J. Endocrinol , vol.193 , pp. 157-169
    • Zmijewski, M.A.1    Sharma, R.K.2    Slominski, A.T.3
  • 67
    • 0021260932 scopus 로고
    • Corticotropin releasing factor-like immunoreactive neurons in the rat retina
    • Skofitsch, G.; Jacobowitz, D.M. Corticotropin releasing factor-like immunoreactive neurons in the rat retina. Brain Res. Bull. 1984, 12, 539-542.
    • (1984) Brain Res. Bull , vol.12 , pp. 539-542
    • Skofitsch, G.1    Jacobowitz, D.M.2
  • 68
    • 0026132387 scopus 로고
    • Synaptic organization of two types of amacrine cells with CRF-like immunoreactivity in the turtle retina
    • Williamson, D.E.; Eldred, W.D. Synaptic organization of two types of amacrine cells with CRF-like immunoreactivity in the turtle retina. Vis. Neurosci. 1991, 6, 257-269.
    • (1991) Vis. Neurosci , vol.6 , pp. 257-269
    • Williamson, D.E.1    Eldred, W.D.2
  • 69
    • 0024600404 scopus 로고
    • Amacrine and ganglion cells with corticotropinreleasing-factor-like immunoreactivity in the turtle retina
    • Williamson, D.E.; Eldred, W.D. Amacrine and ganglion cells with corticotropinreleasing-factor-like immunoreactivity in the turtle retina. J. Comp. Neurol. 1989, 280, 424-435.
    • (1989) J. Comp. Neurol , vol.280 , pp. 424-435
    • Williamson, D.E.1    Eldred, W.D.2
  • 70
    • 0025069862 scopus 로고
    • Postnatal development of corticotrophin releasing factor-like immunoreactive amacrine cells in the rat retina
    • Zhang, D.R.; Gallagher, M.; Sladek, C.D.; Yeh, H.H. Postnatal development of corticotrophin releasing factor-like immunoreactive amacrine cells in the rat retina. Brain Res. Dev. Brain Res. 1990, 51, 185-194.
    • (1990) Brain Res. Dev. Brain Res , vol.51 , pp. 185-194
    • Zhang, D.R.1    Gallagher, M.2    Sladek, C.D.3    Yeh, H.H.4
  • 71
    • 0026149786 scopus 로고
    • Corticotropin releasing factor-like immunoreactivity (CRFLI) in horizontal cells of the developing rat retina
    • Zhang, D.R.; Yeh, H.H. Corticotropin releasing factor-like immunoreactivity (CRFLI) in horizontal cells of the developing rat retina. Vis. Neurosci. 1991, 6, 383-391.
    • (1991) Vis. Neurosci , vol.6 , pp. 383-391
    • Zhang, D.R.1    Yeh, H.H.2
  • 72
    • 0025308107 scopus 로고
    • Histogenesis of corticotropin releasing factor-like immunoreactive amacrine cells in the rat retina
    • Zhang, D.R.; Yeh, H.H. Histogenesis of corticotropin releasing factor-like immunoreactive amacrine cells in the rat retina. Brain Res. Dev. Brain Res. 1990, 53, 194-199.
    • (1990) Brain Res. Dev. Brain Res , vol.53 , pp. 194-199
    • Zhang, D.R.1    Yeh, H.H.2
  • 76
    • 0032727351 scopus 로고    scopus 로고
    • Mitochondrial potassium channel opener diazoxide preserves neuronal-vascular function after cerebral ischemia in newborn pigs
    • Domoki, F.; Perciaccante, J.V.; Veltkamp, R.; Bari, F.; Busija, D.W. Mitochondrial potassium channel opener diazoxide preserves neuronal-vascular function after cerebral ischemia in newborn pigs. Stroke 1999, 30, 2713-2718.
    • (1999) Stroke , vol.30 , pp. 2713-2718
    • Domoki, F.1    Perciaccante, J.V.2    Veltkamp, R.3    Bari, F.4    Busija, D.W.5
  • 77
    • 0036209260 scopus 로고    scopus 로고
    • Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release
    • Liu, D.; Lu, C.; Wan, R.; Auyeung, W.W.; Mattson, M.P. Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release. J. Cereb. Blood Flow Metab. 2002, 22, 431-443.
    • (2002) J. Cereb. Blood Flow Metab , vol.22 , pp. 431-443
    • Liu, D.1    Lu, C.2    Wan, R.3    Auyeung, W.W.4    Mattson, M.P.5
  • 78
    • 0038095182 scopus 로고    scopus 로고
    • Mitochondrial plasticity in classical ischemic preconditioning-moving beyond the mitochondrial KATP channel
    • Minners, J.; McLeod, C.J.; Sack, M.N. Mitochondrial plasticity in classical ischemic preconditioning-moving beyond the mitochondrial KATP channel. Cardiovasc. Res. 2003, 59, 1-6.
