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Volumn 47, Issue 4, 2000, Pages 658-687

The sinoatrial node, a heterogeneous pacemaker structure

Author keywords

Gap junctions; Ion channels; Sinus node

Indexed keywords

CONNEXIN 40; CONNEXIN 43; CONNEXIN 45; GAP JUNCTION PROTEIN; ION CHANNEL;

EID: 0033847605     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(00)00135-8     Document Type: Review
Times cited : (597)

References (193)
  • 2
    • 0022634753 scopus 로고
    • Structure and function of the sino-atrial node: A review
    • Bouman L.N., Jongsma H.J. Structure and function of the sino-atrial node: a review. Eur Heart J. 7:1986;94-104.
    • (1986) Eur Heart J , vol.7 , pp. 94-104
    • Bouman, L.N.1    Jongsma, H.J.2
  • 4
    • 0023677594 scopus 로고
    • The mammalian sinoatrial node
    • Opthof T. The mammalian sinoatrial node. Cardiovasc Drugs Ther. 1:1988;573-597.
    • (1988) Cardiovasc Drugs Ther , vol.1 , pp. 573-597
    • Opthof, T.1
  • 5
    • 0027509511 scopus 로고
    • Cardiac pacemaking in the sino-atrial node
    • Irisawa H., Brown H.F., Giles W. Cardiac pacemaking in the sino-atrial node. Physiol Rev. 73:1993;197-227.
    • (1993) Physiol Rev , vol.73 , pp. 197-227
    • Irisawa, H.1    Brown, H.F.2    Giles, W.3
  • 10
    • 0001765987 scopus 로고
    • Anatomy of the human sinus node
    • James T.N. Anatomy of the human sinus node. Anat Rec. 141:1961;109-139.
    • (1961) Anat Rec , vol.141 , pp. 109-139
    • James, T.N.1
  • 11
    • 15444346700 scopus 로고    scopus 로고
    • The architecture of the sinus node, the atrioventricular conduction axis, and the internodal atrial myocadium
    • Anderson R.H., Ho S.Y. The architecture of the sinus node, the atrioventricular conduction axis, and the internodal atrial myocadium. J Cardiovasc Electrophysiol. 9:1998;1233-1248.
    • (1998) J Cardiovasc Electrophysiol , vol.9 , pp. 1233-1248
    • Anderson, R.H.1    Ho, S.Y.2
  • 13
    • 0021854735 scopus 로고
    • Functional and morphological organization of the guinea-pig sinoatrial node compared with the rabbit sinoatrial node
    • Opthof T., de Jonge B., Mackaay A.J.C., et al. Functional and morphological organization of the guinea-pig sinoatrial node compared with the rabbit sinoatrial node. J Mol Cell Cardiol. 17:1985;549-564.
    • (1985) J Mol Cell Cardiol , vol.17 , pp. 549-564
    • Opthof, T.1    De Jonge, B.2    Mackaay, A.J.C.3
  • 16
    • 0025644674 scopus 로고
    • Structure and function of the simian sinoatrial node (Macaca fascicularis)
    • Alings A.M.W., Abbas R.F., de Jonge B., Bouman L.N. Structure and function of the simian sinoatrial node (Macaca fascicularis). J Mol Cell Cardiol. 22:1990;1453-1466.
    • (1990) J Mol Cell Cardiol , vol.22 , pp. 1453-1466
    • Alings, A.M.W.1    Abbas, R.F.2    De Jonge, B.3    Bouman, L.N.4
  • 17
    • 0033991776 scopus 로고    scopus 로고
    • The normal range and determinants of the intrinsic heart rate in man
    • Opthof T. The normal range and determinants of the intrinsic heart rate in man. Cardiovasc Res. 45:2000;177-184.
    • (2000) Cardiovasc Res , vol.45 , pp. 177-184
    • Opthof, T.1
  • 18
    • 0002647388 scopus 로고
    • Anatomy of the conduction tissues and accessory atrioventricular connections
    • D.P. Zipes, & J. Jalife. Philadelphia: W.B. Saunders
    • Anderson R.H., Becker A.E. Anatomy of the conduction tissues and accessory atrioventricular connections. Zipes D.P., Jalife J. Cardiac electrophysiology from cell to bedside. 1990;240-248 W.B. Saunders, Philadelphia.
    • (1990) Cardiac Electrophysiology from Cell to Bedside , pp. 240-248
    • Anderson, R.H.1    Becker, A.E.2
  • 20
    • 0017143804 scopus 로고
    • Spontaneous action potentials of cells in the canine sinus node
    • Woods W.M., Urthaler F., James T.N. Spontaneous action potentials of cells in the canine sinus node. Circ Res. 39:1976;76-82.
    • (1976) Circ Res , vol.39 , pp. 76-82
    • Woods, W.M.1    Urthaler, F.2    James, T.N.3
  • 21
    • 0027321780 scopus 로고
    • Immunohistochemical delineation of the conduction system. I: The sinoatrial node
    • Oosthoek P.W., Viragh S., Mayen A.E.M., et al. Immunohistochemical delineation of the conduction system. I: the sinoatrial node. Circ Res. 73:1993;473-481.
    • (1993) Circ Res , vol.73 , pp. 473-481
    • Oosthoek, P.W.1    Viragh, S.2    Mayen, A.E.M.3
  • 22
    • 0029144338 scopus 로고
    • Primary negativity does not predict dominant pacemaker location: Implications for sinoatrial conduction
    • Bromberg B.I., Hand D.E., Schuessler R.B., Boineau J.P. Primary negativity does not predict dominant pacemaker location: implications for sinoatrial conduction. Am J Physiol. 269:1995;H877-H887.
    • (1995) Am J Physiol , vol.269 , pp. 877-H887
    • Bromberg, B.I.1    Hand, D.E.2    Schuessler, R.B.3    Boineau, J.P.4
  • 23
    • 0023029058 scopus 로고
    • Propagation through electrically coupled cells: How a small SA node drives a large atrium
    • Joyner R.W., van Capelle F.J.L. Propagation through electrically coupled cells: how a small SA node drives a large atrium. Biophys J. 50:1986;1157-1164.
    • (1986) Biophys J , vol.50 , pp. 1157-1164
    • Joyner, R.W.1    Van Capelle, F.J.L.2
  • 24
    • 0033033946 scopus 로고    scopus 로고
    • Connexin45, a major connexin of the rabbit sinoatrial node, is co-expressed with connexin43 in a restricted zone at the nodal-crista terminalis border
    • Coppen S.R., Kodama I., Boyett M.R., et al. Connexin45, a major connexin of the rabbit sinoatrial node, is co-expressed with connexin43 in a restricted zone at the nodal-crista terminalis border. J Histochem Cytochem. 47:1999;907-918.
    • (1999) J Histochem Cytochem , vol.47 , pp. 907-918
    • Coppen, S.R.1    Kodama, I.2    Boyett, M.R.3
  • 26
    • 0013932370 scopus 로고
    • Comparative ultrastructure of the sinus node in man and dog
    • James T.N., Sherf L., Fine G., Morales A.R. Comparative ultrastructure of the sinus node in man and dog. Circulation. 34:1966;139-163.
    • (1966) Circulation , vol.34 , pp. 139-163
    • James, T.N.1    Sherf, L.2    Fine, G.3    Morales, A.R.4
  • 27
    • 0025730285 scopus 로고
    • Mathematical model of geometry and fibrous structure of the heart
    • Nielsen P.M.F., Le Grice I.J., Smaill B.H., Hunter P.J. Mathematical model of geometry and fibrous structure of the heart. Am J Physiol. 260:1991;H1365-H1378.
    • (1991) Am J Physiol , vol.260 , pp. 1365-H1378
    • Nielsen, P.M.F.1    Le Grice, I.J.2    Smaill, B.H.3    Hunter, P.J.4
  • 28
    • 0021350522 scopus 로고
    • Pacemaker cell types in the rabbit sinus node: A correlative ultrastructural and electrophysiological study
    • Masson-Pévet M.A., Bleeker W.K., Besselsen E., et al. Pacemaker cell types in the rabbit sinus node: a correlative ultrastructural and electrophysiological study. J Mol Cell Cardiol. 16:1984;53-63.
    • (1984) J Mol Cell Cardiol. , vol.16 , pp. 53-63
    • Masson-Pévet, M.A.1    Bleeker, W.K.2    Besselsen, E.3
  • 29
    • 0032574637 scopus 로고    scopus 로고
    • Distribution of atrial and nodal cells within rabbit sinoatrial node. Models of sinoatrial transition
    • Verheijck E.E., Wessels A., van Ginneken A.C.G., et al. Distribution of atrial and nodal cells within rabbit sinoatrial node. Models of sinoatrial transition. Circulation. 97:1998;1623-1631.
    • (1998) Circulation , vol.97 , pp. 1623-1631
    • Verheijck, E.E.1    Wessels, A.2    Van Ginneken, A.C.G.3
  • 30
    • 0025082937 scopus 로고
    • Rabbit sino-atrial node cells: Isolation and electrophysiological properties
    • Denyer J.C., Brown H.F. Rabbit sino-atrial node cells: isolation and electrophysiological properties. J Physiol. 428:1990;405-424.
    • (1990) J Physiol , vol.428 , pp. 405-424
    • Denyer, J.C.1    Brown, H.F.2
  • 32
    • 0015914673 scopus 로고
    • Electrotonic spread in the sinoatrial node of the rabbit heart
    • Bonke F.I.M. Electrotonic spread in the sinoatrial node of the rabbit heart. Pflüger's Arch. 339:1973;17-23.
    • (1973) Pflüger's Arch , vol.339 , pp. 17-23
    • Bonke, F.I.M.1
  • 33
    • 0342838313 scopus 로고
    • Electrical cell coupling in rabbit sinoatrial node and atrium. Experimental and theoretical evaluation
    • L.N. Bouman, & H.J. Jongsma. The Hague: Martinus Nijhoff
    • Bukauskas F.F., Gutman A.M., Kisunas K.J., Veteikis R.P. Electrical cell coupling in rabbit sinoatrial node and atrium. Experimental and theoretical evaluation. Bouman L.N., Jongsma H.J. Cardiac rate and rhythm. 1982;195-214 Martinus Nijhoff, The Hague.
