Suppression of ganglion cell death by PACAP following optic nerve transection in the rat

Journal of Molecular Neuroscience

Volumn 36, Issue 1-3, 2008, Pages 57-60

  Seki, Tamotsu ^a,b   Itoh, Hiroyuki ^b,c   Nakamachi, Tomoya ^b   Shioda, Seiji ^b  

^a Tamagawa Eye Clinic   (Japan)

^b SHOWA UNIVERSITY   (Japan)

^c Kozawa Eye Hospital   (Japan)

Author keywords

Apoptosis; Ganglion cell; Glaucoma; Neurotrophic factor; PACAP; Transection of optic nerve

Indexed keywords

HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL COUNT; CELL DEATH; CONTROLLED STUDY; DRUG EFFECT; MALE; NERVE TRANSECTION; NEUROPROTECTION; NONHUMAN; RAT; RETINA GANGLION CELL;

ANIMALS; CELL DEATH; CELL SURVIVAL; MALE; OPTIC NERVE; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RATS; RATS, WISTAR; RETINAL GANGLION CELLS;

ANIMALIA; OVIS; RATTUS;

EID: 58149085967     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12031-008-9091-5     Document Type: Article

References (18)

1. A. Arimura 1998 Perspectives on pituitary adenylate cyclase activating polypeptide (PACAP) in the neuroendocrine, endocrine, and nervous systems Japanese Journal of Physiology 48 301 331 doi:10.2170/jjphysiol.48.301
2. H. Atluri A. K. Mitra 2003 Disposition of short-chain aliphatic alcohols in rabbit vitreous by ocular microdialysis Experimental Eye Research 76 3 315 320 March
3. M. Li C. David 2005 Signaling cascades involved in neuroprotection by subpicomolar pituitary adenylate cyclase-activating polypeptide 38 Journal of Molecular Neuroscience 27 1 91 105 doi:10.1385/JMN:27:1:091
4. S. Mansour-Robaey D. B. Clarke Y. C. Wang G. M. Bray A. J. Aguayo 1994 Effects of ocular injury and administration of brain-derived neurotrophic factor on survival and regrowth of axotomized retinal ganglion cells Proceedings of the National Academy of Sciences of the United States of America 91 5 1632 1636 doi:10.1073/pnas.91.5.1632
5. A. Miyata A. Arimura R. Dahl 1989 Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells Biochemical And Biophysical Research Communications 164 1 567 574 doi:10.1016/0006-291X(89)91757-9
6. M. Nakatani T. Seki Y. Shinohara 2006 Pituitary adenylate cyclase-activating peptide (PACAP) stimulates production of interleukin-6 in rat Muller cells Peptides 27 7 1871 1876 July
7. S. F. Nilsson P. De Neef P. Robberecht 1994 Characterization of ocular receptors for pituitary adenylate cyclase activating polypeptide (PACAP) and their coupling to adenylate cyclase Experimental Eye Research 58 4 459 467 doi:10.1006/exer.1994.1039
8. H. Ohtaki T. Nakamachi K. Dohi 2006 Pituitary adenylate cyclase-activating polypeptide (PACAP) decreases ischemic neuronal cell death in association with IL-6 Proceedings of the National Academy of Sciences of the United States of America 103 19 7488 7493
9. H. A. Quigley R. W. Nickells L. A. Kerrigan 1995 Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis Investigative Ophthalmology & Visual Science 36 5 774 786
10. D. Reglodi A. Tamás 2002 Effects of pretreatment with PACAP on the infarct size and functional outcome in rat permanent focal cerebral ischemia Peptides 23 12 2227 2234 December
11. T. Seki S. Izumi S. Shioda A. Arimura 2000 Electron microscopic observation of pituitary adenylate cyclase-activating polypeptide (PACAP)-containing in the rat retina Peptides 21 109 113 doi:10.1016/S0196- 9781(99)00180-1
12. T. Seki S. Izumi C. -J. Zhou 2000 Gene expression for PACAP receptor mRNA in the Rat Retina by in situ hybridization and in situ RT-PCR Annals of the New York Academy of Sciences 921 366 369
13. T. Seki M. Nakatani C. Taki 2006 Neuroprotective effect of PACAP against kainic acid-induced neurotoxicity in rat retina Annals of the New York Academy of Sciences 1070 531 534 doi:10.1196/annals.1317.074
14. T. Seki Y. Shinohara C. Taki M. Nakatani 2006 PACAP stimulates the release of interleukin-6 in cultured rat Müller cells Annals of the New York Academy of Sciences 1070 535 539 July
15. S. Shioda H. Ohtaki T. Nakamachi 2006 Pleiotropic functions of PACAP in the CNS: neuroprotection and neurodevelopment Annals of the New York Academy of Sciences 1070 550 560 doi:10.1196/annals.1317.080
16. S. Shioda H. Ozawa K. Dohi 1998 PACAP protects hippocampal neurons against apoptosis: involvement of JNK/SAPK signaling pathway Annals of the New York Academy of Sciences 865 111 117 doi:10.1111/j.1749-6632.1998.tb11169.x
17. J. Xu J. J. Heys V. H. Barocas 2000 Permeability and diffusion in vitreous humor: implications for drug delivery Pharmaceutical Research 17 6 664 669 June
18. T. Yoshitomi K. Yamaji H. Ishikawa 2002 Effect of pituitary adenylate cyclase-activating peptide on isolated rabbit iris sphincter and dilator muscles Investigative Ophthalmology & Visual Science 43 3 780 783