    • (2003) Cardiovasc. Res , vol.59 , pp. 1-6
    • Minners, J.1    McLeod, C.J.2    Sack, M.N.3
  • 80
    • 2542483507 scopus 로고    scopus 로고
    • Diazoxide preconditioning protects against neuronal cell death by attenuation of oxidative stress upon glutamate stimulation
    • Nagy, K.; Kis, B.; Rajapakse, N.C.; Bari, F.; Busija, D.W. Diazoxide preconditioning protects against neuronal cell death by attenuation of oxidative stress upon glutamate stimulation. J. Neurosci. Res. 2004, 76, 697-704.
    • (2004) J. Neurosci. Res , vol.76 , pp. 697-704
    • Nagy, K.1    Kis, B.2    Rajapakse, N.C.3    Bari, F.4    Busija, D.W.5
  • 81
    • 0038507050 scopus 로고    scopus 로고
    • Mitochondrial ATP-sensitive potassium channel activation protects cerebellar granule neurons from apoptosis induced by oxidative stress
    • Teshima, Y.; Akao, M.; Li, R.A.; Chong, T.H.; Baumgartner, W.A.; Johnston, M.V.; Marban, E. Mitochondrial ATP-sensitive potassium channel activation protects cerebellar granule neurons from apoptosis induced by oxidative stress. Stroke 2003, 34, 1796-1802.
    • (2003) Stroke , vol.34 , pp. 1796-1802
    • Teshima, Y.1    Akao, M.2    Li, R.A.3    Chong, T.H.4    Baumgartner, W.A.5    Johnston, M.V.6    Marban, E.7
  • 82
    • 0037491813 scopus 로고    scopus 로고
    • Diazoxide pretreatment induces delayed preconditioning in astrocytes against oxygen glucose deprivation and hydrogen peroxide-induced toxicity
    • Rajapakse, N.; Kis, B.; Horiguchi, T.; Snipes, J.; Busija, D.W. Diazoxide pretreatment induces delayed preconditioning in astrocytes against oxygen glucose deprivation and hydrogen peroxide-induced toxicity. J. Neurosci. Res. 2003, 73, 206-214.
    • (2003) J. Neurosci. Res , vol.73 , pp. 206-214
    • Rajapakse, N.1    Kis, B.2    Horiguchi, T.3    Snipes, J.4    Busija, D.W.5
  • 83
    • 4043092661 scopus 로고    scopus 로고
    • Diazoxide prevents mitochondrial swelling and Ca2+ accumulation in CA1 pyramidal cells after cerebral ischemia in newborn pigs
    • Domoki, F.; Bari, F.; Nagy, K.; Busija, D.W.; Siklós, L. Diazoxide prevents mitochondrial swelling and Ca2+ accumulation in CA1 pyramidal cells after cerebral ischemia in newborn pigs. Brain Res. 2004, 1019, 97-104.
    • (2004) Brain Res , vol.1019 , pp. 97-104
    • Domoki, F.1    Bari, F.2    Nagy, K.3    Busija, D.W.4    Siklós, L.5
  • 85
    • 0032807906 scopus 로고    scopus 로고
    • Mitochondrial ATP-dependent potassium channels. Viable candidate effectors of ischemic preconditioning
    • Liu, Y.; Sato, T.; Seharaseyon, J.; Szewczyk, A.; O'Rourke, B.; Marban, E. Mitochondrial ATP-dependent potassium channels. Viable candidate effectors of ischemic preconditioning. Ann. NY Acad. Sci. 1999, 874, 27-37.
    • (1999) Ann. NY Acad. Sci , vol.874 , pp. 27-37
    • Liu, Y.1    Sato, T.2    Seharaseyon, J.3    Szewczyk, A.4    O'Rourke, B.5    Marban, E.6
  • 87
    • 20744453559 scopus 로고    scopus 로고
    • Effects of ATP-sensitive potassium channel activators diazoxide and BMS-191095 on membrane potential and reactive oxygen species production in isolated piglet mitochondria
    • Busija, D.W.; Katakam, P.; Rajapakse, N.C.; Kis, B.; Grover, G.; Domoki, F.; Bari, F. Effects of ATP-sensitive potassium channel activators diazoxide and BMS-191095 on membrane potential and reactive oxygen species production in isolated piglet mitochondria. Brain Res. Bull. 2005, 66, 85-90.
    • (2005) Brain Res. Bull , vol.66 , pp. 85-90
    • Busija, D.W.1    Katakam, P.2    Rajapakse, N.C.3    Kis, B.4    Grover, G.5    Domoki, F.6    Bari, F.7
  • 88
    • 16644398901 scopus 로고    scopus 로고
    • Diazoxide and dimethyl sulphoxide alleviate experimental cerebral hypoperfusion-induced white matter injury in the rat brain
    • Farkas, E.; Annahazi, A.; Institoris, A.; Mihaly, A.; Luiten, P.G.; Bari, F. Diazoxide and dimethyl sulphoxide alleviate experimental cerebral hypoperfusion-induced white matter injury in the rat brain. Neurosci. Lett. 2005, 373, 195-199.