    • (1982) Cardiac Rate and Rhythm , pp. 195-214
    • Bukauskas, F.F.1    Gutman, A.M.2    Kisunas, K.J.3    Veteikis, R.P.4
  • 34
    • 0020381697 scopus 로고
    • Asymmetry of the sino-atrial conduction in the rabbit heart
    • Bleeker W.K., Mackaay A.J.C., Masson-Pevet M., et al. Asymmetry of the sino-atrial conduction in the rabbit heart. J Mol Cell Cardiol. 14:1982;633-643.
    • (1982) J Mol Cell Cardiol , vol.14 , pp. 633-643
    • Bleeker, W.K.1    Mackaay, A.J.C.2    Masson-Pevet, M.3
  • 35
    • 0017264346 scopus 로고
    • Characteristics of the rectifying properties of the sinoatrial node cell of the rabbit
    • Seyama I. Characteristics of the rectifying properties of the sinoatrial node cell of the rabbit. J Physiol. 255:1976;379-397.
    • (1976) J Physiol , vol.255 , pp. 379-397
    • Seyama, I.1
  • 36
    • 0015914748 scopus 로고
    • Passive electrical properties of atrial fibers of the rabbit heart
    • Bonke F.I.M. Passive electrical properties of atrial fibers of the rabbit heart. Pflüger's Arch. 339:1973;1-15.
    • (1973) Pflüger's Arch , vol.339 , pp. 1-15
    • Bonke, F.I.M.1
  • 37
    • 0028373583 scopus 로고
    • Gap junctions in the sinoatrial node: Immunohistochemical localization and correlation with activation patterns
    • Opthof T. Gap junctions in the sinoatrial node: immunohistochemical localization and correlation with activation patterns. J Cardiovasc Electrophysiol. 5:1994;138-143.
    • (1994) J Cardiovasc Electrophysiol , vol.5 , pp. 138-143
    • Opthof, T.1
  • 38
    • 0018581233 scopus 로고
    • The plasma membrane of leading pacemaker cells in the rabbit sinus node: A quantitative ultrastructural analysis
    • Masson-Pévet M.A., Bleeker W.K., Gros D. The plasma membrane of leading pacemaker cells in the rabbit sinus node: A quantitative ultrastructural analysis. Circ Res. 45:1979;621-629.
    • (1979) Circ Res , vol.45 , pp. 621-629
    • Masson-Pévet, M.A.1    Bleeker, W.K.2    Gros, D.3
  • 39
    • 0025159130 scopus 로고
    • The cardiac gap junctions and intercalated disc
    • Severs N.J. The cardiac gap junctions and intercalated disc. Int J Cardiol. 26:1990;137-173.
    • (1990) Int J Cardiol , vol.26 , pp. 137-173
    • Severs, N.J.1
  • 40
    • 0026515179 scopus 로고
    • Membrane topology and quaternary structure of cardiac gap junction ion channels
    • Yeager M., Gilula N.B. Membrane topology and quaternary structure of cardiac gap junction ion channels. J Mol Biol. 223:1992;929-948.
    • (1992) J Mol Biol , vol.223 , pp. 929-948
    • Yeager, M.1    Gilula, N.B.2
  • 41
    • 0342838312 scopus 로고    scopus 로고
    • Connexins, connexons and intercellular communication
    • Goodenough D.A., Goliger J.A., Paul D.L. Connexins, connexons and intercellular communication. Annu Rev Biochem. 77:1996;1156-1163.
    • (1996) Annu Rev Biochem , vol.77 , pp. 1156-1163
    • Goodenough, D.A.1    Goliger, J.A.2    Paul, D.L.3
  • 42
    • 0026604627 scopus 로고
    • Cardiac myocytes express multiple gp junction proteins
    • Kanter H.L., Saffitz J.E., Beyer E.C. Cardiac myocytes express multiple gp junction proteins. Circ Res. 70:1992;438-444.
    • (1992) Circ Res , vol.70 , pp. 438-444
    • Kanter, H.L.1    Saffitz, J.E.2    Beyer, E.C.3
  • 43
    • 0027409355 scopus 로고
    • Molecular cloning and functional expression of human connexin37, an endothelial cell gap junction protein
    • Reed K.E., Westphale E.M., Larson D.M., et al. Molecular cloning and functional expression of human connexin37, an endothelial cell gap junction protein. J Clin Invest. 91:1993;997-1004.
    • (1993) J Clin Invest , vol.91 , pp. 997-1004
    • Reed, K.E.1    Westphale, E.M.2    Larson, D.M.3
  • 44
    • 0026541187 scopus 로고
    • Four novel members of the connexin family of gap junction proteins
    • Haefliger J.-A., Bruzzone R., Jenkins N.A., et al. Four novel members of the connexin family of gap junction proteins. J Biol Chem. 267:1992;2052-2064.
    • (1992) J Biol Chem , vol.267 , pp. 2052-2064
    • Haefliger, J.-A.1    Bruzzone, R.2    Jenkins, N.A.3
  • 45
    • 0028784986 scopus 로고
    • Selectivity of connexin-specific gap junctions does not correlate with channel conductance
    • Veenstra R.D., Wang H.-Z., Beblo D.A., et al. Selectivity of connexin-specific gap junctions does not correlate with channel conductance. Circ Res. 77:1995;1156-1165.
    • (1995) Circ Res , vol.77 , pp. 1156-1165
    • Veenstra, R.D.1    Wang, H.-Z.2    Beblo, D.A.3
  • 46
    • 0026693725 scopus 로고
    • Multiple connexins confer distinct regulatory and conductance properties of gap junctions in developing heart
    • Veenstra R.D., Wang H.-Z., Westphale E.M., Beyer E.C. Multiple connexins confer distinct regulatory and conductance properties of gap junctions in developing heart. Circ Res. 71:1992;1277-1283.
    • (1992) Circ Res , vol.71 , pp. 1277-1283
    • Veenstra, R.D.1    Wang, H.-Z.2    Westphale, E.M.3    Beyer, E.C.4
  • 47
    • 0025729509 scopus 로고
    • Spatial distribution of connexin43, the major gap junction protein in the developing and adult rat heart
    • van Kempen M.J.A., Fromaget C., Gross D., Moorman A.F.M., Lamers W.H. Spatial distribution of connexin43, the major gap junction protein in the developing and adult rat heart. Circ Res. 68:1991;1638-1651.
    • (1991) Circ Res , vol.68 , pp. 1638-1651
    • Van Kempen, M.J.A.1    Fromaget, C.2    Gross, D.3    Moorman, A.F.M.4    Lamers, W.H.5
  • 48
    • 0025828788 scopus 로고
    • Gap junction distribution in adult mammalian myocardium revealed by an anti-peptide antibody and laser scanning confocal microscopy
    • Gourdie R.G., Green C.R., Severs N.J. Gap junction distribution in adult mammalian myocardium revealed by an anti-peptide antibody and laser scanning confocal microscopy. J Cell Science. 99:1991;41-55.
    • (1991) J Cell Science , vol.99 , pp. 41-55
    • Gourdie, R.G.1    Green, C.R.2    Severs, N.J.3
  • 49
    • 0032498522 scopus 로고    scopus 로고
    • Connexin45 expression is preferentially associated with the ventricular conduction system in mouse and rat heart
    • Coppen S.R., Dupont E., Rothery S., Severs N.J. Connexin45 expression is preferentially associated with the ventricular conduction system in mouse and rat heart. Circ Res. 82:1998;232-243.
    • (1998) Circ Res , vol.82 , pp. 232-243
    • Coppen, S.R.1    Dupont, E.2    Rothery, S.3    Severs, N.J.4
  • 50
    • 0028024953 scopus 로고
    • Distinct gap junction protein phenotypes in cardiac tissues with disparate conduction properties
    • Davies L.M., Kanter H.L., Beyer E.C., Saffitz J.E. Distinct gap junction protein phenotypes in cardiac tissues with disparate conduction properties. J Am Coll Cardiol. 24:1994;1124-1132.
    • (1994) J Am Coll Cardiol , vol.24 , pp. 1124-1132
    • Davies, L.M.1    Kanter, H.L.2    Beyer, E.C.3    Saffitz, J.E.4
  • 51
    • 0027218911 scopus 로고
    • The spatial distribution and relative abundance of gap-junctional connexin40 correlate to functional properties of components of the cardiac atrioventricular conduction system
    • Gourdie R.G., Severs N.J., Green C.R., et al. The spatial distribution and relative abundance of gap-junctional connexin40 correlate to functional properties of components of the cardiac atrioventricular conduction system. J Cell Sci. 105:1993;985-991.
    • (1993) J Cell Sci , vol.105 , pp. 985-991
    • Gourdie, R.G.1    Severs, N.J.2    Green, C.R.3
  • 52
    • 0026635428 scopus 로고
    • Gap junctional channels in adult mammalian sinus nodal cells. Immunolocalization and electrophysiology
    • Anumonwo J.M.B., Wang H.-Z., Trabka-Janik E., et al. Gap junctional channels in adult mammalian sinus nodal cells. Immunolocalization and electrophysiology. Circ Res. 71:1992;229-239.
    • (1992) Circ Res , vol.71 , pp. 229-239
    • Anumonwo, J.M.B.1    Wang, H.-Z.2    Trabka-Janik, E.3
  • 53
    • 0027954335 scopus 로고
    • Immunohistochemical localization of gap junction protein channels in hamster sinoatrial node in correlation with electrophysiologic mapping of the pacemaker region
    • Trabka-Janik E., Cooms W., Lemanski L.F., Delmer M., Jalife J. Immunohistochemical localization of gap junction protein channels in hamster sinoatrial node in correlation with electrophysiologic mapping of the pacemaker region. J Cardiovasc Electrophysiol. 5:1994;125-127.
    • (1994) J Cardiovasc Electrophysiol , vol.5 , pp. 125-127
    • Trabka-Janik, E.1    Cooms, W.2    Lemanski, L.F.3    Delmer, M.4    Jalife, J.5
  • 55
    • 0013592412 scopus 로고
    • Distribution of the cardiac gap junction protein, connexin43 in the neonatal and adult human heart
    • G. Marechal, & U. Carraro. Proceedings of XIXth European Conference, Brussels. Andover, UK: Intercept
    • Oosthoek P.W., van Kempen M.J.A., Wessels A., Lamers W.H., Moorman A.F.M. Distribution of the cardiac gap junction protein, connexin43 in the neonatal and adult human heart. Marechal G., Carraro U. Muscle and motility. Proceedings of XIXth European Conference, Brussels :1990;85-90 Intercept, Andover, UK.
