Effects of ATP-sensitive potassium channel activators diazoxide and BMS-191095 on membrane potential and reactive oxygen species production in isolated piglet mitochondria

Brain Research Bulletin

Volumn 66, Issue 2, 2005, Pages 85-90

  Busija, David W ^a   Katakam, Prasad ^a   Rajapakse, Nishadi C ^a,d   Kis, Bela ^a   Grover, Gary ^b   Domoki, Ferenc ^c   Bari, Ferenc ^c  

^a WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

^b BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF SZEGED   (Hungary)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

BMS 191095; Diazoxide; Inwardly rectifying potassium channel; Ischemia; Mitochondria; Potassium channels; Succinate dehydrogenase; Sulfonylurea receptors

Indexed keywords

3 NITROPROPIONIC ACID; 5 HYDROXYDECANOIC ACID; BMS 191095; DIAZOXIDE; GLIBENCLAMIDE; INWARDLY RECTIFYING POTASSIUM CHANNEL; POTASSIUM CHANNEL; POTASSIUM CHANNEL STIMULATING AGENT; REACTIVE OXYGEN METABOLITE; SUCCINATE DEHYDROGENASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN MITOCHONDRION; CONTROLLED STUDY; DRUG EFFECT; DRUG SELECTIVITY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; SWINE;

ADENOSINE TRIPHOSPHATE; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; BENZOPYRANS; DECANOIC ACIDS; DIAZOXIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; GLYBURIDE; HYDROXY ACIDS; IMIDAZOLES; MEMBRANE POTENTIALS; MITOCHONDRIA; ORGANOMETALLIC COMPOUNDS; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; REACTIVE OXYGEN SPECIES; SWINE; TIME FACTORS;

EID: 20744453559     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2005.03.022     Document Type: Article

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