    • (2005) Neurosci. Lett , vol.373 , pp. 195-199
    • Farkas, E.1    Annahazi, A.2    Institoris, A.3    Mihaly, A.4    Luiten, P.G.5    Bari, F.6
  • 89
    • 23844552880 scopus 로고    scopus 로고
    • Post-ischemic administration of diazoxide attenuates long-term microglial activation in the rat brain after permanent carotid artery occlusion
    • Farkas, E.; Timmer, N.M.; Domoki, F.; Mihaly, A.; Luiten, P.G.; Bari, F. Post-ischemic administration of diazoxide attenuates long-term microglial activation in the rat brain after permanent carotid artery occlusion. Neurosci. Lett. 2005, 387, 168-172.
    • (2005) Neurosci. Lett , vol.387 , pp. 168-172
    • Farkas, E.1    Timmer, N.M.2    Domoki, F.3    Mihaly, A.4    Luiten, P.G.5    Bari, F.6
  • 90
    • 22144432288 scopus 로고    scopus 로고
    • Diazoxide preconditioning attenuates global cerebral ischemia-induced blood-brain barrier permeability
    • Lenzser, G.; Kis, B.; Bari, F.; Busija, D.W. Diazoxide preconditioning attenuates global cerebral ischemia-induced blood-brain barrier permeability. Brain Res. 2005, 1051, 72-80.
    • (2005) Brain Res , vol.1051 , pp. 72-80
    • Lenzser, G.1    Kis, B.2    Bari, F.3    Busija, D.W.4
  • 91
    • 2442473297 scopus 로고    scopus 로고
    • Diazoxide and dimethyl sulphoxide prevent cerebral hypoperfusion-related learning dysfunction and brain damage after carotid artery occlusion
    • Farkas, E.; Institoris, A.; Domoki, F.; Mihaly, A.; Luiten, P.G.; Bari, F. Diazoxide and dimethyl sulphoxide prevent cerebral hypoperfusion-related learning dysfunction and brain damage after carotid artery occlusion. Brain Res. 2004, 1008, 252-260.
    • (2004) Brain Res , vol.1008 , pp. 252-260
    • Farkas, E.1    Institoris, A.2    Domoki, F.3    Mihaly, A.4    Luiten, P.G.5    Bari, F.6
  • 92
    • 33646893482 scopus 로고    scopus 로고
    • The effect of pre- and posttreatment with diazoxide on the early phase of chronic cerebral hypoperfusion in the rat
    • Farkas, E.; Institoris, A.; Domoki, F.; Mihaly, A.; Bari, F. The effect of pre- and posttreatment with diazoxide on the early phase of chronic cerebral hypoperfusion in the rat. Brain Res. 2006, 1087, 168-174.
    • (2006) Brain Res , vol.1087 , pp. 168-174
    • Farkas, E.1    Institoris, A.2    Domoki, F.3    Mihaly, A.4    Bari, F.5
  • 93
    • 0037336141 scopus 로고    scopus 로고
    • Mechanism of inhibitory actions of oxidizing agents on calcium-activated potassium current in cultured pigment epithelial cells of the human retina
    • Sheu, S.J.; Wu, S.N. Mechanism of inhibitory actions of oxidizing agents on calcium-activated potassium current in cultured pigment epithelial cells of the human retina. Invest. Ophthalmol. Vis. Sci. 2003, 44, 1237-1244.
    • (2003) Invest. Ophthalmol. Vis. Sci , vol.44 , pp. 1237-1244
    • Sheu, S.J.1    Wu, S.N.2
  • 94
    • 1842728398 scopus 로고    scopus 로고
    • Retinal ganglion cell survival is enhanced by gabapentin-lactam in vitro: Evidence for involvement of mitochondrial KATP channels
    • Pielen, A.; Kirsch, M.; Hofmann, H.D.; Feuerstein, T.J.; Lagreze, W.A. Retinal ganglion cell survival is enhanced by gabapentin-lactam in vitro: evidence for involvement of mitochondrial KATP channels. Graefe's Arch. Clin. Exp. Ophthalmol. 2004, 242, 240-244.
    • (2004) Graefe's Arch. Clin. Exp. Ophthalmol , vol.242 , pp. 240-244
    • Pielen, A.1    Kirsch, M.2    Hofmann, H.D.3    Feuerstein, T.J.4    Lagreze, W.A.5
  • 95
    • 0027513827 scopus 로고
    • Consequences of transient retinal hypoxia on rod input to horizontal cells in the rat retina
    • Hankins, M.W.; Ikeda, H. Consequences of transient retinal hypoxia on rod input to horizontal cells in the rat retina. Vision Res. 1993, 33, 429-436.