    • (1990) Muscle and Motility , pp. 85-90
    • Oosthoek, P.W.1    Van Kempen, M.J.A.2    Wessels, A.3    Lamers, W.H.4    Moorman, A.F.M.5
  • 57
    • 0028939978 scopus 로고
    • Spatial distribution of connexin43, the major cardiac gap junction protein, visualizes the cellular network for impulse propagation from sinoatrial node to atrium
    • ten Velde I., de Jonge B., Verheijck E.E., et al. Spatial distribution of connexin43, the major cardiac gap junction protein, visualizes the cellular network for impulse propagation from sinoatrial node to atrium. Circ Res. 76:1995;802-811.
    • (1995) Circ Res , vol.76 , pp. 802-811
    • Ten Velde, I.1    De Jonge, B.2    Verheijck, E.E.3
  • 58
    • 0028361763 scopus 로고
    • Effects of gap junction conductance on dynamics of sinoatrial node cells: Two cell and large scale networks
    • Cai D., Winslow R.L., Noble D. Effects of gap junction conductance on dynamics of sinoatrial node cells: two cell and large scale networks. IEEE Trans Biomed Eng. 41:1994;217-231.
    • (1994) IEEE Trans Biomed Eng , vol.41 , pp. 217-231
    • Cai, D.1    Winslow, R.L.2    Noble, D.3
  • 59
    • 0031907514 scopus 로고    scopus 로고
    • Pacemaker synchronization of electrically coupled rabbit sinoatrial node cells
    • Verheijck E.E., Wilders R., Joyner R.W., et al. Pacemaker synchronization of electrically coupled rabbit sinoatrial node cells. J Gen Physiol. 111:1998;95-112.
    • (1998) J Gen Physiol , vol.111 , pp. 95-112
    • Verheijck, E.E.1    Wilders, R.2    Joyner, R.W.3
  • 60
    • 0032559833 scopus 로고    scopus 로고
    • Differential expression of gap junction proteins in the canine sinus node
    • Kwong K.F., Schuessler R.B., Green K.G., et al. Differential expression of gap junction proteins in the canine sinus node. Circ Res. 82:1998;604-612.
    • (1998) Circ Res , vol.82 , pp. 604-612
    • Kwong, K.F.1    Schuessler, R.B.2    Green, K.G.3
  • 61
    • 0032146658 scopus 로고    scopus 로고
    • Low frequency extracellular potentials recorded from the sinoatrial node
    • Yamamoto M., Honjo H., Niwa R., Kodama I. Low frequency extracellular potentials recorded from the sinoatrial node. Cardiovasc Res. 39:1998;360-372.
    • (1998) Cardiovasc Res , vol.39 , pp. 360-372
    • Yamamoto, M.1    Honjo, H.2    Niwa, R.3    Kodama, I.4
  • 62
    • 33746841128 scopus 로고
    • Electrophysiological study of the two main pacemaker mechanisms in the rabbit sinus node
    • Kreitner D. Electrophysiological study of the two main pacemaker mechanisms in the rabbit sinus node. Cardiovasc Res. 19:1985;304-318.
    • (1985) Cardiovasc Res , vol.19 , pp. 304-318
    • Kreitner, D.1
  • 63
    • 0031754508 scopus 로고    scopus 로고
    • Regional differences in the effects of 4-aminopyridine within the sinoatrial node
    • Boyett M.R., Honjo H., Yamamoto M., et al. Regional differences in the effects of 4-aminopyridine within the sinoatrial node. Am J Physiol. 275:1998;H1158-H1168.
    • (1998) Am J Physiol , vol.275 , pp. 1158-H1168
    • Boyett, M.R.1    Honjo, H.2    Yamamoto, M.3
  • 64
    • 0021198861 scopus 로고
    • Comparison between intracellular and extracellular direct current recordings of sinus node activity for evaluation of sinoatrial conduction time
    • Haberl R., Steinbeck G., Luderitz B. Comparison between intracellular and extracellular direct current recordings of sinus node activity for evaluation of sinoatrial conduction time. Circulation. 70:1984;760-767.
    • (1984) Circulation , vol.70 , pp. 760-767
    • Haberl, R.1    Steinbeck, G.2    Luderitz, B.3
  • 65
    • 0033049918 scopus 로고    scopus 로고
    • A downward gradient in action potential duration along the conduction path in and around the sinoatrial node
    • Boyett M.R., Honjo H., Yamamoto M., et al. A downward gradient in action potential duration along the conduction path in and around the sinoatrial node. Am J Physiol. 276:1999;H686-H698.
    • (1999) Am J Physiol , vol.276 , pp. 686-H698
    • Boyett, M.R.1    Honjo, H.2    Yamamoto, M.3
  • 66
    • 0020515269 scopus 로고
    • Little-excitable transitional cells in the rabbit sinoatrial node: A statistical, morphological and electrophysiological study
    • Op't Hof T., Bleeker W.K., Masson-Pévet M., Jongsma H.J., Bouman L.N. Little-excitable transitional cells in the rabbit sinoatrial node: a statistical, morphological and electrophysiological study. Experientia. 39:1983;1099-1101.
    • (1983) Experientia , vol.39 , pp. 1099-1101
    • Op't Hof, T.1    Bleeker, W.K.2    Masson-Pévet, M.3    Jongsma, H.J.4    Bouman, L.N.5
  • 67
    • 0032897508 scopus 로고    scopus 로고
    • Regional differences in the effects of E-4031 within the sinoatrial node
    • Kodama I., Boyett M.R., Nikmaram M.R., et al. Regional differences in the effects of E-4031 within the sinoatrial node. Am J Physiol. 276:1999;H793-H802.
    • (1999) Am J Physiol , vol.276 , pp. 793-H802
    • Kodama, I.1    Boyett, M.R.2    Nikmaram, M.R.3
  • 68
    • 0023640529 scopus 로고
    • Functional morphology of the mammalian sinuatrial node
    • Opthof T., de Jonge B., Jongsma H.J., Bouman L.N. Functional morphology of the mammalian sinuatrial node. Eur Heart J. 8:1987;1249-1259.
    • (1987) Eur Heart J , vol.8 , pp. 1249-1259
    • Opthof, T.1    De Jonge, B.2    Jongsma, H.J.3    Bouman, L.N.4
  • 69
    • 0021326029 scopus 로고
    • Activation sequence and potential distribution maps demonstrating multicentric atrial impulse origin in dogs
    • Boineau J.P., Miller C.B., Schuessler R.B., et al. Activation sequence and potential distribution maps demonstrating multicentric atrial impulse origin in dogs. Circ Res. 54:1984;332-347.
    • (1984) Circ Res , vol.54 , pp. 332-347
    • Boineau, J.P.1    Miller, C.B.2    Schuessler, R.B.3
  • 70
    • 0023917211 scopus 로고
    • Demonstration of a widely distributed atrial pacemaker complex in the human heart
    • Boineau J.P., Canavan T.E., Schuessler R.B., et al. Demonstration of a widely distributed atrial pacemaker complex in the human heart. Circulation. 77:1988;1221-1237.
    • (1988) Circulation , vol.77 , pp. 1221-1237
    • Boineau, J.P.1    Canavan, T.E.2    Schuessler, R.B.3
  • 71
    • 0030933634 scopus 로고    scopus 로고
    • Electrophysiologic properties of the adult human sinus node
    • Drouin E. Electrophysiologic properties of the adult human sinus node. J Cardiovasc Electrophysiol. 8:1997;254-258.
    • (1997) J Cardiovasc Electrophysiol , vol.8 , pp. 254-258
    • Drouin, E.1
  • 72
    • 0017670190 scopus 로고
    • Characteristics of extracellular potentials recorded from the sinoatrial pacemaker of the rabbit
    • Cramer M., Siegel M., Bigger T., Hoffman B.F. Characteristics of extracellular potentials recorded from the sinoatrial pacemaker of the rabbit. Circ Res. 41:1977;292-300.
    • (1977) Circ Res , vol.41 , pp. 292-300
    • Cramer, M.1    Siegel, M.2    Bigger, T.3    Hoffman, B.F.4
  • 73
    • 0018167788 scopus 로고
    • Electrograms from the canine sinoatrial pacemaker recorded in vitro and in situ
    • Cramer M., Hariman R.J., Boxer R., Hoffman B.F. Electrograms from the canine sinoatrial pacemaker recorded in vitro and in situ. Am J Cardiol. 42:1978;939-946.
    • (1978) Am J Cardiol , vol.42 , pp. 939-946
    • Cramer, M.1    Hariman, R.J.2    Boxer, R.3    Hoffman, B.F.4
  • 74
    • 0002492450 scopus 로고
    • Cellular and subcellular mechanisms of pacemaker activity initiation and synchronization in the heart
    • D.P. Zipes, & J. Jalife. Philadelphia: W.B. Saunders
    • Anumonwo J.M.B., Jalife J. Cellular and subcellular mechanisms of pacemaker activity initiation and synchronization in the heart. Zipes D.P., Jalife J. Cardiac electrophysiology. From cell to bedside. 1995;151-164 W.B. Saunders, Philadelphia.
    • (1995) Cardiac Electrophysiology. from Cell to Bedside , pp. 151-164
    • Anumonwo, J.M.B.1    Jalife, J.2
  • 75
    • 0031821666 scopus 로고    scopus 로고
    • The sinus node electrogram rediscovered
    • Hoffman B.F. The sinus node electrogram rediscovered. Cardiovasc Res. 39:1998;278-279.
    • (1998) Cardiovasc Res , vol.39 , pp. 278-279
    • Hoffman, B.F.1
  • 76
    • 0018863962 scopus 로고
    • Method for recording electrical activity of the sinoatrial node and automatic atrial foci during cardiac catheterization in human subjects
    • Hariman R.J., Krongrad E., Boxer R.A., et al. Method for recording electrical activity of the sinoatrial node and automatic atrial foci during cardiac catheterization in human subjects. Am J Cardiol. 45:1980;775-781.
