The role of the funny current in pacemaker activity

Circulation Research

Volumn 106, Issue 3, 2010, Pages 434-446

  Difrancesco, Dario ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Funny current; HCN channels; Pacemaking; Rate modulation; Sinoatrial node

Indexed keywords

4 (N ETHYL N PHENYLAMINO) 1,2 DIMETHYL 6 (METHYLAMINO)PYRIMIDINIUM CHLORIDE; ACETYLCHOLINE; ADRENALIN; ALINIDINE; BETA ADRENERGIC RECEPTOR; BIOLOGICAL MARKER; CLONIDINE; CYCLIC AMP; CYCLIC NUCLEOTIDE GATED CHANNEL; FALIPAMIL; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CHANNEL 4; IVABRADINE; MUSCARINIC M2 RECEPTOR; PROPOFOL; UNCLASSIFIED DRUG; ZATEBRADINE;

BETA ADRENERGIC STIMULATION; CARDIOTOXICITY; CHOLINERGIC STIMULATION; CHRONIC DISEASE; DIASTOLIC DEPOLARIZATION; DRUG MECHANISM; FUNNY CURRENT; HEART DEPOLARIZATION; HEART MUSCLE CELL; HEART RATE; HUMAN; ION CURRENT; LOSS OF FUNCTION MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; SINUS BRADYCARDIA; SINUS NODE; SINUS NODE MEMBRANE POTENTIAL; STABLE ANGINA PECTORIS; TREATMENT RESPONSE; VISUAL DISORDER;

ACTION POTENTIALS; ANIMALS; BENZAZEPINES; CYCLIC AMP; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; HEART CONDUCTION SYSTEM; HEART RATE; HUMANS; ION CHANNELS; MUSCLE PROTEINS; PHOSPHORYLATION; POTASSIUM; POTASSIUM CHANNELS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTOR, MUSCARINIC M2; RECEPTORS, ADRENERGIC, BETA; RYANODINE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SINOATRIAL NODE; SODIUM;

EID: 77649123846     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.109.208041     Document Type: Review

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