    • (1993) Vision Res , vol.33 , pp. 429-436
    • Hankins, M.W.1    Ikeda, H.2
  • 97
    • 0033935668 scopus 로고    scopus 로고
    • Gabapentin-lactam (8-aza-spiro[5,4]decan-9-on; GBP-L) inhibits oxygen glucose deprivation-induced [3H]glutamate release and is a neuroprotective agent in a model of acute retinal ischemia
    • Jehle, T.; Lagreze, W.A.; Blauth, E.; Knorle, R.; Schnierle, P.; Lucking, C.H.; Feuerstein, T.J. Gabapentin-lactam (8-aza-spiro[5,4]decan-9-on; GBP-L) inhibits oxygen glucose deprivation-induced [3H]glutamate release and is a neuroprotective agent in a model of acute retinal ischemia. Naunyn Schmiedebergs Arch. Pharmacol. 2000, 362, 74-81.
    • (2000) Naunyn Schmiedebergs Arch. Pharmacol , vol.362 , pp. 74-81
    • Jehle, T.1    Lagreze, W.A.2    Blauth, E.3    Knorle, R.4    Schnierle, P.5    Lucking, C.H.6    Feuerstein, T.J.7
  • 98
    • 38449083387 scopus 로고    scopus 로고
    • Diazoxide is protective in the rat retina against ischemic injury induced by bilateral carotid occlusion and glutamate-induced degeneration
    • Atlasz, T.; Babai, N.; Reglodi, D.; Kiss, P.; Tamas, A.; Bari, F.; Domoki, F.; Gabriel, R. Diazoxide is protective in the rat retina against ischemic injury induced by bilateral carotid occlusion and glutamate-induced degeneration. Neurotox. Res. 2007, 12, 105-111.
    • (2007) Neurotox. Res , vol.12 , pp. 105-111
    • Atlasz, T.1    Babai, N.2    Reglodi, D.3    Kiss, P.4    Tamas, A.5    Bari, F.6    Domoki, F.7    Gabriel, R.8
  • 99
    • 0028198705 scopus 로고
    • Protection of the rat retina from ischemic injury by brain-derived neurotrophic factor, ciliary neurotrophic factor, and basic fibroblast growth factor
    • Unoki, K.; La Vail, M.M. Protection of the rat retina from ischemic injury by brain-derived neurotrophic factor, ciliary neurotrophic factor, and basic fibroblast growth factor. Invest. Ophtalmol. Vis. Sci. 1994, 35, 907-915.
    • (1994) Invest. Ophtalmol. Vis. Sci , vol.35 , pp. 907-915
    • Unoki, K.1    La Vail, M.M.2
  • 100
    • 0034832184 scopus 로고    scopus 로고
    • Pigment epithelium derived factor as a neuroprotective agent against ischemic retinal injury
    • Ogata, N.; Wang, L.; Jo, N.; Tombran-Tink, J.; Takahashi, K.; Mrazek, D.; Matsumura, M. Pigment epithelium derived factor as a neuroprotective agent against ischemic retinal injury. Curr. Eye Res. 2001, 22, 245-252.
    • (2001) Curr. Eye Res , vol.22 , pp. 245-252
    • Ogata, N.1    Wang, L.2    Jo, N.3    Tombran-Tink, J.4    Takahashi, K.5    Mrazek, D.6    Matsumura, M.7
  • 104
    • 4444305508 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase activating polypeptide: A potential neuroprotective peptide-review
    • Somogyvari-Vigh, A.; Reglodi, D. Pituitary adenylate cyclase activating polypeptide: a potential neuroprotective peptide-review. Curr. Pharm. Des. 2004, 10, 2861-2889.
    • (2004) Curr. Pharm. Des , vol.10 , pp. 2861-2889
    • Somogyvari-Vigh, A.1    Reglodi, D.2
  • 105
    • 0034505111 scopus 로고    scopus 로고
    • Gene expression for PACAP receptor mRNA in the rat retina by in situ hybridization and in situ RT-PCR
    • Seki, T.; Izumi, S.; Shioda, S.; Zhou, C.J.; Arimura, A.; Koide, R. Gene expression for PACAP receptor mRNA in the rat retina by in situ hybridization and in situ RT-PCR. Ann. N. Y. Acad. Sci. 2000, 921, 366-369.
    • (2000) Ann. N. Y. Acad. Sci , vol.921 , pp. 366-369
    • Seki, T.1    Izumi, S.2    Shioda, S.3    Zhou, C.J.4    Arimura, A.5    Koide, R.6
  • 106
    • 0031555301 scopus 로고    scopus 로고
    • Distribution and ultrastructural localization of a receptor for pituitary adenylate cyclase activating polypeptide and its mRNA in the rat retina
    • Seki, T.; Shioda, S.; Ogino, D.; Nakai, Y.; Arimura, A.; Koide, R. Distribution and ultrastructural localization of a receptor for pituitary adenylate cyclase activating polypeptide and its mRNA in the rat retina. Neurosci. Lett. 1997, 238, 127-130.