    • (1980) Am J Cardiol , vol.45 , pp. 775-781
    • Hariman, R.J.1    Krongrad, E.2    Boxer, R.A.3
  • 77
    • 0019125927 scopus 로고
    • The human sinus node electrogram: A transvenous catheter technique and comparison of directly measured and indirectly estimated sinoatrial conduction time in adults
    • Reifel J.A., Gang E., Gliklich J., et al. The human sinus node electrogram: a transvenous catheter technique and comparison of directly measured and indirectly estimated sinoatrial conduction time in adults. Circulation. 62:1980;1324-1334.
    • (1980) Circulation , vol.62 , pp. 1324-1334
    • Reifel, J.A.1    Gang, E.2    Gliklich, J.3
  • 78
    • 0019935325 scopus 로고
    • The sinus node electrogram in patients with and without sick sinus syndrome: Techniques and correlation between directly measured and indirectly estimated sinoatrial conduction time
    • Gomes J.A.C., Kang P.S., El-Sherif N. The sinus node electrogram in patients with and without sick sinus syndrome: techniques and correlation between directly measured and indirectly estimated sinoatrial conduction time. Circulation. 66:1982;864-874.
    • (1982) Circulation , vol.66 , pp. 864-874
    • Gomes, J.A.C.1    Kang, P.S.2    El-Sherif, N.3
  • 79
    • 0020564254 scopus 로고
    • Persistent sinus node electrograms during abnormally prolonged postpacing atrial pauses in sick sinus syndrome in humans: Sinoatrial block vs. overdrive suppression
    • Asseman P., Berzin B., Desry D., et al. Persistent sinus node electrograms during abnormally prolonged postpacing atrial pauses in sick sinus syndrome in humans: sinoatrial block vs. overdrive suppression. Circulation. 68:1983;33-41.
    • (1983) Circulation , vol.68 , pp. 33-41
    • Asseman, P.1    Berzin, B.2    Desry, D.3
  • 80
    • 0021171668 scopus 로고
    • New application of direct sinus node recordings in man: Assessment of sinus node recovery time
    • Gomes J.A.C., Hariman R.J., Chowdry I.A. New application of direct sinus node recordings in man: assessment of sinus node recovery time. Circulation. 70:1984;663-671.
    • (1984) Circulation , vol.70 , pp. 663-671
    • Gomes, J.A.C.1    Hariman, R.J.2    Chowdry, I.A.3
  • 81
    • 0021873394 scopus 로고
    • Sinus node electrograms in patients with the hypersensitive carotid sinus syndrome
    • Gang E.S., Oseran D.S., Mandel W.J., Peter T. Sinus node electrograms in patients with the hypersensitive carotid sinus syndrome. J Am Coll Cardiol. 5:1985;1484-1490.
    • (1985) J Am Coll Cardiol , vol.5 , pp. 1484-1490
    • Gang, E.S.1    Oseran, D.S.2    Mandel, W.J.3    Peter, T.4
  • 82
    • 0023078210 scopus 로고
    • The origins of the sinus node pacemaker complex in man: Demonstration of dominant and subsidiary foci
    • Gomes J.A., Winters S.L. The origins of the sinus node pacemaker complex in man: demonstration of dominant and subsidiary foci. J Am Coll Cardiol. 9:1987;45-52.
    • (1987) J Am Coll Cardiol , vol.9 , pp. 45-52
    • Gomes, J.A.1    Winters, S.L.2
  • 84
    • 0002029042 scopus 로고
    • Sinus node dysfunction: Pathophysiology, clinical features, evaluation, and treatment
    • D.P. Zipes, & J. Jalife. Philadelphia: W.B. Saunders
    • Benditt D.G., Sakaguchi S., Goldstein M.A., et al. Sinus node dysfunction: pathophysiology, clinical features, evaluation, and treatment. Zipes D.P., Jalife J. Cardiac electrophysiology: from cell to bedside. 1995;1215-1247 W.B. Saunders, Philadelphia.
    • (1995) Cardiac Electrophysiology: From Cell to Bedside , pp. 1215-1247
    • Benditt, D.G.1    Sakaguchi, S.2    Goldstein, M.A.3
  • 85
    • 0030901476 scopus 로고    scopus 로고
    • A novel method for non-fluoroscoic catheter-based electroanatomical mapping of the heart. In vitro and in vivo accuracy results
    • Gepstein L., Hayam G., Ben-Haim A. A novel method for non-fluoroscoic catheter-based electroanatomical mapping of the heart. In vitro and in vivo accuracy results. Circulation. 95:1997;1611-1622.
    • (1997) Circulation , vol.95 , pp. 1611-1622
    • Gepstein, L.1    Hayam, G.2    Ben-Haim, A.3
  • 86
    • 0031440929 scopus 로고    scopus 로고
    • Three dimensional electromagnetic catheter technology: Electroanatomical mapping of the right atrium and ablation of ectopic atrial tachycardia
    • Kottkamp H., Hindricks G., Breithardt G., Borggrefe M. Three dimensional electromagnetic catheter technology: electroanatomical mapping of the right atrium and ablation of ectopic atrial tachycardia. J Cardiovasc Electrophysiol. 8:1997;1332-1337.
    • (1997) J Cardiovasc Electrophysiol , vol.8 , pp. 1332-1337
    • Kottkamp, H.1    Hindricks, G.2    Breithardt, G.3    Borggrefe, M.4
  • 87
    • 0021844035 scopus 로고
    • Regional differences in the electrical activity of the rabbit sinus node
    • Kodama I., Boyett M.R. Regional differences in the electrical activity of the rabbit sinus node. Pflüger's Arch. 404:1985;214-226.
    • (1985) Pflüger's Arch , vol.404 , pp. 214-226
    • Kodama, I.1    Boyett, M.R.2
  • 88
    • 0017191157 scopus 로고
    • Membrane currents in the rabbit sinoatrial node cell as studied by the double microelectrode method
    • Noma A., Irisawa H. Membrane currents in the rabbit sinoatrial node cell as studied by the double microelectrode method. Pflüger's Arch. 364:1976;45-52.
    • (1976) Pflüger's Arch , vol.364 , pp. 45-52
    • Noma, A.1    Irisawa, H.2
  • 90
    • 0030757415 scopus 로고    scopus 로고
    • + currents in pacemaker activity in the sinoatrial node
    • + currents in pacemaker activity in the sinoatrial node. Am J Physiol. 272:1997;H2793-H2806.
    • (1997) Am J Physiol , vol.272 , pp. 2793-H2806
    • Kodama, I.1    Nikmaram, M.R.2    Boyett, M.R.3
  • 91
    • 0023412161 scopus 로고
    • The intrinsic cycle length in small pieces isolated from the rabbit sinoatrial node
    • Opthof T., VanGinneken A.C.G., Bouman L.N., Jongsma H.J. The intrinsic cycle length in small pieces isolated from the rabbit sinoatrial node. J Mol Cell Cardiol. 19:1987;923-934.
    • (1987) J Mol Cell Cardiol , vol.19 , pp. 923-934
    • Opthof, T.1    Vanginneken, A.C.G.2    Bouman, L.N.3    Jongsma, H.J.4
  • 92
    • 0023232079 scopus 로고
    • The influence of the atrial myocardium on impulse formation in the rabbit sinus node
    • Kirchhof C.J.H.J., Bonke F.I.M., Allessie M.A., Lammers W.J.E.P. The influence of the atrial myocardium on impulse formation in the rabbit sinus node. Pflüger's Arch. 410:1987;198-203.
    • (1987) Pflüger's Arch , vol.410 , pp. 198-203
    • Kirchhof, C.J.H.J.1    Bonke, F.I.M.2    Allessie, M.A.3    Lammers, W.J.E.P.4
  • 93
    • 43949168390 scopus 로고
    • Simulating cardiac sinus and atrial network dynamics on the connection machine
    • Winslow R.L., Kimball A.L., Varghese A., Noble D. Simulating cardiac sinus and atrial network dynamics on the connection machine. Physica D. 3:1993;281-298.
    • (1993) Physica D , vol.3 , pp. 281-298
    • Winslow, R.L.1    Kimball, A.L.2    Varghese, A.3    Noble, D.4
  • 95
    • 0028807627 scopus 로고
    • Modulation of pacemaker activity of sinoatrial node cells by electrical load imposed by an atrial cell model
    • Watanabe E.-I., Honjo H., Anno T., et al. Modulation of pacemaker activity of sinoatrial node cells by electrical load imposed by an atrial cell model. Am J Physiol. 269:1995;H1735-H1742.
    • (1995) Am J Physiol , vol.269 , pp. 1735-H1742
    • Watanabe, E.-I.1    Honjo, H.2    Anno, T.3
  • 96
    • 0019195355 scopus 로고
    • Characterization of refractoriness in the sinus node of the rabbit
    • Kerr C.R., Prystowsky E.N., Browning D.J., Strauss H.C. Characterization of refractoriness in the sinus node of the rabbit. Circ Res. 47:1980;742-756.
    • (1980) Circ Res , vol.47 , pp. 742-756
    • Kerr, C.R.1    Prystowsky, E.N.2    Browning, D.J.3    Strauss, H.C.4
  • 97
    • 0028244604 scopus 로고
    • Ultra-slow voltage-dependent inactivation of the calcium current in guinea-pig and ferret ventricular myocytes
    • Boyett M.R., Honjo H., Harrison S.M., Zang W.-J., Kirby M.S. Ultra-slow voltage-dependent inactivation of the calcium current in guinea-pig and ferret ventricular myocytes. Pflüger's Arch. 428:1994;39-50.
    • (1994) Pflüger's Arch , vol.428 , pp. 39-50
    • Boyett, M.R.1    Honjo, H.2    Harrison, S.M.3    Zang, W.-J.4    Kirby, M.S.5
  • 98
    • 33750721034 scopus 로고    scopus 로고
    • Inactivation of the calcium current is involved in overdrive suppression of rabbit sinoatrial node cells
    • Watanabe E.-I., Honjo H., Boyett M.R., Kodama I., Toyama J. Inactivation of the calcium current is involved in overdrive suppression of rabbit sinoatrial node cells. Am J Physiol. 271:1996;H2097-H2107.
    • (1996) Am J Physiol , vol.271 , pp. 2097-H2107
    • Watanabe, E.-I.1    Honjo, H.2    Boyett, M.R.3    Kodama, I.4    Toyama, J.5
  • 99
    • 0018176582 scopus 로고
    • Dual excitatory channels in the sinus node
    • Lipsius S.L., Vassalle M. Dual excitatory channels in the sinus node. J Mol Cell Cardiol. 10:1978;753-767.
    • (1978) J Mol Cell Cardiol , vol.10 , pp. 753-767
    • Lipsius, S.L.1    Vassalle, M.2
  • 102
    • 0031574245 scopus 로고    scopus 로고
    • Ionic currents during sustained pacemaker activity in rabbit sino-atrial myocytes
    • Zaza A., Micheletti M., Brioschi A., Rocchetti M. Ionic currents during sustained pacemaker activity in rabbit sino-atrial myocytes. J Physiol. 505:1999;677-688.
    • (1999) J Physiol , vol.505 , pp. 677-688
    • Zaza, A.1    Micheletti, M.2    Brioschi, A.3    Rocchetti, M.4
  • 103
    • 0008325336 scopus 로고    scopus 로고
    • Na, in the periphery of the sinoatrial node helps the node to drive the surrounding atrial muscle
    • (Abstract)
    • Na, in the periphery of the sinoatrial node helps the node to drive the surrounding atrial muscle. J Physiol. 506:1998;54P-55P. (Abstract).
    • (1998) J Physiol , vol.506
    • Zhang, H.1    Boyett, M.R.2    Holden, A.V.3    Honjo, H.4    Kodama, I.5
  • 104
    • 0002589506 scopus 로고
    • The cardiac calcium-independent transient outward potassium current: Kinetics, molecular properties, and role in ventricular repolarization
    • D.P. Zipes, & J. Jalife. Philadelphia: W.B. Saunders
    • Campbell D.L., Rasmusson R.L., Comer M.B., Strauss H.C. The cardiac calcium-independent transient outward potassium current: kinetics, molecular properties, and role in ventricular repolarization. Zipes D.P., Jalife J. Cardiac electrophysiology: from cell to bedside. 1995;83-96 W.B. Saunders, Philadelphia.
    • (1995) Cardiac Electrophysiology: From Cell to Bedside , pp. 83-96
    • Campbell, D.L.1    Rasmusson, R.L.2    Comer, M.B.3    Strauss, H.C.4
  • 105
    • 0028837379 scopus 로고
    • + channel in rabbit sinoatrial node cells
    • + channel in rabbit sinoatrial node cells. Am J Physiol. 269:1995;H443-H452.
    • (1995) Am J Physiol , vol.269 , pp. 443-H452
    • Ito, H.1    Ono, K.2
  • 106
    • 0034077364 scopus 로고    scopus 로고
    • Characterisation of the transient outward current in rabbit sinoatrial node cells
    • Lei M., Honjo H., Boyett M.R. Characterisation of the transient outward current in rabbit sinoatrial node cells. Cardiovasc Res. 46:2000;433-441.
    • (2000) Cardiovasc Res , vol.46 , pp. 433-441
    • Lei, M.1    Honjo, H.2    Boyett, M.R.3
  • 107
    • 0022539840 scopus 로고
    • Two electrophysiologically distinct types of cultured pacemaker cells from rabbit sinoatrial node
    • Nathan R.D. Two electrophysiologically distinct types of cultured pacemaker cells from rabbit sinoatrial node. Am J Physiol. 250:1986;H325-H329.
    • (1986) Am J Physiol , vol.250 , pp. 325-H329
    • Nathan, R.D.1
  • 108
    • 0032938098 scopus 로고    scopus 로고
    • Heterogeneity of 4-aminopyridine sensitive current in rabbit sinoatrial node cells
    • Honjo H., Lei M., Boyett M.R., Kodama I. Heterogeneity of 4-aminopyridine sensitive current in rabbit sinoatrial node cells. Am J Physiol. 276:1999;H1295-H1304.
    • (1999) Am J Physiol , vol.276 , pp. 1295-H1304
    • Honjo, H.1    Lei, M.2    Boyett, M.R.3    Kodama, I.4
  • 109
    • 0026524968 scopus 로고
    • Delayed rectification in single cells isolated from guinea-pig sinoatrial node
    • Anumonwo J.M.B., Freeman L.C., Kwok W.M., Kass R.S. Delayed rectification in single cells isolated from guinea-pig sinoatrial node. Am J Physiol. 262:1992;H921-H925.
    • (1992) Am J Physiol , vol.262 , pp. 921-H925
    • Anumonwo, J.M.B.1    Freeman, L.C.2    Kwok, W.M.3    Kass, R.S.4
  • 110
    • 0029762672 scopus 로고    scopus 로고
    • K, in rabbit sino-atrial node cells
    • K, in rabbit sino-atrial node cells. Exp Physiol. 81:1996;725-741.
    • (1996) Exp Physiol , vol.81 , pp. 725-741
    • Lei, M.1    Brown, H.F.2
  • 111
    • 0028935894 scopus 로고
    • Effects of delayed rectifier current blockade by E-4031 on impulse generation in single sinoatrial nodal myocytes of the rabbit
    • Verheijck E.E., van Ginneken A.C.G., Bourier J., Bouman L.N. Effects of delayed rectifier current blockade by E-4031 on impulse generation in single sinoatrial nodal myocytes of the rabbit. Circ Res. 76:1995;607-615.
    • (1995) Circ Res , vol.76 , pp. 607-615
    • Verheijck, E.E.1    Van Ginneken, A.C.G.2    Bourier, J.3    Bouman, L.N.4
  • 112
    • 0028895513 scopus 로고
    • + current in sinoatrial node pacemaker activity
    • + current in sinoatrial node pacemaker activity. Am J Physiol. 269:1995;H453-H462.
    • (1995) Am J Physiol , vol.269 , pp. 453-H462
    • Ono, K.1    Ito, H.2
  • 114
    • 0028939888 scopus 로고
    • The onset and autonomic regulation of cardiac pacemaker activity: Relevance of the f current
    • DiFrancesco D. The onset and autonomic regulation of cardiac pacemaker activity: relevance of the f current. Cardiovasc Res. 29:1995;449-456.
    • (1995) Cardiovasc Res , vol.29 , pp. 449-456
    • Difrancesco, D.1
  • 116
    • 0029048044 scopus 로고
    • Ionic basis of the chronotropic effect of acetylcholine on the rabbit sinoatrial node
    • Boyett M.R., Kodama I., Honjo H., et al. Ionic basis of the chronotropic effect of acetylcholine on the rabbit sinoatrial node. Cardiovasc Res. 29:1995;867-878.
    • (1995) Cardiovasc Res , vol.29 , pp. 867-878
    • Boyett, M.R.1    Kodama, I.2    Honjo, H.3
  • 118
    • 0020519287 scopus 로고
    • Does the 'pacemaker current' generate the diastolic depolarization in the rabbit SA node cells?
    • Noma A., Morad M., Irisawa H. Does the 'pacemaker current' generate the diastolic depolarization in the rabbit SA node cells? Pflüger's Arch. 397:1983;190-194.
    • (1983) Pflüger's Arch , vol.397 , pp. 190-194
    • Noma, A.1    Morad, M.2    Irisawa, H.3
  • 119
    • 0014128428 scopus 로고
    • Application of computer techniques to the detection and analysis of spontaneous P-wave variations
    • Brody D.A., Woolsey M.D., Arzbaecher R.C. Application of computer techniques to the detection and analysis of spontaneous P-wave variations. Circulation. 36:1967;359-371.
    • (1967) Circulation , vol.36 , pp. 359-371
    • Brody, D.A.1    Woolsey, M.D.2    Arzbaecher, R.C.3
  • 120
    • 0013893627 scopus 로고
    • The configuration of the P wave during mild exercise
    • Irisawa H., Seyama I. The configuration of the P wave during mild exercise. Am Heart J. 71:1966;467-472.
    • (1966) Am Heart J , vol.71 , pp. 467-472
    • Irisawa, H.1    Seyama, I.2
  • 121
    • 0014481851 scopus 로고
    • Serial P wave changes in acute myocardial infarction
    • Grosman J.I., Delman A.J. Serial P wave changes in acute myocardial infarction. Am Heart J. 77:1969;336-341.
    • (1969) Am Heart J , vol.77 , pp. 336-341
    • Grosman, J.I.1    Delman, A.J.2
  • 122
    • 0018230278 scopus 로고
    • Multicentric origin of the atrial depolarization wave: The pacemaker complex. Relation to dynamics of atrial conduction, P-wave changes and heart rate control
    • Boineau J.P., Schuessler R.B., Mooney C.R., et al. Multicentric origin of the atrial depolarization wave: the pacemaker complex. Relation to dynamics of atrial conduction, P-wave changes and heart rate control. Circulation. 58:1978;1036-1048.
    • (1978) Circulation , vol.58 , pp. 1036-1048
    • Boineau, J.P.1    Schuessler, R.B.2    Mooney, C.R.3
  • 123
    • 0019061764 scopus 로고
    • Widespread distribution and rate differentiation of the atrial pacemaker complex
    • Boineau J.P., Schuessler R.B., Hackel D.B., et al. Widespread distribution and rate differentiation of the atrial pacemaker complex. Am J Physiol. 239:1980;H406-H415.
    • (1980) Am J Physiol , vol.239 , pp. 406-H415
    • Boineau, J.P.1    Schuessler, R.B.2    Hackel, D.B.3
  • 124
    • 0020858198 scopus 로고
    • Quantitative relation between sites of atrial muscle origin and cycle length
    • Boineau J.P., Schuessler R.B., Roeske W.R., et al. Quantitative relation between sites of atrial muscle origin and cycle length. Am J Physiol. 245:1983;H781-H789.
    • (1983) Am J Physiol , vol.245 , pp. 781-H789
    • Boineau, J.P.1    Schuessler, R.B.2    Roeske, W.R.3
  • 125
    • 0014493685 scopus 로고
    • Change of cardiac rhythm in the rabbit after an atrial beat
    • Bonke F.I.M., Bouman L.N., van Rijn H.E. Change of cardiac rhythm in the rabbit after an atrial beat. Circ Res. 24:1969;533-544.
    • (1969) Circ Res , vol.24 , pp. 533-544
    • Bonke, F.I.M.1    Bouman, L.N.2    Van Rijn, H.E.3
  • 126
    • 0343708727 scopus 로고
    • Interaction of adrenaline and acetylcholine on sinus node function
    • L.N. Bouman, & H.J. Jongsma. The Hague: Martinus Nijhoff
    • Mackaay A.J.C., Opthof T., Bleeker W.K., Jongsma H.J., Bouman L.N. Interaction of adrenaline and acetylcholine on sinus node function. Bouman L.N., Jongsma H.J. Cardiac rate and rhythm. 1982;507-523 Martinus Nijhoff, The Hague.