    • (1997) Neurosci. Lett , vol.238 , pp. 127-130
    • Seki, T.1    Shioda, S.2    Ogino, D.3    Nakai, Y.4    Arimura, A.5    Koide, R.6
  • 107
    • 0036971940 scopus 로고    scopus 로고
    • Multiple actions of pituitary adenylyl cyclase activating peptide in nervous system development and regeneration
    • Waschek, J.A. Multiple actions of pituitary adenylyl cyclase activating peptide in nervous system development and regeneration. Dev. Neurosci. 2002, 24, 14-23.
    • (2002) Dev. Neurosci , vol.24 , pp. 14-23
    • Waschek, J.A.1
  • 108
    • 0142094640 scopus 로고    scopus 로고
    • Expression of neuropeptides and their receptors in the developing retina of mammals
    • Bagnoli, P.; Dal Monte, M.; Casini, G. Expression of neuropeptides and their receptors in the developing retina of mammals. Histol. Histopathol. 2003, 18, 1219-1242.
    • (2003) Histol. Histopathol , vol.18 , pp. 1219-1242
    • Bagnoli, P.1    Dal Monte, M.2    Casini, G.3
  • 109
    • 23644449089 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase activating polypeptide (PACAP) can act as determinant of the tyrosine hydoxylase phenotype of dopaminergic cells during retina development
    • Borba, J.C.; Henze, I.P.; Silveira, M.S.; Kubrusly, R.C.; Gardino, P.F.; de Mello, M.C.; Hokoc, J.N.; de Mello, F.G. Pituitary adenylate cyclase activating polypeptide (PACAP) can act as determinant of the tyrosine hydoxylase phenotype of dopaminergic cells during retina development. Dev. Brain Res. 2005, 156, 193-201.
    • (2005) Dev. Brain Res , vol.156 , pp. 193-201
    • Borba, J.C.1    Henze, I.P.2    Silveira, M.S.3    Kubrusly, R.C.4    Gardino, P.F.5    de Mello, M.C.6    Hokoc, J.N.7    de Mello, F.G.8
  • 110
    • 0033592050 scopus 로고    scopus 로고
    • Attenuation by PACAP of glutamate-induced neurotoxicity in cultured retinal neurons
    • Shoge, K.; Mishima, H.K.; Saitoh, T.; Ishihara, K.; Tamura, Y.; Shiomi, H.; Sasa, M. Attenuation by PACAP of glutamate-induced neurotoxicity in cultured retinal neurons. Brain Res. 1999, 839, 66-73.
    • (1999) Brain Res , vol.839 , pp. 66-73
    • Shoge, K.1    Mishima, H.K.2    Saitoh, T.3    Ishihara, K.4    Tamura, Y.5    Shiomi, H.6    Sasa, M.7
  • 111
    • 0037013288 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase activating polypeptide prevents induced cell death in retinal tissue through activation of cyclic AMP-dependent protein kinase
    • Silveira, M.S.; Costa, M.R.; Bozza, M.; Linden, R. Pituitary adenylate cyclase activating polypeptide prevents induced cell death in retinal tissue through activation of cyclic AMP-dependent protein kinase. J. Biol. Chem. 2002, 277, 16075-16080.
    • (2002) J. Biol. Chem , vol.277 , pp. 16075-16080
    • Silveira, M.S.1    Costa, M.R.2    Bozza, M.3    Linden, R.4
  • 112
    • 0037111162 scopus 로고    scopus 로고
    • PACAP inhibits anoxia-induced changes in physiological responses in horizontal cells in the turtle retina
    • Rabl, K.; Reglodi, D.; Banvolgyi, T.; Somogyvari-Vigh, A.; Lengvari, I.; Gabriel, R.; Arimura, A. PACAP inhibits anoxia-induced changes in physiological responses in horizontal cells in the turtle retina. Regul. Pept. 2002, 109, 71-74.
    • (2002) Regul. Pept , vol.109 , pp. 71-74
    • Rabl, K.1    Reglodi, D.2    Banvolgyi, T.3    Somogyvari-Vigh, A.4    Lengvari, I.5    Gabriel, R.6    Arimura, A.7
  • 113
    • 58149085967 scopus 로고    scopus 로고
    • Suppression of ganglion cell death by PACAP following optic nerve transection in the rat
    • Seki, T.; Itoh, H.; Nakamachi, T.; Shioda, S. Suppression of ganglion cell death by PACAP following optic nerve transection in the rat. J. Mol. Neurosci. 2008, 36, 57-60.
    • (2008) J. Mol. Neurosci , vol.36 , pp. 57-60
    • Seki, T.1    Itoh, H.2    Nakamachi, T.3    Shioda, S.4
  • 114
    • 33746442839 scopus 로고    scopus 로고
    • Search for the optimal monosodium glutamate treatment schedule to study the neuroprotective effects of PACAP in the retina
    • Babai, N.; Atlasz, T.; Tamas, A.; Reglodi, D.; Toth, G.; Kiss, P.; Gabriel, R. Search for the optimal monosodium glutamate treatment schedule to study the neuroprotective effects of PACAP in the retina. Ann. N.Y. Acad. Sci. 2006, 1070, 149-155.
    • (2006) Ann. N.Y. Acad. Sci , vol.1070 , pp. 149-155
    • Babai, N.1    Atlasz, T.2    Tamas, A.3    Reglodi, D.4    Toth, G.5    Kiss, P.6    Gabriel, R.7
  • 115
    • 33645953958 scopus 로고    scopus 로고
    • Degree of damage compensation by various PACAP treatments in monosodium glutamate-induced retinal degeneration
    • Babai, N.; Atlasz, T.; Tamas, A.; Reglodi, D.; Toth, G.; Kiss, P.; Gabriel, R. Degree of damage compensation by various PACAP treatments in monosodium glutamate-induced retinal degeneration. Neurotox. Res. 2005, 8, 227-233.
    • (2005) Neurotox. Res , vol.8 , pp. 227-233
    • Babai, N.1    Atlasz, T.2    Tamas, A.3    Reglodi, D.4    Toth, G.5    Kiss, P.6    Gabriel, R.7
  • 116
    • 8644289375 scopus 로고    scopus 로고
    • Effects of pituitary adenylate cyclase activating polypeptide in retinal degeneration induced by monosodium-glutamate
    • Tamas, A.; Gabriel, R.; Racz, B.; Denes, V.; Kiss, P.; Lubics, A.; Lengvari, I.; Reglodi, D. Effects of pituitary adenylate cyclase activating polypeptide in retinal degeneration induced by monosodium-glutamate. Neurosci. Lett. 2004, 372, 110-113.
    • (2004) Neurosci. Lett , vol.372 , pp. 110-113
    • Tamas, A.1    Gabriel, R.2    Racz, B.3    Denes, V.4    Kiss, P.5    Lubics, A.6    Lengvari, I.7    Reglodi, D.8
  • 117
    • 65449131256 scopus 로고    scopus 로고
    • Effects of pituitary adenylate cyclase activating polypeptide (PACAP1-38) and its fragments on retinal degeneration induced by neonatal MSG treatment
    • Atlasz, T.; Szabadfi, K.; Reglodi, D.; Kiss, P.; Tamas, A.; Toth, G.; Molnar, A.; Szabo, K.; Gabriel, R. Effects of pituitary adenylate cyclase activating polypeptide (PACAP1-38) and its fragments on retinal degeneration induced by neonatal MSG treatment. Ann. NY Acad. Sci. 2009, 1163, 348-352.
    • (2009) Ann. NY Acad. Sci , vol.1163 , pp. 348-352
    • Atlasz, T.1    Szabadfi, K.2    Reglodi, D.3    Kiss, P.4    Tamas, A.5    Toth, G.6    Molnar, A.7    Szabo, K.8    Gabriel, R.9
  • 118
    • 33746405106 scopus 로고    scopus 로고
    • Neuroprotective effect of PACAP against kainic acid (KA)-induced neurotoxicity in rat retina
    • Seki, T.; Nakatani, M.; Taki, C.; Shinonara, Y.; Ozawa, M.; Nishimura, S.; Shioda, S. Neuroprotective effect of PACAP against kainic acid (KA)-induced neurotoxicity in rat retina. Ann. NY Acad. Sci. 2006, 1070, 531-534.
    • (2006) Ann. NY Acad. Sci , vol.1070 , pp. 531-534
    • Seki, T.1    Nakatani, M.2    Taki, C.3    Shinonara, Y.4    Ozawa, M.5    Nishimura, S.6    Shioda, S.7
  • 119
    • 33746467019 scopus 로고    scopus 로고
    • Involvement of ERK and CREB signalling pathways in the protective effect of PACAP on monosodium glutamate-induced retinal lesion
    • Racz, B.; Tamas, A.; Kiss, P.; Toth, G.; Gasz, B.; Borsiczky, B.; Ferencz, A.; Gallyas, F. Jr.; Roth, E.; Reglodi, D. Involvement of ERK and CREB signalling pathways in the protective effect of PACAP on monosodium glutamate-induced retinal lesion. Ann. NY Acad. Sci. 2006, 1070, 507-511.
    • (2006) Ann. NY Acad. Sci , vol.1070 , pp. 507-511
    • Racz, B.1    Tamas, A.2    Kiss, P.3    Toth, G.4    Gasz, B.5    Borsiczky, B.6    Ferencz, A.7    Gallyas Jr., F.8    Roth, E.9    Reglodi, D.10
  • 121
    • 38449103890 scopus 로고    scopus 로고
    • Effects of pituitary adenylate cyclase activating polypeptide (PACAP) on the PKA-Bad-14-3-3 signaling pathway in glutamate-induced retinal injury in neonatal rats
    • Racz, B.; Gallyas, F. Jr.; Kiss, P.; Tamas, A.; Lubics, A.; Lengvari, I.; Roth, E.; Toth, G.; Hegyi, O.; Verzar, Zs.; Fabricsek, Cs.; Reglodi D. Effects of pituitary adenylate cyclase activating polypeptide (PACAP) on the PKA-Bad-14-3-3 signaling pathway in glutamate-induced retinal injury in neonatal rats. Neurotox. Res. 2007, 12, 95-104.