    • (1982) Cardiac Rate and Rhythm , pp. 507-523
    • Mackaay, A.J.C.1    Opthof, T.2    Bleeker, W.K.3    Jongsma, H.J.4    Bouman, L.N.5
  • 127
    • 0018603040 scopus 로고
    • Phasic effects of vagal stimulation on pacemaker activity of the isolated sinus node of the young cat
    • Jalife J., Moe G.K. Phasic effects of vagal stimulation on pacemaker activity of the isolated sinus node of the young cat. Circ Res. 45:1979;595-607.
    • (1979) Circ Res , vol.45 , pp. 595-607
    • Jalife, J.1    Moe, G.K.2
  • 128
    • 0018855414 scopus 로고
    • Interaction of adrenaline and acetylcholine on cardiac pacemaker function. Functional inhomogeneity of the rabbit sinus node
    • Mackaay A.J.C., Op't Hof T., Bleeker W.K., Jongsma H.J., Bouman L.N. Interaction of adrenaline and acetylcholine on cardiac pacemaker function. Functional inhomogeneity of the rabbit sinus node. J Pharmacol Exp Ther. 214:1980;417-422.
    • (1980) J Pharmacol Exp Ther , vol.214 , pp. 417-422
    • Mackaay, A.J.C.1    Op't Hof, T.2    Bleeker, W.K.3    Jongsma, H.J.4    Bouman, L.N.5
  • 129
    • 0018858004 scopus 로고
    • The effect of ouabain on the isolated sinus node preparation of the rabbit studied with microelectrodes
    • Steinbeck G., Bonke F.I.M., Allesie M.A., Lammers W.J.E.P. The effect of ouabain on the isolated sinus node preparation of the rabbit studied with microelectrodes. Circ Res. 46:1980;406-414.
    • (1980) Circ Res , vol.46 , pp. 406-414
    • Steinbeck, G.1    Bonke, F.I.M.2    Allesie, M.A.3    Lammers, W.J.E.P.4
  • 130
    • 0005390125 scopus 로고
    • Pacemaker shift in the sinus node: Effects of vagal stimulation, temperature and reduction of extracellular calcium
    • F.I.M. Bonke. The Hague: Martinus Nijhoff
    • Bouman L.N., Mackaay A.J.C., Bleeker W.K., Becker A.E. Pacemaker shift in the sinus node: effects of vagal stimulation, temperature and reduction of extracellular calcium. Bonke F.I.M. The sinus node, structure, function and clinical relevance. 1978;245-257 Martinus Nijhoff, The Hague.
    • (1978) The Sinus Node, Structure, Function and Clinical Relevance , pp. 245-257
    • Bouman, L.N.1    Mackaay, A.J.C.2    Bleeker, W.K.3    Becker, A.E.4
  • 131
    • 0018868542 scopus 로고
    • Temperature dependence of the chronotropic action of calcium: Functional inhomogeneity of the rabbit sinus node
    • Mackaay A.J.C., Bleeker W.M., Opthof T., Bouman L.N. Temperature dependence of the chronotropic action of calcium: functional inhomogeneity of the rabbit sinus node. J Mol Cell Cardiol. 12:1980;433-443.
    • (1980) J Mol Cell Cardiol , vol.12 , pp. 433-443
    • Mackaay, A.J.C.1    Bleeker, W.M.2    Opthof, T.3    Bouman, L.N.4
  • 133
    • 0014750385 scopus 로고
    • Sinoatrial region of cat and rabbit hearts resulting from increase of extracellular potassium
    • Lu H.-H. Sinoatrial region of cat and rabbit hearts resulting from increase of extracellular potassium. Circ Res. 26:1970;339-346.
    • (1970) Circ Res , vol.26 , pp. 339-346
    • Lu, H.-H.1
  • 134
  • 135
    • 4243965194 scopus 로고    scopus 로고
    • A computer model of pacemaker shift within the rabbit sinoatrial node
    • (Abstract)
    • Zhang H., Boyett M.R., Holden A.V., Honjo H., Kodama I. A computer model of pacemaker shift within the rabbit sinoatrial node. J Physiol. 504:1997;70P. (Abstract).
    • (1997) J Physiol , vol.504
    • Zhang, H.1    Boyett, M.R.2    Holden, A.V.3    Honjo, H.4    Kodama, I.5
  • 136
    • 0000056638 scopus 로고    scopus 로고
    • 2+ handling proteins in sinoatrial node
    • (Abstract)
    • 2+ handling proteins in sinoatrial node. Biophys J. 78:2000;106A. (Abstract).
    • (2000) Biophys J , vol.78
    • Lei, M.1    Musa, H.2    Honjo, H.3
  • 137
    • 0024810920 scopus 로고
    • Mechanisms of impulse generation in isolated cells from the rabbit sinoatrial node
    • Oei H.I., van Ginneken A.C.G., Jongsma H.J., Bouman L.N. Mechanisms of impulse generation in isolated cells from the rabbit sinoatrial node. J Mol Cell Cardiol. 21:1989;1137-1149.
    • (1989) J Mol Cell Cardiol , vol.21 , pp. 1137-1149
    • Oei, H.I.1    Van Ginneken, A.C.G.2    Jongsma, H.J.3    Bouman, L.N.4
  • 138
    • 0029962743 scopus 로고    scopus 로고
    • Correlation between electrical activity and the size of rabbit sinoatrial node cells
    • Honjo H., Boyett M.R., Kodama I., Toyama J. Correlation between electrical activity and the size of rabbit sinoatrial node cells. J Physiol. 496:1996;795-808.
    • (1996) J Physiol , vol.496 , pp. 795-808
    • Honjo, H.1    Boyett, M.R.2    Kodama, I.3    Toyama, J.4
  • 139
    • 0007567323 scopus 로고    scopus 로고
    • K,s in rabbit sinoatrial node cells
    • Abstract
    • K,s in rabbit sinoatrial node cells. J Physiol. 521:1999;19P-20P. Abstract.
    • (1999) J Physiol , vol.521
    • Lei, M.1    Boyett, M.R.2
  • 140
    • 33750708307 scopus 로고    scopus 로고
    • Model clamp and its application to synchronization of rabbit sinoatrial node cells
    • Wilders R., Verheijck E.E., Kumar R., et al. Model clamp and its application to synchronization of rabbit sinoatrial node cells. Am J Physiol. 271:1996;H2168-H2182.
    • (1996) Am J Physiol , vol.271 , pp. 2168-H2182
    • Wilders, R.1    Verheijck, E.E.2    Kumar, R.3
  • 141
    • 0025830164 scopus 로고
    • Pacemaker activity of the rabbit sinoatrial node. A comparison of mathematical models
    • Wilders R., Jongsma H.J., van Ginneken A.C.G. Pacemaker activity of the rabbit sinoatrial node. A comparison of mathematical models. Biophys J. 60:1991;1202-1216.
    • (1991) Biophys J , vol.60 , pp. 1202-1216
    • Wilders, R.1    Jongsma, H.J.2    Van Ginneken, A.C.G.3
  • 142
    • 0028913302 scopus 로고
    • A sustained inward current activated at the diastolic potential range in rabbit sino-atrial node cells
    • Guo J., Ono K., Noma A. A sustained inward current activated at the diastolic potential range in rabbit sino-atrial node cells. J Physiol. 483:1995;1-13.
    • (1995) J Physiol , vol.483 , pp. 1-13
    • Guo, J.1    Ono, K.2    Noma, A.3
  • 143
    • 0031012419 scopus 로고    scopus 로고
    • The sustained inward current in sino-atrial node cells of guinea-pig heart
    • Gou J., Mitsuiye T., Noma A. The sustained inward current in sino-atrial node cells of guinea-pig heart. Pflüger's Arch. 433:1997;390-396.
    • (1997) Pflüger's Arch , vol.433 , pp. 390-396
    • Gou, J.1    Mitsuiye, T.2    Noma, A.3
  • 144
    • 0023874297 scopus 로고
    • Contribution of two types of calcium currents to the pacemaker potentials of rabbit sino-atrial node cells
    • Hagiwara N., Irisawa H., Kameyama M. Contribution of two types of calcium currents to the pacemaker potentials of rabbit sino-atrial node cells. J Physiol. 395:1988;233-253.
    • (1988) J Physiol , vol.395 , pp. 233-253
    • Hagiwara, N.1    Irisawa, H.2    Kameyama, M.3
  • 145
    • 0002174099 scopus 로고    scopus 로고
    • What role do T-type calcium channels play in cardiac pacemaker activity
    • R.W. Tsien, J.-P. Clozel, & J. Nargeot. Chester: Adis International
    • Lei M., Brown H.F., Noble D. What role do T-type calcium channels play in cardiac pacemaker activity. Tsien R.W., Clozel J.-P., Nargeot J. Low-voltage-activated T-type calcium channels. 1998;103-109 Adis International, Chester.
    • (1998) Low-voltage-activated T-type Calcium Channels , pp. 103-109
    • Lei, M.1    Brown, H.F.2    Noble, D.3
  • 146
    • 0030725925 scopus 로고    scopus 로고
    • Ionic basis of ryanodine's negative chronotropic effect on pacemaker cells isolated from the sinoatrial node
    • Li J., Qu J., Nathan R.D. Ionic basis of ryanodine's negative chronotropic effect on pacemaker cells isolated from the sinoatrial node. Am J Physiol. 273:1997;H2481-H2489.
    • (1997) Am J Physiol , vol.273 , pp. 2481-H2489
    • Li, J.1    Qu, J.2    Nathan, R.D.3
  • 147
    • 0026530016 scopus 로고
    • Background current in sino-atrial node cells of the rabbit heart
    • Hagiwara N., Irisawa H., Kasanuki H., Hosada S. Background current in sino-atrial node cells of the rabbit heart. J Physiol. 448:1992;53-72.