    • (2007) Neurotox. Res , vol.12 , pp. 95-104
    • Racz, B.1    Gallyas Jr., F.2    Kiss, P.3    Tamas, A.4    Lubics, A.5    Lengvari, I.6    Roth, E.7    Toth, G.8    Hegyi, O.9    Verzar, Z.10    Fabricsek, C.11    Reglodi, D.12
  • 122
    • 77649226246 scopus 로고    scopus 로고
    • Evaluation of the protective effects of PACAP with cell-specific markers in ischemia-induced retinal degeneration
    • in press
    • Atlasz, T.; Szabadfi, K.; Kiss, P.; Tamas, A.; Toth, G.; Reglodi, D.; Gabriel, R. Evaluation of the protective effects of PACAP with cell-specific markers in ischemia-induced retinal degeneration. Brain Res. Bull. 2009, in press.
    • (2009) Brain Res. Bull
    • Atlasz, T.1    Szabadfi, K.2    Kiss, P.3    Tamas, A.4    Toth, G.5    Reglodi, D.6    Gabriel, R.7
  • 123
    • 0036733355 scopus 로고    scopus 로고
    • The therapeutic potential of poly(ADPribose) polymerase inhibitors
    • Virag, L.; Szabo, C. The therapeutic potential of poly(ADPribose) polymerase inhibitors. Pharmacol. Rev. 2002, 54, 375-429.
    • (2002) Pharmacol. Rev , vol.54 , pp. 375-429
    • Virag, L.1    Szabo, C.2
  • 124
    • 46749118458 scopus 로고    scopus 로고
    • Role of the peroxynitrite-poly(ADP-ribose) polymerase pathway in human disease
    • Pacher, P.; Szabo, C. Role of the peroxynitrite-poly(ADP-ribose) polymerase pathway in human disease. Am. J. Pathol. 2008, 173, 2-13.
    • (2008) Am. J. Pathol , vol.173 , pp. 2-13
    • Pacher, P.1    Szabo, C.2
  • 125
    • 0034987156 scopus 로고    scopus 로고
    • Effect of poly(ADP-ribose) polymerase inhibitors on the ischemia-reperfusion- induced oxidative cell damage and mitochondrial metabolism in Langendorff heart perfusion system
    • Halmosi, R.; Berente, Z.; Osz, E.; Toth, K.; Literati-Nagy, P.; Sumegi, B. Effect of poly(ADP-ribose) polymerase inhibitors on the ischemia-reperfusion- induced oxidative cell damage and mitochondrial metabolism in Langendorff heart perfusion system. Mol. Pharmacol. 2001, 59, 1497-1505.
    • (2001) Mol. Pharmacol , vol.59 , pp. 1497-1505
    • Halmosi, R.1    Berente, Z.2    Osz, E.3    Toth, K.4    Literati-Nagy, P.5    Sumegi, B.6
  • 126
    • 2142694340 scopus 로고    scopus 로고
    • Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling
    • Hong, S.J.; Dawson, T.M.; Dawson, V.L. Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling. Trends Pharmacol. Sci. 2004, 25, 259-264.
    • (2004) Trends Pharmacol. Sci , vol.25 , pp. 259-264
    • Hong, S.J.1    Dawson, T.M.2    Dawson, V.L.3
  • 128
    • 33646827842 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation
    • Xu, Y.; Huang, S.; Liu, Z.G.; Han, J. Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation. J. Biol. Chem. 2006, 281, 8788-8795.
    • (2006) J. Biol. Chem , vol.281 , pp. 8788-8795
    • Xu, Y.1    Huang, S.2    Liu, Z.G.3    Han, J.4
  • 129
    • 0037446371 scopus 로고    scopus 로고
    • Decrease of the inflammatory response and induction of the Akt/protein kinase B pathway by poly-(ADP-ribose) polymerase 1 inhibitor in endotoxin-induced septic shock
    • Veres, B.; Gallyas, F. Jr.; Varbiro, G.; Berente, Z.; Osz, E.; Szekeres, G.; Szabo, C.; Sumegi, B. Decrease of the inflammatory response and induction of the Akt/protein kinase B pathway by poly-(ADP-ribose) polymerase 1 inhibitor in endotoxin-induced septic shock. Biochem. Pharmacol. 2003, 65, 1373-1382.
    • (2003) Biochem. Pharmacol , vol.65 , pp. 1373-1382
    • Veres, B.1    Gallyas Jr., F.2    Varbiro, G.3    Berente, Z.4    Osz, E.5    Szekeres, G.6    Szabo, C.7    Sumegi, B.8
  • 130
    • 0034903405 scopus 로고    scopus 로고
    • Increased expression and activation of poly(ADP-ribose) polymerase (PARP) contribute to retinal ganglion cell death following rat optic nerve transection
    • Weise, J.; Isenmann, S.; Bahr, M. Increased expression and activation of poly(ADP-ribose) polymerase (PARP) contribute to retinal ganglion cell death following rat optic nerve transection. Cell Death Differ. 2001, 8, 801-807.
    • (2001) Cell Death Differ , vol.8 , pp. 801-807
    • Weise, J.1    Isenmann, S.2    Bahr, M.3
  • 131
    • 34548847441 scopus 로고    scopus 로고
    • Excessive activation of poly-(ADP-ribose) polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse
    • Paquet-Durand, F.; Silva, J.; Talukdar, T.; Johnson, L.E.; Azadi, S.; van Veen, T.; Ueffing, M.; Hauck, S.M.; Ekstrom, P.A. Excessive activation of poly-(ADP-ribose) polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse. Neurobiol. Dis. 2007, 27, 10311-10319.
    • (2007) Neurobiol. Dis , vol.27 , pp. 10311-10319
    • Paquet-Durand, F.1    Silva, J.2    Talukdar, T.3    Johnson, L.E.4    Azadi, S.5    van Veen, T.6    Ueffing, M.7    Hauck, S.M.8    Ekstrom, P.A.9
  • 132
    • 37349109987 scopus 로고    scopus 로고
    • Oxidative-induced apoptosis to an immortalized ganglion cell line is caspase independent but involves the activation of poly (ADP-ribose) polymerase and apoptosisinducing factor
    • Li, G.Y.; Osborne, N.N. Oxidative-induced apoptosis to an immortalized ganglion cell line is caspase independent but involves the activation of poly (ADP-ribose) polymerase and apoptosisinducing factor. Brain Res. 2008, 1188, 35-43.
    • (2008) Brain Res , vol.1188 , pp. 35-43
    • Li, G.Y.1    Osborne, N.N.2
  • 133
    • 33748068133 scopus 로고    scopus 로고
    • Blockade of PARP activity attenuates poly(ADP-ribosyl)ation but offers only partial neuroprotection against NMDA-induced cell death in the rat retina
    • Goebel, D.J.; Winkler, B.S. Blockade of PARP activity attenuates poly(ADP-ribosyl)ation but offers only partial neuroprotection against NMDA-induced cell death in the rat retina. J. Neurochem. 2006, 98, 1732-1745.
    • (2006) J. Neurochem , vol.98 , pp. 1732-1745
    • Goebel, D.J.1    Winkler, B.S.2
  • 134
    • 31344471292 scopus 로고    scopus 로고
    • Nicotinamide blocks N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in rats through poly (ADP-ribose) polymerase activity and Jun N-terminal kinase/activator protein-1 pathway inhibition
    • Uehara, N.; Miki, K.; Tsukamoto, R.; Matsuoka, Y.; Tsubura, A. Nicotinamide blocks N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in rats through poly (ADP-ribose) polymerase activity and Jun N-terminal kinase/activator protein-1 pathway inhibition. Exp. Eye Res. 2006, 82, 488-495.
    • (2006) Exp. Eye Res , vol.82 , pp. 488-495
    • Uehara, N.1    Miki, K.2    Tsukamoto, R.3    Matsuoka, Y.4    Tsubura, A.5
  • 135
    • 0037384802 scopus 로고    scopus 로고
    • Signaling of cell death and cell survival following focal cerebral ischemia: Life and death struggle in the penumbra
    • Ferrer, I.; Planas, A.M. Signaling of cell death and cell survival following focal cerebral ischemia: life and death struggle in the penumbra. J. Neuropathol. Exp. Neurol. 2003, 62, 329-339.
    • (2003) J. Neuropathol. Exp. Neurol , vol.62 , pp. 329-339
    • Ferrer, I.1    Planas, A.M.2
  • 137
    • 26944440480 scopus 로고    scopus 로고
    • Neuroprotective effects of KCL-440, a new poly(ADP-ribose) polymerase inhibitor, in the rat middle cerebral artery occlusion model
    • Ikeda, Y.; Hokamura, K.; Kawai, T.; Ishiyama, J.; Ishikawa, K.; Anraku, T.; Uno, T.; Umemura, K. Neuroprotective effects of KCL-440, a new poly(ADP-ribose) polymerase inhibitor, in the rat middle cerebral artery occlusion model. Brain Res. 2005, 1060, 73-80.
    • (2005) Brain Res , vol.1060 , pp. 73-80
    • Ikeda, Y.1    Hokamura, K.2    Kawai, T.3    Ishiyama, J.4    Ishikawa, K.5    Anraku, T.6    Uno, T.7    Umemura, K.8


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