    • (1992) J Physiol , vol.448 , pp. 53-72
    • Hagiwara, N.1    Irisawa, H.2    Kasanuki, H.3    Hosada, S.4
  • 148
    • 0030048158 scopus 로고    scopus 로고
    • Sodium-potassium pump current in rabbit sino-atrial node cells
    • Sakai R., Hagiwara N., Matsuda N., Kasanuki H., Hosoda S. Sodium-potassium pump current in rabbit sino-atrial node cells. J Physiol. 490:1996;51-62.
    • (1996) J Physiol , vol.490 , pp. 51-62
    • Sakai, R.1    Hagiwara, N.2    Matsuda, N.3    Kasanuki, H.4    Hosoda, S.5
  • 149
    • 0028213435 scopus 로고
    • + channels in rabbit sino-atrial node cells
    • + channels in rabbit sino-atrial node cells. J Physiol. 476:1994;55-68.
    • (1994) J Physiol , vol.476 , pp. 55-68
    • Ito, H.1    Ono, K.2    Noma, A.3
  • 151
    • 0031080236 scopus 로고    scopus 로고
    • ATP-activated cationic current in rabbit sino-atrial node cells
    • Shoda M., Hagiwara N., Kasanuki H., Hosada S. ATP-activated cationic current in rabbit sino-atrial node cells. J Mol Cell Cardiol. 29:1997;689-695.
    • (1997) J Mol Cell Cardiol , vol.29 , pp. 689-695
    • Shoda, M.1    Hagiwara, N.2    Kasanuki, H.3    Hosada, S.4
  • 152
    • 0026775110 scopus 로고
    • Stretch-activated anion currents of rabbit cardiac myocytes
    • Hagiwara N., Masuda H., Shoda M., Irisawa H. Stretch-activated anion currents of rabbit cardiac myocytes. J Physiol. 456:1992;285-302.
    • (1992) J Physiol , vol.456 , pp. 285-302
    • Hagiwara, N.1    Masuda, H.2    Shoda, M.3    Irisawa, H.4
  • 153
    • 0033135309 scopus 로고    scopus 로고
    • 2+ release in amphibian pacemaker cells
    • 2+ release in amphibian pacemaker cells. J Physiol. 516:1999;793-804.
    • (1999) J Physiol , vol.516 , pp. 793-804
    • Ju, Y.-K.1    Allen, D.G.2
  • 154
    • 0032056007 scopus 로고    scopus 로고
    • 2+ exchange current in isolated toad pacemaker cells
    • 2+ exchange current in isolated toad pacemaker cells. J Physiol. 508:1998;153-166.
    • (1998) J Physiol , vol.508 , pp. 153-166
    • Ju, Y.-K.1    Allen, D.G.2
  • 155
    • 0029741590 scopus 로고    scopus 로고
    • Possible role of calcium release from the sarcoplasmic reticulum in pacemaking in guinea-pig sino-atrial node
    • Rigg L., Terrar D.A. Possible role of calcium release from the sarcoplasmic reticulum in pacemaking in guinea-pig sino-atrial node. Exp Physiol. 81:1996;877-880.
    • (1996) Exp Physiol , vol.81 , pp. 877-880
    • Rigg, L.1    Terrar, D.A.2
  • 156
    • 0004715826 scopus 로고    scopus 로고
    • Heterogeneous expression of the ryanodine receptor in the rabbit sinoatrial node
    • Abstract
    • Musa H., Lei M., Dobrzynski H., et al. Heterogeneous expression of the ryanodine receptor in the rabbit sinoatrial node. J Physiol. 521:1999;25P-26P. Abstract.
    • (1999) J Physiol , vol.521
    • Musa, H.1    Lei, M.2    Dobrzynski, H.3
  • 157
    • 0019277122 scopus 로고
    • Reconstruction of sinoatrial node pacemaker potential based on the voltage clamp experiments
    • Yanighara K., Noma A., Irisawa H. Reconstruction of sinoatrial node pacemaker potential based on the voltage clamp experiments. Jpn J Physiol. 30:1980;841-857.
    • (1980) Jpn J Physiol , vol.30 , pp. 841-857
    • Yanighara, K.1    Noma, A.2    Irisawa, H.3
  • 158
    • 0021226282 scopus 로고
    • A model of sino-atrial node electrical activity based on a modification of the DiFrancesco-Noble (1984) equations
    • Noble D., Noble S.J. A model of sino-atrial node electrical activity based on a modification of the DiFrancesco-Noble (1984) equations. Proc R Soc Lond B. 222:1984;295-304.
    • (1984) Proc R Soc Lond B , vol.222 , pp. 295-304
    • Noble, D.1    Noble, S.J.2
  • 159
    • 0028115490 scopus 로고
    • A mathematical model of a rabbit sinoatrial node cell
    • Demir S.S., Clark J.W., Murphey C.R., Giles W.R. A mathematical model of a rabbit sinoatrial node cell. Am J Physiol. 266:1994;C832-C852.
    • (1994) Am J Physiol , vol.266 , pp. 832-C852
    • Demir, S.S.1    Clark, J.W.2    Murphey, C.R.3    Giles, W.R.4
  • 160
    • 0027624491 scopus 로고    scopus 로고
    • Modification of DiFrancesco-Noble equations to simulate the effects of vagal stimulation on in vivo mammalian sinoatrial node electrical activity
    • Dokos S., Celler B.G., Lovell N.H. Modification of DiFrancesco-Noble equations to simulate the effects of vagal stimulation on in vivo mammalian sinoatrial node electrical activity. Ann Biomed Eng. 21:1999;321-335.
    • (1999) Ann Biomed Eng , vol.21 , pp. 321-335
    • Dokos, S.1    Celler, B.G.2    Lovell, N.H.3
  • 161
    • 0033858925 scopus 로고    scopus 로고
    • Mathematical models of action potentials in the periphery and centre of the rabbit sinoatrial node
    • Zhang H., Holden A.V., Kodama I., et al. Mathematical models of action potentials in the periphery and centre of the rabbit sinoatrial node. Am J Physiol. 279:2000;H397-H421.
    • (2000) Am J Physiol , vol.279 , pp. 397-H421
    • Zhang, H.1    Holden, A.V.2    Kodama, I.3
  • 162
    • 0008395646 scopus 로고    scopus 로고
    • Hypothesis to explain the block zone protecting the sinoatrial node
    • Zhang H., Holden A.V., Kodama I., et al. Hypothesis to explain the block zone protecting the sinoatrial node. Biophys J. 76:1999;A368-A368.
    • (1999) Biophys J , vol.76 , pp. 368-A368
    • Zhang, H.1    Holden, A.V.2    Kodama, I.3
  • 163
    • 0024598929 scopus 로고
    • Muscarinic modulation of cardiac rate at low acetylcholine concentrations
    • DiFrancesco D., Ducouret P., Robinson R.B. Muscarinic modulation of cardiac rate at low acetylcholine concentrations. Science. 243:1989;669-671.
    • (1989) Science , vol.243 , pp. 669-671
    • Difrancesco, D.1    Ducouret, P.2    Robinson, R.B.3
  • 165
    • 0027394464 scopus 로고
    • Mechanism of muscarinic control of the high-threshold calcium current in rabbit sino-atrial node myocytes
    • Petit-Jacques J., Bois P., Bescond J., Lenfant J. Mechanism of muscarinic control of the high-threshold calcium current in rabbit sino-atrial node myocytes. Pflüger's Arch. 423:1993;21-27.
    • (1993) Pflüger's Arch , vol.423 , pp. 21-27
    • Petit-Jacques, J.1    Bois, P.2    Bescond, J.3    Lenfant, J.4
  • 166
    • 0029944490 scopus 로고    scopus 로고
    • 2+ current and hyperpolarization-activated currents to autonomic agonists in the rabbit sino-atrial node
    • 2+ current and hyperpolarization-activated currents to autonomic agonists in the rabbit sino-atrial node. J Physiol. 491:1996;347-355.
    • (1996) J Physiol , vol.491 , pp. 347-355
    • Zaza, A.1    Robinson, R.B.2    Difrancesco, D.3
  • 167
    • 0027074563 scopus 로고
    • Desensitization to acetylcholine in single sino-atrial node cells isolated from the rabbit heart
    • Honjo H., Kodama I., Zang W.-J., Boyett M.R. Desensitization to acetylcholine in single sino-atrial node cells isolated from the rabbit heart. Am J Physiol. 263:1992;H1779-H1789.
    • (1992) Am J Physiol , vol.263 , pp. 1779-H1789
    • Honjo, H.1    Kodama, I.2    Zang, W.-J.3    Boyett, M.R.4
  • 168
    • 0027925830 scopus 로고
    • Analysis of the effects of vagal stimulation on the sinus venosus of the toad
    • Edwards F.R., Bramich N.J., Hirst G.D.S. Analysis of the effects of vagal stimulation on the sinus venosus of the toad. Philos Trans R Soc Lond B. 341:1993;149-162.
    • (1993) Philos Trans R Soc Lond B , vol.341 , pp. 149-162
    • Edwards, F.R.1    Bramich, N.J.2    Hirst, G.D.S.3
  • 169
    • 0024391383 scopus 로고
    • Effects of vagal stimulation and applied acetylcholine on pacemaker potentials in the guinea-pig heart
    • Campbell G.D., Edwards F.R., Hirst G.D.S., O'Shea J.E. Effects of vagal stimulation and applied acetylcholine on pacemaker potentials in the guinea-pig heart. J Physiol. 415:1989;57-68.
    • (1989) J Physiol , vol.415 , pp. 57-68
    • Campbell, G.D.1    Edwards, F.R.2    Hirst, G.D.S.3    O'Shea, J.E.4
  • 170
    • 0025303085 scopus 로고
    • Effects of vagal stimulation and applied acetylcholine on the arrested sinus venosus of the toad
    • Bywater R.A.R., Campbell G.D., Edwards F.R., Hirst G.D.S. Effects of vagal stimulation and applied acetylcholine on the arrested sinus venosus of the toad. J Physiol. 425:1990;1-27.
    • (1990) J Physiol , vol.425 , pp. 1-27
    • Bywater, R.A.R.1    Campbell, G.D.2    Edwards, F.R.3    Hirst, G.D.S.4
  • 171
    • 0024405250 scopus 로고
    • The effects of vagal stimulation and applied acetylcholine on the sinus venosus of the toad
    • Bywater R.A.R., Campbell G., Edwards F.R., Hirst G.D.S., O'Shea J.E. The effects of vagal stimulation and applied acetylcholine on the sinus venosus of the toad. J Physiol. 415:1989;35-56.
    • (1989) J Physiol , vol.415 , pp. 35-56
    • Bywater, R.A.R.1    Campbell, G.2    Edwards, F.R.3    Hirst, G.D.S.4    O'Shea, J.E.5
  • 172
    • 0028132898 scopus 로고
    • Ionophoretically applied acetylcholine and vagal stimulation in the arrested sinus venosus of the toad, Bufo marinus
    • Bramich N.J., Brock J.A., Edwards F.R., Hirst G.D.S. Ionophoretically applied acetylcholine and vagal stimulation in the arrested sinus venosus of the toad, Bufo marinus. J Physiol. 478:1994;289-300.
    • (1994) J Physiol , vol.478 , pp. 289-300
    • Bramich, N.J.1    Brock, J.A.2    Edwards, F.R.3    Hirst, G.D.S.4
  • 173
    • 0026635717 scopus 로고
    • Effect of transmural vagal stimulation on electrotonic current spread in the rabbit sinoatrial node
    • Duivenvoorden J.J., Bouman L.N., Opthof T., Bukauskas F.F., Jongsma H.J. Effect of transmural vagal stimulation on electrotonic current spread in the rabbit sinoatrial node. Cardiovasc Res. 26:1992;678-686.
    • (1992) Cardiovasc Res , vol.26 , pp. 678-686
    • Duivenvoorden, J.J.1    Bouman, L.N.2    Opthof, T.3    Bukauskas, F.F.4    Jongsma, H.J.5
  • 174
  • 175
    • 0031909974 scopus 로고    scopus 로고
    • Abnormal heart rate regulation in GIRK4 knockout mice
    • Wickman K., Nemec J., Gendler S.J., Clapham D.E. Abnormal heart rate regulation in GIRK4 knockout mice. Neuron. 20:1998;103-114.
    • (1998) Neuron , vol.20 , pp. 103-114
    • Wickman, K.1    Nemec, J.2    Gendler, S.J.3    Clapham, D.E.4
  • 176
    • 0000989314 scopus 로고
    • The action of a single vagal volley on the rhythm of the heart beat
    • Brown G.L., Eccles J.C. The action of a single vagal volley on the rhythm of the heart beat. J Physiol. 82:1934;211-240.
    • (1934) J Physiol , vol.82 , pp. 211-240
    • Brown, G.L.1    Eccles, J.C.2
  • 177
    • 0019439677 scopus 로고
    • Neural regulation of the heart beat
    • Levy M.N., Martin P.J. Neural regulation of the heart beat. Annu Rev Physiol. 43:1981;443-453.
    • (1981) Annu Rev Physiol , vol.43 , pp. 443-453
    • Levy, M.N.1    Martin, P.J.2
  • 178
    • 0026070322 scopus 로고
    • Vagal stimulation of the heartbeat: Muscarinic receptor hypothesis
    • Pappano A.J. Vagal stimulation of the heartbeat: muscarinic receptor hypothesis. J Cardiovasc Electrophysiol. 2:1991;262-273.
    • (1991) J Cardiovasc Electrophysiol , vol.2 , pp. 262-273
    • Pappano, A.J.1
  • 179
    • 0029757349 scopus 로고    scopus 로고
    • Regional differences in the response of the isolated sinoatrial node of the rabbit to vagal stimulation
    • Kodama I., Boyett M.R., Suzuki R., Honjo H., Toyama J. Regional differences in the response of the isolated sinoatrial node of the rabbit to vagal stimulation. J Physiol. 495:1996;785-801.
    • (1996) J Physiol , vol.495 , pp. 785-801
    • Kodama, I.1    Boyett, M.R.2    Suzuki, R.3    Honjo, H.4    Toyama, J.5
  • 180
    • 0029562355 scopus 로고
    • Computer simulation of the electrotonic modulation of pacemaker activity in the sinoatrial node by atrial muscle
    • Toyama J., Boyett M.R., Watanabe E.-I., et al. Computer simulation of the electrotonic modulation of pacemaker activity in the sinoatrial node by atrial muscle. J Electrocardiol. 28:(suppl):1995;212-215.
    • (1995) J Electrocardiol , vol.28 , Issue.SUPPL , pp. 212-215
    • Toyama, J.1    Boyett, M.R.2    Watanabe, E.-I.3
  • 181
    • 0026666499 scopus 로고
    • Vagal stimulation during muscarinic and β-adrenergic blockade increases atrial contractility and heart rate
    • Henning R.V. Vagal stimulation during muscarinic and β-adrenergic blockade increases atrial contractility and heart rate. J Auton Nerv Syst. 40:1992;121-130.
    • (1992) J Auton Nerv Syst , vol.40 , pp. 121-130
    • Henning, R.V.1
  • 182
    • 0031015101 scopus 로고    scopus 로고
    • Effects of vasoactive intestinal polypeptide on heart rate in relation to vagal cardioacceleration in conscious dogs
    • Roossien A., Brunsting J.R., Nijmeijer A., Zaagsma J., Zijlstra W.G. Effects of vasoactive intestinal polypeptide on heart rate in relation to vagal cardioacceleration in conscious dogs. Cardiovasc Res. 33:1997;392-399.
    • (1997) Cardiovasc Res , vol.33 , pp. 392-399
    • Roossien, A.1    Brunsting, J.R.2    Nijmeijer, A.3    Zaagsma, J.4    Zijlstra, W.G.5
  • 183
    • 0018346156 scopus 로고
    • The effect of brief vagal stimulation on the isolated rabbit sinus node
    • Spear J.F., Kronhaus K.D., Moore E.N., Kline R.P. The effect of brief vagal stimulation on the isolated rabbit sinus node. Circ Res. 44:1979;75-88.
    • (1979) Circ Res , vol.44 , pp. 75-88
    • Spear, J.F.1    Kronhaus, K.D.2    Moore, E.N.3    Kline, R.P.4
  • 185
    • 0028849383 scopus 로고
    • Relative densities of muscarinic cholinergic and β-adrenergic receptors in the canine sinoatrial node and their relation to sites of pacemaker activity
    • Beau S.L., Hand D.E., Schuessler R.B., et al. Relative densities of muscarinic cholinergic and β-adrenergic receptors in the canine sinoatrial node and their relation to sites of pacemaker activity. Circ Res. 77:1995;957-963.
    • (1995) Circ Res , vol.77 , pp. 957-963
    • Beau, S.L.1    Hand, D.E.2    Schuessler, R.B.3
  • 186
    • 0024413660 scopus 로고
    • Morphological study of the innervation pattern of the rabbit sinoatrial node
    • Roberts L.A., Slocum G.R., Riley D.A. Morphological study of the innervation pattern of the rabbit sinoatrial node. Am J Anat. 185:1989;74-88.
    • (1989) Am J Anat , vol.185 , pp. 74-88
    • Roberts, L.A.1    Slocum, G.R.2    Riley, D.A.3
  • 187
    • 0034004652 scopus 로고    scopus 로고
    • K, by isoprenaline in rabbit isolated pacemaker cells
    • K, by isoprenaline in rabbit isolated pacemaker cells. Exp Physiol. 85:2000;27-35.
    • (2000) Exp Physiol , vol.85 , pp. 27-35
    • Lei, M.1    Brown, H.F.2    Terrar, D.A.3
  • 188
    • 0012218978 scopus 로고
    • Effect of caesium and β-adrenergic agonists on the rate of spontaneous activity in an isolated rabbit sino-atrial node preparation
    • Abstract
    • Leitch S.P., Brown H.F., Paterson D.J. Effect of caesium and β-adrenergic agonists on the rate of spontaneous activity in an isolated rabbit sino-atrial node preparation. J Physiol. 459:1993;86P. Abstract.
    • (1993) J Physiol , vol.459
    • Leitch, S.P.1    Brown, H.F.2    Paterson, D.J.3
  • 189
    • 0028979091 scopus 로고    scopus 로고
    • f current mediates β-adrenergic enhancement of heart rate but not contractivility in vivo
    • f current mediates β-adrenergic enhancement of heart rate but not contractivility in vivo. Basic Res Cardiol. 90:2000;192-202.
    • (2000) Basic Res Cardiol , vol.90 , pp. 192-202
    • Guth, B.D.1    Diete, T.2
  • 190
    • 0027431136 scopus 로고
    • Effects of sympathetic nerve stimulation on the sino-atrial node of the guinea-pig
    • Choate J.K., Edwards F.R., Hirst G.D.S., O'Shea J.E. Effects of sympathetic nerve stimulation on the sino-atrial node of the guinea-pig. J Physiol. 471:1993;707-727.
    • (1993) J Physiol , vol.471 , pp. 707-727
    • Choate, J.K.1    Edwards, F.R.2    Hirst, G.D.S.3    O'Shea, J.E.4
  • 191
    • 0027440195 scopus 로고
    • Electrophysiology of the ageing rabbit and cat sinoatrial node - A comparative study
    • Alings A.M.W., Bouman L.N. Electrophysiology of the ageing rabbit and cat sinoatrial node - a comparative study. Eur Heart J. 14:1993;1278-1288.
    • (1993) Eur Heart J , vol.14 , pp. 1278-1288
    • Alings, A.M.W.1    Bouman, L.N.2
  • 192
    • 0029923331 scopus 로고    scopus 로고
    • A TTX-sensitive inward sodium current contributes to spontaneous activity in newborn rabbit sino-atrial node cells
    • Baruscotti M., DiFrancesco D., Robinson R.B. A TTX-sensitive inward sodium current contributes to spontaneous activity in newborn rabbit sino-atrial node cells. J Physiol. 492:1996;21-30.
    • (1996) J Physiol , vol.492 , pp. 21-30
    • Baruscotti, M.1    Difrancesco, D.2    Robinson, R.B.3
  • 193
    • 0001918595 scopus 로고    scopus 로고
    • A hypothesis to explain the decline of sinoatrial node function with age
    • (Abstract)
    • Zhang H., Boyett M.R., Holden A.V., Honjo H., Kodama I. A hypothesis to explain the decline of sinoatrial node function with age. J Physiol. 511:1998;76P-77P. (Abstract).
    • (1998) J Physiol , vol.511
    • Zhang, H.1    Boyett, M.R.2    Holden, A.V.3    Honjo, H.4    Kodama, I.5


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